المؤلفون: M. W. F. van Spengler, Ron A. A. Mathôt, Tim Preijers, Frank W.G. Leebeek, Marjon H. Cnossen, K. Fijnvandraat, Karina Meijer, Krista Fischer

المساهمون: Hematology, Pediatrics, Faculteit Medische Wetenschappen/UMCG, Video & Image Sense Lab (IvI, FNWI), Pharmacy, Paediatric Haematology, ARD - Amsterdam Reproduction and Development, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: European Journal of Clinical Pharmacology, 78(2), 237-249. Springer-Verlag
European Journal of Clinical Pharmacology, 78(2), 237-249. Springer Verlag
European journal of clinical pharmacology, 78(2). Springer Verlag
European journal of clinical pharmacology, 78(2), 237-249. Springer Verlag
European Journal of Clinical Pharmacology

مصطلحات موضوعية: FUSION PROTEIN, Individualized dosing, Metabolic Clearance Rate, Recombinant Fusion Proteins, Population, Models, Biological, Hemophilia B, Drug Administration Schedule, PROPHYLAXIS, Factor IX, Pharmacokinetics, Limited sampling, medicine, Humans, Pharmacology (medical), Dosing, education, Serum Albumin, Mathematics, Pharmacology, education.field_of_study, Coagulation factor IX, Dose-Response Relationship, Drug, business.industry, FACTOR-VIII, Body Weight, Half-life, General Medicine, Pharmacokinetics and Disposition, Computer simulation, POPULATION PHARMACOKINETICS, Blood Coagulation Factors, Immunoglobulin Fc Fragments, Delayed-Action Preparations, Weekly dose, Coagulation factor concentrates, Drug Monitoring, Nuclear medicine, business, Monte Carlo Method, RECOMBINANT FACTOR-IX, Half-Life, medicine.drug

وصف الملف: application/pdf

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http://www.scopus.com/inward/record.url?scp=85116989191&partnerID=8YFLogxKTest

المؤلفون: Bader Madoukh, Reem A. Mustafa, Omar Abughanimeh, John Roller, Paula D. James, Abdallah El Alayli, Hani Alturkmani, Mohamad A. Kalot, Alberto Tosetto, Ahmad Bilal Dimassi, Frank W.G. Leebeek, Michael Laffan, Peter A. Kouides, Veronica H. Flood, Yazan Aljabirii, Shaneela Shahid, Alec Britt, Shahrzad Motaghi, Sarah H. O'Brien, Jean M. Grow, Nedaa Husainat, Alice Arapshian, Nathan T. Connell, Romina Brignardello-Petersen, Hussein El Khechen

المصدر: Blood Advances

مصطلحات موضوعية: medicine.medical_specialty, MEDLINE, HEPATITIS-C, GUIDELINES, law.invention, HEMORRHAGE, Randomized controlled trial, law, Internal medicine, hemic and lymphatic diseases, von Willebrand Factor, medicine, Von Willebrand disease, Humans, Hemostasis, Science & Technology, Factor VIII, Perioperative management, HEMOPHILIA, business.industry, Hematology, medicine.disease, EFFICACY, CONCENTRATE WILATE(R), REPLACEMENT, von Willebrand Diseases, Systematic review, Minor surgery, Tranexamic Acid, SAFETY, Observational study, Systematic Review, business, Life Sciences & Biomedicine, Tranexamic acid, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd494099ef149c6fd16e2c549032a9c5Test
http://europepmc.org/articles/PMC8753200Test

