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1
المصدر: Leukemia Research. 39:371-379
مصطلحات موضوعية: Cancer Research, Indoles, Blotting, Western, Antineoplastic Agents, Apoptosis, Hydroxamic Acids, Article, Bortezomib, Lactones, chemistry.chemical_compound, Refractory, hemic and lymphatic diseases, Panobinostat, Tumor Cells, Cultured, medicine, Humans, Pyrroles, Multiple myeloma, Cell Proliferation, business.industry, Myeloid leukemia, Hematology, Flow Cytometry, medicine.disease, Boronic Acids, Drug Combinations, Leukemia, Myeloid, Acute, Oncology, chemistry, Drug Resistance, Neoplasm, Caspases, Pyrazines, Immunology, Cancer research, Proteasome inhibitor, DNA fragmentation, business, Proteasome Inhibitors, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8f26d4275c9b8beea2f448efb55571Test
https://doi.org/10.1016/j.leukres.2014.12.014Test -
2
المؤلفون: Xin Yan Pei, Yun Dai, Shuang Chen, Robert Z. Orlowski, Liang Zhou, Yun Leng, Richard J. Jones, Steven Grant, Maciej Kmieciak, Yu Zhang, Hui Lin
المصدر: Blood. 124:2687-2697
مصطلحات موضوعية: cells, Fluorescent Antibody Technique, Apoptosis, Mice, SCID, Hydroxamic Acids, Biochemistry, Bortezomib, Small hairpin RNA, immune system diseases, Mice, Inbred NOD, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Cells, Cultured, Mice, Knockout, Gene knockdown, Lymphoid Neoplasia, Bcl-2-Like Protein 11, hemic and immune systems, Hematology, Boronic Acids, Tumor Burden, Pyrazines, RNA Interference, biological phenomena, cell phenomena, and immunity, Multiple Myeloma, medicine.drug, Immunoblotting, Immunology, Biology, Downregulation and upregulation, Cell Line, Tumor, Proto-Oncogene Proteins, Autophagy, medicine, Animals, Humans, neoplasms, Membrane Proteins, Cell Biology, Xenograft Model Antitumor Assays, Molecular biology, Histone Deacetylase Inhibitors, Drug Resistance, Neoplasm, Cell culture, Cancer research, Histone deacetylase, Apoptosis Regulatory Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb906a6b85294c357a4a699ef6fac4eTest
https://doi.org/10.1182/blood-2014-03-564534Test -
3
المؤلفون: Donna M. Weber, Caimiao Wei, R. Eric Davis, Deborah J. Kuhn, Zuzana Berkova, Timothy Madden, Sheeba K. Thomas, Veerabhadran Baladandayuthapani, Robert Z. Orlowski, Richard Woessner, Michael Wang, Hua Wang, Chad C. Bjorklund, Richard J. Jones, Jatin J. Shah, Wencai Ma, Pei Lin
المصدر: Blood. 120:3260-3270
مصطلحات موضوعية: medicine.medical_treatment, Blotting, Western, Immunology, Antineoplastic Agents, Apoptosis, Enzyme-Linked Immunosorbent Assay, Mice, SCID, Pharmacology, Biochemistry, Receptor, IGF Type 1, Bortezomib, Mice, Paracrine signalling, Insulin-like growth factor, immune system diseases, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Animals, Humans, Insulin-Like Growth Factor I, Autocrine signalling, Receptor, Multiple myeloma, Cell Proliferation, Oligonucleotide Array Sequence Analysis, Lymphoid Neoplasia, biology, Cell growth, Gene Expression Profiling, Imidazoles, Drug Synergism, Cell Biology, Hematology, Flow Cytometry, medicine.disease, Boronic Acids, Xenograft Model Antitumor Assays, Survival Rate, Insulin receptor, Drug Resistance, Neoplasm, Pyrazines, biology.protein, Multiple Myeloma, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb1ec3310b35c2bd7d5caecbbfd8b34Test
https://doi.org/10.1182/blood-2011-10-386789Test -
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المؤلفون: Jatin J. Shah, Robert Z. Orlowski
