نتائج البحث - "Driver mutation"

1

Ultra‐mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns

المؤلفون: Li-Dong Wang, Jianshan Mao, Weiting Ge, Hanguang Hu, Wen Cai, Dehao Wu, Wangxiong Hu, Shu Zheng

المصدر: Cancer Medicine

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Colorectal cancer, colorectal cancer, Genetic Heterogeneity, Young Adult, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Risk Factors, Internal medicine, Cancer genome, Biomarkers, Tumor, medicine, Humans, Genetic Predisposition to Disease, Radiology, Nuclear Medicine and imaging, Pooled data, Age of Onset, Poly-ADP-Ribose Binding Proteins, Aged, Neoplasm Staging, Original Research, Aged, 80 and over, business.industry, driver mutation, Early disease, Clinical Cancer Research, DNA Polymerase II, Middle Aged, medicine.disease, Phenotype, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, POLE, Cohort, Female, heterogeneity, Colorectal Neoplasms, clinical patterns, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f4213af4f9ceb6c9080d702e9c787fTest
https://doi.org/10.1002/cam4.3579Test

2

Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing

المؤلفون: Jun Ouyang, Weirong Fan, Xueli Zhang, Rong Zhang, Yuan Ren, Zhigang Zhang, Lining Cui, Tianjiao Luo, Fangliang Xing, Xuefeng Bai, Xin Xing, Huan Yi, Fengmian Wang, Cancan Zhang, Linyan Zhu, Qin Yang, Jianping Qiu, Pengcheng Jiang

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 399-430 (2020)

مصطلحات موضوعية: Oncology, 0301 basic medicine, Cancer Research, ARID1A, medicine.disease_cause, 0302 clinical medicine, Tumor Cells, Cultured, Exome sequencing, Ovarian clear cell carcinomas, Ovarian Neoplasms, Medical record, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Clear cell carcinoma, MAGEE1, Female, KRAS, Target sequencing, Adult, medicine.medical_specialty, Original article, Biology, Malignancy, lcsh:RC254-282, Chromatin remodeling, 03 medical and health sciences, Asian People, Internal medicine, Exome Sequencing, medicine, Biomarkers, Tumor, PTEN, Humans, PI3K/AKT/mTOR pathway, Aged, Retrospective Studies, business.industry, Whole exome sequencing, Cancer, Driver mutation, medicine.disease, 030104 developmental biology, Case-Control Studies, Mutation, Cancer research, biology.protein, business, Biomedical sciences, Adenocarcinoma, Clear Cell, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91d898e4feb659a83c42f0618a45b8dTest
http://europepmc.org/articles/PMC7341065Test

3

Highly accurate DNA-based detection and treatment results of MET exon 14 skipping mutations in lung cancer

المؤلفون: Thüsen J.H. von der, Melinda A. Pruis, A-M.C. Dingemans, Willemina R. R. Geurts-Giele, Isabelle C. Meijssen, W. Dinjens, Marthe S. Paats, Hendrikus J. Dubbink, Martijn P. Lolkema, Joachim G.J.V. Aerts

المساهمون: Medical Oncology, Pulmonary Medicine, Pathology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Pulmonologie, MUMC+: MA Med Staf Spec Longziekten (9)

المصدر: Lung Cancer, 140, 46-54. Elsevier Ireland Ltd

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Lung Neoplasms, medicine.medical_treatment, sarcomatoid carcinoma, amplification, medicine.disease_cause, Targeted therapy, Exon, 0302 clinical medicine, Non-small cell lung cancer, Carcinoma, Non-Small-Cell Lung, diagnostics, CRIZOTINIB, met exon 14 skipping, Aged, 80 and over, Mutation, High-Throughput Nucleotide Sequencing, DNA, Neoplasm, Exons, Middle Aged, Proto-Oncogene Proteins c-met, Amplicon, Prognosis, MET Exon 14 Skipping Mutation, Survival Rate, 030220 oncology & carcinogenesis, Female, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Resistance against cMET inhibition, INHIBITION, Adenocarcinoma of Lung, PATIENT, DNA sequencing, target, resistance, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Internal medicine, Next generation sequencing, met inhibitor, Biomarkers, Tumor, medicine, Humans, Lung cancer, Protein Kinase Inhibitors, Aged, Retrospective Studies, Crizotinib, Diagnostic Tests, Routine, business.industry, driver mutation, medicine.disease, 030104 developmental biology, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057efac93cf37bf55ac4d294f4b0aedfTest
https://doi.org/10.1016/j.lungcan.2019.11.010Test

4

EGFR and KRAS Mutations in Lung Parenchyma of Subjects With EGFR/KRAS Wild-Type Lung Adenocarcinoma

المؤلفون: María Teresa Rodrigo-Calvo, Roberto Chalela, Karys Khilzi, Beatriz Bellosillo, Raquel Longarón, Joaquim Gea, Albert Sánchez-Font, Jose Gregorio González-García, Clara Martín-Ontiyuelo, Víctor Curull

