نتائج البحث - "Driver mutation"

1

Highly accurate DNA-based detection and treatment results of MET exon 14 skipping mutations in lung cancer

المؤلفون: Thüsen J.H. von der, Melinda A. Pruis, A-M.C. Dingemans, Willemina R. R. Geurts-Giele, Isabelle C. Meijssen, W. Dinjens, Marthe S. Paats, Hendrikus J. Dubbink, Martijn P. Lolkema, Joachim G.J.V. Aerts

المساهمون: Medical Oncology, Pulmonary Medicine, Pathology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Pulmonologie, MUMC+: MA Med Staf Spec Longziekten (9)

المصدر: Lung Cancer, 140, 46-54. Elsevier Ireland Ltd

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Lung Neoplasms, medicine.medical_treatment, sarcomatoid carcinoma, amplification, medicine.disease_cause, Targeted therapy, Exon, 0302 clinical medicine, Non-small cell lung cancer, Carcinoma, Non-Small-Cell Lung, diagnostics, CRIZOTINIB, met exon 14 skipping, Aged, 80 and over, Mutation, High-Throughput Nucleotide Sequencing, DNA, Neoplasm, Exons, Middle Aged, Proto-Oncogene Proteins c-met, Amplicon, Prognosis, MET Exon 14 Skipping Mutation, Survival Rate, 030220 oncology & carcinogenesis, Female, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Resistance against cMET inhibition, INHIBITION, Adenocarcinoma of Lung, PATIENT, DNA sequencing, target, resistance, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Internal medicine, Next generation sequencing, met inhibitor, Biomarkers, Tumor, medicine, Humans, Lung cancer, Protein Kinase Inhibitors, Aged, Retrospective Studies, Crizotinib, Diagnostic Tests, Routine, business.industry, driver mutation, medicine.disease, 030104 developmental biology, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057efac93cf37bf55ac4d294f4b0aedfTest
https://doi.org/10.1016/j.lungcan.2019.11.010Test

2

EGFR and KRAS Mutations in Lung Parenchyma of Subjects With EGFR/KRAS Wild-Type Lung Adenocarcinoma

المؤلفون: María Teresa Rodrigo-Calvo, Roberto Chalela, Karys Khilzi, Beatriz Bellosillo, Raquel Longarón, Joaquim Gea, Albert Sánchez-Font, Jose Gregorio González-García, Clara Martín-Ontiyuelo, Víctor Curull

المصدر: Pathology and Oncology Research
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

مصطلحات موضوعية: Male, Cancer Research, Lung Neoplasms, 030204 cardiovascular system & hematology, medicine.disease_cause, EGFR–epidermal growth factor receptor, Exon, 0302 clinical medicine, adenocacinoma lung, Aged, 80 and over, 05 social sciences, General Medicine, Middle Aged, Brief Research Report, Prognosis, Primary tumor, ErbB Receptors, Society Journal Archive, medicine.anatomical_structure, Oncology, Adenocarcinoma, Female, KRAS, Adenocarcinoma of Lung, Pathology and Forensic Medicine, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0502 economics and business, Parenchyma, medicine, Biomarkers, Tumor, Humans, Parenchymal Tissue, Aged, EGFR-epidermal growth factor receptor, Lung, business.industry, driver mutation, Wild type, Driver mutation, medicine.disease, respiratory tract diseases, Case-Control Studies, Mutation, Cancer research, Adenocacinoma lung, 050211 marketing, business, Carcinogenesis, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c957cf5e27bfd158703fa17ee259ff12Test
https://ddd.uab.cat/record/248155Test

3

Clinical significance of ≥ 50% PD‐L1 expression with the SP263 monoclonal antibody in non‐small cell lung cancer patients

المؤلفون: Changyuan Guo, Peng Song, Lei Guo, Xiuyun Liu, Shugeng Gao, Wenbin Li, Jianming Ying

