التفاصيل البيبلوغرافية
| العنوان: |
H-2 Private Specificity of In Vivo-Sensitized Lymphocytes Studied by Adsorption on Fibroblast Monolayers. |
| المؤلفون: |
Jørgensen, P. N., Güttler, F., Rubin, B. |
| المصدر: |
Scandinavian Journal of Immunology; Jun1975, Vol. 4 Issue 4, p383-389, 7p |
| مصطلحات موضوعية: |
H-2 locus, IMMUNOGENETICS, LYMPHOCYTES, LEUCOCYTES, CANCER immunotherapy, TUMOR immunology, IMMUNE system, IMMUNOLOGY |
| مستخلص: |
Spleen cells or thymocytes immune to one H-2 genotype are cytotoxic to allogeneic target cells of a third-party genotype, provided the target shares private specificities determined by either the H-2K or the H-2D locus of the H-2 complex with the H-2 genotype used for sensitization in vivo. The present results on elimination of cytotoxicity to specificities determined by one of the H-2 loci after adsorption of the immune lymphoid cells onto fibroblasts bearing this specificity suggest a state of diversity among effector lymphocytes reactive to the antigens determined by either the H-2K or the H-2D locus of the H-2 complex. Thymus cells activated in vivo were less specifically adsorbable than spleen cells of tumor-allografted mice. [ABSTRACT FROM AUTHOR] |
|
Copyright of Scandinavian Journal of Immunology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
