المؤلفون: Gong-Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket R. Gupte, Ranen Aviner, Patrick G. Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette R. Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F. Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M. Thompson, Wah Chiu

المصدر: Nature communications, vol 14, iss 1

مصطلحات موضوعية: Neurons, Proteomics, Huntington's Disease, Huntingtin Protein, Multidisciplinary, Animal, Induced Pluripotent Stem Cells, Neurosciences, General Physics and Astronomy, General Chemistry, Neurodegenerative, Stem Cell Research, General Biochemistry, Genetics and Molecular Biology, Mitochondria, Brain Disorders, Mice, Huntington Disease, Phenotype, Rare Diseases, Orphan Drug, Artificial Intelligence, Disease Models, Neurological, Animals, Humans

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c64404d0da476045f534c77ca70608Test
https://escholarship.org/uc/item/8sk2g35qTest

المؤلفون: Fabio Macciardi, Maria Giulia Bacalini, Ricardo Miramontes, Alessio Boattini, Cristian Taccioli, Giorgia Modenini, Rond Malhas, Laura Anderlucci, Yuriy Gusev, Thomas J. Gross, Robert M. Padilla, Massimo S. Fiandaca, Elizabeth Head, Guia Guffanti, Howard J. Federoff, Mark Mapstone

المساهمون: Macciardi, Fabio, Giulia Bacalini, Maria, Miramontes, Ricardo, Boattini, Alessio, Taccioli, Cristian, Modenini, Giorgia, Malhas, Rond, Anderlucci, Laura, Gusev, Yuriy, Gross, Thomas J, Padilla, Robert M, Fiandaca, Massimo S, Head, Elizabeth, Guffanti, Guia, Federoff, Howard J, Mapstone, Mark

المصدر: GeroScience, vol 44, iss 3

مصطلحات موضوعية: Aging, Retroelements, Blood biomarker, Neurodegenerative, Alzheimer's Disease, Blood biomarkers, Transposable element, Alzheimer Disease, Machine learning, Acquired Cognitive Impairment, Genetics, Humans, 2.1 Biological and endogenous factors, Retrotransposon, Aetiology, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer disease, Gene expression, Retrotransposons, Transposable elements, Biomarker, Brain Disorders, Neurological, RNA, Dementia, Geriatrics and Gerontology, Biomarkers, Human

وصف الملف: ELETTRONICO; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fed4f439d67051ab58e6db668f22f0eTest
https://hdl.handle.net/11585/901672Test

المؤلفون: Ryan G. Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P. Gold, Jack C. Reidling, Guomei Tang, Miriam Adam, David K. Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M. Reyes-Ortiz, Alice Lau, Richard A. Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E. Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E. Goldman, Leslie M. Thompson

المصدر: Nature communications, vol 13, iss 1

مصطلحات موضوعية: Huntington's Disease, General Physics and Astronomy, Biotin, Mice, Transgenic, Nerve Tissue Proteins, Neurodegenerative, General Biochemistry, Genetics and Molecular Biology, Transgenic, Mice, Rare Diseases, Genetics, Solitary Nucleus, 2.1 Biological and endogenous factors, Animals, Humans, Thiamine, Aetiology, Multidisciplinary, Animal, Neurosciences, General Chemistry, Stem Cell Research, Brain Disorders, Oligodendroglia, Disease Models, Animal, Huntington Disease, Disease Models, Neurological, Dietary Supplements, Stem Cell Research - Nonembryonic - Non-Human

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f9948beef509831c9cf3152893e723Test
https://pubmed.ncbi.nlm.nih.gov/36543778Test

المؤلفون: Alice L. Lau, Whitney England, Ricardo Miramontes, Leslie M. Thompson, Anthony Q. Vu, Christie D. Fowler, Maurice A. Curtis, Sebastian Markmiller, Edward J. Wild, Robert C. Spitale, Ryan G. Lim, Thai B. Nguyen, Lauren M. Byrne, Isabella I Sanchez, Iliana Orellana, Richard Faull, Gene W. Yeo, Jack C. Reidling

المصدر: The Journal of clinical investigation, vol 131, iss 12
J Clin Invest

مصطلحات موضوعية: 0301 basic medicine, Male, Huntington's Disease, Huntingtin, Hippocampus, Neurodegenerative, Medical and Health Sciences, Mice, 0302 clinical medicine, Cortex (anatomy), 2.1 Biological and endogenous factors, Aetiology, Poly-ADP-Ribose Binding Proteins, Neurons, Chemistry, Neurodegeneration, General Medicine, Human brain, Cell biology, DNA-Binding Proteins, Protein Transport, medicine.anatomical_structure, Huntington Disease, RNA Recognition Motif Proteins, 030220 oncology & carcinogenesis, Neurological, Female, RNA Helicases, Research Article, Immunology, Prefrontal Cortex, Cytoplasmic Granules, 03 medical and health sciences, Stress granule, Rare Diseases, Huntington's disease, medicine, Genetics, Animals, Humans, DNA Helicases, Neurosciences, medicine.disease, Brain Disorders, MicroRNAs, 030104 developmental biology, Unfolded protein response, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81859de49807db73fa46ad9da74aac06Test
https://escholarship.org/uc/item/0g99m33jTest

