نتائج البحث - "Driver mutation"

1

Ultra‐mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns

المؤلفون: Li-Dong Wang, Jianshan Mao, Weiting Ge, Hanguang Hu, Wen Cai, Dehao Wu, Wangxiong Hu, Shu Zheng

المصدر: Cancer Medicine

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Colorectal cancer, colorectal cancer, Genetic Heterogeneity, Young Adult, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Risk Factors, Internal medicine, Cancer genome, Biomarkers, Tumor, medicine, Humans, Genetic Predisposition to Disease, Radiology, Nuclear Medicine and imaging, Pooled data, Age of Onset, Poly-ADP-Ribose Binding Proteins, Aged, Neoplasm Staging, Original Research, Aged, 80 and over, business.industry, driver mutation, Early disease, Clinical Cancer Research, DNA Polymerase II, Middle Aged, medicine.disease, Phenotype, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, POLE, Cohort, Female, heterogeneity, Colorectal Neoplasms, clinical patterns, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f4213af4f9ceb6c9080d702e9c787fTest
https://doi.org/10.1002/cam4.3579Test

2

Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing

المؤلفون: Jun Ouyang, Weirong Fan, Xueli Zhang, Rong Zhang, Yuan Ren, Zhigang Zhang, Lining Cui, Tianjiao Luo, Fangliang Xing, Xuefeng Bai, Xin Xing, Huan Yi, Fengmian Wang, Cancan Zhang, Linyan Zhu, Qin Yang, Jianping Qiu, Pengcheng Jiang

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 399-430 (2020)

مصطلحات موضوعية: Oncology, 0301 basic medicine, Cancer Research, ARID1A, medicine.disease_cause, 0302 clinical medicine, Tumor Cells, Cultured, Exome sequencing, Ovarian clear cell carcinomas, Ovarian Neoplasms, Medical record, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Clear cell carcinoma, MAGEE1, Female, KRAS, Target sequencing, Adult, medicine.medical_specialty, Original article, Biology, Malignancy, lcsh:RC254-282, Chromatin remodeling, 03 medical and health sciences, Asian People, Internal medicine, Exome Sequencing, medicine, Biomarkers, Tumor, PTEN, Humans, PI3K/AKT/mTOR pathway, Aged, Retrospective Studies, business.industry, Whole exome sequencing, Cancer, Driver mutation, medicine.disease, 030104 developmental biology, Case-Control Studies, Mutation, Cancer research, biology.protein, business, Biomedical sciences, Adenocarcinoma, Clear Cell, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91d898e4feb659a83c42f0618a45b8dTest
http://europepmc.org/articles/PMC7341065Test

3

Highly accurate DNA-based detection and treatment results of MET exon 14 skipping mutations in lung cancer

المؤلفون: Thüsen J.H. von der, Melinda A. Pruis, A-M.C. Dingemans, Willemina R. R. Geurts-Giele, Isabelle C. Meijssen, W. Dinjens, Marthe S. Paats, Hendrikus J. Dubbink, Martijn P. Lolkema, Joachim G.J.V. Aerts

المساهمون: Medical Oncology, Pulmonary Medicine, Pathology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Pulmonologie, MUMC+: MA Med Staf Spec Longziekten (9)

المصدر: Lung Cancer, 140, 46-54. Elsevier Ireland Ltd

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Lung Neoplasms, medicine.medical_treatment, sarcomatoid carcinoma, amplification, medicine.disease_cause, Targeted therapy, Exon, 0302 clinical medicine, Non-small cell lung cancer, Carcinoma, Non-Small-Cell Lung, diagnostics, CRIZOTINIB, met exon 14 skipping, Aged, 80 and over, Mutation, High-Throughput Nucleotide Sequencing, DNA, Neoplasm, Exons, Middle Aged, Proto-Oncogene Proteins c-met, Amplicon, Prognosis, MET Exon 14 Skipping Mutation, Survival Rate, 030220 oncology & carcinogenesis, Female, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Resistance against cMET inhibition, INHIBITION, Adenocarcinoma of Lung, PATIENT, DNA sequencing, target, resistance, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Internal medicine, Next generation sequencing, met inhibitor, Biomarkers, Tumor, medicine, Humans, Lung cancer, Protein Kinase Inhibitors, Aged, Retrospective Studies, Crizotinib, Diagnostic Tests, Routine, business.industry, driver mutation, medicine.disease, 030104 developmental biology, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057efac93cf37bf55ac4d294f4b0aedfTest
https://doi.org/10.1016/j.lungcan.2019.11.010Test

4

EGFR and KRAS Mutations in Lung Parenchyma of Subjects With EGFR/KRAS Wild-Type Lung Adenocarcinoma

المؤلفون: María Teresa Rodrigo-Calvo, Roberto Chalela, Karys Khilzi, Beatriz Bellosillo, Raquel Longarón, Joaquim Gea, Albert Sánchez-Font, Jose Gregorio González-García, Clara Martín-Ontiyuelo, Víctor Curull

المصدر: Pathology and Oncology Research
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

مصطلحات موضوعية: Male, Cancer Research, Lung Neoplasms, 030204 cardiovascular system & hematology, medicine.disease_cause, EGFR–epidermal growth factor receptor, Exon, 0302 clinical medicine, adenocacinoma lung, Aged, 80 and over, 05 social sciences, General Medicine, Middle Aged, Brief Research Report, Prognosis, Primary tumor, ErbB Receptors, Society Journal Archive, medicine.anatomical_structure, Oncology, Adenocarcinoma, Female, KRAS, Adenocarcinoma of Lung, Pathology and Forensic Medicine, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0502 economics and business, Parenchyma, medicine, Biomarkers, Tumor, Humans, Parenchymal Tissue, Aged, EGFR-epidermal growth factor receptor, Lung, business.industry, driver mutation, Wild type, Driver mutation, medicine.disease, respiratory tract diseases, Case-Control Studies, Mutation, Cancer research, Adenocacinoma lung, 050211 marketing, business, Carcinogenesis, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c957cf5e27bfd158703fa17ee259ff12Test
https://ddd.uab.cat/record/248155Test

