المؤلفون: Caswell, Deborah R, Gui, Philippe, Mayekar, Manasi K, Law, Emily K, Pich, Oriol, Bailey, Chris, Boumelha, Jesse, Kerr, D Lucas, Blakely, Collin M, Manabe, Tadashi, Martinez-Ruiz, Carlos, Bakker, Bjorn, De Dios Palomino Villcas, Juan, I. Vokes, Natalie, Dietzen, Michelle, Angelova, Mihaela, Gini, Beatrice, Tamaki, Whitney, Allegakoen, Paul, Wu, Wei, Humpton, Timothy J, Hill, William, Tomaschko, Mona, Lu, Wei-Ting, Haderk, Franziska, Al Bakir, Maise, Nagano, Ai, Gimeno-Valiente, Francisco, de Carné Trécesson, Sophie, Vendramin, Roberto, Barbè, Vittorio, Mugabo, Miriam, Weeden, Clare E, Rowan, Andrew, McCoach, Caroline E, Almeida, Bruna, Green, Mary, Gomez, Carlos, Nanjo, Shigeki, Barbosa, Dora, Moore, Chris, Przewrocka, Joanna, Black, James RM, Grönroos, Eva, Suarez-Bonnet, Alejandro, Priestnall, Simon L, Zverev, Caroline, Lighterness, Scott, Cormack, James, Olivas, Victor, Cech, Lauren, Andrews, Trisha, Rule, Brandon, Jiao, Yuwei, Zhang, Xinzhu, Ashford, Paul, Durfee, Cameron, Venkatesan, Subramanian, Temiz, Nuri Alpay, Tan, Lisa, Larson, Lindsay K, Argyris, Prokopios P, Brown, William L, Yu, Elizabeth A, Rotow, Julia K, Guha, Udayan, Roper, Nitin, Yu, Johnny, Vogel, Rachel I, Thomas, Nicholas J, Marra, Antonio, Selenica, Pier, Yu, Helena, Bakhoum, Samuel F, Chew, Su Kit, Reis-Filho, Jorge S, Jamal-Hanjani, Mariam, Vousden, Karen H, McGranahan, Nicholas, Van Allen, Eliezer M, Kanu, Nnennaya, Harris, Reuben S, Downward, Julian, Bivona, Trever G, Swanton, Charles

المصدر: Nature Genetics. 56(1)

مصطلحات موضوعية: Agricultural, Veterinary and Food Sciences, Biological Sciences, Bioinformatics and Computational Biology, Genetics, Agricultural Biotechnology, Lung Cancer, Lung, Cancer, Clinical Research, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Humans, Animals, Mice, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Mutation, Up-Regulation, ErbB Receptors, Cytidine Deaminase, Minor Histocompatibility Antigens, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7vb2s1fwTest

