المؤلفون: Julie A. Jonassen, Gregory J. Pazour, Roger J. Davis, Kenley Preval, Abigail O. Smith

المصدر: PLoS Genetics
PLoS Genetics, Vol 17, Iss 12, p e1009711 (2021)

مصطلحات موضوعية: Cancer Research, Cell signaling, Physiology, medicine.medical_treatment, QH426-470, Signal transduction, urologic and male genital diseases, Kidney, Biochemistry, Epithelium, Medical Conditions, Animal Cells, Polycystic kidney disease, Medicine and Health Sciences, Post-Translational Modification, Phosphorylation, Genetics (clinical), Cystic kidney, c-jun, Signaling cascades, Animal Models, Polycystic Kidney, Autosomal Dominant, c-Jun N-terminal kinase signaling cascade, Experimental Organism Systems, Physiological Parameters, Genetic Diseases, Anatomy, Cellular Types, Research Article, Cell biology, TRPP Cation Channels, MAP Kinase Signaling System, Autosomal dominant polycystic kidney disease, Mouse Models, Research and Analysis Methods, End stage renal disease, Cystic kidney disease, Model Organisms, Polycystic Kidney Disease, Weight Loss, medicine, Genetics, Humans, Mitogen-Activated Protein Kinase 9, Mitogen-Activated Protein Kinase 8, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Dialysis, Cell Proliferation, Clinical Genetics, PKD1, business.industry, urogenital system, Body Weight, Autosomal Dominant Diseases, JNK Mitogen-Activated Protein Kinases, Biology and Life Sciences, Proteins, Kidneys, Epithelial Cells, Renal System, medicine.disease, Fibrosis, Biological Tissue, Mutation, Cancer research, Animal Studies, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b84f3446b6baa3eda5738e929eeae6Test
http://europepmc.org/articles/PMC8746764Test

المؤلفون: Jun Zhang, Roger J. Davis, Meng Li, Christopher Q. Chen, Anna Mae Diehl, Mariam Aghajan, Ying Wang, Robert Win Maw Min, Tin Aung Than, Sanda Win, Neil Kaplowitz, Yibu Chen, Manal F. Abdelmalek, Filbert W.M. Aung, Ayako Suzuki

المصدر: Journal of Clinical Investigation. 129:5278-5293

مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, medicine.medical_specialty, Programmed cell death, medicine.drug_class, Apoptosis, Mitochondria, Liver, Mitochondrial Proteins, Mice, Necrosis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Animals, Humans, RNA, Messenger, Acetaminophen, Liver injury, Gene knockdown, Messenger RNA, Cell Death, business.industry, Estrogen Receptor alpha, Membrane Proteins, General Medicine, Liver Failure, Acute, medicine.disease, Mice, Inbred C57BL, MicroRNAs, HEK293 Cells, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, 030220 oncology & carcinogenesis, Galactosamine, Mitochondrial Membranes, Hepatocytes, Female, Tumor necrosis factor alpha, Chemical and Drug Induced Liver Injury, Tumor Suppressor Protein p53, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8208d1bc47c5daa16c9d639076987bTest
https://doi.org/10.1172/jci128289Test

المؤلفون: Siobhan M. Craige, Shashi Kant, Roger J. Davis, Mark J. S. Kelly, Khanh-Van Tran, Marc R. Freeman, Heather Learnard, Kai Chen, Kasmir Ramo, John F. Keaney, Michaella M. Reif, Amada D. Caliz, Owen M. Peters

