نتائج البحث - "Jean Pierre J. Issa"

1

Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial

المصدر: The Lancet Haematology. 6:e317-e327

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Neutropenia, Adolescent, Decitabine, Antineoplastic Agents, Severity of Illness Index, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Clinical endpoint, Humans, Adverse effect, Survival rate, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Hematology, Middle Aged, medicine.disease, Thrombocytopenia, Survival Rate, Treatment Outcome, Tolerability, Hypomethylating agent, International Prognostic Scoring System, Myelodysplastic Syndromes, 030220 oncology & carcinogenesis, Azacitidine, Female, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020d3a14be9a90c2cbe74c5f5714074dTest
https://doi.org/10.1016/s2352-3026Test(19)30029-8

2

Abstract 139: Promoter Methylation Changes in ALOX12, AIRE1, and NETO1 : Novel Epigenetic Markers for Atherosclerosis

المؤلفون: Jee Yeon Kim, Geun-Eun Kim, Young Ho Lee, Dae-Hyun Kim, Kwangjo Cho, Sun U. Kwon, Bong-Gen Choi, Jean Pierre J. Issa, Seo Hee Rha, Junha Hwang, Jaroslav Jelinek, Jei Kim, Jae Kwan Cha

المصدر: Stroke. 51

مصطلحات موضوعية: Advanced and Specialized Nursing, ALOX12, business.industry, Promoter methylation, Cancer research, Medicine, Neurology (clinical), Epigenetics, Cardiology and Cardiovascular Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5029f7ad09ee089f9fc0efb19adc07f6Test
https://doi.org/10.1161/str.51.suppl_1.139Test

3

Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion

المؤلفون: Geoffroy Laumet, Jozef Madzo, Judit Garriga, Jaroslav Jelinek, Hui Lin Pan, Jean Pierre J. Issa, Shao Rui Chen, Yuhao Zhang

المصدر: The Journal of Neuroscience. 38:6090-6101

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8dd4ac1231eb6425304ea503954242Test
https://doi.org/10.1523/jneurosci.2616-17.2018Test

4

Engineering of Chimeric Antigen Receptor T Cells with integrin αEβ7 Results in Augmented Therapeutic Efficacy against E-cadherin positive tumor

المؤلفون: Essel Dulaimi, Hongxing Sun, Lei-Zhen Zheng, Jean Pierre J. Issa, Yongnian Liu, Min Tao, Yi Zhang, Shan He, Henry C. Fung, Jian Wang, Ying Wang, Hanghang Zhang, Lijun Meng, Stefan K. Barta

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a584c8d8e74e1d45445babf5544c9f7aTest

5

Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia

المؤلفون: Katherine Walsh, Casey O'Connell, David A. Rizzieri, Gail J. Roboz, Jean Pierre J. Issa, Hagop M. Kantarjian, James N. Lowder, Karen W.L. Yee, Yong Hao, Elias Jabbour, Woonbok Chung, Scott D. Lunin, Elizabeth A. Griffiths, Wendy Stock, Tania Curio, Ellen K. Ritchie, Patricia Kropf, Naval Daver, Mohammad Azab

المصدر: Cancer. 124:325-334

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4424701f2379bcf2b48e1827f1065f85Test
https://doi.org/10.1002/cncr.31138Test

6

Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: phase 2 results from a multicentre, randomised, phase 1/2 trial

المصدر: The Lancet Oncology. 18:1317-1326

مصطلحات موضوعية: Adult, 0301 basic medicine, medicine.medical_specialty, Maximum Tolerated Dose, Population, Phases of clinical research, Decitabine, Kaplan-Meier Estimate, Neutropenia, Risk Assessment, Disease-Free Survival, Drug Administration Schedule, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Neoplasm Invasiveness, Prospective Studies, Infusions, Intravenous, education, Prospective cohort study, Aged, Neoplasm Staging, Aged, 80 and over, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Remission Induction, Age Factors, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Surgery, Leukemia, Myeloid, Acute, Regimen, Treatment Outcome, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Azacitidine, Patient Safety, business, Febrile neutropenia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831965ab308b57b5ad258bda3c291389Test
https://doi.org/10.1016/s1470-2045Test(17)30576-4

