المؤلفون: Carla Rodriguez-Mogeda, Sabela Rodríguez-Lorenzo, Jiji Attia, Jack van Horssen, Maarten E. Witte, Helga E. de Vries

المصدر: Rodriguez-Mogeda, C, Rodríguez-Lorenzo, S, Attia, J, van Horssen, J, Witte, M E & de Vries, H E 2022, ' Breaching Brain Barriers : B Cell Migration in Multiple Sclerosis ', Biomolecules, vol. 12, no. 6, 800 . https://doi.org/10.3390/biom12060800Test, https://doi.org/10.3390/biom12060800Test

مصطلحات موضوعية: Central Nervous System, Multiple Sclerosis, Blood-Brain Barrier, Cell Movement, Brain, Humans, Molecular Biology, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6cc0fa222899e1590b437346dc6f4fTest
https://research.vumc.nl/en/publications/c846483d-a96b-450c-9294-abcf5004080aTest

المؤلفون: Gijs Kooij, Jack van Horssen, Alexandre Prat, Ruud D. Fontijn, Elizabeth Gowing, Marc Charabati, Bert van het Hof, Imad Didouh, Helga E. de Vries, Dirk Geerts, Susanne M. A. van der Pol, Claudio Derada Troletti

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neurovascular Disorders, Hematology laboratory, Amsterdam Neuroscience - Neuroinfection & -inflammation, AII - Inflammatory diseases, ACS - Microcirculation, CCA - Cancer biology and immunology, Medical Biology

المصدر: Cell Death and Disease, Vol 10, Iss 2, Pp 1-13 (2019)
Cell Death and Disease, 10(2):45. Nature Publishing Group
Cell death & disease, 10(2). Nature Publishing Group
Derada Troletti, C, Fontijn, R D, Gowing, E, Charabati, M, van Het Hof, B, Didouh, I, van der Pol, S M A, Geerts, D, Prat, A, van Horssen, J, Kooij, G & de Vries, H E 2019, ' Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology ', Cell Death and Disease, vol. 10, no. 2, 45 . https://doi.org/10.1038/s41419-018-1294-2Test
Cell Death & Disease
Cell death & disease, 10(2):45. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Multiple Sclerosis, Immunology, Inflammation, Neuroprotection, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Downregulation and upregulation, Humans, Medicine, Epithelial–mesenchymal transition, lcsh:QH573-671, Cells, Cultured, business.industry, lcsh:Cytology, Multiple sclerosis, Mesenchymal stem cell, Brain, Endothelial Cells, Cell Biology, medicine.disease, Cell biology, Endothelial stem cell, 030104 developmental biology, SNAI1, medicine.symptom, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9de50a6066f1229083128ebde12736Test
http://link.springer.com/article/10.1038/s41419-018-1294-2Test

المؤلفون: Philip Scheltens, Charlotte E. Teunissen, Victor L. Thijssen, Ananya Chakraborty, Ruud D. Fontijn, Alwin Kamermans, Ed Aanhane, Bert van het Hof, Jack van Horssen, Kitty C. M. Castricum, Wiesje M. van der Flier, Helga E. de Vries

المساهمون: Molecular cell biology and Immunology, Medical oncology laboratory, Radiation Oncology, Neurology, Clinical chemistry, Amsterdam Neuroscience - Neurovascular Disorders, APH - Personalized Medicine, APH - Methodology, Epidemiology and Data Science, ACS - Microcirculation

المصدر: Chakraborty, A, Kamermans, A, van Het Hof, B, Castricum, K, Aanhane, E, van Horssen, J, Thijssen, V L, Scheltens, P, Teunissen, C E, Fontijn, R D, van der Flier, W M & de Vries, H E 2018, ' Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy ', Brain : a journal of neurology, vol. 141, no. 12, pp. 3377-3388 . https://doi.org/10.1093Test/brain/awy274
Brain : a journal of neurology, 141(12), 3377-3388

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Angiopoietin-like 4 Protein, Vascular Remodeling, Blood–brain barrier, Vascular remodelling in the embryo, Angiopoietin, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Angiopoietin-Like Protein 4, Humans, Medicine, Vascular dementia, Aged, Aged, 80 and over, business.industry, Brain, Endothelial Cells, Human brain, medicine.disease, Cell Hypoxia, Endothelial stem cell, Cerebral Amyloid Angiopathy, 030104 developmental biology, medicine.anatomical_structure, Astrocytes, Microvessels, Female, Neurology (clinical), Cerebral amyloid angiopathy, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b850238bc9029d2faf99131bddf794dTest
https://doi.org/10.1093Test/brain/awy274

