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1دورية أكاديمية
المؤلفون: Davoodi-Moghaddam, Zeinab, Jafari-Raddani, Farideh, Delshad, Mahda, Pourbagheri-Sigaroodi, Atieh, Bashash, Davood
المصدر: Journal of Cancer Research & Clinical Oncology; Nov2023, Vol. 149 Issue 16, p15293-15310, 18p
مصطلحات موضوعية: CLINICAL trials, PHOSPHOINOSITIDES, PHOSPHATIDYLINOSITOL 3-kinases, MTOR inhibitors, TUMOR growth, DATA extraction
الشركة/الكيان: UNITED States. Food & Drug Administration
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2دورية أكاديمية
المؤلفون: Peng, Yan, Wang, Yuanyuan, Zhou, Cheng, Mei, Wuxuan, Zeng, Changchun
المصدر: Frontiers in Oncology; 3/24/2022, Vol. 12, p1-17, 17p
مصطلحات موضوعية: THERAPEUTICS, EPITHELIAL-mesenchymal transition, PUBLIC health, MTOR inhibitors, LIFE expectancy
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3دورية أكاديمية
المؤلفون: Eunüs S. Ali, Kangkana Mitra, Shamima Akter, Sarker Ramproshad, Banani Mondal, Ishaq Khan, Muhammad Torequl Islam, Javad Sharifi‐Rad, Daniela Călina, William C. Cho
مصطلحات موضوعية: mTOR Signaling in Growth and Disease, Molecular Biology, Biochemistry, Genetics and Molecular Biology, Life Sciences, Role of Pim Oncogenes in Tumorigenesis, Pathology and Forensic Medicine, Medicine, Health Sciences, Polyamines and Biogenic Amines in Biology and Health, PI3K/AKT pathway, mTOR, Cancer, rapamycin, PI3K/AKT/mTOR pathway, Autophagy, Sirolimus, Cancer research, Protein kinase B, Discovery and development of mTOR inhibitors, RPTOR, Mechanistic target of rapamycin, Signal transduction, Bioinformatics, FOS Computer and information sciences, Pharmacology, Biology, Computational biology, Apoptosis, Cell biology, Internal medicine
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4دورية أكاديمية
المؤلفون: Eskander, Ramez N, Tewari, Krishnansu S
المصدر: Expert Review of Clinical Pharmacology. 7(6)
مصطلحات موضوعية: Reproductive Medicine, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cervical Cancer, Uterine Cancer, Clinical Trials and Supportive Activities, Clinical Research, Cancer, Biotechnology, Rare Diseases, Animals, Antineoplastic Agents, Clinical Trials, Phase II as Topic, Drug Design, Female, Genital Neoplasms, Female, Humans, Neoplasm Recurrence, Local, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Proteins c-akt, TOR Serine-Threonine Kinases, cervical cancer, clear cell ovarian cancer, endometrial cancer, mTOR inhibitors, PI3K/AKT/mTOR pathway, PTEN, Pharmacology and Pharmaceutical Sciences, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/01p8v6nvTest
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المؤلفون: Kevin Lou, Ziyang Zhang, Kevan M. Shokat, Xujun Luo, William A. Weiss, Qi-Wen Fan
المصدر: Nature, vol 609, iss 7928
مصطلحات موضوعية: Drug, General Science & Technology, media_common.quotation_subject, Central nervous system, Tacrolimus Binding Protein 1A, Pharmacology, Ligands, Rare Diseases, Drug Therapy, medicine, Humans, Adverse effect, PI3K/AKT/mTOR pathway, media_common, Cancer, Sirolimus, Multidisciplinary, Kinase, business.industry, TOR Serine-Threonine Kinases, Neurosciences, Brain, MTOR Inhibitors, Ligand (biochemistry), medicine.disease, Xenograft Model Antitumor Assays, Brain Disorders, Brain Cancer, medicine.anatomical_structure, FKBP, Orphan Drug, 5.1 Pharmaceuticals, Combination, Neurological, Drug Therapy, Combination, Development of treatments and therapeutic interventions, business, Glioblastoma
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d384cbe2d04023b9624254d84e3a1a69Test
https://doi.org/10.1038/s41586-022-05213-yTest -
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المؤلفون: Seyed Mohammad Abedi, Samaneh Vaseghi, Nasrin Abbasi Gharibkandi, Alireza Mardanshahi, Sajjad Molavipordanjani
المصدر: Molecular Biology Reports. 48:1-14
