Surrogate Markers of Cardiovascular Risk and Chronic Obstructive Pulmonary Disease: A Large Case-Controlled Study
| العنوان: | Surrogate Markers of Cardiovascular Risk and Chronic Obstructive Pulmonary Disease: A Large Case-Controlled Study |
|---|---|
| المؤلفون: | Marie Fisk, Carmel M. McEniery, Nichola Gale, Kaisa Mäki-Petäjä, Julia R. Forman, Margaret Munnery, Jean Woodcock-Smith, Joseph Cheriyan, Divya Mohan, Jonathan Fuld, Ruth Tal-Singer, Michael I. Polkey, John R. Cockcroft, Ian B. Wilkinson, Charlotte Bolton, Peter Calverley, David Lomas, William MacNee, Mellone Marchong, Bruce Miller, Sridevi Nagarajan, Zahid Dhakam, Stacey Hickson, Julia Howard, Barry McDonnell, Karen Miles, Maggie Munnery, Pawan Pusalkar, Christopher Retallick, Jane Smith, Edna Thomas, Sharon Wallace, Susannah Williams, null Yasmin |
| المساهمون: | Fisk, Marie [0000-0002-1292-7642], McEniery, Carmel [0000-0003-3636-0705], Cheriyan, Joseph [0000-0001-6921-1592], Fuld, Jonathan [0000-0003-1847-184X], Wilkinson, Ian [0000-0001-6598-9399], Apollo - University of Cambridge Repository |
| المصدر: | Hypertension (Dallas, Tex. : 1979) Hypertension Fisk, M, McEniery, C M, Gale, N, Mäki-Petäjä, K, Forman, J R, Munnery, M, Woodcock-smith, J, Cheriyan, J, Mohan, D, Fuld, J, Tal-singer, R, Polkey, M I, Cockcroft, J R, Wilkinson, I B 2018, ' Surrogate Markers of Cardiovascular Risk and Chronic Obstructive Pulmonary Disease : A Large Case-Controlled Study ', Hypertension, vol. 71, no. 3, pp. 499-506 . https://doi.org/10.1161/HYPERTENSIONAHA.117.10151Test |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, carotid intima-media thickness, Comorbidity, 030204 cardiovascular system & hematology, 1102 Cardiovascular Medicine And Haematology, Corrections, Risk Assessment, Severity of Illness Index, 03 medical and health sciences, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Sex Factors, Vascular Stiffness, Reference Values, Internal medicine, Internal Medicine, Medicine, pulse wave analysis, Humans, Risk factor, Pulse wave velocity, Aged, Retrospective Studies, business.industry, case-control studies, Incidence, Smoking, Case-control study, Age Factors, Hemodynamics, 1103 Clinical Sciences, Retrospective cohort study, Middle Aged, medicine.disease, United Kingdom, cardiovascular diseases, Respiratory Function Tests, Survival Rate, Cardiovascular System & Hematology, 030228 respiratory system, Arterial stiffness, Cardiology, Biomarker (medicine), Female, business, Body mass index, Biomarkers |
| الوصف: | Cardiovascular disease is a common comorbidity and cause of mortality in chronic obstructive pulmonary disease. A better understanding of mechanisms of cardiovascular risk in chronic obstructive pulmonary disease patients is needed to improve clinical outcomes. We hypothesized that such patients have increased arterial stiffness, wave reflections, and subclinical atherosclerosis compared with controls and that these findings would be independent of smoking status and other confounding factors. A total of 458 patients with a diagnosis of chronic obstructive pulmonary disease and 1657 controls (43% were current or ex-smokers) with no airflow limitation were matched for age, sex, and body mass index. All individuals underwent assessments of carotid–femoral (aortic) pulse wave velocity, augmentation index, and carotid intima–media thickness. The mean age of the cohort was 67±8 years and 58% were men. Patients with chronic obstructive pulmonary disease had increased aortic pulse wave velocity (9.95±2.54 versus 9.27±2.41 m/s; P P P |
| وصف الملف: | application/pdf |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518692d6422639f4616d0b58f3d55ac0Test https://www.repository.cam.ac.uk/handle/1810/271744Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....518692d6422639f4616d0b58f3d55ac0 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |