Investigators at Johns Hopkins University Report Findings in Kidney Cancer ("oncocytoid Renal Cell Carcinomas After Neuroblastoma" Represent Tsc-mutated Eosinophilic Solid and Cystic Renal Cell Carcinomas: Association With Prior Childhood...).

التفاصيل البيبلوغرافية
العنوان: Investigators at Johns Hopkins University Report Findings in Kidney Cancer ("oncocytoid Renal Cell Carcinomas After Neuroblastoma" Represent Tsc-mutated Eosinophilic Solid and Cystic Renal Cell Carcinomas: Association With Prior Childhood...).
المصدر: Drug Week; 1/5/2024, p418-418, 1p
مصطلحات موضوعية: RENAL cell carcinoma, RENAL cancer, NEUROBLASTOMA, CHILDHOOD cancer, MTOR inhibitors
مصطلحات جغرافية: BALTIMORE (Md.)
الشركة/الكيان: JOHNS Hopkins University
مستخلص: A study conducted at Johns Hopkins University in Baltimore, Maryland, explores the concept of oncocytoid renal cell carcinoma in patients who have survived neuroblastoma. The study confirms that oncocytoid renal cell carcinomas after childhood cancer represent eosinophilic solid and cystic renal cell carcinomas (ESC RCC) and are often multifocal. The researchers found that these neoplasms respond well to MTOR inhibitor therapy, eliminating the need for further surgery. The study suggests that MTOR-targeted therapy is an effective treatment option for patients with oncocytoid renal cell carcinomas after neuroblastoma, allowing for the preservation of functional nephrons. [Extracted from the article]
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قاعدة البيانات: Complementary Index