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المصدر: Current Pharmaceutical Design. 27:942-952
مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Oncology, medicine.medical_specialty, Class I Phosphatidylinositol 3-Kinases, Colorectal cancer, medicine.disease_cause, Proto-Oncogene Proteins p21(ras), Causes of cancer, Internal medicine, Drug Discovery, Biomarkers, Tumor, medicine, Humans, In patient, EGFR inhibitors, Pharmacology, business.industry, Cancer, medicine.disease, digestive system diseases, Circulating Cell-Free DNA, Cell-free fetal DNA, Mutation, KRAS, Colorectal Neoplasms, business, Cell-Free Nucleic Acids
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93b8d787be72ab8653d8483ad2bcaedTest
https://doi.org/10.2174/1381612826666201007163116Test -
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المؤلفون: Juliet Williams, Jeffrey A. Engelman, Guizhi Yang, Matthew J. Meyer, Huai Xiang Hao, William D. Hastings, Chen Liu, Tinya Abrams, Silvia Goldoni, Hui Gao, Giordano Caponigro, Peter S. Hammerman, Hongyun Wang, Colleen Kowal, Scott Delach, Alice Loo, Hengyu Lu, Susan Moody, Matthew J. LaMarche, Ye Wang, Karrie Wong, Morvarid Mohseni, Xiamei Zhang
المصدر: Clinical Cancer Research. 27:342-354
مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Programmed Cell Death 1 Receptor, Allosteric regulation, Protein Tyrosine Phosphatase, Non-Receptor Type 11, medicine.disease_cause, Receptor tyrosine kinase, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Cell Line, Tumor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Tumor-Associated Macrophages, medicine, Animals, Humans, Immune Checkpoint Inhibitors, Protein Kinase Inhibitors, EGFR inhibitors, Tumor microenvironment, biology, Chemistry, Cyclin-Dependent Kinase 4, Cancer, Drug Synergism, Cyclin-Dependent Kinase 6, medicine.disease, Xenograft Model Antitumor Assays, ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer cell, biology.protein, Cancer research, Female, KRAS
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3c3f6b2f214726db8bd9a82f04ec4Test
https://doi.org/10.1158/1078-0432.ccr-20-2718Test -
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المؤلفون: Chengyu Wang, Yuquan Wang, Zhangxiang Zhao, Qi Dong, Liqiang Ai, Haihai Liang, Tingting Chen, Bo Chen, Yawei Li, Lishuang Qi, Mingyue Liu, Yaoyao Liu, Yunyan Gu, Shuping Zhuang
المصدر: Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4435-4446 (2021)
Computational and Structural Biotechnology Journalمصطلحات موضوعية: Veliparib, Biophysics, Resistant biomarkers, Synthetic lethality, Biology, Biochemistry, Sensitive biomarkers, chemistry.chemical_compound, PARP1, Structural Biology, Genetics, medicine, PARP inhibitors, ComputingMethodologies_COMPUTERGRAPHICS, EGFR inhibitors, Genetic interactions, Cancer, medicine.disease, Computer Science Applications, chemistry, Pharmacogenomics, PARP inhibitor, Mutation, Cancer research, Erlotinib, TP248.13-248.65, Research Article, medicine.drug, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd5dd1ddf75a3287aed53de1a0263b5Test
http://www.sciencedirect.com/science/article/pii/S200103702100338XTest -
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المؤلفون: Kulbhushan Tikoo, Sandeep Singh, Nisha Sharma, Sajal Biswas, Gaurav Joshi, Raj Kumar, Tashvinder Singh, Manvendra Kumar, Zahid Rafiq Bhat, Sahil Arora
المصدر: Molecules
Volume 26
Issue 5