5

Translating Evidence from Clonal Hematopoiesis to Cardiovascular Disease: A Systematic Review

المؤلفون: Luisa Marracino, Gianluca Campo, Francesca Fortini, Mauro Vaccarezza, Paola Rizzo, Francesco Vieceli Dalla Sega, Veronica Papa

المصدر: Journal of Clinical Medicine, Vol 9, Iss 2480, p 2480 (2020)
Journal of Clinical Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc2ca3e1d13d0a15bfe0a655e8cc014Test
http://hdl.handle.net/11392/2421786Test

6

Integrating genetic mutations and expression profiles for survival prediction of lung adenocarcinoma

المؤلفون: Xi Zhang, Yuping Luo, Donglai Chen, Siguang Li, Yueqiang Song

المصدر: Thoracic Cancer

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Adult, Male, medicine.medical_specialty, Adenocarcinoma of Lung, Transcriptome, histologic subtype, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genotype, medicine, Biomarkers, Tumor, Humans, Tumor node metastasis, Lung cancer, Gene, Aged, Neoplasm Staging, Proportional Hazards Models, Aged, 80 and over, Lung, business.industry, Gene Expression Profiling, Driver mutation, General Medicine, Original Articles, Middle Aged, medicine.disease, lung adenocarcinoma, Prognosis, Phenotype, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, gene expression, Adenocarcinoma, Original Article, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8db6c0cd83864a2a7ad51be0d2f7dbeTest
http://europepmc.org/articles/PMC6501026Test

7

Clinical significance of ≥ 50% PD‐L1 expression with the SP263 monoclonal antibody in non‐small cell lung cancer patients

المؤلفون: Changyuan Guo, Peng Song, Lei Guo, Xiuyun Liu, Shugeng Gao, Wenbin Li, Jianming Ying

المصدر: Thoracic Cancer
Thoracic Cancer, Vol 10, Iss 2, Pp 175-182 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Lung Neoplasms, Gastroenterology, B7-H1 Antigen, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Incidence (epidemiology), Antibodies, Monoclonal, General Medicine, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, ErbB Receptors, Survival Rate, Oncology, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Pd l1 expression, Original Article, Female, Non small cell, Pulmonary and Respiratory Medicine, non‐small cell lung cancer, Adult, medicine.medical_specialty, medicine.drug_class, Adenocarcinoma of Lung, Monoclonal antibody, lcsh:RC254-282, smoking, 03 medical and health sciences, Internal medicine, medicine, Biomarkers, Tumor, Humans, In patient, Clinical significance, Lung cancer, Aged, Retrospective Studies, business.industry, Driver mutation, Original Articles, medicine.disease, 030104 developmental biology, programmed death ligand 1, Mutation, business, Immunostaining, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0da44542a2adec12ac5f84b70fd22f0Test
http://europepmc.org/articles/PMC6360219Test

8

Immunotherapy Benefit in a Patient With Non-Small Cell Lung Cancer and a Rare BRAF Mutation

المؤلفون: Rebekah Rittberg, Gefei Qing, David E. Dawe, Susan Green, Shantanu Banerji

المصدر: Cureus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e89cba6181d2dfb3db8b4689576abdcTest
https://doi.org/10.7759/cureus.11224Test

9

Integration of Tumor Mutation Burden and PD-L1 Testing in Routine Laboratory Diagnostics in Non-Small Cell Lung Cancer

المؤلفون: Lukas C. Heukamp, Balázs Jóri, S. Schatz, Eva-Maria Willing, Matthias Kröger, Harry J.M. Groen, Linda Diehl, Stefanie Schmidt, Markus Falk, Hayat Oum El Kheir Ramdani, Frank Griesinger, Markus Tiemann, C. Wesseler, Roopika Menon, Petra Hoffknecht

المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: Cancers, 12(6):1685, 1-14. MDPI AG
Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1685, p 1685 (2020)

مصطلحات موضوعية: 0301 basic medicine, Oncology, PD-L1, Cancer Research, medicine.medical_specialty, tumor mutational burden, BLOCKADE, NEOANTIGENS, PHASE-1, medicine.disease_cause, lcsh:RC254-282, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, IMMUNOHISTOCHEMISTRY, Lung cancer, immuno-oncology, Mutation, biology, business.industry, driver mutation, Routine laboratory, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, routine diagnostics, OPEN-LABEL, EFFICACY, Immune checkpoint, respiratory tract diseases, lung cancer, 1ST-LINE TREATMENT, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, NIVOLUMAB PLUS IPILIMUMAB, Biomarker (medicine), Non small cell, Antibody, SENSITIVITY, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8ac4497f7a0a8ca98d267c72164bc1Test
https://research.rug.nl/en/publications/3f08a1fc-fe7c-4f77-9a0f-80bf8ce9b9c8Test

10

Pathologic subtype-defined prognosis is dependent on both tumor stage and status of oncogenic driver mutations in lung adenocarcinoma

المؤلفون: Jie Zhang, Bo Jin, Ying Li, Baohui Han, Yu Dong, Shichun Tu, Hong Peng, Jinchen Shao

المصدر: Oncotarget

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b070fe452e81d6e0d482e94516a0d5a7Test
http://europepmc.org/articles/PMC5669886Test

تنقيح النتائج