المؤلفون: Iris van Moort, Tim Preijers, Laura H Bukkems, Hendrika C A M Hazendonk, Johanna G van der Bom, Britta A P Laros-van Gorkom, Erik A M Beckers, Laurens Nieuwenhuizen, Felix J M van der Meer, Paula Ypma, Michiel Coppens, Karin Fijnvandraat, Roger E G Schutgens, Karina Meijer, Frank W G Leebeek, Ron A A Mathôt, Marjon H Cnossen, Marjon H. Cnossen, Frank W.G. Leebeek, Ron A.A. Mathôt, Marieke J.H.A. Kruip, Suzanne Polinder, Janske Lock, Hendrika C.A.M. Hazendonk, Iris Van Moort, Jessica M. Heijdra, Marie C.H.J. Goedhart, Wala Al Arashi, Nico C.B. De Jager, Laura H. Bukkems, Michael E. Cloesmeijer, Alexander Janssen, Rienk Y.J. Tamminga, Paul Brons, Saskia E.M. Schols, Jeroen C.J. Eikenboom, Felix J.M. Van der Meer, Roger E.G. Schutgens, Kathelijne Fischer, Karin P.M. Van Galen, Erik E.A.M. Beckers, Floor C.J.I. Heubel-Moenen, Mariëtte H.E. Driessens, Ineke Van Vliet, Peter W. Collins, Ri Liesner, Pratima Chowdary, Carolyn M. Millar, Dan Hart, David Keeling

المساهمون: Pediatrics, Hematology, Public Health, Internal Medicine, Graduate School, Pharmacy, Other Research, Vascular Medicine, ACS - Pulmonary hypertension & thrombosis, Paediatric Haematology, Amsterdam Reproduction & Development (AR&D), Amsterdam Gastroenterology Endocrinology Metabolism, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Interne Geneeskunde, MUMC+: MA Hematologie (9), RS: Carim - B01 Blood proteins & engineering

المصدر: The Lancet Haematology, 8(7), e492-e502. Lancet Publishing Group
Lancet. Haematology, 8(7), e492-e502. Lancet Publishing Group
Lancet Haematology, 8, e492-e502
Lancet Haematology, 8(7), E492-E502. ELSEVIER SCI LTD
The Lancet Haematology, 8(7), E492-E502. ELSEVIER SCI LTD
Lancet Haematology, 8, 7, pp. e492-e502

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, PROPHYLACTIC TREATMENT, CONTINUOUS-INFUSION, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Haemophilia A, Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], Haemophilia, Hemophilia A, Severity of Illness Index, Drug Administration Schedule, Perioperative Care, law.invention, 03 medical and health sciences, 0302 clinical medicine, AGE, Pharmacokinetics, Randomized controlled trial, STAGE, law, hemic and lymphatic diseases, Internal medicine, medicine, Humans, ASSAY, Dosing, Factor VIII, business.industry, Coagulants, Standard treatment, Hematology, Perioperative, Middle Aged, medicine.disease, Treatment Outcome, Elective Surgical Procedures, 030220 oncology & carcinogenesis, Open label, business, COSTS, 030215 immunology

وصف الملف: application/pdf

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http://www.scopus.com/inward/record.url?scp=85108329665&partnerID=8YFLogxKTest

المؤلفون: Hugo ten Cate, Moniek P.M. de Maat, Diederik W.J. Dippel, Samantha J. Donkel, Frank W.G. Leebeek, Karmen Pater

المساهمون: Hematology, Neurology, Interne Geneeskunde, MUMC+: HVC Trombosezorg (8), MUMC+: MA Alg Interne Geneeskunde (9), MUMC+: HVC Pieken Trombose (9), RS: Carim - B04 Clinical thrombosis and Haemostasis

المصدر: Thrombosis Research, 202, 139-144. Elsevier Ltd.
Thrombosis Research, 202, 139-144. Elsevier Science

مصطلحات موضوعية: Thrombin generation, medicine.medical_specialty, Percentile, Young, 030204 cardiovascular system & hematology, Logistic regression, Gastroenterology, HYPERCOAGULABILITY, PLATELET-RICH PLASMA, MECHANISMS, Brain Ischemia, Transient ischemic attack (TIA), 03 medical and health sciences, 0302 clinical medicine, Thrombin, Internal medicine, medicine, Humans, Prospective Studies, Young adult, THROMBOGRAM, Prospective cohort study, MUTATION, Ischemic Stroke, RISK, business.industry, ADULTS, Hematology, Odds ratio, medicine.disease, Confidence interval, Stroke, ATHEROSCLEROSIS, CARDIOVASCULAR-DISEASE, Case-Control Studies, 030220 oncology & carcinogenesis, business, Case-controls studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a2a6030cec741d8e15795103aee5f3Test
https://doi.org/10.1016/j.thromres.2021.03.028Test