Molecules, Vol 26, Iss 1490, p 1490 (2021)مصطلحات موضوعية: Lung Neoplasms, Pharmaceutical Science, 01 natural sciences, Analytical Chemistry, chemistry.chemical_compound, T790M, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Epidermal growth factor receptor, biology, Imidazoles, Gefitinib, ErbB Receptors, Molecular Docking Simulation, imidazo[1,2-a]quinoxaline, Chemistry (miscellaneous), Molecular Medicine, Erlotinib, medicine.drug, Antineoplastic Agents, mutant EGFR inhibitors, Article, lcsh:QD241-441, Erlotinib Hydrochloride, Inhibitory Concentration 50, Structure-Activity Relationship, anticancer agents, Quinoxaline, lcsh:Organic chemistry, Cell Line, Tumor, Quinoxalines, medicine, Humans, Physical and Theoretical Chemistry, Lung cancer, Protein Kinase Inhibitors, Cell Proliferation, 010405 organic chemistry, Organic Chemistry, non-covalent EGFR inhibitors, Wild type, Cancer, medicine.disease, 0104 chemical sciences, respiratory tract diseases, 010404 medicinal & biomolecular chemistry, chemistry, A549 Cells, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, Drug Screening Assays, Antitumor
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3beb00e5f569c499c49be90ff8547Test
http://europepmc.org/articles/PMC7967119Test -
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المؤلفون: Ines Pulido, Javier Alcácer, Javier Alcácer Fernández-Coronado, Julian Carretero, José M. Galbis-Caravajal, Kwok-Kin Wong, Patricia E. Simms, Jeffrey H. Becker, Paloma Martín-Martorell, Rutu Gandhi, Margaret Soucheray, Miguel Aupi, Aránzazu Lafuente-Sanchis, Amelia Insa, Agustín Lahoz, Ashley Hess, Fatima Al-Shahrour, Camilla L. Christensen, Michael P. Kahle, Yandi Gao, Jeffrey A. Borgia, Oscar Juan, Maria L. Rodriguez, Hajime Asahina, Antonio Cremades, Eiki Kikuchi, Pasi A. Jänne, Takeshi Shimamura
المصدر: CANCER RESEARCH
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Cancer research, vol 79, iss 17
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVAمصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Lung Neoplasms, Drug Resistance, Drug resistance, Transgenic, Mice, Chemokine receptor, 0302 clinical medicine, Neoplasms, Carcinoma, Non-Small-Cell Lung, Receptors, Medicine, Non-Small-Cell Lung, CXCR, Receptor, Lung, beta-Arrestins, Cancer, EGFR inhibitors, Tumor, Kinase, Lung Cancer, ErbB Receptors, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Development of treatments and therapeutic interventions, Tyrosine kinase, Epithelial-Mesenchymal Transition, MAP Kinase Signaling System, Oncology and Carcinogenesis, Mice, Transgenic, Article, Cell Line, Experimental, 03 medical and health sciences, Clinical Research, Cell Line, Tumor, Animals, Humans, Oncology & Carcinogenesis, Protein Kinase Inhibitors, Receptors, CXCR, business.industry, Carcinoma, Neoplasms, Experimental, respiratory tract diseases, 030104 developmental biology, Protein kinase domain, Drug Resistance, Neoplasm, Mutation, Cancer research, Neoplasm, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c52d2f5e680641900c05fb94312301Test
https://doi.org/10.1158/0008-5472.can-19-0024Test -
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المؤلفون: Yasmin A. Kadry, Eric S. Witze, Jia-Ying Lee
المصدر: Open Biology, Vol 11, Iss 10 (2021)
Open Biologyمصطلحات موضوعية: Lung Neoplasms, QH301-705.5, Lipoylation, EGFR, Immunology, Adenocarcinoma of Lung, Review, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, lung, Proto-Oncogene Proteins p21(ras), Mice, Protein Domains, Palmitoylation, medicine, Animals, Humans, cancer, palmitoylation, Epidermal growth factor receptor, signalling, Biology (General), Review Articles, EGFR inhibitors, Egfr signalling, biology, General Neuroscience, Cancer, medicine.disease, ErbB Receptors, Gene Expression Regulation, Neoplastic, Signalling, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, Carcinogenesis, Acyltransferases, Signal Transduction, DHHC20
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a085d6bc23140dc47b5846ea0aa44fTest
https://royalsocietypublishing.org/doi/10.1098/rsob.210033Test -
7Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
المؤلفون: Soma Ghosh, Diana Drago-Garcia, Tomer-Meir Salame, Donatella Romaniello, Ilaria Marrocco, Itay Vaknin, Roni Oren, Nishanth Belugali Nataraj, Moshit Lindzen, Mary Luz Uribe, Yosef Yarden, Raya Eilam
المساهمون: Marrocco I, Romaniello D, Vaknin I, Drago-Garcia D, Oren R, Uribe ML, Belugali Nataraj N, Ghosh S, Eilam R, Salame TM, Lindzen M, Yarden Y.
