المؤلفون: Jennifer Vandooren, Jack van Horssen, Ivo Lambrichts, Melissa Schepers, Chris Van den Haute, Ghislain Opdenakker, Helena Slaets, Wia Baron, Veerle Baekelandt, Niels Hellings, Tim Vanmierlo, Evelien Houben, Doryssa Hermans, Bieke Broux, Kris Janssens

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Molecular Neuroscience and Ageing Research (MOLAR), Vandooren, Jennifer/0000-0002-7157-3370, Lambrichts, Ivo/0000-0001-7520-0021, Opdenakker, Ghislain/0000-0003-1714-2294, HOUBEN, Evelien, JANSSENS, Kris, HERMANS, Doryssa, Vandooren, Jennifer, Van den Haute, Chris, SCHEPERS, Melissa, VANMIERLO, Tim, LAMBRICHTS, Ivo, VAN HORSSEN, Jack, Baekelandt, Veerle, OPDENAKKER, Ghislain, Baron, Wia, BROUX, Bieke, Slaets, Helena, HELLINGS, Niels, Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 117(9), 5028-5038. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(9), 5028-5038. NATL ACAD SCIENCES
Houben, E, Janssens, K, Hermans, D, Vandooren, J, van den Haute, C, Schepers, M, Vanmierlo, T, Lambrichts, I, van Horssen, J, Baekelandt, V, Opdenakker, G, Baron, W, Broux, B, Slaets, H & Hellings, N 2020, ' Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 9, pp. 5028-5038 . https://doi.org/10.1073/pnas.1912910117Test
Article

مصطلحات موضوعية: Central Nervous System, EXPRESSION, Multiple Sclerosis, Central nervous system, oligodendrocyte precursor cells, Matrix metalloproteinase, UP-REGULATION, PROTECTS, Myelin, Mice, Downregulation and upregulation, OLIGODENDROCYTE PROGENITOR CELLS, medicine, Animals, Humans, Remyelination, Demyelinating Disorder, Myelin Sheath, Mice, Knockout, Multidisciplinary, Tissue Inhibitor of Metalloproteinase-1, biology, RECEPTOR, business.industry, Interleukin-6, LIF, Multiple sclerosis, CENTRAL-NERVOUS-SYSTEM, Oncostatin M, astrocytes, MULTIPLE-SCLEROSIS, MEDIATED DEMYELINATION, Biological Sciences, medicine.disease, Axons, Cell biology, medicine.anatomical_structure, remyelination, biology.protein, CNS, business, tissue inhibitor of metalloproteinases-1, Demyelinating Diseases, oncostatin M

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf8b8166fe05f82c9125f02c7197a1Test
https://doi.org/10.1073/pnas.1912910117Test

المؤلفون: Gijs Kooij, Jack van Horssen, Alexandre Prat, Ruud D. Fontijn, Elizabeth Gowing, Marc Charabati, Bert van het Hof, Imad Didouh, Helga E. de Vries, Dirk Geerts, Susanne M. A. van der Pol, Claudio Derada Troletti

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neurovascular Disorders, Hematology laboratory, Amsterdam Neuroscience - Neuroinfection & -inflammation, AII - Inflammatory diseases, ACS - Microcirculation, CCA - Cancer biology and immunology, Medical Biology

المصدر: Cell Death and Disease, Vol 10, Iss 2, Pp 1-13 (2019)
Cell Death and Disease, 10(2):45. Nature Publishing Group
Cell death & disease, 10(2). Nature Publishing Group
Derada Troletti, C, Fontijn, R D, Gowing, E, Charabati, M, van Het Hof, B, Didouh, I, van der Pol, S M A, Geerts, D, Prat, A, van Horssen, J, Kooij, G & de Vries, H E 2019, ' Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology ', Cell Death and Disease, vol. 10, no. 2, 45 . https://doi.org/10.1038/s41419-018-1294-2Test
Cell Death & Disease
Cell death & disease, 10(2):45. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Multiple Sclerosis, Immunology, Inflammation, Neuroprotection, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Downregulation and upregulation, Humans, Medicine, Epithelial–mesenchymal transition, lcsh:QH573-671, Cells, Cultured, business.industry, lcsh:Cytology, Multiple sclerosis, Mesenchymal stem cell, Brain, Endothelial Cells, Cell Biology, medicine.disease, Cell biology, Endothelial stem cell, 030104 developmental biology, SNAI1, medicine.symptom, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9de50a6066f1229083128ebde12736Test
http://link.springer.com/article/10.1038/s41419-018-1294-2Test

