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المؤلفون: Ciro Abbondanza, Mariarosaria Conte, Angela Nebbioso, Vincenzo Carafa, Lucia Altucci, Gabriella Lania, Valeria Belsito Petrizzi, Francesco Iovino, Francesco Paolo Tambaro, Hendrik G. Stunnenberg, Concetta Ingenito, Isabella Pallavicini, Rosaria Benedetti, Matthias Nees, Guillermo Garcia-Manero, Joost H.A. Martens, Saverio Minucci
المساهمون: Nebbioso, Angela, Carafa, Vincenzo, Conte, Mariarosaria, Tambaro, Francesco Paolo, Abbondanza, Ciro, Martens, Joost H. A, Nees, Matthia, Benedetti, Rosaria, Pallavicini, Isabella, Minucci, Saverio, Garcia Manero, G, Iovino, Francesco, Lania, Gabriella, Ingenito, Concetta, Belsito Petrizzi, Valeria, Stunnenberg, Hendrik G, Altucci, Lucia
المصدر: Clinical cancer research
23 (2016): 2542–2555. doi:10.1158/1078-0432.CCR-15-2388
info:cnr-pdr/source/autori:Nebbioso A., Carafa V, Conte M, Tambaro FP, Abbondanza C, Martens JH, Nees M, Benedetti R, Pallavicini I, Minucci S, Garcia-Manero G, Iovino F, Lania G, Ingenito C, Belsito Petrizzi V, Stunnenberg HG, Altucci L./titolo:c-Myc modulation & acetylation is a key HDAC inhibitor target in cancer/doi:10.1158%2F1078-0432.CCR-15-2388/rivista:Clinical cancer research (Print)/anno:2016/pagina_da:2542/pagina_a:2555/intervallo_pagine:2542–2555/volume:23
Clinical Cancer Research, 23, 2542-2555
Clinical Cancer Research, 23, 10, pp. 2542-2555مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Sp1 Transcription Factor, Kruppel-Like Transcription Factors, Histone Deacetylase 1, Proto-Oncogene Proteins c-myc, TNF-Related Apoptosis-Inducing Ligand, 03 medical and health sciences, Cell Line, Tumor, Neoplasms, hemic and lymphatic diseases, medicine, Humans, Molecular Biology, Regulation of gene expression, Clinical Trials as Topic, Gene Expression Regulation, Leukemic, business.industry, Myeloid leukemia, Cancer, Acetylation, medicine.disease, c-Myc modulation, 3. Good health, Histone Deacetylase Inhibitors, Leukemia, 030104 developmental biology, Oncology, Apoptosis, Immunology, Cancer cell, Cancer research, Histone deacetylase, business, Ex vivo, Protein Binding, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9574b9aa831c211f48b337e4a785778Test
https://hdl.handle.net/2066/165880Test -
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المصدر: Statistics in Biopharmaceutical Research. 8:217-228
مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Biometrics, Computer science, Tumor spheroid, Pharmaceutical Science, Principal curves, ta3111, 01 natural sciences, Texture (geology), 010104 statistics & probability, 03 medical and health sciences, Computer vision, 0101 mathematics, Cluster analysis, Throughput (business), ta113, ta112, business.industry, ta1182, Pattern recognition, ta3122, Multicellular organism, 030104 developmental biology, Microscopic imaging, Artificial intelligence, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf245302516c24d656824227c26f5812Test
https://doi.org/10.1080/19466315.2016.1146162Test -
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المؤلفون: Hannu-Pekka Schukov, Matthias Nees, Janne Heikkilä, Malin Åkerfelt, Sean Robinson, Raija Sormunen, Neslihan Bayramoglu, Johannes Virtanen, Juho Kannala, Mika Kaakinen, Mervi Toriseva, Ville Härmä, Lauri Eklund
المساهمون: Turku Centre for Biotechnology, University of Turku-Åbo Academy University, University of Turku, Laboratoire de Biologie à Grande Échelle (BGE - UMR S1038), Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), VTT Technical Research Centre of Finland (VTT), Machine Vision Group (MVG), University of Oulu, Center for Machine Vision Research (CMV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
المصدر: Oncotarget
Oncotarget, Impact journals, 2015, 6 (30), ⟨10.18632/oncotarget.5046⟩
Oncotarget, 2015, 6 (30), ⟨10.18632/oncotarget.5046⟩
