Drip, Ship, and On-Demand Endovascular Therapy for Acute Ischemic Stroke
| العنوان: | Drip, Ship, and On-Demand Endovascular Therapy for Acute Ischemic Stroke |
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| المؤلفون: | Joon-Tae Kim, Kang-Ho Choi, Myeong-Kyu Kim, Eun-Bin Lee, Ji-Sung Lee, Seung-Ho Kang, Man-Seok Park, Seong-Min Choi, B. Chae Kim, Woong Yoon, Seung-Han Lee, Ki-Hyun Cho |
| المصدر: | PLoS ONE, Vol 11, Iss 3, p e0150668 (2016) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, Critical Care and Emergency Medicine, medicine.medical_treatment, lcsh:Medicine, Cardiovascular Medicine, Severity of Illness Index, Vascular Medicine, Brain Ischemia, Diagnostic Radiology, Brain ischemia, 0302 clinical medicine, Risk Factors, Modified Rankin Scale, Medicine and Health Sciences, Medicine, Thrombolytic Therapy, 030212 general & internal medicine, Cardiovascular Imaging, lcsh:Science, Tomography, Stroke, Multidisciplinary, Radiology and Imaging, Endovascular Procedures, Angiography, Arteries, Thrombolysis, Middle Aged, Magnetic Resonance Imaging, Community hospital, Treatment Outcome, Carotid Arteries, Neurology, Female, Anatomy, Research Article, medicine.medical_specialty, Imaging Techniques, Death Rates, Cerebrovascular Diseases, Neuroimaging, Research and Analysis Methods, 03 medical and health sciences, Population Metrics, Diagnostic Medicine, Severity of illness, Humans, cardiovascular diseases, Aged, Retrospective Studies, Ischemic Stroke, Demography, Intracerebral hemorrhage, Population Biology, business.industry, lcsh:R, Biology and Life Sciences, Retrospective cohort study, medicine.disease, Computed Axial Tomography, Surgery, People and Places, Cardiovascular Anatomy, Blood Vessels, lcsh:Q, business, 030217 neurology & neurosurgery, Neuroscience |
| الوصف: | Background The “drip and ship” approach can facilitate an early initiation of intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) at community hospitals. New endovascular treatment modalities, such as stent retrieval, have further improved the rate of safe and successful recanalization. We assessed the clinical outcomes of on-demand endovascular therapy in patients with AIS who were transported to a comprehensive stroke center under the “drip and ship” paradigm. Methods This retrospective study evaluated prospectively registered patients with acute large vessel occlusions in the anterior circulation who underwent endovascular recanalization after IVT at our regional comprehensive stroke center between January 2011 and April 2014. Clinical outcomes and neuroradiological findings were compared between patients who received IVT at the center (direct visit, DV) and at a community hospital (drip and ship, DS). Results Baseline characteristics such as age, initial National Institutes of Health Stroke Scale (NIHSS) score, and risk factors for stroke were similar, and most patients underwent endovascular therapy with a Solitaire stent (81.9% vs. 89.3% for DV and DS, respectively, P = 0.55). The average initial NIHSS score was 12.15±4.1 (12.06 vs. 12.39 for DV and DS, respectively, P = 0.719). The proportions of long-term favorable outcomes (modified Rankin Scale score ≤2 at 90 days) and successful recanalization (Thrombolysis in Cerebral Ischemia score ≥2b) were not significantly different (P = 0.828 and 0.158, respectively). The mortality rates and occurrences of symptomatic intracerebral hemorrhage were not significantly different (P = 0.999 and 0.267, respectively). Conclusions The “drip and ship” approach with subsequent endovascular therapy is a feasible treatment concept for patients with acute large vessel occlusion in the anterior circulation that could help improve clinical outcomes in patients with AIS. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951b1fdc9f4f7e08344d9c8f31d8a2b3Test http://europepmc.org/articles/PMC4777434?pdf=renderTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....951b1fdc9f4f7e08344d9c8f31d8a2b3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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