المؤلفون: Philip Scheltens, Charlotte E. Teunissen, Victor L. Thijssen, Ananya Chakraborty, Ruud D. Fontijn, Alwin Kamermans, Ed Aanhane, Bert van het Hof, Jack van Horssen, Kitty C. M. Castricum, Wiesje M. van der Flier, Helga E. de Vries

المساهمون: Molecular cell biology and Immunology, Medical oncology laboratory, Radiation Oncology, Neurology, Clinical chemistry, Amsterdam Neuroscience - Neurovascular Disorders, APH - Personalized Medicine, APH - Methodology, Epidemiology and Data Science, ACS - Microcirculation

المصدر: Chakraborty, A, Kamermans, A, van Het Hof, B, Castricum, K, Aanhane, E, van Horssen, J, Thijssen, V L, Scheltens, P, Teunissen, C E, Fontijn, R D, van der Flier, W M & de Vries, H E 2018, ' Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy ', Brain : a journal of neurology, vol. 141, no. 12, pp. 3377-3388 . https://doi.org/10.1093/brain/awy274Test
Brain : a journal of neurology, 141(12), 3377-3388

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Angiopoietin-like 4 Protein, Vascular Remodeling, Blood–brain barrier, Vascular remodelling in the embryo, Angiopoietin, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Angiopoietin-Like Protein 4, Humans, Medicine, Vascular dementia, Aged, Aged, 80 and over, business.industry, Brain, Endothelial Cells, Human brain, medicine.disease, Cell Hypoxia, Endothelial stem cell, Cerebral Amyloid Angiopathy, 030104 developmental biology, medicine.anatomical_structure, Astrocytes, Microvessels, Female, Neurology (clinical), Cerebral amyloid angiopathy, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b850238bc9029d2faf99131bddf794dTest
https://doi.org/10.1093/brain/awy274Test

المؤلفون: Artem A Shaposhnykov, Marc Freichel, Celina Schwencke-Westphal, Maarten E. Witte, Nanne Paauw, Ole Pless, Jan Broder Engler, Sina C. Rosenkranz, Vanessa Vieira, Jack van Horssen, Lukas Can Bal, Benjamin Schattling, Simone Bauer, Charlotte Schubert, Vanessa Roth, Simone Träger, Manuel A. Friese

مصطلحات موضوعية: business.industry, Multiple sclerosis, Neurodegeneration, medicine, medicine.disease, business, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b6fb0804a7295cadd08a4e5eb4b484c1Test
https://doi.org/10.7554/elife.61798.sa2Test

المؤلفون: Niels Hellings, Bieke Broux, Jack van Horssen, Tim Vanmierlo

المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience

المصدر: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, 11:1425. Frontiers Media S.A.

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, business.industry, Immunology, Central nervous system, neuroimmunology, central nervous system, CNS repair, immune system, Neuroimmunology, Immune system, medicine.anatomical_structure, CNS disorders, Immunology and Allergy, Medicine, business, lcsh:RC581-607, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccfd1658fc3eb8e98b4d3799445621bTest
https://doi.org/10.3389/fimmu.2020.01425Test

المؤلفون: Jack van Horssen, Bieke Broux, Niels Hellings, Tim Vanmierlo

المصدر: Frontiers in Immunology
Frontiers Research Topics ISBN: 9782889660070

مصطلحات موضوعية: business.industry, Neuroimmunomodulation, Central nervous system, Immunology, neuroimmunology, central nervous system, CNS repair, Nerve Regeneration, immune system, medicine.anatomical_structure, Immune system, Neuroimmunology, Editorial, CNS disorders, Central Nervous System Diseases, medicine, Animals, Humans, business, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0173bac12150d275f3b7beee7894a63cTest
https://pubmed.ncbi.nlm.nih.gov/32793198Test

المؤلفون: Cyra E. Leurs, Fredrik Piehl, Martijn D. Steenwijk, Lisanne J. Balk, Petar Podlesniy, Jack van Horssen, Joep Killestein, Bernard M. J. Uitdehaag, Arjan Malekzadeh, Ramon Trullas, Charlotte E. Teunissen

المساهمون: Neurology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Anatomy and neurosciences, Clinical chemistry, Molecular cell biology and Immunology, Ministerio de Economía y Competitividad (España), Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España)