المساهمون: Human Nutrition, Foods, and Exercise

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Science, General Physics and Astronomy, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Ischemia, Mitogen-Activated Protein Kinase 10, Internal medicine, medicine, Animals, Humans, Cyclic AMP Response Element-Binding Protein, Muscle, Skeletal, lcsh:Science, Transcription factor, Early Growth Response Protein 1, Neurons, Multidisciplinary, PDGFB, biology, Kinase, business.industry, Forkhead Box Protein O3, General Chemistry, Hindlimb, 3. Good health, Mice, Inbred C57BL, Vascular endothelial growth factor A, Mechanisms of disease, 030104 developmental biology, Endocrinology, Regional Blood Flow, Peripheral vascular disease, FOXO3, biology.protein, lcsh:Q, Signal transduction, business, CREB1, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c7111ffcfd559c08ac473f08f44bbaTest
https://doaj.org/article/c85d0f19e33747f1a03502a4c952220bTest

المؤلفون: Timothy D. Calamaras, Joseph C. McCarthy, Peiwen Liu, Weiyu Lin, Iris Z. Jaffe, Seung Kyum Kim, Guang-rong Wang, Kelly Tam, Richard H. Karas, Robert M. Blanton, Suchita Pande, Jonathan I. Aguirre, Mark Aronovitz, Angela L. McLaughlin, Roger J. Davis, Daniel A. Richards, Paulina Baca, Gregory L. Martin, Robert A.U. Baumgartner

المصدر: JCI Insight

مصطلحات موضوعية: Male, Cardiac function curve, Pyridines, Vasodilator Agents, Myocytes, Smooth Muscle, Cyclic nucleotides, Cardiology, Blood Pressure, Heart failure, Pharmacology, Muscle, Smooth, Vascular, Sildenafil Citrate, Mice, Ventricular Dysfunction, Left, Vascular Stiffness, medicine, Animals, Humans, Pyrroles, Phosphorylation, Kinase activity, Protein kinase A, Protein Kinase Inhibitors, Aorta, Cyclic GMP-Dependent Protein Kinase Type I, Mice, Knockout, Pressure overload, Kinase, business.industry, General Medicine, MAP Kinase Kinase Kinases, medicine.disease, HEK293 Cells, Blood pressure, medicine.anatomical_structure, Ventricle, Hypertension, Pyrazoles, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14251414ed0b6af76dbfa68dc1d3d62Test
https://doi.org/10.1172/jci.insight.149075Test

المؤلفون: Yvonne C. Lee, Ana Paula Arruda, Eva Tsaousidou, Emre Guney, Gökhan S. Hotamisligil, Gunes Parlakgul, Han Ms, Cagampan E, Greene L, Roger J. Davis, Karen Inouye, Min N

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Insulin, medicine.medical_treatment, Adipose tissue, Inflammation, Inositol trisphosphate receptor, medicine.disease, chemistry.chemical_compound, Insulin resistance, Endocrinology, chemistry, Internal medicine, Diabetes mellitus, Adipocyte, medicine, medicine.symptom, business, Homeostasis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::18dd7e00f0a10479045b2c260211fa11Test
https://doi.org/10.1101/2020.10.28.360008Test

المؤلفون: J Hayback, Mohamed, Francisco Javier Cubero, Christian Trautwein, Mark V. Boekschoten, Roger J. Davis

المصدر: Zeitschrift für Gastroenterologie.

مصطلحات موضوعية: Liver injury, Pathology, medicine.medical_specialty, Fibrosis, business.industry, Chronic cholestasis, medicine, medicine.disease, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::814fe94186041ca633c5340e1ae68332Test
https://doi.org/10.1055/s-0039-3402128Test

المؤلفون: Kyathanahalli S. Janardhan, Cynthia J. Willson, Chad J. Creighton, Roger J. Davis, Patricia Castro, Tianyuan Wang, Madhumita Ray, Francesco J. DeMayo, Jian Liu, San-Pin Wu, Sung-Nam Cho, Jian-Liang Li, Michael Ittmann