المؤلفون: Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart, A, Abrams, John, M, Adam, Dieter, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad, S, Altucci, Lucia, Amelio, Ivano, Andrews, David, W, Aqeilan, Rami, I, Arama, Eli, Baehrecke, Eric, H, Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai, A, Bartek, Jiri, Bazan, Nicolas, G, Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu, J M, Bianchi, Marco, E, Blagosklonny, Mikhail, V, Blander, J. Magarian, Blandino, Giovanni, Blomgren, Klas, Borner, Christoph, Bortner, Carl, D, Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, Thomas, Damgaard, Rune Busk, Calin, George, A, Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis, Chen, Guo-Qiang, Chen, Quan, Chen, Youhai, H, Cheng, Emily, H, Chipuk, Jerry, E, Cidlowski, John, A, Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan, R, Czabotar, Peter, E, D’angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted, M, Dawson, Valina, L, de Maria, Ruggero, de Strooper, Bart, Debatin, Klaus-Michael, Deberardinis, Ralph, J, Degterev, Alexei, del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott, J, Dynlacht, Brian, D, El-Deiry, Wafik, S, Elrod, John, W, Engeland, Kurt, Fimia, Gian Maria, Galassi, Claudia, Ganini, Carlo, Garcia-Saez, Ana, J, Garg, Abhishek, D, Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas, R, Greene, Lloyd, A, Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J. Marie, Haupt, Ygal, He, Sudan, Heery, David, M, Hengartner, Michael, O, Hetz, Claudio, Hildeman, David, A, Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp, J, Kanneganti, Thirumala-Devi, Karin, Michael, Kashkar, Hamid, Kaufmann, Thomas, Kelly, Gemma, L, Kepp, Oliver, Kimchi, Adi, Kitsis, Richard, N, Klionsky, Daniel, J, Kluck, Ruth, Krysko, Dmitri, V, Kulms, Dagmar, Kumar, Sharad, Lavandero, Sergio, Lavrik, Inna, N, Lemasters, John, J, Liccardi, Gianmaria, Linkermann, Andreas, Lipton, Stuart, A, Lockshin, Richard, A, López-Otín, Carlos, Luedde, Tom, Macfarlane, Marion, Madeo, Frank, Malorni, Walter, Manic, Gwenola, Mantovani, Roberto, Marchi, Saverio, Marine, Jean-Christophe, Martin, Seamus, J, Martinou, Jean-Claude, Mastroberardino, Pier, G, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Gerry, Melino, Sonia, Miao, Edward, A, Moll, Ute, M, Muñoz-Pinedo, Cristina, Murphy, Daniel, J, Niklison-Chirou, Maria Victoria, Novelli, Flavia, Núñez, Gabriel, Oberst, Andrew, Ofengeim, Dimitry, Opferman, Joseph, T, Oren, Moshe, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef, M, Pentimalli, Francesca, Pereira, David, M, Pervaiz, Shazib, Peter, Marcus, E, Pinton, Paolo, Porta, Giovanni, Prehn, Jochen, H M, Puthalakath, Hamsa, Rabinovich, Gabriel, A, Rajalingam, Krishnaraj, Ravichandran, Kodi, S, Rehm, Markus, Ricci, Jean-Ehrland, Rizzuto, Rosario, Robinson, Nirmal, Rodrigues, Cecilia, M P, Rotblat, Barak, Rothlin, Carla, V, Rubinsztein, David, C, Rudel, Thomas, Rufini, Alessandro, Ryan, Kevin, M, Sarosiek, Kristopher, A, Sawa, Akira, Sayan, Emre, Schroder, Kate, Scorrano, Luca, Sesti, Federico, Shao, Feng, Shi, Yufang, Sica, Giuseppe, S, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stephanou, Anastasis, Stockwell, Brent, R, Strapazzon, Flavie, Strasser, Andreas, Sun, Liming, Sun, Erwei, Sun, Qiang, Szabadkai, Gyorgy, Tait, Stephen, W G, Tang, Daolin, Tavernarakis, Nektarios, Troy, Carol, M, Turk, Boris, Urbano, Nicoletta, Vandenabeele, Peter, Vanden Berghe, Tom, Vander Heiden, Matthew, G, Vanderluit, Jacqueline, L, Verkhratsky, Alexei, Villunger, Andreas, von Karstedt, Silvia, Voss, Anne, K, Vousden, Karen, H, Vucic, Domagoj, Vuri, Daniela, Wagner, Erwin, F, Walczak, Henning, Wallach, David, Wang, Ruoning, Wang, Ying, Weber, Achim, Wood, Will, Yamazaki, Takahiro, Yang, Huang-Tian, Zakeri, Zahra, Zawacka-Pankau, Joanna, E, Zhang, Lin, Zhang, Haibing, Zhivotovsky, Boris, Zhou, Wenzhao, Piacentini, Mauro, Kroemer, Guido, Galluzzi, Lorenzo

المساهمون: Institut Gustave Roussy (IGR), Métabolisme, Cancer et Immunité (CRC - UMR_S 1138), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Cancer Research and Personalized Medicine - CARPEM Paris (SIRIC CARPEM), Hôpital Européen Georges Pompidou APHP (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut national du cancer (INCa)-Université Paris Cité (UPCité), ANR-21-ESRE-0028,ONCO-PHENO-SCREEN,Next-generation phenotypic screening for oncological applications(2021)

المصدر: ISSN: 1350-9047.

مصطلحات موضوعية: BAX, BCL2, cancer, death receptors, ischemia, mitochondrial outer membrane permeabilization, stroke, [SDV]Life Sciences [q-bio]

العلاقة: hal-04596448; https://hal.science/hal-04596448Test; https://hal.science/hal-04596448/documentTest; https://hal.science/hal-04596448/file/37100955.pdfTest

الإتاحة: https://doi.org/10.1038/s41418-023-01153-wTest
https://hal.science/hal-04596448Test
https://hal.science/hal-04596448/documentTest
https://hal.science/hal-04596448/file/37100955.pdfTest

المؤلفون: Tucci, Paola, Agostini, Massimiliano, Grespi, Francesca, Markert, Elke K., Terrinoni, Alessandro, Vousden, Karen H., Muller, Patricia A. J., Dötsch, Volker, Kehrloesser, Sebastian, Sayan, Berna S., Giaccone, Giuseppe, Lowe, Scott W., Takahashi, Nozomi, Vandenabeele, Peter, Knight, Richard A., Levine, Arnold J., Melino, Gerry

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2012 Sep . 109(38), 15312-15317.