مصطلحات موضوعية: Cell Survival, medicine.medical_treatment, Apoptosis, Radiation Tolerance, Phosphatidylinositol 3-Kinases, Cell Line, Tumor, Neoplasms, Autophagy, Genetics, medicine, Humans, Radiosensitivity, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Cell growth, Akt/PKB signaling pathway, business.industry, TOR Serine-Threonine Kinases, Cell Cycle, Cancer, MTOR Inhibitors, General Medicine, medicine.disease, Radiation therapy, Cancer research, business, Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fdb87979d16875fbb742eee534b74bTest
https://doi.org/10.1007/s11033-021-06607-3Test -
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المؤلفون: Kerry Mansell, Nassrein Hussein, Terra Arnason, Carly Yim
المصدر: World Journal of Diabetes
مصطلحات موضوعية: Drug, mTOR inhibitors, Diabetic ketoacidosis, Cancer therapy, medicine.drug_class, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, 5-fluorouracil analogs, Review, Bioinformatics, Antimetabolite, Immune checkpoint inhibitors, Diabetes mellitus, Internal Medicine, medicine, Glucocorticoids, PI3K/AKT/mTOR pathway, media_common, business.industry, Type 2 Diabetes Mellitus, Cancer, adverse drug effects, medicine.disease, Drug class, Hyperglycemia, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c216e93e44084d30a7951ea6f6dcb1Test
http://europepmc.org/articles/PMC8311484Test -
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المؤلفون: Chiara Borsari, Matthias P. Wymann, Martina De Pascale
المصدر: Chemmedchem
مصطلحات موضوعية: mTOR inhibitors, Structural similarity, Allosteric regulation, physicochemical properties, Blood–brain barrier, Biochemistry, binding modes, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, chemical scaffolds, Drug Discovery, medicine, BBB permeability, Humans, General Pharmacology, Toxicology and Pharmaceutics, Protein Kinase Inhibitors, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, 030304 developmental biology, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Kinase, TOR Serine-Threonine Kinases, Organic Chemistry, Cancer, Minireviews, medicine.disease, Chemical space, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Molecular Medicine, Minireview
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610b11369182775aec800164fa18275dTest
https://doi.org/10.1002/cmdc.202100332Test -
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المؤلفون: Mee-Sup Yoon
المصدر: International Journal of Nanomedicine. 15:5767-5781
مصطلحات موضوعية: Mtor signaling, Cell growth, Chemistry, Organic Chemistry, Biophysics, Pharmaceutical Science, Cancer, Master regulator, Bioengineering, 02 engineering and technology, General Medicine, 010402 general chemistry, 021001 nanoscience & nanotechnology, medicine.disease, Discovery and development of mTOR inhibitors, 01 natural sciences, Enhanced bioavailability, 0104 chemical sciences, Biomaterials, Drug Discovery, Cancer research, medicine, Extracellular, 0210 nano-technology, PI3K/AKT/mTOR pathway
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::aebade610a847b6f6369ab5f9597ed9bTest
https://doi.org/10.2147/ijn.s254574Test -
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المؤلفون: Marzanna Cechowska-Pasko, Ewa Jabłońska, Wioletta Ratajczak-Wrona, Rafał Krętowski, Wioleta Justyna Omeljaniuk
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 11511, p 11511 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21مصطلحات موضوعية: GDC-0980, Cell Survival, QH301-705.5, CHOP, Article, Catalysis, Metastasis, Inorganic Chemistry, Cell Line, Tumor, medicine, Humans, Physical and Theoretical Chemistry, Biology (General), Cytotoxicity, Molecular Biology, Protein kinase B, QD1-999, Spectroscopy, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Chemistry, Brain Neoplasms, Organic Chemistry, Autophagosomes, apoptosis, glioblastoma, Cancer, General Medicine, MTOR Inhibitors, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Endoplasmic Reticulum Stress, dual PI3K/mTOR inhibitor, Computer Science Applications, Pyrimidines, Apoptosis, Cell culture, Cancer research, apitolisib, Drug Screening Assays, Antitumor, Metabolic Networks and Pathways
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2276301b12f4db2a038b16ea5030b6b3Test
https://www.mdpi.com/1422-0067/22/21/11511Test