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, Science, Cell, General Physics and Astronomy, 02 engineering and technology, General Biochemistry, Genetics and Molecular Biology, Fight-or-flight response, 03 medical and health sciences, In vivo, medicine, skin and connective tissue diseases, lcsh:Science, PI3K/AKT/mTOR pathway, Multidisciplinary, Lung, business.industry, Lung squamous cell carcinoma, Cancer, General Chemistry, 021001 nanoscience & nanotechnology, medicine.disease, Head and neck squamous-cell carcinoma, 3. Good health, enzymes and coenzymes (carbohydrates), 030104 developmental biology, medicine.anatomical_structure, Cancer research, lcsh:Q, biological phenomena, cell phenomena, and immunity, 0210 nano-technology, business, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3079a0a80ffd04586c0d07c76c4d8a2cTest
https://doi.org/10.1038/s41467-019-09843-1Test

المؤلفون: Christine Lim, Jonah Cohen, Manuel Hidalgo, Ling Huang, Benjamin L. Schlechter, Roger J. Davis, Mary Linton B. Peters, Senthil K. Muthuswamy, Bruno Bockorny, Mark P. Callery, Joseph Elan Grossman, Supraja Narasimhan, Leo L. Tsai, Douglas K. Pleskow, Catherine Conahan, Dipikaa Akshinthala, Sofia Perea, Robert J. Besaw, Mandeep S. Sawhney, Raul S. Gonzalez, Tyler M. Berzin, Andrea J. Bullock, Lakshmi B. Muthuswamy, Martin P. Smith, Tara S. Kent

المصدر: Tumor Biology

مصطلحات موضوعية: 0301 basic medicine, Drug, Oncology, Cancer Research, medicine.medical_specialty, media_common.quotation_subject, Disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Pancreatic cancer, Ascites, Organoid, Medicine, Lymph node, media_common, business.industry, Cancer, medicine.disease, 3. Good health, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66e17f181ca5786392c6b3ba9de76c9Test
https://doi.org/10.1158/1538-7445.am2020-ct119Test

المؤلفون: Dario C. Altieri, Peter A. McCue, Qin Liu, Dmitry I. Gabrilovich, Roger J. Davis, Aejaz Sayeed, Alexander Duffy, Huimin Lu, Lucia R. Languino, Ulrich Rodeck, David Deming, Adam P. Dicker

المصدر: Oncotarget

مصطلحات موضوعية: Male, 0301 basic medicine, Mice, Transgenic, Adenocarcinoma, urologic and male genital diseases, medicine.disease_cause, Receptor, IGF Type 1, Metastasis, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Growth factor receptor, Cell Line, Tumor, medicine, Animals, Humans, Phosphorylation, insulin-like growth factor receptor, Cell Proliferation, Anthracenes, Tumor microenvironment, FAK, business.industry, Gene Expression Profiling, Integrin beta1, JNK Mitogen-Activated Protein Kinases, TRAMP mice, Prostatic Neoplasms, prostate cancer, medicine.disease, Combined Modality Therapy, Molecular medicine, β1 integrins, Tumor Burden, 3. Good health, 030104 developmental biology, Oncology, Focal Adhesion Protein-Tyrosine Kinases, 030220 oncology & carcinogenesis, Immunology, Cancer research, Radiation Dose Hypofractionation, business, Carcinogenesis, Priority Research Paper, Tramp

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0827a8465b123aea233522e4419bbf15Test
https://doi.org/10.18632/oncotarget.10522Test

المؤلفون: Roger J. Davis, Myoung Sook Han, Tamera Barrett, Michael A. Brehm

المصدر: Cell Reports, Vol 15, Iss 1, Pp 19-26 (2016)

مصطلحات موضوعية: Male, 0301 basic medicine, Carcinoma, Hepatocellular, Myeloid, MAP Kinase Kinase 4, Inflammation, Article, General Biochemistry, Genetics and Molecular Biology, Hepatitis, Mice, 03 medical and health sciences, Liver disease, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Carcinoma, Animals, Myeloid Cells, lcsh:QH301-705.5, Kinase, business.industry, Liver Neoplasms, medicine.disease, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Immunology, medicine.symptom, Signal transduction, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9151e43c01748703a27ec2bed92dc37Test
https://doi.org/10.1016Test/j.celrep.2016.03.008