Determinant-Based Classification of Acute Pancreatitis Severity: An International Multidisciplinary Consultation
| العنوان: | Determinant-Based Classification of Acute Pancreatitis Severity: An International Multidisciplinary Consultation |
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| المؤلفون: | Grazyna Rydzewska, Antonio Velasco Guardado, Antonio López-Serrano, Reza Mofidi, Raffaele Pezzilli, Jean louis Frossard, Katalin Darvas, Zilvinas Dambrauskas, John Windsor, Marcel Machado, Dejan Radenkovic, Savio George Barreto, Manu Shankar-Hari, Arkadiusz Wysocki, Enrique De-Madaria, Tarkan Karakan, Damian Mole, Ernesto Cairoli, Pierluigi Di sebastiano, Mohammed Abu Hilal, Vanesa Bernal-Monterde, George Konstantinou, Orestis Ioannidis, ANDREW Gumbs, Gulbin Aygencel, Dimitrios Lytras, Suresh Chari, Jan De Waele, EDGAR YAN, José Ardengh, Eduardo Albéniz, ABEL ARROYO SANCHEZ, Kandasami Palayan, Panu Mentula |
| المساهمون: | BAŞARANOĞLU, METİN |
| المصدر: | Annals of Surgery, 256, 875-880 ANNALS OF SURGERY r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname Annals of Surgery, 256, 6, pp. 875-880 |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | medicine.medical_specialty, acute pancreatitis, business.industry, MEDLINE, severity, macromolecular substances, medicine.disease, Clinical trial, pancreatic necrosis, Clinical research, Conceptual framework, classification, pancreatic infectious complications, Multidisciplinary approach, Severity of illness, medicine, peripancreatic necrosis, Pancreatitis, Acute pancreatitis, Surgery, organ failure, Molecular gastro-enterology and hepatology [IGMD 2], Intensive care medicine, business |
| الوصف: | Item does not contain fulltext OBJECTIVE:: To develop a new international classification of acute pancreatitis severity on the basis of a sound conceptual framework, comprehensive review of published evidence, and worldwide consultation. BACKGROUND:: The Atlanta definitions of acute pancreatitis severity are ingrained in the lexicon of pancreatologists but suboptimal because these definitions are based on empiric description of occurrences that are merely associated with severity. METHODS:: A personal invitation to contribute to the development of a new international classification of acute pancreatitis severity was sent to all surgeons, gastroenterologists, internists, intensivists, and radiologists who are currently active in clinical research on acute pancreatitis. The invitation was not limited to members of certain associations or residents of certain countries. A global Web-based survey was conducted and a dedicated international symposium was organized to bring contributors from different disciplines together and discuss the concept and definitions. RESULT:: The new international classification is based on the actual local and systemic determinants of severity, rather than description of events that are correlated with severity. The local determinant relates to whether there is (peri)pancreatic necrosis or not, and if present, whether it is sterile or infected. The systemic determinant relates to whether there is organ failure or not, and if present, whether it is transient or persistent. The presence of one determinant can modify the effect of another such that the presence of both infected (peri)pancreatic necrosis and persistent organ failure have a greater effect on severity than either determinant alone. The derivation of a classification based on the above principles results in 4 categories of severity-mild, moderate, severe, and critical. CONCLUSIONS:: This classification is the result of a consultative process amongst pancreatologists from 49 countries spanning North America, South America, Europe, Asia, Oceania, and Africa. It provides a set of concise up-to-date definitions of all the main entities pertinent to classifying the severity of acute pancreatitis in clinical practice and research. This ensures that the determinant-based classification can be used in a uniform manner throughout the world. |
| تدمد: | 0003-4932 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60117fdeaf0300c9a225847f14a39857Test http://hdl.handle.net/2066/110846Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....60117fdeaf0300c9a225847f14a39857 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00034932 |
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