المصدر: Thoracic Cancer
Thoracic Cancer, Vol 10, Iss 2, Pp 175-182 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Lung Neoplasms, Gastroenterology, B7-H1 Antigen, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Incidence (epidemiology), Antibodies, Monoclonal, General Medicine, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, ErbB Receptors, Survival Rate, Oncology, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Pd l1 expression, Original Article, Female, Non small cell, Pulmonary and Respiratory Medicine, non‐small cell lung cancer, Adult, medicine.medical_specialty, medicine.drug_class, Adenocarcinoma of Lung, Monoclonal antibody, lcsh:RC254-282, smoking, 03 medical and health sciences, Internal medicine, medicine, Biomarkers, Tumor, Humans, In patient, Clinical significance, Lung cancer, Aged, Retrospective Studies, business.industry, Driver mutation, Original Articles, medicine.disease, 030104 developmental biology, programmed death ligand 1, Mutation, business, Immunostaining, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0da44542a2adec12ac5f84b70fd22f0Test
http://europepmc.org/articles/PMC6360219Test

4

Optimal management of brain metastases in oncogenic-driven non-small cell lung cancer (NSCLC)

المؤلفون: Rebecca Tay, Carsten Nieder, Nicolaus Andratschke, Raffaele Califano, Johannes Kraft, Riccardo Soffietti, Matthias Guckenberger

المساهمون: University of Zurich, Andratschke, Nicolaus

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Carcinogenesis, medicine.medical_treatment, non-small cell lung cancer (NSCLC), 610 Medicine & health, Radiosurgery, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Non-small cell lung cancer, Carcinoma, Non-Small-Cell Lung, Internal medicine, medicine, Animals, Humans, 1306 Cancer Research, Non-Small-Cell Lung, Lung, business.industry, Brain Neoplasms, Melanoma, Carcinoma, Cancer, Brain metastases, Driver mutation, Oncogenes, medicine.disease, Prognosis, 10044 Clinic for Radiation Oncology, Optimal management, 030104 developmental biology, medicine.anatomical_structure, Increased risk, Phenotype, 2740 Pulmonary and Respiratory Medicine, 030220 oncology & carcinogenesis, 2730 Oncology, business

وصف الملف: 1-s2.0-S0169500218306949-main.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b8218556259360eb64e843bcca9a5bTest
http://hdl.handle.net/2318/1729420Test

5

Clinicopathologic Correlation With Expression of PD-L1 on Both Tumor Cells and Tumor-infiltrating Immune Cells in Patients With Non-Small Cell Lung Cancer

المؤلفون: Fan Zhang, Wenbin Li, Shugeng Gao, Peng Song, Lei Guo, Jianming Ying

المصدر: Journal of Immunotherapy (Hagerstown, Md. : 1997)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Adenosquamous carcinoma, Concordance, Immunology, Gastroenterology, B7-H1 Antigen, smoking, 03 medical and health sciences, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, tumor-infiltrating immune cells, Risk Factors, Internal medicine, PD-L1, Carcinoma, Non-Small-Cell Lung, Clinical Studies, Carcinoma, Biomarkers, Tumor, non–small cell lung cancer (NSCLC), Immunology and Allergy, Medicine, Humans, Lung cancer, Aged, Neoplasm Staging, Pharmacology, Aged, 80 and over, biology, business.industry, driver mutation, Middle Aged, programmed death-ligand 1 (PD-L1), medicine.disease, Immunohistochemistry, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, biology.protein, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Adenocarcinoma, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ebd70fe2598045e17ca1cc6549f62dTest
https://pubmed.ncbi.nlm.nih.gov/30407231Test

6

Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas

المؤلفون: Haiquan Chen, Rui Wang, Yihua Sun, Hang Li, Yunjian Pan, Yuan Li, Yang Zhang, Yiliang Zhang, Lei Shen, Haichuan Hu, Yongfu Yu

المصدر: Zhang, Y, Wang, R, Li, Y, Pan, Y, Hu, H, Zhang, Y, Li, H, Shen, L, Yu, Y, Sun, Y & Chen, H 2015, ' Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas ', Journal of Thoracic Oncology, vol. 10, no. 10, pp. 1444-50 . https://doi.org/10.1097/JTO.0000000000000626Test