المصدر: Multiple Sclerosis, 24(4), 472-480. SAGE Publications Ltd
Leurs, C E, Podlesniy, P, Trullas, R, Balk, L, Steenwijk, M D, Malekzadeh, A, Piehl, F, Uitdehaag, B M, Killestein, J, van Horssen, J & Teunissen, C E 2018, ' Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment ', Multiple Sclerosis, vol. 24, no. 4, pp. 472-480 . https://doi.org/10.1177/1352458517699874Test
Digital.CSIC. Repositorio Institucional del CSIC
instname
Multiple Sclerosis (Houndmills, Basingstoke, England)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Mitochondrial DNA, Pathology, medicine.medical_specialty, Multiple Sclerosis, mitochondrial DNA, Disease, Mitochondrion, DNA, Mitochondrial, cerebrospinal fluid, Multiple sclerosis, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, 0302 clinical medicine, Cerebrospinal fluid, Humans, Medicine, Digital polymerase chain reaction, digital PCR, business.industry, biomarkers, Middle Aged, Multiple Sclerosis, Chronic Progressive, Clinical disease, medicine.disease, Mitochondria, 030104 developmental biology, Neurology, Feature (computer vision), Disease Progression, Female, Neurology (clinical), business, Original Research Papers, Digital PCR, Biomarkers, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97236814d071b50e0db7c4c6f9bc29a6Test
https://doi.org/10.1177/1352458517699874Test

المؤلفون: Ellen Boelen, Peter Delputte, Dirk Elewaut, Jack van Horssen, Els Louagie, Niels Hellings, Jerome Hendriks, Jeroen F. J. Bogie

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Multiple Sclerosis, 24(3), 290-300. SAGE Publications Ltd
Bogie, J F, Boelen, E, Louagie, E, Delputte, P, Elewaut, D, van Horssen, J, Hendriks, J J & Hellings, N 2018, ' CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis ', Multiple Sclerosis, vol. 24, no. 3, pp. 290-300 . https://doi.org/10.1177/1352458517698759Test
Multiple sclerosis: clinical and laboratory research

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Sialic Acid Binding Ig-like Lectin 1, Highly pathogenic, EAE, microglia, monocytes, neuroinflammation, sialoadhesin, CD169, Siglec-1, multiple sclerosis, Mice, 03 medical and health sciences, Sialoadhesin, Animals, Humans, Medicine, Pathophysiology of multiple sclerosis, Biology, Neuroinflammation, Aged, Inflammation, Phagocytes, Microglia, business.industry, Effector, Multiple sclerosis, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Neurology, Immunology, Female, Human medicine, Neurology (clinical), business, Engineering sciences. Technology, Biomarkers

وصف الملف: application/pdf; pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c00499d0495531fe30bb7526d6bff9aTest
https://doi.org/10.1177/1352458517698759Test

المؤلفون: Elien Wouters, Dieter Lütjohann, Jerome J. A. Hendriks, Jeroen F. J. Bogie, Tim Vanmierlo, Jo Mailleux, Jack van Horssen

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Multiple Sclerosis, 24(3), 279-289. SAGE Publications Ltd
Mailleux, J, Vanmierlo, T, Bogie, J F, Wouters, E, Lütjohann, D, Hendriks, J J & van Horssen, J 2018, ' Active liver X receptor signaling in phagocytes in multiple sclerosis lesions ', Multiple Sclerosis, vol. 24, no. 3, pp. 279-289 . https://doi.org/10.1177/1352458517696595Test

مصطلحات موضوعية: 0301 basic medicine, Multiple Sclerosis, Phagocytosis, Tissue Banks, 03 medical and health sciences, Myelin, chemistry.chemical_compound, 0302 clinical medicine, polycyclic compounds, Humans, Medicine, Liver X receptor, Cells, Cultured, Myelin Sheath, Liver X Receptors, business.industry, Macrophages, Multiple sclerosis, Brain, demyelinating diseases, multiple sclerosis, myelin sheath, phagocytes, liver X receptor, 27-hydroxycholesterol, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Neurology, chemistry, Myelin sheath, Immunology, 27-Hydroxycholesterol, lipids (amino acids, peptides, and proteins), Neurology (clinical), business, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3544204d18edeb350d531f5059a31bTest
https://doi.org/10.1177/1352458517696595Test

المؤلفون: Jack van Horssen, Maarten E. Witte

المصدر: Witte, M E & van Horssen, J 2017, ' Experimental models of cortical multiple sclerosis pathology ', Drug Discovery Today: Disease Models, vol. 25-26, pp. 69-74 . https://doi.org/10.1016/j.ddmod.2018.09.002Test

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, business.industry, Multiple sclerosis, Disease progression, Neurodegeneration, Grey matter, medicine.disease, Neuroprotection, 03 medical and health sciences, Microglial cell activation, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Drug Discovery, Molecular Medicine, Medicine, business, Pathological, 030217 neurology & neurosurgery, Cortical atrophy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f291adfccfe899f7599407de472097f2Test
https://doi.org/10.1016/j.ddmod.2018.09.002Test