نتائج البحث - "Jan C, Brase"

وصف الملف: 841_Dummer_R._et_al._Adjuvant_dabrafenib_plus_trametinib_versus_placebo_in_patients_with_resected,_BRAFV600_mutant,_stage_III_melanoma_etc_Lancet_Oncology_2020.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8deeff612b475730ab4040608e0e18baTest
https://www.zora.uzh.ch/id/eprint/187679Test/

5

HER2-enriched subtype and pathological complete response in HER2-positive breast cancer: a systematic review and meta-analysis

المساهمون: Schettini, F., Pascual, T., Conte, B., Chic, N., Braso-Maristany, F., Galvan, P., Martinez, O., Adamo, B., Vidal, M., Munoz, M., Fernandez-Martinez, A., Rognoni, C., Griguolo, G., Guarneri, V., Conte, P. F., Locci, M., Brase, J. C., Gonzalez-Farre, B., Villagrasa, P., De Placido, S., Schiff, R., Veeraraghavan, J., Rimawi, M. F., Osborne, C. K., Pernas, S., Perou, C. M., Carey, L. A., Prat, A.

المصدر: Cancer Treat Rev

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, BIOMARKER, BREAST CANCER, HER2-ENRICHED, HER2-POSITIVE, PAM50, PATHOLOGIC COMPLETE RESPONSE, Receptor, ErbB-2, medicine.medical_treatment, Breast Neoplasms, Disease, Article, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, ErbB-2, Internal medicine, Pathologic complete response, medicine, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, PAM50, skin and connective tissue diseases, neoplasms, Neoadjuvant therapy, Neoplasm Staging, Chemotherapy, Tumor, business.industry, Remission Induction, Biomarker, HER2-Enriched, HER2-positive, Female, Neoadjuvant Therapy, General Medicine, Odds ratio, medicine.disease, Genomic Biomarker, 030104 developmental biology, 030220 oncology & carcinogenesis, Meta-analysis, Biomarker (medicine), business, Biomarkers, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456360a8625da925d93580bf31f87b0fTest
https://europepmc.org/articles/PMC7230134Test/

6

Effect of first-line spartalizumab + dabrafenib + trametinib on immunosuppressive features detected in peripheral blood and clinical outcome in patients (pts) with advanced BRAF V600–mutant melanoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4427df5cbb6f0c621237dae3895445f3Test

7

Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma : safety run-in and biomarker cohorts of COMBI-i

المساهمون: University of Zurich, Dummer, Reinhard

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Skin Neoplasms, Medizin, Cohort Studies, 0302 clinical medicine, Antineoplastic Agents, Immunological, Antineoplastic Combined Chemotherapy Protocols, Oximes, Clinical endpoint, Neoplasm Metastasis, Immune Checkpoint Inhibitors, Melanoma, Trametinib, MEK inhibitor, Imidazoles, 10177 Dermatology Clinic, General Medicine, Middle Aged, MAP Kinase Kinase Kinases, Treatment Outcome, 030220 oncology & carcinogenesis, Disease Progression, Biomarker (medicine), Female, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Pyridones, Mutation, Missense, 610 Medicine & health, Genetics and Molecular Biology, Pyrimidinones, Antibodies, Monoclonal, Humanized, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Young Adult, 1300 General Biochemistry, Genetics and Molecular Biology, Internal medicine, medicine, Biomarkers, Tumor, Humans, Protein Kinase Inhibitors, Aged, business.industry, Dabrafenib, medicine.disease, Clinical trial, Regimen, 030104 developmental biology, General Biochemistry, business

وصف الملف: 870_Dummer_R._et_al._Combined_PD-1,_BRAF_and_MEK_inhibition_in_advanced_BRAF-mutant_melanoma_Nature_Medicine_2020.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b17ee96d80a3281cdd7448c58c9110fTest
https://www.ncbi.nlm.nih.gov/pubmed/33020648Test

8

BRAF-mutant ctDNA predicts outcomes

المؤلفون: Jean-Jacques Grob, Mahrukh M. Syeda, Antoni Ribas, Georgina V. Long, Mahtab Marker, Broderick Corless, Dirk Schadendorf, Keith T. Flaherty, James Garrett, David Polsky, Eduard Gasal, Matthew Squires, Caroline Robert, Jan C. Brase, Jennifer M. Wiggins, Michael A. Davies, Paul Nathan