المصدر: Pathology and Oncology Research
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

مصطلحات موضوعية: Male, Cancer Research, Lung Neoplasms, 030204 cardiovascular system & hematology, medicine.disease_cause, EGFR–epidermal growth factor receptor, Exon, 0302 clinical medicine, adenocacinoma lung, Aged, 80 and over, 05 social sciences, General Medicine, Middle Aged, Brief Research Report, Prognosis, Primary tumor, ErbB Receptors, Society Journal Archive, medicine.anatomical_structure, Oncology, Adenocarcinoma, Female, KRAS, Adenocarcinoma of Lung, Pathology and Forensic Medicine, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0502 economics and business, Parenchyma, medicine, Biomarkers, Tumor, Humans, Parenchymal Tissue, Aged, EGFR-epidermal growth factor receptor, Lung, business.industry, driver mutation, Wild type, Driver mutation, medicine.disease, respiratory tract diseases, Case-Control Studies, Mutation, Cancer research, Adenocacinoma lung, 050211 marketing, business, Carcinogenesis, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c957cf5e27bfd158703fa17ee259ff12Test
https://ddd.uab.cat/record/248155Test

5

A case of advanced adenocarcinoma genetically confirmed with EGFR/BRAF co-mutation in both primary and metastatic lesions

المؤلفون: Yusuke Shinozaki, Kei Morikawa, Takeo Inoue, Masamichi Mineshita, Hiroki Nishine, Masahiro Iinuma

المصدر: Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 13 (2021)

مصطلحات موضوعية: Metastatic lesions, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Mutually exclusive events, EGFR-mutant lung cancer, BRAF-mutant lung cancer, Oncology, double driver mutation, Mutation (genetic algorithm), medicine, Cancer research, Adenocarcinoma, case report, business, Lung cancer, Gene, RC254-282

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a53351b576bc3509b18628d6be5682Test
http://europepmc.org/articles/PMC8544759Test

6

المؤلفون: Corina van den Hurk, Annemarie Becker-Commissaris, Vashti N. M. F. Tromp, Iris Walraven, Nicole E Billingy

المساهمون: Pulmonary medicine, Clinical pharmacology and pharmacy, CCA - Cancer Treatment and quality of life, Ophthalmology, APH - Quality of Care, APH - Aging & Later Life

المصدر: Cancers
Volume 13
Issue 17
Cancers, 13(17):4282. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 13, 17
Billingy, N E, Tromp, V N M F, van den Hurk, C J G, Becker-Commissaris, A & Walraven, I 2021, ' Health-Related Quality of Life and Survival in Metastasized Non-Small Cell Lung Cancer Patients with and without a Targetable Driver Mutation ', Cancers, vol. 13, no. 17, 4282 . https://doi.org/10.3390/cancers13174282Test
Cancers, Vol 13, Iss 4282, p 4282 (2021)
Cancers, 13

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5214ee4729ef478ba1c5e7c67ee702baTest

7

Synergic Crosstalk between Inflammation, Oxidative Stress, and Genomic Alterations in BCR–ABL-Negative Myeloproliferative Neoplasm

المؤلفون: Marco Casciaro, Giovanni Pioggia, Alessandro Tonacci, Alessandro Allegra, Caterina Musolino, Sebastiano Gangemi

المصدر: Antioxidants, Vol 9, Iss 1037, p 1037 (2020)
Antioxidants
Antioxidants 9 (2020). doi:10.3390/antiox9111037
info:cnr-pdr/source/autori:Alessandro Allegra; Giovanni Pioggia; Alessandro Tonacci; Marco Casciaro; Caterina Musolino; Sebastiano Gangemi/titolo:Synergic Crosstalk between Inflammation, Oxidative Stress, and Genomic Alterations in BCR-ABL-Negative Myeloproliferative Neoplasm/doi:10.3390%2Fantiox9111037/rivista:Antioxidants/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:9

مصطلحات موضوعية: 0301 basic medicine, Physiology, Clinical Biochemistry, Inflammation, myelofibrosis, Review, Biochemistry, myeloproliferative neoplasms, thrombotic complication, 03 medical and health sciences, 0302 clinical medicine, Polycythemia vera, polycythemia vera, Medicine, oxidative stress, Myelofibrosis, Molecular Biology, Driver mutation, Essential thrombocythemia, Myeloproliferative neoplasms, Oxidative stress, ROS, Thrombotic complication, Myeloproliferative neoplasm, Janus kinase 2, biology, essential thrombocythemia, business.industry, driver mutation, lcsh:RM1-950, Cell Biology, medicine.disease, Haematopoiesis, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, inflammation, 030220 oncology & carcinogenesis, Cancer research, biology.protein, medicine.symptom, Stem cell, business