الوصول الحر: https://www.jstor.org/stable/41706401Test

المؤلفون: Vousden, Karen H.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2010 Apr . 107(16), 7117-7118.

الوصول الحر: https://www.jstor.org/stable/25665316Test

المؤلفون: O’Prey, Jim, Crighton, Diane, Martin, Angel G., Vousden, Karen H., Fearnhead, Howard O., Ryan, Kevin M.

مصطلحات موضوعية: p53, nf kappa b, apoptosis, noxa, p53aip1, cancer, cell death, ribonucleotide reductase gene, programmed cell-death, induced apoptosis, p53-dependent apoptosis, DNA-damage, potential mediator, cycle checkpoint, cancer-therapy, oncogenic ras

العلاقة: Cell Cycle; O’Prey, Jim; Crighton, Diane; Martin, Angel G. Vousden, Karen H.; Fearnhead, Howard O.; Ryan, Kevin M. (2010). P53-mediated induction of noxa and p53aip1 requires nfκb. Cell Cycle 9 (5), 947-952; 1538-4101,1551-4005; http://hdl.handle.net/10379/13297Test

الإتاحة: https://doi.org/10.4161/cc.9.5.10872Test
http://hdl.handle.net/10379/13297Test

المؤلفون: Bernards, René, Jaffee, Elizabeth, Joyce, Johanna A, Lowe, Scott W, Mardis, Elaine R, Morrison, Sean J, Polyak, Kornelia, Sears, Cynthia L, Vousden, Karen H, Zhang, Zemin

مصطلحات موضوعية: cancer, diseases & disorders, neoplasms, perspective

العلاقة: Bernards, René, Jaffee, Elizabeth, Joyce, Johanna A, Lowe, Scott W, Mardis, Elaine R, Morrison, Sean J, Polyak, Kornelia, Sears, Cynthia L, Vousden, Karen H, Zhang, Zemin (January 2020) A roadmap for the next decade in cancer research. Nature Cancer, 1 (1). pp. 12-17. ISSN 2662-1347

الإتاحة: https://doi.org/10.1038/s43018-019-0015-9Test
https://repository.cshl.edu/id/eprint/40596Test/
https://www.ncbi.nlm.nih.gov/pubmed/35121845Test

المؤلفون: Tajan, Mylène¹ (AUTHOR), Vousden, Karen H.¹ (AUTHOR) karen.vousden@crick.ac.uk

المصدر: Cancer Cell. Jun2020, Vol. 37 Issue 6, p767-785. 19p.

مصطلحات موضوعية: *CANCER treatment, *GENETICS, *CANCER

المؤلفون: Humpton, Timothy, Vousden, Karen H

المصدر: Journal of Molecular Cell Biology; Jul2019, Vol. 11 Issue 7, p610-614, 5p

المؤلفون: Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnes C. L., Maddocks, Oliver D. K., Chokkathukalam, Achuthanunni, Coyle, Joseph E., Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O'Reilly, Marc, Gottlieb, Eyal

المصدر: Chaneton , B , Hillmann , P , Zheng , L , Martin , A C L , Maddocks , O D K , Chokkathukalam , A , Coyle , J E , Jankevics , A , Holding , F P , Vousden , K H , Frezza , C , O'Reilly , M & Gottlieb , E 2012 , ' Serine is a natural ligand and allosteric activator of pyruvate kinase M2 ' , Nature , vol. 491 , no. 7424 , pp. 458-462.e2 . https://doi.org/10.1038/nature11540Test

مصطلحات موضوعية: MASS-SPECTROMETRY DATA, X-RAY DATA, TUMOR-GROWTH, CANCER, CRYSTALLOGRAPHY, CONTRIBUTES, GLYCOLYSIS, METABOLISM, PATHWAY, QUALITY

العلاقة: https://research.rug.nl/en/publications/29b933b2-75bc-4d42-a74a-533ac6f1a41bTest

الإتاحة: https://doi.org/10.1038/nature11540Test
https://hdl.handle.net/11370/29b933b2-75bc-4d42-a74a-533ac6f1a41bTest
https://research.rug.nl/en/publications/29b933b2-75bc-4d42-a74a-533ac6f1a41bTest

المؤلفون: Hock, Andreas K., Lee, Pearl, Maddocks, Oliver D. K., Mason, Susan M., Blyth, Karen, Vousden, Karen H.

المصدر: Cell Cycle; 1/15/2014, Vol. 13 Issue 2, p220-226, 7p