Åkerfelt, M, Bayramoglu, N, Robinson, S, Toriseva, M, Schukov, H-P, Härmä, V, Virtanen, J, Sormunen, R, Kaakinen, M, Kannala, J, Eklund, L, Heikkilä, J & Nees, M 2015, ' Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention ', Oncotarget, vol. 6, no. 30, pp. 30035-30056 . https://doi.org/10.18632/oncotarget.5046Testمصطلحات موضوعية: Male, [SDV]Life Sciences [q-bio], focal adhesion kinase (FAK), Cell Culture Techniques, Cell Communication, Prostate cancer, 0302 clinical medicine, Cell Movement, Tumor Microenvironment, ComputingMilieux_MISCELLANEOUS, 0303 health sciences, Microscopy, Confocal, 3D co-culture, invasion, University hospital, 3. Good health, Oncology, Cell Tracking, Research centre, 030220 oncology & carcinogenesis, Collagen, Algorithms, Research Paper, Cancer associated fibroblast, ta3111, Models, Biological, Time-Lapse Imaging, Cell Line, 03 medical and health sciences, Microscopy, Electron, Transmission, SDG 3 - Good Health and Well-being, Cell Line, Tumor, medicine, Humans, Tumor growth, Tumor stroma, Protein Kinase Inhibitors, Cell Proliferation, 030304 developmental biology, ta113, Tumor histology, Tumor microenvironment, cancer associated fibroblast (CAF), business.industry, phenotypic screening, ta1182, Granulocyte-Macrophage Colony-Stimulating Factor, Prostatic Neoplasms, Fibroblasts, ta3122, medicine.disease, Coculture Techniques, Focal Adhesion Protein-Tyrosine Kinases, Cancer research, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93326a6d15c89889a4ac7e1d2f45097Test
https://doi.org/10.18632/oncotarget.5046Test -
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المؤلفون: N. Mccabe, M. Congiano, Matthias Nees, Ian G. Mills, Pirkko Härkönen, S. Umbreen, N. Poulose, S. Afshan, I. Beumer, Simon S. McDade, Rebecca E Steele
المصدر: European Urology Supplements. 18:e3137
مصطلحات موضوعية: Multicellular organism, business.industry, medicine.drug_class, Urology, Medicine, business, Androgen, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d16910f86f7b7d865a9132b3e85cf7b8Test
https://doi.org/10.1016/s1569-9056Test(19)33379-2 -
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المؤلفون: Mervi Toriseva, L Yu, Matthias Nees, S. Umbreen, Ian G. Mills, Pirkko Härkönen, S. Afshan
المصدر: European Urology Supplements. 18:e3039
مصطلحات موضوعية: Prostate cancer, business.industry, Urology, medicine, Cancer research, medicine.disease, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4775a7b1c0fdc30cdbd95372e62fd63dTest
https://doi.org/10.1016/s1569-9056Test(19)33289-0 -
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المؤلفون: Mervi Toriseva, Laurent Guyon, Matthias Nees, Sean Robinson, Jaakko Nevalainen, Malin Åkerfelt
المساهمون: University of Turku, Laboratoire de Biologie à Grande Échelle (BGE - UMR S1038), Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Tampere School of Public Health, Turku Centre for Biotechnology, University of Turku-Åbo Academy University, Medical Biotechnology, VTT Technical Research Centre of Finland (VTT), Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Cancer Research Institute Ghent (CRIG), Ghent University [Belgium] (UGENT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Terveystieteiden yksikkö - School of Health Sciences, University of Tampere
المصدر: Robinson, S, Guyon, L, Nevalainen, J, Toriseva, M, Åkerfelt, M & Nees, M 2015, ' Segmentation of image data from complex organotypic 3D models of cancer tissues with Markov random fields ', PLoS ONE, vol. 10, no. 12, e143798 . https://doi.org/10.1371/journal.pone.0143798Test
PLoS ONE
PLoS ONE, Public Library of Science, 2015, 10 (12), ⟨10.1371/journal.pone.0143798⟩
PLoS ONE, Public Library of Science, 2015, 10 (12), pp.e0143798. ⟨10.1371/journal.pone.0143798⟩
PLoS ONE, 2015, 10 (12), ⟨10.1371/journal.pone.0143798⟩
PLoS ONE, Vol 10, Iss 12, p e0143798 (2015)مصطلحات موضوعية: Male, Cell type, Biolääketieteet - Biomedicine, [SDV]Life Sciences [q-bio], ta220, lcsh:Medicine, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, 02 engineering and technology, Biology, Bioinformatics, Models, Biological, 03 medical and health sciences, 3D cell culture, Imaging, Three-Dimensional, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Image Interpretation, Computer-Assisted, 0202 electrical engineering, electronic engineering, information engineering, Humans, Entropy (information theory), Segmentation, lcsh:Science, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, ta113, ta112, 0303 health sciences, Ground truth, Multidisciplinary, Random field, Markov chain, business.industry, lcsh:R, ta111, ta1182, Prostatic Neoplasms, Pattern recognition, Image segmentation, ta3122, Coculture Techniques, Markov Chains, Microscopy, Fluorescence, Multiphoton, lcsh:Q, 020201 artificial intelligence & image processing, Artificial intelligence, business, Research Article
وصف الملف: fulltext
