دورية أكاديمية
Rationale and design of the peripheral nerve tumor registry: an observational cohort study
| العنوان: | Rationale and design of the peripheral nerve tumor registry: an observational cohort study |
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| المؤلفون: | Dengler, N.F., Scholz, C., Beck, J., Uerschels, A.-K., Sure, U., Scheller, C., Strauss, C., Martin, D., Schackert, G., Heinen, C., Woitzik, J., McLean, A.L., Rosahl, S.K., Kolbenschlag, J., Heinzel, J., Schuhmann, M., Tatagiba, M.S., Guerra, W.K.-W., Schroeder, H.W.S., Vetrano, I.G., Ahmadi, R., Unterberg, A., Reinsch, J., Zdunczyk, A., Unteroberdoerster, M., Vajkoczy, P., Wehner, S., Becker, M., Matthies, C., Pérez-Tejón, J., Dubuisson, Annie, Barrone, D.G., Trivedi, R., Capone, C., Ferraresi, S., Kraschl, J., Kretschmer, T., Dombert, T., Staub, F., Ronellenfitsch, M., Marquardt, G., Prinz, V., Czabanka, M., Carolus, A., Braun, V., König, R., Antoniadis, G., Wirtz, C.R., Rasulic, L., Pedro, M.T. |
| المصدر: | Neurological Research, 45 (1), 81 - 85 (2023) |
| بيانات النشر: | Taylor and Francis Ltd. |
| سنة النشر: | 2023 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | neurofibroma, Peripheral nerve tumor, registry, schwannoma, leucine zipper like transcriptional regulator 1, protein, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1, unclassified drug, adolescent, Article, cancer registry, child, cohort analysis, computer assisted tomography, female, follow up, human, male, multicenter study, neurologic examination, nuclear magnetic resonance imaging, observational study, positron emission tomography, prospective study, quality of life, standardized uptake value, systematic review, tumor volume, clinical trial, Europe |
| الوصف: | peer reviewed ; Aim: Peripheral nerve tumors (PNT) are rare lesions. To date, no systematic multicenter studies on epidemiology, clinical symptoms, treatment strategies and outcomes, genetic and histopathologic features, as well as imaging characteristics of PNT were published. The main goal of our PNT Registry is the systematic multicenter investigation to improve our understanding of PNT and to assist future interventional studies in establishing hypotheses, determining potential endpoints, and assessing treatment efficacy. Methods: Aims of the PNT registry were set at the 2015 Meeting of the Section of Peripheral Nerve Surgery of the German Society of Neurosurgery. A study protocol was developed by specialists in PNT care. A minimal data set on clinical status, treatment types and outcomes is reported by each participating center at initial contact with the patient and after 1 year, 2 years, and 5 years. Since the study is coordinated by the Charité Berlin, the PNR Registry was approved by the Charité ethics committee (EA4/058/17) and registered with the German Trials Registry (www.drks.de). On a national level, patient inclusion began in June 2016. The registry was rolled out across Europe at the 2019 meeting of the European Association of Neurosurgery in Dublin. Results: Patient recruitment has been initiated at 10 centers throughout Europe and 14 additional centers are currently applying for local ethics approval. Conclusion: To date, the PNT registry has grown into an international study group with regular scientific and clinical exchange awaiting the first results of the retrospective study arm. © 2022 Informa UK Limited, trading as Taylor & Francis Group. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0161-6412 1743-1328 |
| العلاقة: | urn:issn:0161-6412; urn:issn:1743-1328; https://orbi.uliege.be/handle/2268/303694Test; info:hdl:2268/303694; https://orbi.uliege.be/bitstream/2268/303694/1/Rational%20and%20design%20of%20the%20peripheral%20nerve%20tumor%20registry.pdfTest; scopus-id:2-s2.0-85139653540; info:pmid:36208460 |
| DOI: | 10.1080/01616412.2022.2129762 |
| الإتاحة: | https://doi.org/10.1080/01616412.2022.2129762Test https://orbi.uliege.be/handle/2268/303694Test https://orbi.uliege.be/bitstream/2268/303694/1/Rational%20and%20design%20of%20the%20peripheral%20nerve%20tumor%20registry.pdfTest |
| حقوق: | open access ; http://purl.org/coar/access_right/c_abf2Test ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.E68E0825 |
| قاعدة البيانات: | BASE |
| تدمد: | 01616412 17431328 |
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| DOI: | 10.1080/01616412.2022.2129762 |