المؤلفون: Elien Wouters, Dieter Lütjohann, Jerome J. A. Hendriks, Jeroen F. J. Bogie, Tim Vanmierlo, Jo Mailleux, Jack van Horssen

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Multiple Sclerosis, 24(3), 279-289. SAGE Publications Ltd
Mailleux, J, Vanmierlo, T, Bogie, J F, Wouters, E, Lütjohann, D, Hendriks, J J & van Horssen, J 2018, ' Active liver X receptor signaling in phagocytes in multiple sclerosis lesions ', Multiple Sclerosis, vol. 24, no. 3, pp. 279-289 . https://doi.org/10.1177/1352458517696595Test

مصطلحات موضوعية: 0301 basic medicine, Multiple Sclerosis, Phagocytosis, Tissue Banks, 03 medical and health sciences, Myelin, chemistry.chemical_compound, 0302 clinical medicine, polycyclic compounds, Humans, Medicine, Liver X receptor, Cells, Cultured, Myelin Sheath, Liver X Receptors, business.industry, Macrophages, Multiple sclerosis, Brain, demyelinating diseases, multiple sclerosis, myelin sheath, phagocytes, liver X receptor, 27-hydroxycholesterol, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Neurology, chemistry, Myelin sheath, Immunology, 27-Hydroxycholesterol, lipids (amino acids, peptides, and proteins), Neurology (clinical), business, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3544204d18edeb350d531f5059a31bTest
https://doi.org/10.1177/1352458517696595Test

المؤلفون: Merel Rijnsburger, Ananya Chakraborty, Jack van Horssen, Susanne M. A. van der Pol, Alwin Kamermans, Helga E. de Vries

المساهمون: Molecular cell biology and Immunology, ACS - Microcirculation, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Kamermans, A, Rijnsburger, M, Chakraborty, A, van der Pol, S, de Vries, H E & van Horssen, J 2019, ' Reduced angiopoietin-like 4 expression in multiple sclerosis lesions facilitates lipid uptake by phagocytes via modulation of lipoprotein-lipase activity ', Frontiers in Immunology, vol. 10, no. MAY, 950 . https://doi.org/10.3389/fimmu.2019.00950Test
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 10(MAY):950

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Adult, Male, Multiple Sclerosis, Phagocyte, Central nervous system, Immunology, Angiopoietin, 03 medical and health sciences, Myelin, 0302 clinical medicine, astrocyte, ANGPTL4, Cell Line, Tumor, medicine, Immunology and Allergy, Angiopoietin-Like Protein 4, Humans, Remyelination, Myelin Sheath, Aged, Original Research, Aged, 80 and over, Lipoprotein lipase, Phagocytes, Chemistry, Multiple sclerosis, Macrophages, angiopoietin-like 4, Brain, Middle Aged, medicine.disease, Lipid Metabolism, Cell biology, Lipoprotein Lipase, 030104 developmental biology, medicine.anatomical_structure, remyelination, lipoprotein-lipase, Female, lcsh:RC581-607, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6987cede47e908aea4ec1ed1b61df203Test
https://research.vumc.nl/en/publications/28d72115-5a11-429c-8392-29e7a172ecdfTest

المؤلفون: Mirjana Stancic, Hans-Joachim Gabius, Jack van Horssen, Tineke H. Pinxterhuis, Charlotte G. H. M. de Jong, Anne-Marie van Dam, Wia Baron

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Anatomy and neurosciences, Molecular Neuroscience and Ageing Research (MOLAR)

المصدر: Journal of Neuropathology and Experimental Neurology, 77(11), 1024-1038. Lippincott Williams and Wilkins
Journal of neuropathology and experimental neurology, 77(11), 1024-1038. Oxford University Press
de Jong, C G H M, Stancic, M, Pinxterhuis, T H, van Horssen, J, van Dam, A-M, Gabius, H-J & Baron, W 2018, ' Galectin-4, a Negative Regulator of Oligodendrocyte Differentiation, Is Persistently Present in Axons and Microglia/Macrophages in Multiple Sclerosis Lesions ', Journal of Neuropathology and Experimental Neurology, vol. 77, no. 11, pp. 1024-1038 . https://doi.org/10.1093/jnen/nly081Test

