Intercenter Differences in Bronchopulmonary Dysplasia or Death Among Very Low Birth Weight Infants
| العنوان: | Intercenter Differences in Bronchopulmonary Dysplasia or Death Among Very Low Birth Weight Infants |
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| المؤلفون: | Namasivayam, Ambalavanan, Michele, Walsh, Georgiy, Bobashev, Abhik, Das, Burton, Levine, Waldemar A, Carlo, Rosemary D, Higgins, JoAnn, Poulsen |
| المصدر: | Pediatrics. 127:e106-e116 |
| بيانات النشر: | American Academy of Pediatrics (AAP), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Pediatrics, Birth weight, Prenatal care, law.invention, Randomized controlled trial, law, medicine, Cluster Analysis, Humans, Infant, Very Low Birth Weight, Bronchopulmonary Dysplasia, business.industry, Obstetrics, Mortality rate, Infant, Newborn, Articles, Odds ratio, Models, Theoretical, medicine.disease, Low birth weight, Bronchopulmonary dysplasia, Predictive value of tests, Pediatrics, Perinatology and Child Health, Female, medicine.symptom, business |
| الوصف: | OBJECTIVES: To determine (1) the magnitude of clustering of bronchopulmonary dysplasia (36 weeks) or death (the outcome) across centers of the Eunice Kennedy Shriver National Institute of Child and Human Development National Research Network, (2) the infant-level variables associated with the outcome and estimate their clustering, and (3) the center-specific practices associated with the differences and build predictive models. METHODS: Data on neonates with a birth weight of RESULTS: In 2001–2004, clustering of bronchopulmonary dysplasia/death was significant (pairwise odds ratio: 1.3; P < .001) and increased in 2006 (pairwise odds ratio: 1.6; overall incidence: 52%; range across centers: 32%–74%); center rates were relatively stable over time. Variables that varied according to center and were associated with increased risk of outcome included lower body temperature at NICU admission, use of prophylactic indomethacin, specific drug therapy on day 1, and lack of endotracheal intubation. Center differences remained significant even after correction for clustered variables. CONCLUSION: Bronchopulmonary dysplasia/death rates demonstrated moderate clustering according to center. Clinical variables associated with the outcome were also clustered. Center differences after correction of clustered variables indicate presence of as-yet unmeasured center variables. |
| تدمد: | 1098-4275 0031-4005 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894c23fc8fe2bb80a8f9148e96386ae3Test https://doi.org/10.1542/peds.2010-0648Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....894c23fc8fe2bb80a8f9148e96386ae3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10984275 00314005 |
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