المصدر: EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
EMBO Molecular Medicineمصطلحات موضوعية: 0301 basic medicine, Medicine (General), Lung Neoplasms, Respiratory System, Antibiotics, EGFR TKI, mAbs, QH426-470, NSCLC, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Organic Chemicals, Cancer, EGFR inhibitors, media_common, Settore BIO/11 - BIOLOGIA MOLECOLARE, biology, Articles, EGFR TKIs, 3. Good health, ErbB Receptors, Molecular Medicine, Antibody, Tyrosine kinase, Drug, medicine.drug_class, media_common.quotation_subject, Article, resistance, 03 medical and health sciences, R5-920, first-line therapy, medicine, Genetics, Humans, Lung cancer, Protein Kinase Inhibitors, business.industry, first‐line therapy, medicine.disease, respiratory tract diseases, 030104 developmental biology, Drug Resistance, Neoplasm, Egfr mutation, Mutation, biology.protein, Cancer research, FOXM1, business, 030217 neurology & neurosurgery
وصف الملف: ELETTRONICO
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9f29fc029bd077e7fd5e975da24951Test
https://doaj.org/article/f40e6d84396d426eb6294535a2d589baTest -
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المؤلفون: Roberto Giovannoni, Diego Cortinovis, Sara Bonomo, Silvano Bosari, Annamaria Cialdella, Irene Forno, Leonarda Ianzano, Gian-Luca Ferri, Emanuela Grassilli, Federica Brena, Maria Grazia Cerrito, Valentina Vaira, F. Damarco, Ennio Tasciotti, Silve Vicent, Federica Giordano, Marialuisa Lavitrano, Joyce Goedmakers
المساهمون: Giordano, F, Vaira, V, Cortinovis, D, Bonomo, S, Goedmakers, J, Brena, F, Cialdella, A, Ianzano, L, Forno, I, Cerrito, M, Giovannoni, R, Ferri, G, Tasciotti, E, Vicent, S, Damarco, F, Bosari, S, Lavitrano, M, Grassilli, E
المصدر: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Dadun. Depósito Académico Digital de la Universidad de Navarra
instnameمصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, Gene Expression, medicine.disease_cause, NSCLC, Targeted therapy, Mice, 0302 clinical medicine, Agammaglobulinaemia Tyrosine Kinase, Protein Isoforms, EGFR inhibitors, BTK inhibitor, Drug Synergism, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, EGFR inhibitor, Pemetrexed, Oncology, 030220 oncology & carcinogenesis, Erlotinib, KRAS, Ciencias de la Salud::Oncología [Materias Investigacion], medicine.drug, Signal Transduction, Cell Survival, EGFR, Adenocarcinoma of Lung, Antineoplastic Agents, lcsh:RC254-282, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Gefitinib, Cell Line, Tumor, medicine, Biomarkers, Tumor, Animals, Humans, Chemotherapy, Lung cancer, Protein Kinase Inhibitors, Cell Proliferation, Neoplasm Staging, business.industry, Research, Cancer, medicine.disease, respiratory tract diseases, BTK inhibitors, 030104 developmental biology, Drug resistance, p65BTK, Mutation, Cancer research, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42acbafac259cd31fb6a1e937e74b5dTest
http://link.springer.com/article/10.1186/s13046-019-1199-7Test -
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المؤلفون: Alice T. Shaw, Jochen K. Lennerz, Mari Mino-Kenudson, Hideko Isozaki, Subba R. Digumarthy, Inga T. Lennes, Rebecca J. Nagy, Corinne Clifford, Aaron N. Hata, Jessica J. Lin, Lecia V. Sequist, Mandeep Banwait, Amanda K. Riley, Dora Dias-Santagata, Justin F. Gainor, Zofia Piotrowska, Sai-Hong Ignatius Ou, Varuna Nangia, Viola W. Zhu, Rebecca S. Heist, Richard B. Lanman, Nicolas Marcoux, Wenjia Su, A. John Iafrate, Satoshi Yoda, Erica Evans, Beni B. Wolf
المصدر: Cancer Discovery. 8:1529-1539
مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, endocrine system diseases, Cabozantinib, Drug resistance, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, T790M, 0302 clinical medicine, medicine, Carcinoma, Osimertinib, neoplasms, EGFR inhibitors, Mutation, business.industry, Cancer, medicine.disease, respiratory tract diseases, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::84d9ca6ab728fc4d27e4597dd3b54fe0Test
https://doi.org/10.1158/2159-8290.cd-18-1022Test -
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المساهمون: School of Biological Sciences, Bioinformatics Institute, A*STAR
المصدر: Journal of Chemical Information and Modeling. 59:309-315
مصطلحات موضوعية: Protein Conformation, General Chemical Engineering, Afatinib, Mutant, Single-nucleotide polymorphism, Molecular Dynamics Simulation, Library and Information Sciences, medicine.disease_cause, Polymorphism, Single Nucleotide, 01 natural sciences, Exon, Polymorphism (computer science), 0103 physical sciences, medicine, Data Mining, Humans, Free Energy, EGFR inhibitors, Mutation, 010304 chemical physics, Chemistry, Peptides And Proteins, Biological sciences [Science], Cancer, General Chemistry, medicine.disease, 0104 chemical sciences, Computer Science Applications, ErbB Receptors, 010404 medicinal & biomolecular chemistry, Cancer research, Thermodynamics, Protein Binding, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74675fd556a3336b35b86194bd6d822Test
https://doi.org/10.1021/acs.jcim.8b00491Test
