نتائج البحث - "Katja Seipel"

1

Rationale for a Combination Therapy with the STAT5 Inhibitor AC-4-130 and the MCL1 Inhibitor S63845 in the Treatment of FLT3-Mutated or TET2-Mutated Acute Myeloid Leukemia

المؤلفون: Ulrike Bacher, Laura Flückiger, Thomas Pabst, Carolyn Graber, Katja Seipel

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 8092, p 8092 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
Seipel, Katja; Graber, Carolyn; Flückiger, Laura; Bacher, Vera; Pabst, Thomas (2021). Rationale for a Combination Therapy with the STAT5 Inhibitor AC-4-130 and the MCL1 Inhibitor S63845 in the Treatment of FLT3-Mutated or TET2-Mutated Acute Myeloid Leukemia. International journal of molecular sciences, 22(15) MDPI 10.3390/ijms22158092 <http://dx.doi.org/10.3390/ijms22158092Test>

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_compound, 0302 clinical medicine, fluids and secretions, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, STAT5 Transcription Factor, Medicine, MCL1, Midostaurin, Biology (General), Spectroscopy, Trametinib, Kinase, ten-eleven translocation-2 (TET2), Myeloid leukemia, hemic and immune systems, General Medicine, 3. Good health, Computer Science Applications, DNA-Binding Proteins, Leukemia, Myeloid, Acute, Chemistry, myeloid leukemia cell differentiation protein (MCL1), 030220 oncology & carcinogenesis, embryonic structures, FLT3 Inhibitor, Combination therapy, QH301-705.5, tumor suppressor p53 (TP53), 610 Medicine & health, Thiophenes, Article, Catalysis, Dioxygenases, Inorganic Chemistry, 03 medical and health sciences, signal transducer and activator of transcription 5 (STAT5), acute myeloid leukemia (AML), Cell Line, Tumor, Proto-Oncogene Proteins, Humans, hematological malignancies, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, FMS-like tyrosine kinase 3 (FLT3), business.industry, Venetoclax, Tumor Suppressor Proteins, Organic Chemistry, Pyrimidines, 030104 developmental biology, fms-Like Tyrosine Kinase 3, chemistry, Cancer research, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a86caaa2cbf92ffdc34d64b704e8471Test
https://www.mdpi.com/1422-0067/22/15/8092Test

2

Cancer Prognosis According to Parthanatos Features

المؤلفون: Katja Seipel, Alexandre Theocharides, Bruktawit Maru, Thomas Pabst, Maureen McKeague, Peter J. M. Valk, Nathan W. Luedtke, Alessandra Messikommer

مصطلحات موضوعية: Chemotherapy, Anthracycline, business.industry, medicine.medical_treatment, Cancer, Myeloid leukemia, medicine.disease, Olaparib, chemistry.chemical_compound, chemistry, Cancer cell, medicine, Cytarabine, Cancer research, Idarubicin, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b9e18174171c7986b9deb29ab5cb243eTest
https://doi.org/10.1101/2021.05.24.445484Test

3

BMI1-Inhibitor PTC596 in Combination with MCL1 Inhibitor S63845 or MEK Inhibitor Trametinib in the Treatment of Acute Leukemia

المؤلفون: Ulrike Bacher, Basil Kopp, Thomas Pabst, Katja Seipel

المصدر: Cancers, Vol 13, Iss 581, p 581 (2021)
Cancers
Volume 13
Issue 3
Seipel, Katja; Kopp, Basil; Bacher, Ulrike; Pabst, Thomas (2021). BMI1-Inhibitor PTC596 in Combination with MCL1 Inhibitor S63845 or MEK Inhibitor Trametinib in the Treatment of Acute Leukemia. Cancers, 13(3) MDPI AG 10.3390/cancers13030581 <http://dx.doi.org/10.3390/cancers13030581Test>