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98802e75139190a45c326f6956c10bb7Test
https://cris.vtt.fi/en/publications/18071a24-2909-490d-9da8-99c973625faaTest -
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المؤلفون: Neslihan Bayramoglu, Janne Heikkilä, Malin Åkerfelt, Mika Kaakinen, Matthias Nees, Lauri Eklund, Juho Kannala
المصدر: ICIP
مصطلحات موضوعية: Pixel, business.industry, GLOH, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Pattern recognition, Filter (signal processing), ta3111, Pipeline (software), Independent component analysis, Image (mathematics), Computer Science::Computer Vision and Pattern Recognition, Histogram, Statistics, Computer vision, Artificial intelligence, Representation (mathematics), business, Mathematics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f036ab1cf0cff11a4978f6d2b375f20Test
http://juuli.fi/Record/0252566915Test -
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المؤلفون: Giovanna Angelini, Adriana Amaro, Ulrich Pfeffer, Anna Maria Gallina, Matthias Nees, Alessia Isabella Esposito, Adriana Albini
المساهمون: Amaro, A, Esposito, A, Gallina, A, Nees, M, Angelini, G, Albini, A, Pfeffer, U
المصدر: Amaro, A, Esposito, A I, Gallina, A, Nees, M, Angelini, G, Albini, A & Pfeffer, U 2014, ' Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel ', Cancer and Metastasis Reviews, vol. 33, no. 2-3, pp. 657-671 . https://doi.org/10.1007/s10555-013-9470-4Test
Cancer Metastasis Reviewsمصطلحات موضوعية: PCA3, Male, Cancer Research, Prognosi, Reproducibility of Result, Datasets as Topic, Disease, Bioinformatics, Article, Prostate cancer, PSA, SDG 3 - Good Health and Well-being, Prostate, medicine, Biomarkers, Tumor, Cluster Analysis, Humans, FLNC, prognostic signature, Multivariate Analysi, multivariae model, Cluster Analysi, business.industry, Gene Expression Profiling, Cancer, Prostatic Neoplasms, Reproducibility of Results, Biomarker, medicine.disease, Prognosis, prostate cancer, Gene expression profiling, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Oncology, Meta-analysis, Prostatic Neoplasm, Multivariate Analysis, Multivariate model, Neoplasm Grading, business, Biomarkers, Biomakers, Human
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34ad6b1506036f92ba62d96dfa63fddTest
https://cris.vtt.fi/en/publications/95dcf428-df5a-489d-82da-6c2b47b28a3cTest -
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المؤلفون: Juho Kannala, Neslihan Bayramoglu, Matthias Nees, Janne Heikkilä, Lauri Eklund, Malin Åkerfelt, Mika Kaakinen
المصدر: ICPR
Bayramoglu, N, Kaakinen, M, Eklund, L, Åkerfelt, M, Nees, M, Kannala, J & Heikkilä, J 2014, Detection of Tumor Cell Spheroids from Co-cultures Using Phase Contrast Images and Machine Learning Approach . in Proceedings : 22nd International Conference on Pattern Recognition, ICPR 2014 . IEEE Institute of Electrical and Electronic Engineers, pp. 3345-3350, 22nd International Conference on Pattern Recognition, ICPR 2014, Stockholm, Sweden, 24/08/14 . https://doi.org/10.1109/ICPR.2014.576Testمصطلحات موضوعية: Pixel, business.industry, Image quality, Computer science, Phase contrast microscopy, Phase-contrast imaging, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Machine learning, computer.software_genre, law.invention, Image (mathematics), Random forest, law, Feature (computer vision), Clutter, Segmentation, Computer vision, Artificial intelligence, business, computer
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130260d535d74406b11a0d58d9faa45cTest
https://cris.vtt.fi/en/publications/64a511a8-c723-45d8-aafe-cdf1614f88f5Test -
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المؤلفون: Heikki Seikkula, Johanna Tuomela, Peter J. Boström, Tuomas Mirtti, Matthias Nees, Kalle Alanen, Mervi Toriseva, Martti Nurmi, Markku Kallajoki, Pirkko Härkönen, Andrew Erickson, Lan Yu, Teresa Elo
المصدر: Cancer Research. 76:4951-4951
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, business.industry, Cancer, Fibroblast growth factor, medicine.disease, 3. Good health, Prostate cancer, medicine.anatomical_structure, Oncology, Fibroblast growth factor receptor, Tumor progression, Prostate, Cancer research, medicine, business, Intracellular part, Immunostaining
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4ebc3d738327c1deb93d9a069d1fc26cTest
https://doi.org/10.1158/1538-7445.am2016-4951Test