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Male, Time Factors, Galectin 4, MACROPHAGE ACTIVATION, MYELIN MEMBRANE FORMATION, Mice, 0302 clinical medicine, Lectins, Galectin-4, Axon, Cells, Cultured, Microglia, Oligodendrocytes, Experimental autoimmune encephalomyelitis, Microfilament Proteins, Brain, General Medicine, Cell biology, medicine.anatomical_structure, FYN KINASE, Neurology, CELL-ADHESION MOLECULE, Cytokines, Demyelination, SUGAR CODE, CNS DEMYELINATION, ANIMAL LECTINS, Monoamine Oxidase Inhibitors, Multiple Sclerosis, CNS demyelination, Central nervous system, INDUCED DEMYELINATION, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Cuprizone, medicine, otorhinolaryngologic diseases, Animals, RNA, Messenger, Remyelination, Multiple sclerosis, Macrophages, CENTRAL-NERVOUS-SYSTEM, Calcium-Binding Proteins, Oligodendrocyte differentiation, medicine.disease, Axons, Peptide Fragments, Rats, Mice, Inbred C57BL, stomatognathic diseases, Disease Models, Animal, 030104 developmental biology, nervous system, Gene Expression Regulation, Myelin-Oligodendrocyte Glycoprotein, HUMAN MICROGLIA, Neurology (clinical), 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232dcc2bf7c32e926eda55a32cccdb2dTest
https://pubmed.ncbi.nlm.nih.gov/30252090Test

المؤلفون: Jack van Horssen, Susanne M. A. van der Pol, Sandra Amor, Philip G. Nijland, Hervé Perron

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Pathology

المصدر: van Horssen, J, van der Pol, S, Nijland, P, Amor, S & Perron, H 2016, ' Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis ', Multiple Sclerosis and Related Disorders, vol. 8, pp. 11-18 . https://doi.org/10.1016/j.msard.2016.04.006Test
Multiple Sclerosis and Related Disorders, 8, 11-18. Elsevier

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Multiple Sclerosis, medicine.drug_class, viruses, Endogenous retrovirus, Monoclonal antibody, Lesion, 03 medical and health sciences, 0302 clinical medicine, Retrovirus, medicine, Humans, Aged, Aged, 80 and over, Microglia, biology, business.industry, Macrophages, Multiple sclerosis, Endogenous Retroviruses, Antibodies, Monoclonal, Brain, Gene Products, env, General Medicine, Middle Aged, medicine.disease, biology.organism_classification, Immunohistochemistry, 030104 developmental biology, medicine.anatomical_structure, Neurology, Astrocytes, Immunology, embryonic structures, Female, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9f9ccdb89b7f6eb1e274c1fcda3a4aTest

المؤلفون: Micha M.M. Wilhelmus, Benjamin Drukarch, Jamie L. Lim, Jack van Horssen, Helga E. de Vries, Jeroen J.M. Hoozemans

المساهمون: Molecular cell biology and Immunology, Anatomy and neurosciences, Pathology, NCA - neurodegeneration

المصدر: Archives of Toxicology, 88(10), 1773-1786. Springer Verlag
Lim, J L, Wilhelmus, M M M, de Vries, H E, Drukarch, B, Hoozemans, J J M & van Horssen, J 2014, ' Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases ', Archives of Toxicology, vol. 88, no. 10, pp. 1773-1786 . https://doi.org/10.1007/s00204-014-1338-zTest

مصطلحات موضوعية: Antioxidant, NF-E2-Related Factor 2, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Central nervous system, Disease, Biology, Toxicology, medicine.disease_cause, Antioxidants, medicine, Animals, Humans, Transcription factor, chemistry.chemical_classification, Reactive oxygen species, Mechanism (biology), Multiple sclerosis, Brain, Neurodegenerative Diseases, General Medicine, medicine.disease, Mitochondria, Disease Models, Animal, Oxidative Stress, medicine.anatomical_structure, chemistry, Immunology, Microglia, Reactive Oxygen Species, Neuroscience, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c3641d065bcaaedfdf64f6b1d521e7Test
https://doi.org/10.1007/s00204-014-1338-zTest