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, NPM1, CD34, 610 Medicine & health, BMI1 Inhibitor PTC596, myeloid cell leukemia 1 (MCL1), lcsh:RC254-282, Article, 03 medical and health sciences, meningioma 1 (MN1), 0302 clinical medicine, acute myeloid leukemia (AML), hemic and lymphatic diseases, Medicine, MCL1, neoplasms, Trametinib, Acute leukemia, business.industry, MEK inhibitor, Myeloid leukemia, myelodysplastic syndrome (MDS), lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1), 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, tumor suppressor protein 53 (TP53), Cancer research, business, hematopoietic progenitor cell antigen cluster of differentiation 34 (CD34)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba1f36042ffd3cdb925c7e8e62782eTest
https://www.mdpi.com/2072-6694/13/3/581Test

4

Iron overload is correlated with impaired autologous stem cell mobilization and survival in acute myeloid leukemia

المؤلفون: Ulrike Bacher, Urban Novak, Beatrice U. Mueller, Thomas Pabst, Behrouz Mansouri Taleghani, Laura C. Alva, Katja Seipel

المصدر: Transfusion. 58:2365-2373

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::90e093564c9159bba96f20bf2f7bbe0aTest
https://doi.org/10.1111/trf.14895Test

5

MDM2- and FLT3-inhibitors in the treatment of FLT3-ITD acute myeloid leukemia, specificity and efficacy of NVP-HDM201 and midostaurin

المؤلفون: Thomas Pabst, Miguel A.T. Marques, Beatrice U. Mueller, Katja Seipel, Corinne Sidler

المصدر: Haematologica

مصطلحات موضوعية: Acute Myeloid Leukemia, Male, 0301 basic medicine, NPM1, Myeloid, HL-60 Cells, Article, 03 medical and health sciences, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Cytotoxic T cell, Midostaurin, Enzyme Inhibitors, biology, business.industry, Wild type, Myeloid leukemia, Proto-Oncogene Proteins c-mdm2, hemic and immune systems, Hematology, Staurosporine, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, fms-Like Tyrosine Kinase 3, chemistry, 030220 oncology & carcinogenesis, embryonic structures, biology.protein, Cancer research, Mdm2, Female, business, Nucleophosmin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d87a3f46f05337d04f986dc39c79468Test
https://doi.org/10.3324/haematol.2018.191650Test

6

MN1, FOXP1 and hsa-miR-181a-5p as prognostic markers in acute myeloid leukemia patients treated with intensive induction chemotherapy and autologous stem cell transplantation

المؤلفون: Gertrud Wiedemann, Ulrike Bacher, Katja Seipel, Thomas Pabst, Christian Messerli

المصدر: Leukemia research. 89

مصطلحات موضوعية: Adult, Male, Cancer Research, Myeloid, CD34, Peripheral blood mononuclear cell, Models, Biological, Transplantation, Autologous, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Autologous stem-cell transplantation, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Medicine, Humans, 610 Medicine & health, Aged, Retrospective Studies, business.industry, Tumor Suppressor Proteins, Hematopoietic Stem Cell Transplantation, Induction chemotherapy, Myeloid leukemia, Forkhead Transcription Factors, Hematology, Induction Chemotherapy, Middle Aged, Prognosis, Gene Expression Regulation, Neoplastic, Repressor Proteins, Haematopoiesis, Leukemia, Myeloid, Acute, MicroRNAs, medicine.anatomical_structure, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer research, Trans-Activators, Female, Stem cell, business, Nucleophosmin, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df4593d94f150a7e9189cf98b99f336Test
https://pubmed.ncbi.nlm.nih.gov/31927137Test

7

NSAID treatment with meloxicam enhances peripheral stem cell mobilization in myeloma

المؤلفون: S Farese, Urban Novak, J-M Luethi, Gabriela M. Baerlocher, Thomas Pabst, Martin Bigler, Beatrice U. Mueller, B Mansouri Taleghani, Katja Seipel, Axel Ruefer, Barbara Jeker, Daniel Betticher

المصدر: Bone Marrow Transplantation. 53:175-179

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d39d870a9a5dfeef02ee51221e0967Test
https://doi.org/10.1038/bmt.2017.234Test