المؤلفون: Jens van de Wouw, Daphne Merkus, Dirk J. Duncker, Frank W.G. Leebeek, Moniek P.M. de Maat, Oana Sorop, Ilkka Heinonen, Ferdows Atiq

المساهمون: Hematology, Cardiology

المصدر: Thrombosis and Haemostasis, 121(5), 676-686. Georg Thieme Verlag
Thrombosis and Haemostasis

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Swine, Hypercholesterolemia, Invited T&H Insights, 030204 cardiovascular system & hematology, Gastroenterology, Hemostatics, Diabetes Mellitus, Experimental, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Antigen, Von Willebrand factor, SDG 3 - Good Health and Well-being, law, Internal medicine, Diabetes mellitus, hemic and lymphatic diseases, von Willebrand Factor, medicine, Animals, Endothelial dysfunction, Factor VIII, biology, business.industry, Hematology, Atherosclerosis, Streptozotocin, medicine.disease, Pathophysiology, von Willebrand Diseases, 030104 developmental biology, Endocrinology, biology.protein, Swine, Miniature, Biomarker (medicine), Blood Coagulation Tests, Endothelium, Vascular, business, Biomarkers, Dyslipidemia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd0207de32a04cdb100cef7e69fd1dbTest
http://www.scopus.com/inward/record.url?scp=85099602895&partnerID=8YFLogxKTest

المؤلفون: Max W. F. van Spengler, Laura H. Bukkems, Ron A. A. Mathôt, Tim Preijers, Marjon H. Cnossen, Frank W.G. Leebeek

المساهمون: Pediatrics, Hematology, Graduate School, Pharmacy, Other Research, Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, 77(8), 1193-1200. Springer-Verlag
European journal of clinical pharmacology, 77(8), 1193-1200. Springer Verlag

مصطلحات موضوعية: Adult, Metabolic Clearance Rate, Once weekly, 030204 cardiovascular system & hematology, Pharmacology, Hemophilia B, Polyethylene Glycols, Factor IX, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, Pharmacology (medical), In patient, Dosing, Aged, business.industry, Body Weight, Age Factors, Area under the curve, Half-life, Human albumin, General Medicine, Middle Aged, Pharmacokinetics and Disposition, Delayed-Action Preparations, Comparative study, business, Monte Carlo Method, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db90802c517ab0964ff4f2d73cf9ec9Test
https://doi.org/10.1007/s00228-021-03111-2Test

المؤلفون: Annet Simons, Paul P. T. Brons, Frank W.G. Leebeek, Daniëlle Meijer, Selene C M Schoormans, Britta A P Laros-van Gorkom, Waander L. van Heerde, Sandy Krouwel, Laurens Nieuwenhuizen, Dominique P M S M Maas, Nicole M. A. Blijlevens, Saskia E M Schols, Ferdows Atiq

المساهمون: Hematology

المصدر: Journal of Thrombosis and Haemostasis, 20(2), 316-327. Wiley-Blackwell Publishing Ltd
Journal of Thrombosis and Haemostasis, 20, 2, pp. 316-327
Journal of Thrombosis and Haemostasis, 20, 316-327

مصطلحات موضوعية: medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, biology, business.industry, Mucocutaneous zone, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Hematology, Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], medicine.disease, Gastroenterology, Cancer development and immune defence Radboud Institute for Health Sciences [Radboudumc 2], Genotype-phenotype distinction, Von Willebrand factor, Antigen, Hemostasis, Internal medicine, hemic and lymphatic diseases, Genotype, medicine, biology.protein, Von Willebrand disease, business, Genotyping, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9], circulatory and respiratory physiology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cc08c282316528b8364c12e641bfeaTest
https://pure.eur.nl/en/publications/ddb294bc-b7d6-4300-b9b9-372b6bb0b800Test

