Meningococcal Disease in Catalonia 1 Year after Mass Vaccination Campaign with Meningococcal Group C Polysaccharide Vaccine
| العنوان: | Meningococcal Disease in Catalonia 1 Year after Mass Vaccination Campaign with Meningococcal Group C Polysaccharide Vaccine |
|---|---|
| المؤلفون: | Sofia Minguell, Julio A. Vázquez, Helena Pañella, A. Martínez, Angela Domínguez, Pere Godoy, Neus Cardeñosa, Neus Camps, Josep Álvarez |
| المصدر: | Infection. 31:392-397 |
| بيانات النشر: | Springer Science and Business Media LLC, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Adult, Male, Microbiology (medical), Pediatrics, medicine.medical_specialty, Time Factors, Adolescent, Meningococcal Vaccines, Meningitis, Meningococcal, medicine.disease_cause, Meningococcal disease, Polysaccharide Vaccine, Mass Vaccination, Risk Assessment, Age Distribution, Epidemiology, Case fatality rate, Prevalence, medicine, Humans, Serologic Tests, Registries, Sex Distribution, Child, Immunization Programs, business.industry, Neisseria meningitidis, Incidence (epidemiology), Polysaccharides, Bacterial, Infant, General Medicine, Middle Aged, medicine.disease, Meningococcal Infections, Survival Rate, Vaccination, Infectious Diseases, El Niño, Spain, Child, Preschool, Immunology, Female, business, Follow-Up Studies |
| الوصف: | Background: The aim of this study was to investigate the clinical and epidemiological characteristics of meningococcal disease in Catalonia (Spain) after vaccination with the polysaccharide vaccine. Patients and Methods: Cases were collected by the Statutory Diseases Reporting System. Results: 176 cases were reported, an overall incidence of 2.9/100,000 persons/year. 60% of cases occurred during winter and spring. The case fatality rate was 6.3%. The highest age incidence was in children under 2 years of age (48/100,000 persons/year). Comparison of the cases detected by the Statutory Diseases Reporting System with those obtained by the Microbiological Reporting System shows that meningococcal disease surveillance in Catalonia was relatively complete (95.7%), with a positive predictive value of 66.3%. 115 cases (65%) were culture-confirmed with a rate of 1.9/100,000 persons/year. 86 (75%) cases were due to Neisseria meningitidis serogroup B and 21 to serogroup C (18%). Conclusion: Although infections due to serogroup C have decreased after mass vaccination with the polysaccharide vaccine, it is likely that the number of infections will decrease further with the conjugate meningococcal group C vaccine. |
| تدمد: | 1439-0973 0300-8126 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5760df86cc48f03ac8a0153401d8ce6Test https://doi.org/10.1007/s15010-003-3121-6Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....c5760df86cc48f03ac8a0153401d8ce6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14390973 03008126 |
|---|