المصدر: Leukemia. 23:1964-1979
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Antineoplastic Agents, Article, Bortezomib, Lactones, chemistry.chemical_compound, Chemosensitization, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Protease Inhibitors, Pyrroles, Multiple myeloma, Hematology, business.industry, medicine.disease, Boronic Acids, Carfilzomib, Proteasome, chemistry, Pyrazines, Immunology, Proteasome inhibitor, Multiple Myeloma, business, Oligopeptides, Salinosporamide A, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dbb635bcff79a2b7bb4d033728c302Test
https://doi.org/10.1038/leu.2009.173Test -
5
المؤلفون: William Riordan, Robert Z. Orlowski, Jason M. Collins, Anastasia Ivanova, Celeste Lindley, E. Claire Dees, Dixie Lee Esseltine, Frances A. Collichio, Lisa A. Carey, Bert H. O'Neil
المصدر: Cancer Chemotherapy and Pharmacology. 63:99-107
مصطلحات موضوعية: Adult, Male, Drug, Cancer Research, Maximum Tolerated Dose, Gastrointestinal Diseases, media_common.quotation_subject, Salvage therapy, Pharmacology, Toxicology, Article, Polyethylene Glycols, Bortezomib, Refractory, immune system diseases, Neoplasms, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Combined Modality Therapy, Pharmacology (medical), Doxorubicin, cardiovascular diseases, neoplasms, Fatigue, Aged, media_common, Salvage Therapy, Liposome, Dose-Response Relationship, Drug, business.industry, Middle Aged, Boronic Acids, Hematologic Diseases, Neoplasm Proteins, Treatment Outcome, Oncology, Pyrazines, Liposomes, Proteasome inhibitor, Female, business, Proteasome Inhibitors, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8c7f1a8847115f803de5c9f5b2ff84Test
https://doi.org/10.1007/s00280-008-0716-8Test -
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المؤلفون: Deborah J. Kuhn, Jeffrey A. Nemeth, Peter M. Voorhees, Mohamed H. Zaki, Robert Corringham, Sally A. Hunsucker, George W. Small, John S. Strader, Qing Chen, Robert Z. Orlowski
المصدر: Clinical Cancer Research. 13:6469-6478
مصطلحات موضوعية: STAT3 Transcription Factor, Cancer Research, Stromal cell, Myeloid, Cell, Antineoplastic Agents, Apoptosis, Bone Marrow Cells, DNA Fragmentation, Biology, Bortezomib, immune system diseases, hemic and lymphatic diseases, medicine, Humans, HSP70 Heat-Shock Proteins, Multiple myeloma, Interleukin-6, Antibodies, Monoclonal, medicine.disease, Boronic Acids, Gene Expression Regulation, Neoplastic, STAT1 Transcription Factor, medicine.anatomical_structure, Oncology, Proteasome, Drug Resistance, Neoplasm, Pyrazines, Proteasome inhibitor, Cancer research, Immunotherapy, Syndecan-1, Bone marrow, Multiple Myeloma, Signal Transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d80fcc7d270795afdc7ae89e3e0f8fTest
https://doi.org/10.1158/1078-0432.ccr-07-1293Test -
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المؤلفون: Sen H. Zhuang, Liang Xiu, Ivan Spicka, Jean Luc Harousseau, Tadeusz Robak, Pieter Sonneveld, Joan Bladé, Wayne Rackoff, Trilok V. Parekh, Andrew Spencer, Arnon Nagler, Alexander Suvorov, Jesús F. San Miguel, Zhilong Yuan, Robert Z. Orlowski, Heather J. Sutherland, Anna Dmoszynska, Roman Hájek, Noemi Horvath
المساهمون: Hematology
المصدر: Journal of Clinical Oncology, 25, 3892-3901. American Society of Clinical Oncology
مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Randomization, Combination therapy, Disease-Free Survival, Polyethylene Glycols, Bortezomib, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Doxorubicin, Survival rate, Multiple myeloma, Aged, Aged, 80 and over, business.industry, Incidence, Hazard ratio, Middle Aged, medicine.disease, Boronic Acids, Hematologic Diseases, Surgery, Regimen, Cardiovascular Diseases, Drug Resistance, Neoplasm, Pyrazines, Disease Progression, Female, Neoplasm Recurrence, Local, Multiple Myeloma, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4064f6874c5cbadfcd04e516972fe3d8Test
https://doi.org/10.1200/jco.2006.10.5460Test -
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المؤلفون: Robert Z. Orlowski, Peter M. Voorhees
المصدر: Annual Review of Pharmacology and Toxicology. 46:189-213
مصطلحات موضوعية: Proteasome Endopeptidase Complex, medicine.medical_treatment, Antineoplastic Agents, Toxicology, Bortezomib, Ubiquitin, Neoplasms, hemic and lymphatic diseases, Heat shock protein, medicine, Animals, Humans, Multiple myeloma, Pharmacology, Chemotherapy, biology, Cancer, medicine.disease, Boronic Acids, Cell Transformation, Neoplastic, Proteasome, Drug Resistance, Neoplasm, Pyrazines, Cancer research, Proteasome inhibitor, biology.protein, Proteasome Inhibitors, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f887002dcb90f3b28292980505a10e0Test
https://doi.org/10.1146/annurev.pharmtox.46.120604.141300Test -
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المؤلفون: Joan Bladé, Pieter Sonneveld, Jamie Cavenagh, Sagar Lonial, Heinz Ludwig, Jesús F. San Miguel, Robert Z. Orlowski, Axel Glasmacher, Mario Boccadoro, Sundar Jagannath
المساهمون: Hematology
المصدر: Oncologist, 11(1), 51-61. AlphaMed Press
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Combination therapy, Antineoplastic Agents, Bortezomib, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Adverse effect, Survival analysis, Multiple myeloma, Dexamethasone, Hematology, business.industry, Peripheral Nervous System Diseases, medicine.disease, Prognosis, Boronic Acids, Survival Analysis, Thrombocytopenia, Surgery, Pyrazines, Proteasome inhibitor, business, Multiple Myeloma, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aef65f164d7baa7d1663365fbc1b38aTest
https://hdl.handle.net/1765/75024Test -
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المؤلفون: Anastasia Ivanova, Beverly S. Mitchell, Marie Green, Anandhi R. Johri, Peter M. Voorhees, Hendrik W. van Deventer, Elizabeth G. Trehu, Dixie Lee Esseltine, Reynaldo Garcia, Fred J. Kudrik, Thomas C. Shea, Julian Adams, Don A. Gabriel, Celeste Lindley, Paul Jones, Melissa D. Hall, E. Claire Dees, Mary Jo Lehman, Robert Z. Orlowski, Tammy Allred, Susan Natoli, Jason M. Collins
المصدر: Blood. 105:3058-3065
مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Immunology, Neutropenia, Pharmacology, Biochemistry, Polyethylene Glycols, Bortezomib, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Protease Inhibitors, Doxorubicin, Multiple myeloma, Aged, Aged, 80 and over, Antibiotics, Antineoplastic, business.industry, Myeloid leukemia, Cell Biology, Hematology, Middle Aged, medicine.disease, Boronic Acids, Regimen, Treatment Outcome, Hematologic Neoplasms, Pyrazines, Liposomes, Proteasome inhibitor, Female, business, Proteasome Inhibitors, Febrile neutropenia, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be63e30634119a9aa1ae7c9cb6a37b5Test
https://doi.org/10.1182/blood-2004-07-2911Test