التفاصيل البيبلوغرافية
العنوان:
O-GlcNAcylation Reduces Ischemia-Reperfusion–Induced Brain Injury
المؤلفون:
Khalid Iqbal , Zheng-Hong Qin , Qian Yu , Chun-ling Dai , Fei Liu , Cheng-Xin Gong , Yanxing Chen , Jin-hua Gu , Yang Zhao , Jian-Bin Ge , Jianhua Shi
المصدر:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
بيانات النشر:
Nature Publishing Group, 2017.
سنة النشر:
2017
مصطلحات موضوعية:
0301 basic medicine , medicine.medical_specialty , Glycosylation , Biopsy , Ischemia , Fluorescent Antibody Technique , lcsh:Medicine , Brain damage , Models, Biological , Article , Brain Ischemia , Animals, Genetically Modified , Brain ischemia , O glcnacylation , Mice , 03 medical and health sciences , 0302 clinical medicine , Polysaccharides , Internal medicine , medicine , Animals , Humans , cardiovascular diseases , lcsh:Science , Mice, Knockout , Neurons , Multidisciplinary , medicine.diagnostic_test , business.industry , lcsh:R , medicine.disease , Immunohistochemistry , Disease Models, Animal , 030104 developmental biology , Reperfusion Injury , Anesthesia , Cardiology , lcsh:Q , medicine.symptom , Cerebral damage , business , Protein Processing, Post-Translational , Reperfusion injury , 030217 neurology & neurosurgery
الوصف:
O-GlcNAcylation is a common posttranslational modification of nucleocytoplasmic proteins with β-N-acetylglucosamine (GlcNAc) and regulates numerous biological processes. By using mouse models of cerebral ischemia induced by permanent and transient middle cerebral artery occlusion (MCAO), we observed an initial elevation (~1.7-fold, 1–4 hours after ischemia) and then decline of O-GlcNAcylation during cerebral ischemia. We found that moderate increase (
اللغة:
English
تدمد:
2045-2322
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef04d1efbdd4353da59483ff91fbb78Test http://link.springer.com/article/10.1038/s41598-017-10635-0Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....3ef04d1efbdd4353da59483ff91fbb78
قاعدة البيانات:
OpenAIRE
