المؤلفون: McNeish, IA, Kondrashova, O, Topp, M, Nesic, K, Lieschke, E, Ho, G-Y, Harrell, MI, Zapparoli, GV, Hadley, A, Holian, R, Boehm, E, Heong, V, Sanij, E, Pearson, RB, Krais, JJ, Johnson, N, McNally, O, Ananda, S, Alsop, K, Hutt, KJ, Kaufmann, SH, Lin, KK, Harding, TC, Traficante, N, DeFazio, A, Bowtell, DD, Swisher, EM, Dobrovic, A, Wakefield, MJ, Scott, CL

المساهمون: Imperial College Healthcare NHS Trust- BRC Funding, Cancer Research UK

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, HOMOLOGOUS RECOMBINATION REPAIR, OLAPARIB MAINTENANCE THERAPY, SPORADIC BREAST-CANCER, POLYMERASE INHIBITORS, POLY(ADP-RIBOSE) POLYMERASE, PLATINUM RESPONSE, SOMATIC MUTATIONS, PROMOTER REGION, FALLOPIAN-TUBE, PHASE-2 TRIAL, Animals, Antineoplastic Agents, BRCA1 Protein, Cell Line, Tumor, Cisplatin, DNA Methylation, Female, Gene Dosage, Humans, Indoles, Kaplan-Meier Estimate, Mice, Inbred NOD, Knockout, SCID, Ovarian Neoplasms

العلاقة: Nature Communications; http://hdl.handle.net/10044/1/61797Test; https://dx.doi.org/10.1038/s41467-018-05564-zTest; RDB01; RG71079

الإتاحة: https://doi.org/10.1038/s41467-018-05564-zTest
http://hdl.handle.net/10044/1/61797Test

المؤلفون: Swisher, EM, Lin, KK, Oza, AM, Scott, CL, Giordano, H, Sun, J, Konecny, GE, Coleman, RL, Tinker, AV, O'Malley, DM, Kristeleit, RS, Ma, L, Bell-McGuinn, KM, Brenton, JD, Cragun, JM, Oaknin, A, Ray-Coquard, I, Harrell, MI, Mann, E, Kaufmann, SH, Floquet, A, Leary, A, Harding, TC, Goble, S, Maloney, L, Isaacson, J, Allen, AR, Rolfe, L, Yelensky, R, Raponi, M, McNeish, IA

المصدر: Lancet Oncology , 18 (1) pp. 75-87. (2017)

مصطلحات موضوعية: Aged, Antineoplastic Agents, BRCA1 Protein, BRCA2 Protein, Drug Resistance, Neoplasm, Fallopian Tube Neoplasms, Female, Follow-Up Studies, Germ-Line Mutation, Humans, Indoles, International Agencies, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Peritoneal Neoplasms, Platinum, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, Prognosis, Prospective Studies, Salvage Therapy, Survival Rate

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10049690/1/Kristeleit_ARIEL2_HRD_Manuscript_Lancet_Oncol_09Sep2016%28clean%29.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10049690Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10049690/1/Kristeleit_ARIEL2_HRD_Manuscript_Lancet_Oncol_09Sep2016%28clean%29.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10049690Test/

المؤلفون: Swisher, EM, Lin, KK, Oza, AM, Scott, CL, Giordano, H, Sun, J, Konecny, GE, Coleman, RL, Tinker, AV, O'Malley, DM, Kristeleit, RS, Ma, L, Bell-McGuinn, KM, Brenton, JD, Cragun, JM, Oaknin, A, Ray-Coquard, I, Harrell, MI, Mann, E, Kaufmann, SH, Floquet, A, Leary, A, Harding, TC, Goble, S, Maloney, L, Isaacson, J, Allen, AR, Rolfe, L, Yelensky, R, Raponi, M, McNeish, IA

المصدر: 87 ; 75

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology, HOMOLOGOUS RECOMBINATION DEFICIENCY, POLY(ADP-RIBOSE) POLYMERASE, GENOMIC LOSS, DNA-REPAIR, MUTANT-CELLS, CANCER, BREAST, HETEROZYGOSITY, OLAPARIB, TUMORS, Aged, Antineoplastic Agents, BRCA1 Protein, BRCA2 Protein, Carcinoma, Ovarian Epithelial, Drug Resistance, Neoplasm, Fallopian Tube Neoplasms, Female, Follow-Up Studies, Germ-Line Mutation, Humans, Indoles, International Agencies, Middle Aged, Neoplasm Recurrence

العلاقة: Lancet Oncology; http://hdl.handle.net/10044/1/54675Test

الإتاحة: https://doi.org/10.1016/s1470-2045Test(16)30559-9
http://hdl.handle.net/10044/1/54675Test