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1دورية أكاديمية
المؤلفون: Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A. Dalby, Duygu Dikicioglu
مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Biotechnology, Cancer, Infectious Diseases, Plant Biology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, multiple point mutations, machine learning algorithms, bovine enterokinase variants, achieve improved prediction, protein variant function, computational protein science, provide predictive insights, protein dynamics descriptors, sequence information alone, protein structure, protein functionality, structure information, predictive capabilities, study highlights, peptide sequence, industrial contexts, fold improvement, dynamic data
الإتاحة: https://doi.org/10.1021/acs.jcim.3c00999.s001Test
https://figshare.com/articles/journal_contribution/Machine_Learning_Integrating_Protein_Structure_Sequence_and_Dynamics_to_Predict_the_Enzyme_Activity_of_Bovine_Enterokinase_Variants/25267280Test -
2دورية أكاديمية
المؤلفون: Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A. Dalby, Duygu Dikicioglu
مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Biotechnology, Cancer, Infectious Diseases, Plant Biology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, multiple point mutations, machine learning algorithms, bovine enterokinase variants, achieve improved prediction, protein variant function, computational protein science, provide predictive insights, protein dynamics descriptors, sequence information alone, protein structure, protein functionality, structure information, predictive capabilities, study highlights, peptide sequence, industrial contexts, fold improvement, dynamic data
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3دورية أكاديمية
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
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4دورية أكاديمية
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
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5صورة
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
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6صورة
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
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7صورة
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
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8
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
العلاقة: https://figshare.com/articles/dataset/Overall_eVIP2_outputs_for_i_ARAF_i_variants_/14902718Test
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9صورة
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells
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10صورة
المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells