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المؤلفون: Frédéric Blanchard, Dominique Heymann, Anne-Laure Gamblin, Pierre Layrolle, Bénédicte Brounais-Le Royer, Jérôme Amiaud, Pierre J. Guihard, Audrey Renaud, Marie-Astrid Boutet, Martine Berreur, Françoise Rédini
المصدر: The American Journal of Pathology. 185:765-775
مصطلحات موضوعية: STAT3 Transcription Factor, medicine.medical_treatment, Osteoclasts, Core Binding Factor Alpha 1 Subunit, Oncostatin M, Bone healing, Bone resorption, Pathology and Forensic Medicine, Mice, Osteogenesis, medicine, Animals, Bone Resorption, STAT3, Cell Proliferation, Osteoblasts, Tibia, biology, Bone Injury, Chemistry, Macrophages, Receptors, Oncostatin M, Osteoblast, Alkaline Phosphatase, Cell biology, Cytokine, medicine.anatomical_structure, Intramembranous ossification, Immunology, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5764749150fcf1d3998f3e0d48168eTest
https://doi.org/10.1016/j.ajpath.2014.11.008Test -
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المؤلفون: Emmanuelle David, François Rédini, Bénédicte Brounais, Carl D. Richards, Frédéric Blanchard, Régis Brion, Joel Delecrin, Sylvie Chevalier, Dominique Heymann, Pierre J. Guihard, Yannic Danger, Hugues Gascan
المساهمون: Heymann, D, Physiopathologie des Adaptations Nutritionnelles (PhAN), Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), Cytokines : structure, signalisation et prolifération tumorale, Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'orthopédie-traumatologie, Centre hospitalier universitaire de Nantes (CHU Nantes), Center for Gene Therapeutics, Hamilton, McMaster University [Hamilton, Ontario], This work was supported by Inserm, le Ministère de la Recherche, and La Ligue Contre le Cancer (comité Grand Ouest). P.G. is a recipient from a fellowship from le Ministère de la Recherche., Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
المصدر: Stem Cells / Stem Cells (Miamisburg)
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 2012, 30 (4), pp.762-72. ⟨10.1002/stem.1040⟩مصطلحات موضوعية: Lipopolysaccharides, Male, MESH: Signal Transduction, Physiology, Endocrinology, Diabetes and Metabolism, Osteoimmunology, MESH: Bone Matrix, Bone Matrix, 02 engineering and technology, MESH: Monocytes, Leukemia Inhibitory Factor, Monocytes, Mice, 0302 clinical medicine, Osteogenesis, MESH: Animals, MESH: Osteogenesis, MESH: Aged, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, 0303 health sciences, MESH: Middle Aged, biology, MESH: Dinoprostone, Gene Transfer Techniques, Oncostatin M, MESH: Macrophage Activation, Cell Differentiation, MESH: Adenoviridae, Osteoblast, Middle Aged, 021001 nanoscience & nanotechnology, MESH: Gene Expression Regulation, Cell biology, Bone morphogenetic protein 7, medicine.anatomical_structure, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, 030220 oncology & carcinogenesis, Molecular Medicine, MESH: Cyclooxygenase 2, 0210 nano-technology, Signal Transduction, Adult, MESH: Cell Differentiation, medicine.medical_specialty, Histology, CD14, 0206 medical engineering, MESH: Gene Transfer Techniques, Bone morphogenetic protein, Dinoprostone, MESH: Calcification, Physiologic, Bone resorption, Adenoviridae, 03 medical and health sciences, Calcification, Physiologic, MESH: Mice, Inbred C57BL, Internal medicine, medicine, Animals, Humans, MESH: Mice, Aged, 030304 developmental biology, MESH: Humans, Interleukin-6, Monocyte, Mesenchymal Stem Cells, MESH: Adult, Cell Biology, Macrophage Activation, MESH: Leukemia Inhibitory Factor, MESH: Interleukin-6, 020601 biomedical engineering, MESH: Male, MESH: Oncostatin M, Mice, Inbred C57BL, MESH: Mesenchymal Stem Cells, Endocrinology, Gene Expression Regulation, Cyclooxygenase 2, biology.protein, MESH: Lipopolysaccharides, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ce0fba337e20ea2e2a96faaad0df86Test
https://doi.org/10.1002/stem.1040Test -
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المصدر: Joint Bone Spine. 77:201-205
مصطلحات موضوعية: biology, Interleukin-6, business.industry, Cellular differentiation, Osteoporosis, medicine.disease, Receptors, Interleukin-6, In vitro, Bone remodeling, Proinflammatory cytokine, Arthritis, Rheumatoid, Rheumatology, Synovial Cell, Rheumatoid arthritis, Immunology, medicine, biology.protein, Animals, Humans, Joints, Bone Resorption, business, Interleukin 6
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018ccac85d0b4937fb8c6779cdf8d3dcTest
https://doi.org/10.1016/j.jbspin.2010.03.002Test -
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المؤلفون: Frédéric Blanchard, Céline Chipoy
المصدر: Drug Discovery Today. 10:197-204
مصطلحات موضوعية: medicine.drug_class, Anti-Inflammatory Agents, Antineoplastic Agents, Bone Neoplasms, Pharmacology, Biology, Nitric Oxide, Proinflammatory cytokine, Drug Discovery, medicine, Animals, Humans, Bone Resorption, Mode of action, Transcription factor, Inflammation, Lupus erythematosus, Histone deacetylase inhibitor, medicine.disease, Histone Deacetylase Inhibitors, Rheumatoid arthritis, Cancer cell, Cancer research, Cytokines, Histone deacetylase, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937b2ced3494f2d0559c5854b4febc84Test
https://doi.org/10.1016/s1359-6446Test(04)03309-4 -
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المؤلفون: Frédéric Blanchard, Françoise Rédini, G. De Pinieux, Marie-Françoise Heymann, Dominique Heymann, Emmanuelle David, François Gouin
المساهمون: Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Trousseau, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Génétique, immunothérapie, chimie et cancer (GICC), UMR 6239 CNRS [2008-2011] (GICC UMR 6239 CNRS), Université de Tours-Centre National de la Recherche Scientifique (CNRS), Centre hospitalier universitaire de Nantes (CHU Nantes), This work was supported by La Ligue Contre Le Cancer. E. David received a fellowship from the Ministère de la Recherche., Heymann, D, Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Sarcoma
Sarcoma, Hindawi Publishing Corporation, 2011, 2011, pp.932451. ⟨10.1155/2011/932451⟩
Sarcoma, 2011, 2011, pp.932451. ⟨10.1155/2011/932451⟩
Sarcoma, Vol 2011 (2011)مصطلحات موضوعية: Pathology, medicine.medical_specialty, Article Subject, Niche, [SDV.CAN]Life Sciences [q-bio]/Cancer, Review Article, Drug resistance, Biology, lcsh:RC254-282, Bone resorption, 03 medical and health sciences, 0302 clinical medicine, [SDV.CAN] Life Sciences [q-bio]/Cancer, medicine, Radiology, Nuclear Medicine and imaging, 030304 developmental biology, 0303 health sciences, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Oncology, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, 030220 oncology & carcinogenesis, Cancer research, Stem cell, Chondrosarcoma
وصف الملف: application/pdf; text/xhtml
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6d7ee836300ca385912296b89852c5Test
https://www.hal.inserm.fr/inserm-00667904Test -
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المؤلفون: Françoise Rédini, Franck Verrecchia, Gatien Moriceau, Bérengère Gobin, Frédéric Blanchard, Dominique Heymann, François Gouin, Benjamin Ory
المساهمون: Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Massachusetts General Hospital Cancer Center, Harvard Medical School [Boston] (HMS), Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), Heymann, D
المصدر: Current Pharmaceutical Design
Current Pharmaceutical Design, Bentham Science Publishers, 2010, 16 (27), pp.2981-7مصطلحات موضوعية: Pathology, medicine.medical_specialty, MESH: Osteosarcoma, Angiogenesis, MESH: Diphosphonates, MESH: Giant Cell Tumor of Bone, Chondrosarcoma, Antineoplastic Agents, Bone Neoplasms, MESH: Drug Design, Bone resorption, MESH: Bone Density Conservation Agents, Drug Discovery, medicine, Animals, Humans, MESH: Animals, Giant Cell Tumor of Bone, Pharmacology, Osteosarcoma, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Humans, Bone Density Conservation Agents, Diphosphonates, business.industry, Cartilage, Cancer, MESH: Chondrosarcoma, medicine.disease, MESH: Bone Neoplasms, Radiography, medicine.anatomical_structure, Primary bone, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Drug Design, MESH: Antineoplastic Agents, Sarcoma, business, Giant-cell tumor of bone
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb58e8ce4a2f69580d207494d631bdeTest
https://www.hal.inserm.fr/inserm-00511241Test -
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المؤلفون: Emmanuelle David, Bénédicte Brounais, Frédéric Blanchard
المصدر: Bone Cancer ISBN: 9780123748959
مصطلحات موضوعية: Osteolysis, Bone cancer, In vivo, Immunology, medicine, biology.protein, Cancer, Interleukin, Biology, medicine.disease, Interleukin 6, Bone resorption, Bone remodeling
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::dcfb106d1a845ee4e9a1d299eb2b434bTest
https://doi.org/10.1016/b978-0-12-374895-9.00008-6Test -
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المصدر: Cytokinegrowth factor reviews. 20(1)
مصطلحات موضوعية: medicine.medical_specialty, MAP Kinase Signaling System, Endocrinology, Diabetes and Metabolism, Immunology, Bone morphogenetic protein 8A, Bone Neoplasms, Bone tissue, Bone morphogenetic protein 2, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Bone and Bones, Bone remodeling, Mice, Internal medicine, Bone cell, medicine, Immunology and Allergy, Animals, Humans, Bone Resorption, Cell Proliferation, Bone Development, Chemistry, Interleukin-6, Bone morphogenetic protein 7, Bone morphogenetic protein 6, Endocrinology, Bone morphogenetic protein 5, medicine.anatomical_structure, Multigene Family, Cancer research, Cytokines, Bone Remodeling
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5716b2e2d6ed274b4ba9507c48cc7a96Test
https://pubmed.ncbi.nlm.nih.gov/19038573Test -
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المؤلفون: Françoise Rédini, Carmen Ruiz, Frédéric Blanchard, Francois Lamoureux, Julie Rousseau, Dominique Heymann, Bénédicte Brounais
المصدر: Recent patents on anti-cancer drug discovery. 3(3)
مصطلحات موضوعية: musculoskeletal diseases, Cancer Research, medicine.medical_specialty, Osteolysis, Bone disease, Osteoclasts, Antineoplastic Agents, Bone Neoplasms, Bone resorption, Bone remodeling, Drug Delivery Systems, Osteoprotegerin, Osteoclast, Internal medicine, Drug Discovery, medicine, Cathepsin K, Humans, Pharmacology (medical), Bone Resorption, Osteoblasts, biology, Chemistry, Cell Differentiation, General Medicine, medicine.disease, Endocrinology, medicine.anatomical_structure, Oncology, RANKL, Cancer research, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963b6874766da838892dc9d55d0fb6aeTest
https://pubmed.ncbi.nlm.nih.gov/18991786Test -
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المؤلفون: Kanji Mori, Françoise Rédini, Séverine Battaglia, Frédéric Blanchard, Kosei Ando, Laurence Duplomb, Céline Charrier, Dominique Heymann, Leonard D. Shultz
المساهمون: Physiopathologie de la résorption osseuse et thérapie des tumeurs osseuses primitives, Université de Nantes (UN)-IFR26-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Orthopaedic Surgery, Shiga University of Medical Science, Pôle Biologie, The Jackson Laboratory [Bar Harbor] (JAX), This work was supported by INSERM, The Région des Pays de la Loire, by a grant from the West Committee of the Ligue Contre le Cancer and by NIH Cancer Core grant CA34196., Heymann, D
المصدر: Cancer Science
Cancer Science, 2008, 99 (11), pp.2170-6. ⟨10.1111/j.1349-7006.2008.00919.x⟩
Cancer Science, Wiley Open Access, 2008, 99 (11), pp.2170-6. ⟨10.1111/j.1349-7006.2008.00919.x⟩مصطلحات موضوعية: MESH: Signal Transduction, Cancer Research, MESH: Osteosarcoma, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Bone cell, MESH: Up-Regulation, MESH: Janus Kinases, MESH: Animals, Osteosarcoma, 0303 health sciences, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Culture Media, Conditioned, MESH: STAT3 Transcription Factor, General Medicine, MESH: Bone Neoplasms, Up-Regulation, Cell biology, Crosstalk (biology), Oncology, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, 030220 oncology & carcinogenesis, Signal transduction, Signal Transduction, STAT3 Transcription Factor, medicine.medical_specialty, MESH: Cell Line, Tumor, Bone Neoplasms, Biology, Article, Bone resorption, 03 medical and health sciences, Cell Line, Tumor, Internal medicine, MESH: Cell Proliferation, medicine, Animals, Protein kinase B, MESH: Mice, PI3K/AKT/mTOR pathway, Cell Proliferation, Janus Kinases, 030304 developmental biology, MESH: Osteoblasts, Osteoblasts, Cell growth, MESH: Proto-Oncogene Proteins c-akt, medicine.disease, Endocrinology, MESH: Phosphatidylinositol 3-Kinases, Culture Media, Conditioned, Proto-Oncogene Proteins c-akt
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39a818c83d11e17145b3b0fd8ce2db0Test
https://www.hal.inserm.fr/inserm-00667527/documentTest
