دورية أكاديمية

Safety and accuracy of frameless electromagnetic-navigated (AXIEMTM)-guided brain lesion biopsies: a large single-unit study.

التفاصيل البيبلوغرافية
العنوان: Safety and accuracy of frameless electromagnetic-navigated (AXIEMTM)-guided brain lesion biopsies: a large single-unit study.
المؤلفون: Giamouriadis, Anastasios1 (AUTHOR) agiamouriadis@nhs.net, Perera, Duranka2 (AUTHOR), Safdar, Afshan3 (AUTHOR), Vergani, Francesco1 (AUTHOR), Bhangoo, Ranjeev1 (AUTHOR), Gullan, Richard1 (AUTHOR), Ashkan, Keyoumars1 (AUTHOR)
المصدر: Acta Neurochirurgica. Dec2019, Vol. 161 Issue 12, p2587-2593. 7p. 2 Diagrams, 4 Charts, 1 Graph.
مصطلحات موضوعية: *BRAIN damage, *BRAIN tumors, *BIOPSY, *ELECTRONIC records, *ADVERSE health care events, *CHRONIC traumatic encephalopathy
مستخلص: Background: Brain biopsies are required to establish a definitive histological diagnosis for brain lesions that have been identified on imaging in order to guide further treatment for patients. Objective: Various navigation systems are in use but little up to date evidence is available regarding the safety and accuracy of a frameless, electromagnetic technique to target brain lesions. Methods: Data was collected retrospectively on all patients that had brain biopsies at our institution from 01/01/2010 to 31/12/2017. Operation notes, neuropathology reports, and clinical notes on electronic patient record were used to determine whether biopsy of adequate identifiable abnormal tissue was achieved, whether a definitive diagnosis was established, any adverse events occurred, and if a repeat biopsy was carried out. Results: Three hundred seventy-one AxiEM (Medtronic, Minneapolis, USA)-guided brain tumor biopsies were performed in this 8-year period. Three hundred forty-nine (94.07%) procedures provided definitive tissue diagnosis, 22 (5.93%) were non diagnostic; in 6 cases (1.62%), repeat biopsy was performed and adverse events which caused clinical compromise were observed in 4 patients (1.08%). Conclusions: The AxiEM is a fast, effective, and safe frameless and pinless neuronavigational system. It offers a high degree of accuracy required for the establishment of a definitive diagnosis, permitting optimal further treatment, and thus improving patient outcomes. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:00016268
DOI:10.1007/s00701-019-04093-y