المؤلفون: Veronica H. Flood, Jean M. Grow, Reem A. Mustafa, Michael Laffan, Susie Couper, Frank W.G. Leebeek, Angela C. Weyand, Mohamad A. Kalot, Romina Brignardello-Petersen, Alice Arapshian, Sarah H. O'Brien, Rezan Abdul-Kadir, Peter A. Kouides, Margareth C. Ozelo, Paula D. James, Michelle Lavin, Nedaa Husainat, Nathan T. Connell, Alberto Tosetto

المساهمون: Hematology

المصدر: Blood advances, 5(1), 301-325. American Society of Hematology
Blood Adv

مصطلحات موضوعية: medicine.medical_specialty, MEDLINE, Context (language use), 030204 cardiovascular system & hematology, Hemophilia A, 03 medical and health sciences, 0302 clinical medicine, Health care, medicine, Von Willebrand disease, Humans, Intensive care medicine, Desmopressin, Hemostasis, business.industry, Thrombosis, Hematology, Guideline, Venous Thromboembolism, medicine.disease, Bleeding diathesis, von Willebrand Diseases, Female, Implementation research, business, Clinical Guidelines, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c99528f1afb0863f86d4ce9182536dTest
https://doi.org/10.1182/bloodadvances.2020003264Test

المؤلفون: Eva N. Hamulyák, Saskia Middeldorp, Joost G. Daams, Bart J. Biemond, Frank W.G. Leebeek, Peter A. W. te Boekhorst, Mandy N. Lauw

المصدر: Blood Advances, 5, 113-121
Blood Advances, 5, 1, pp. 113-121
Blood Adv

مصطلحات موضوعية: medicine.medical_specialty, medicine.drug_class, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], 030204 cardiovascular system & hematology, Lower risk, law.invention, 03 medical and health sciences, 0302 clinical medicine, Fibrinolytic Agents, Randomized controlled trial, law, Neoplasms, Internal medicine, Antithrombotic, medicine, Humans, Myelofibrosis, Myeloproliferative Disorders, Essential thrombocythemia, business.industry, Anticoagulant, Anticoagulants, Thrombosis, Venous Thromboembolism, Hematology, medicine.disease, 030220 oncology & carcinogenesis, Meta-analysis, Systematic Review, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5e730cdbe6e594f65a5fc2f49a97b0Test
https://doi.org/10.1182/bloodadvances.2020003628Test

المؤلفون: Marjon H. Cnossen, Jessica M. Heijdra, Quincy Kieboom, Frank W.G. Leebeek, Nico C B de Jager, Marieke J. H. A. Kruip, Ron A. A. Mathôt

المساهمون: Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Pharmacy, ACS - Pulmonary hypertension & thrombosis, Hematology, Pediatrics

المصدر: Thrombosis and haemostasis, 120(10), 1407-1416. Schattauer GmbH
Thrombosis and Haemostasis, 120(10), 1407-1416. Georg Thieme Verlag

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Population, empirical PK, 030204 cardiovascular system & hematology, Models, Biological, Gastroenterology, Hemostatics, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Von Willebrand factor, Pharmacokinetics, Internal medicine, hemic and lymphatic diseases, von Willebrand Factor, medicine, Von Willebrand disease, Humans, Deamino Arginine Vasopressin, Dosing, desmopressin response, Child, Desmopressin, education, Aged, Volume of distribution, education.field_of_study, biology, business.industry, Hematology, Middle Aged, medicine.disease, Bioavailability, von Willebrand Diseases, 030104 developmental biology, Child, Preschool, biology.protein, Female, business, von Willebrand disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fe40dd543c5765c901bb870f73199bTest
http://www.scopus.com/inward/record.url?scp=85089861052&partnerID=8YFLogxKTest