المؤلفون: Malika Bsibsi, Wouter H. Gerritsen, Inge R. Holtman, Johannes M. van Noort, Paul van der Valk, Peter J. Nacken, Sandra Amor, Laura A. N. Peferoen, Bart J. L. Eggen, Jack van Horssen, Maarten E. Witte

المساهمون: Molecular Neuroscience and Ageing Research (MOLAR), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), Pathology, Molecular cell biology and Immunology, NCA - Neuroinflamation

المصدر: Acta Neuropathologica, 128(2), 215-229. SPRINGER
Acta Neuropathologica, 128(2), 215-229. Springer Verlag
Bsibsi, M, Peferoen, L A N, Holtman, I R, Nacken, P J, Gerritsen, W H, Witte, M E, van Horssen, J, Eggen, B J L, van der Valk, P, Amor, S & van Noort, J M 2014, ' Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-gamma and alpha B-crystallin ', Acta Neuropathologica, vol. 128, no. 2, pp. 215-229 . https://doi.org/10.1007/s00401-014-1317-8Test

مصطلحات موضوعية: APPEARING WHITE-MATTER, EXPRESSION, medicine.medical_treatment, Interleukin-1beta, Biology, Chemokine CXCL9, DISEASE, Pathology and Forensic Medicine, Multiple sclerosis, IFN-gamma, Glycogen Synthase Kinase 3, Cellular and Molecular Neuroscience, medicine, Humans, CXCL10, Ubiquitins, Cells, Cultured, LESIONS, Microglia, INTERFERON-GAMMA, Interleukin-6, Tumor Necrosis Factor-alpha, HSPB5, HEAT-SHOCK, Macrophages, CENTRAL-NERVOUS-SYSTEM, Brain, alpha-Crystallin B Chain, medicine.disease, Interleukin-12, Chemokine CXCL11, Interleukin-10, Cell biology, Chemokine CXCL10, TLR2, Interleukin 10, CYTOKINE, medicine.anatomical_structure, Cytokine, Immunology, Interleukin 12, T-CELLS, OXIDATIVE DAMAGE, Tumor necrosis factor alpha, Neurology (clinical), Demyelination

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a3cb320cba3eeeaedfc2f86f8b4c07Test
https://doi.org/10.1007/s00401-014-1317-8Test

المؤلفون: Susanne M. A. van der Pol, Anna Carrano, Annemieke J.M. Rozemuller, Helga E. de Vries, Jack van Horssen, Jeroen J.M. Hoozemans, Gijs Kooij, Robert Veerhuis, Hripsime Snkhchyan

المساهمون: Pathology, Molecular cell biology and Immunology, Clinical chemistry, NCA - Neurobiology of mental health, NCA - neurodegeneration

المصدر: Carrano, A, Snkhchyan, H, Kooij, G, van der Pol, S, van Horssen, J, Veerhuis, R, Hoozemans, J J M, Rozemuller, A J M & de Vries, H E 2014, ' ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy ', Neurobiology of Aging, vol. 35, no. 3, pp. 565-575 . https://doi.org/10.1016/j.neurobiolaging.2013.09.015Test
Neurobiology of Aging, 35(3), 565-575. Elsevier Inc.

مصطلحات موضوعية: Male, Aging, medicine.medical_specialty, Pathology, Down-Regulation, Gene Expression, ATP-binding cassette transporter, Blood–brain barrier, Alzheimer Disease, Internal medicine, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, RNA, Messenger, Cells, Cultured, Aged, P-glycoprotein, Aged, 80 and over, Messenger RNA, Amyloid beta-Peptides, Clusterin, biology, General Neuroscience, Brain, Endothelial Cells, Transporter, medicine.disease, Peptide Fragments, Capillaries, Neoplasm Proteins, Cerebral Amyloid Angiopathy, Endocrinology, medicine.anatomical_structure, biology.protein, Biomarker (medicine), ATP-Binding Cassette Transporters, Female, Neurology (clinical), Cerebral amyloid angiopathy, Geriatrics and Gerontology, Biomarkers, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd79142a81b5af3d206e5b3cb2bdc058Test
https://doi.org/10.1016/j.neurobiolaging.2013.09.015Test