8

Consolidation with autologous stem cell transplantation in first remission is safe and effective in AML patients above 65 years

المؤلفون: Urban Novak, Yara Banz, Alexander D Heini, Martin D. Berger, Katja Seipel, Kurt Leibundgut, Behrouz Mansouri Taleghani, Gabriela M. Baerlocher, Thomas Pabst

المصدر: Leukemia Research. 53:28-34

مصطلحات موضوعية: Male, Oncology, Cancer Research, medicine.medical_specialty, Transplantation Conditioning, Allogeneic transplantation, Cyclophosphamide, medicine.medical_treatment, Hematopoietic stem cell transplantation, Transplantation, Autologous, 03 medical and health sciences, 0302 clinical medicine, Autologous stem-cell transplantation, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Autologous transplantation, 610 Medicine & health, Busulfan, neoplasms, Survival rate, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Remission Induction, Age Factors, Hematopoietic Stem Cell Transplantation, Hematology, humanities, Surgery, Survival Rate, Leukemia, Myeloid, Acute, Treatment Outcome, 030220 oncology & carcinogenesis, 570 Life sciences, biology, Female, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53332fa4ce07a3bdc5671013846c1f63Test
https://doi.org/10.1016/j.leukres.2016.12.001Test

9

Autologous stem cell transplantation in elderly patients with multiple myeloma: evaluation of its safety and efficacy

المؤلفون: Gabriela M. Baerlocher, Jasmin Stettler, Thomas Pabst, Katja Seipel, Urban Novak, Behrouz Mansouri Taleghani

المصدر: Stettler, Jasmin; Novak, Urban; Baerlocher, Gabriela M.; Seipel, Katja; Mansouri Taleghani, Behrouz; Pabst, Thomas (2017). Autologous stem cell transplantation in elderly patients with multiple myeloma: evaluation of its safety and efficacy. Leukemia & lymphoma, 58(5), pp. 1076-1083. Informa Healthcare 10.1080/10428194.2016.1233542 <http://dx.doi.org/10.1080/10428194.2016.1233542Test>

مصطلحات موضوعية: Adult, Male, Oncology, Melphalan, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, 610 Medicine & health, Kaplan-Meier Estimate, Transplantation, Autologous, 03 medical and health sciences, 0302 clinical medicine, Autologous stem-cell transplantation, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Multiple myeloma, Aged, Neoplasm Staging, Aged, 80 and over, Chemotherapy, business.industry, Platelet recovery, Age Factors, Hematopoietic Stem Cell Transplantation, Hematology, Middle Aged, medicine.disease, Treatment related mortality, Surgery, Immunoglobulin Isotypes, Treatment Outcome, 030220 oncology & carcinogenesis, Toxicity, Female, Stem cell, Multiple Myeloma, business, Biomarkers, 030215 immunology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2815c999de70734988055d204c9e59c2Test
https://doi.org/10.1080/10428194.2016.1233542Test

10

Rebound Thrombocytosis after Induction Chemotherapy is a Strong Biomarker for Favorable Outcome in AML Patients

المؤلفون: Yara Banz, Urban Novak, Beatrice U. Mueller, Ulrike Bacher, Thomas Pabst, Bianca R Schnell, Katja Seipel, Barbara Jeker

المصدر: HemaSphere
Schnell, Bianca R.; Seipel, Katja; Bacher, Ulrike; Jeker, Barbara; Mueller, Beatrice U.; Banz, Yara; Novak, Urban; Pabst, Thomas (2019). Rebound Thrombocytosis after Induction Chemotherapy is a Strong Biomarker for Favorable Outcome in AML Patients. HemaSphere, 3(2), e180. Wolters Kluwer Health 10.1097/HS9.0000000000000180 <http://dx.doi.org/10.1097/HS9.0000000000000180Test>
HemaSphere, Vol 3, Iss 2 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcbfaa14c6b285f3d9eaaaf27171dc3Test
http://europepmc.org/articles/PMC6746035Test

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