7

Epigenetics and Precision Oncology

المؤلفون: Andrew Kelly, Jean Pierre J. Issa, Rachael J. Werner

المصدر: The Cancer Journal. 23:262-269

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28bb0da7be45bc20e80e41e81f7e91aTest
https://doi.org/10.1097/ppo.0000000000000281Test

8

Abstract CT121: A Phase II trial of guadecitabine (G) plus atezolizumab (A) in patients with metastatic urothelial carcinoma (UC) progressing after initial checkpoint inhibitor therapy

المؤلفون: Peter W. Nichols, Hyo Sik Jang, Jean Pierre J. Issa, Peter A. Jones, Hui Shen, Elizabeth R. Plimack, Toshinori Hinoue, Kerry S. Campbell, Hitoshi Ohtani, Galen Hostetter, Noah M. Hahn, David I. Quinn, Jozef Madzo, Woonbok Chung, Stephen B. Baylin

المصدر: Cancer Research. 81:CT121-CT121

مصطلحات موضوعية: Cancer Research, Metastatic Urothelial Carcinoma, Oncology, Guadecitabine, business.industry, Atezolizumab, Immune checkpoint inhibitors, Cancer research, Medicine, In patient, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0d504f05b7375f79093c1212c8fd7bbaTest
https://doi.org/10.1158/1538-7445.am2021-ct121Test

9

Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia

المؤلفون: Jean Pierre J. Issa, Hagop M. Kantarjian, Jaroslav Jelinek, Henry C. Fung, Mohammad Azab, Patricia Kropf, Woonbok Chung, Xiang Yao Su, Gail J. Roboz, Andrew Kelly

المصدر: Clinical Epigenetics

مصطلحات موضوعية: 0301 basic medicine, Oncology, Neuroblastoma RAS viral oncogene homolog, Male, medicine.disease_cause, 0302 clinical medicine, AML, CDKN2B, Genetics (clinical), Aged, 80 and over, Myeloid leukemia, Genomics, Guadecitabine, Middle Aged, 3. Good health, Leukemia, Leukemia, Myeloid, Acute, Treatment Outcome, 030220 oncology & carcinogenesis, DNA methylation, Azacitidine, Female, KRAS, Mutations, Adult, medicine.medical_specialty, DNA methyltransferase, 03 medical and health sciences, Young Adult, DNA methylation inhibitor, Internal medicine, Genetics, medicine, Biomarkers, Tumor, Humans, Molecular Biology, Survival rate, Aged, business.industry, Research, DNA Methylation, medicine.disease, Survival Analysis, 030104 developmental biology, Drug resistance, Mutation, Gene expression, Neoplasm Recurrence, Local, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba87adcbd903da019b3a83670791cfaTest
http://europepmc.org/articles/PMC6647096Test

10

Gestational high fat diet protects 3xTg offspring from memory impairments, synaptic dysfunction, and brain pathology

المؤلفون: Elisabetta Lauretti, Jean Pierre J. Issa, Antonio Di Meco, Domenico Praticò, Mary Elizabeth Curtis, Jaroslav Jelinek

المصدر: Molecular psychiatry

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Disease, memory, Mice, 0302 clinical medicine, Pregnancy, synapse, tau, Brain Diseases, high fat diet, Brain, FOXP2, Forkhead Transcription Factors, Amyloidosis, Up-Regulation, Psychiatry and Mental health, In utero, Gestation, Female, Alzheimer’s disease, medicine.medical_specialty, Offspring, Transgene, Mice, Transgenic, tau Proteins, Neuropathology, transgenic mice, Diet, High-Fat, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Downregulation and upregulation, Alzheimer Disease, Internal medicine, medicine, Animals, Genetic Predisposition to Disease, Molecular Biology, Memory Disorders, Amyloid beta-Peptides, business.industry, Repressor Proteins, amyloid beta, Disease Models, Animal, maternal, 030104 developmental biology, Endocrinology, Synapses, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d994671656fb0255c5a192a6c86689aTest
https://pubmed.ncbi.nlm.nih.gov/31451749Test

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