المصدر: Lancet Oncol
The Lancet. Oncology, vol 22, iss 3

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Mutant, Medizin, Phases of clinical research, Bioinformatics, Circulating Tumor DNA, 0302 clinical medicine, Oximes, Antineoplastic Combined Chemotherapy Protocols, Medicine, Melanoma, Cancer, Trametinib, screening and diagnosis, Brain Neoplasms, MEK inhibitor, Hazard ratio, Imidazoles, Middle Aged, Prognosis, Survival Rate, Detection, 030220 oncology & carcinogenesis, Female, 4.2 Evaluation of markers and technologies, medicine.drug, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Pyridones, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, MEDLINE, Pyrimidinones, Article, 03 medical and health sciences, Text mining, Double-Blind Method, Clinical Research, Internal medicine, Humans, Oncology & Carcinogenesis, Survival rate, Aged, Performance status, business.industry, Dabrafenib, medicine.disease, Good Health and Well Being, 030104 developmental biology, Cancer genetics, business, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c3f1a9278111f2f965a594f4bbb278Test
https://doi.org/10.1038/s41571-021-00494-0Test

9

A randomized, open-label, phase 2 study of everolimus in combination with pasireotide LAR or everolimus alone in advanced, well-differentiated, progressive pancreatic neuroendocrine tumors: COOPERATE-2 trial

المؤلفون: Maurizio Voi, Juan W. Valle, W. W. de Herder, D. Smith, Lida Bubuteishvili-Pacaud, Marianne Pavel, Matthew H. Kulke, Jan C. Brase, C. Lombard-Bohas, James C. Yao, R. Salazar, Evgeny Degtyarev, R. P. Riechelmann, Ivan Borbath, Philippe Ruszniewski, Nicola Fazio, E. Van Cutsem, Jaume Capdevila

المساهمون: Internal Medicine

المصدر: Ann Oncol
Kulke, M H, Ruszniewski, P, Van Cutsem, E, Lombard-Bohas, C, Valle, J, De Herder, W W, Pavel, M, Degtyareva, E, Brase, J C, Pacaud, L B, Voi, M, Salazar, R, Borbath, I, Fazio, N, Smith, D, Capdevila, J, Riechelmann, R P & Yao, J C 2017, ' A randomized, open-label, phase 2 study of everolimus in combination with pasireotide LAR or everolimus alone in advanced, well-differentiated, progressive pancreatic neuroendocrine tumors : COOPERATE-2 trial ', Annals of Oncology, vol. 28, no. 6, mdx078 . https://doi.org/10.1093/annonc/mdx078Test
Annals of Oncology, 28(6), 1309-1315. Elsevier Ltd.

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Phases of clinical research, Neuroendocrine tumors, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Clinical endpoint, Humans, Everolimus, Progression-free survival, Adverse effect, GASTROINTESTINAL TUMOR, Aged, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Hazard ratio, Hematology, Middle Aged, medicine.disease, Survival Analysis, Corrigenda, Pasireotide, Pancreatic Neoplasms, Neuroendocrine Tumors, 030104 developmental biology, Endocrinology, chemistry, 030220 oncology & carcinogenesis, Disease Progression, Female, Somatostatin, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a731598e62b38701a6cb1e632c0a43Test
https://pure.eur.nl/en/publications/d82d3862-955a-415f-8cfc-2d09cb8cfa0cTest

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Circulating tumor DNA (ctDNA) kinetics to predict survival in patients (pts) with unresectable or metastatic melanoma treated with dabrafenib (D) or D + trametinib (T)

المؤلفون: Georgina V. Long, Paul Nathan, Mahrukh M. Syeda, David Polsky, Michael A. Davies, Eduard Gasal, Dirk Schadendorf, Jean-Jacques Grob, Mahtab Marker, Keith T. Flaherty, Caroline Robert, Antoni Ribas, Jan C. Brase, Matthew Squires, Jennifer M. Wiggins, Broderick Corless

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b86e39c367b57f167b9e41cff430785Test

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