Ongoing neural oscillations influence behavior and sensory representations by suppressing neuronal excitability
| العنوان: | Ongoing neural oscillations influence behavior and sensory representations by suppressing neuronal excitability |
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| المؤلفون: | Iemi, L., Gwilliams, L., Samaha, J., Auksztulewicz, R., Cycowicz, Y., King, J., Nikulin, V., Thesen, T., Doyle, W., Devinsky, O., Schroeder, C., Melloni, L., Haegens, S. |
| المصدر: | NeuroImage, Vol 247, Iss, Pp 118746-(2022) NeuroImage, 247 NeuroImage |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Adult, Male, Alpha, Drug Resistant Epilepsy, Oscillations, Excitability, Cognitive Neuroscience, 350 000 Brain Rhythms, Decoding, Brain, Neurosciences. Biological psychiatry. Neuropsychiatry, Electroencephalography, Prestimulus, Brain Waves, Discrimination, Psychological, Neurology, Auditory Perception, Reaction Time, Visual Perception, Humans, Female, Longitudinal Studies, Reaction times, Photic Stimulation, RC321-571 |
| الوصف: | The ability to process and respond to external input is critical for adaptive behavior. Why, then, do neural and behavioral responses vary across repeated presentations of the same sensory input? Ongoing fluctuations of neuronal excitability are currently hypothesized to underlie the trial-by-trial variability in sensory processing. To test this, we capitalized on intracranial electrophysiology in neurosurgical patients performing an auditory discrimination task with visual cues: specifically, we examined the interaction between prestimulus alpha oscillations, excitability, task performance, and decoded neural stimulus representations. We found that strong prestimulus oscillations in the alpha+ band (i.e., alpha and neighboring frequencies), rather than the aperiodic signal, correlated with a low excitability state, indexed by reduced broadband high-frequency activity. This state was related to slower reaction times and reduced neural stimulus encoding strength. We propose that the alpha+ rhythm modulates excitability, thereby resulting in variability in behavior and sensory representations despite identical input. |
| وصف الملف: | application/pdf |
| تدمد: | 1053-8119 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b5dc5bb450269c35a9aaf65894d8f9Test https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/283827Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....61b5dc5bb450269c35a9aaf65894d8f9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10538119 |
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