المؤلفون: Eva L. Morozko, Charlene Smith-Geater, Alejandro Mas Monteys, Subrata Pradhan, Ryan G. Lim, Peter Langfelder, Marketta Kachemov, Jayesh A. Kulkarni, Josh Zaifman, Austin Hill, Jennifer T. Stocksdale, Pieter R. Cullis, Jie Wu, Joseph Ochaba, Ricardo Miramontes, Anirban Chakraborty, Tapas K. Hazra, Alice Lau, Sophie St-cyr, Iliana Orellana, Lexi Kopan, Keona Q. Wang, Sylvia Yeung, Blair R. Leavitt, Jack C. Reidling, X. William Yang, Joan S. Steffan, Beverly L. Davidson, Partha S. Sarkar, Leslie M. Thompson

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 4

مصطلحات موضوعية: Huntington's Disease, 0301 basic medicine, Male, DNA Repair, Transcription, Genetic, Mutant, SUMO protein, Neurodegenerative, Inbred C57BL, Transgenic, Mice, 0302 clinical medicine, DNA damage repair, 2.1 Biological and endogenous factors, Aetiology, RNA, Small Interfering, Induced pluripotent stem cell, Neurons, Gene knockdown, Huntingtin Protein, Multidisciplinary, Cell Differentiation, Protein Inhibitors of Activated STAT, Ubiquitin ligase, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Huntington Disease, Neurological, Small Ubiquitin-Related Modifier Proteins, Female, Transcription, Pluripotent Stem Cells, PIAS, DNA damage, 1.1 Normal biological development and functioning, Primary Cell Culture, Mice, Transgenic, Biology, Small Interfering, 03 medical and health sciences, Rare Diseases, Genetic, Huntington's disease, Underpinning research, Genetics, medicine, Animals, Humans, PNKP, Gene, Protein Processing, Animal, Post-Translational, Neurosciences, Sumoylation, Correction, DNA, Stem Cell Research, medicine.disease, Brain Disorders, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, DNA Repair Enzymes, SUMO, Disease Models, biology.protein, RNA, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38249a9a6accb8170577dc07adbd259Test
https://pubmed.ncbi.nlm.nih.gov/34341126Test

المؤلفون: Ernest Fraenkel, Brook T. Wassie, Ryan G. Lim, Miriam Adam, Iliana Orellana, Maxwell P. Gold, Ricardo Miramontes, Lexi Kopan, Jennifer Stocksdale, Jie Wu, Keona Q. Wang, Sarah Hernandez, Shona Joy, Leslie M. Thompson, Charlene Smith-Geater, Nicholas D. Allen, Paul J. Kemp

المصدر: Stem cell reports, vol 14, iss 3
Elsevier
Stem Cell Reports, Vol 14, Iss 3, Pp 406-419 (2020)
Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, Huntington's Disease, Neurodegenerative, Regenerative Medicine, Biochemistry, Epigenesis, Genetic, 0302 clinical medicine, Neural Stem Cells, Stem Cell Research - Nonembryonic - Human, 2.1 Biological and endogenous factors, Age of Onset, Aetiology, Induced pluripotent stem cell, lcsh:QH301-705.5, Wnt Signaling Pathway, Cells, Cultured, Neurons, education.field_of_study, lcsh:R5-920, Cultured, single-cell RNA-seq, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Neurogenesis, Cell Cycle, Wnt signaling pathway, Huntington's disease, Cell Differentiation, Neural stem cell, 3. Good health, Cell biology, Up-Regulation, Huntington Disease, 5.1 Pharmaceuticals, Neurological, Stem Cell Research - Nonembryonic - Non-Human, Development of treatments and therapeutic interventions, lcsh:Medicine (General), Adult, Cell type, adult-onset HD, induced pluripotent stem cells, Cells, medium spiny neurons, Population, Clinical Sciences, Huntingtons disease, Mitosis, Biology, Medium spiny neuron, Article, 03 medical and health sciences, Rare Diseases, Genetic, WNT signaling, Genetics, medicine, Humans, education, development, Stem Cell Research - Induced Pluripotent Stem Cell, Neurosciences, Cell Biology, medicine.disease, Stem Cell Research, Brain Disorders, Neostriatum, 030104 developmental biology, lcsh:Biology (General), nervous system, Biochemistry and Cell Biology, Transcriptome, 030217 neurology & neurosurgery, Developmental Biology, Transcription Factors, Epigenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d522021b0a3988edd552e29219c4d98Test