المؤلفون: Pierre Avril, Franck Duteille, Perrine Ridel, Marie-Françoise Heymann, Gonzague De Pinieux, Françoise Rédini, Frédéric Blanchard, Dominique Heymann, Valérie Trichet, Pierre Perrot

المساهمون: Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Equipe labellisée Ligue contre le Cancer, Service de Chirurgie Plastique et des Brulés [CHU Nantes], Centre hospitalier universitaire de Nantes (CHU Nantes), Service d’Anatomie et Cytologie Pathologiques [CHU Nantes], CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), This work was supported by INSERM, the 'Ligue Contre le Cancer' (Equipe Labellisée LIGUE 2012). Pierre Avril was a recipient of the 'Fédération Nationale Enfants et Santé' and the 'Société Française de lutte contre les Cancers et les leucémies de l’Enfant et de l’Adolescent.' Perrine Ridel, M.D., was a recipient of 'Institut national du Cancer.', Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), maurice, sandrine

المصدر: Plastic and Reconstructive Surgery
Plastic and Reconstructive Surgery, Lippincott, Williams & Wilkins, In press, 137 (3), pp.865-875. ⟨10.1097/01.prs.0000479989.88114.8b⟩

مصطلحات موضوعية: 0301 basic medicine, Mice, Nude, Bone Neoplasms, Injections, Intralesional, Transplantation, Autologous, Mice, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Animals, Humans, Cell Proliferation, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Osteosarcoma, Cell Cycle, 3. Good health, Disease Models, Animal, 030104 developmental biology, Adipose Tissue, Solubility, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Culture Media, Conditioned, 030220 oncology & carcinogenesis, Female, Surgery, Neoplasm Recurrence, Local

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd63c5120be919ebee2e76edbbfd24e5Test
https://doi.org/10.1097/01.prs.0000479989.88114.8bTest

المؤلفون: Alexandrine Luseau, Emmanuelle David, David Monderer, Ronan Le Bot, Marie-Françoise Heymann, François Gouin, Marine Biger, Françoise Rédini, Laurence Lode, Marc G. Denis, Dominique Heymann, Stéphanie Ponsolle, Amelie Bellec, Sylvain Bercegeay, Frédéric Blanchard, Soraya Saiagh, Philippe Piloquet

المصدر: Laboratory Investigation. 93:1100-1114

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, Pathology, medicine.medical_specialty, Biopsy, Cell, Chondrosarcoma, Mice, Nude, Antineoplastic Agents, Bone Neoplasms, Pathology and Forensic Medicine, Mice, Cell Line, Tumor, Tumor Cells, Cultured, medicine, Animals, Humans, Molecular Biology, Aged, biology, Gene Expression Profiling, Cartilage, Mesenchymal stem cell, CD44, General Medicine, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, Drug Resistance, Multiple, Transplantation, Disease Models, Animal, medicine.anatomical_structure, Drug Resistance, Neoplasm, Cell culture, Mutation, Cancer research, biology.protein, Osteosarcoma, Female, Neoplasm Grading, Chondrogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b34a56314271062804f4bda96364e4Test
https://doi.org/10.1038/labinvest.2013.101Test

المؤلفون: Pierre J. Guihard, Marie F. Heymann, Franck Tirode, Frédéric Blanchard, Karine Laud, Olivier Delattre, Emmanuelle David, Marc Baud'huin, Françoise Rédini, Dominique Heymann

المساهمون: Centre de recherche sur l'action politique de l'UNIL (CRAPUL), Université de Lausanne (UNIL), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de génétique et biologie des cancers (U830), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5), Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA), Equipe LIGUE Nationale Contre le Cancer 2012, Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Centre de Recherche en Sciences et Technologies de l'Information et de la Communication - EA 3804 (CRESTIC), Université de Reims Champagne-Ardenne (URCA), TIRODE, Franck, Université de Lausanne = University of Lausanne (UNIL), Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), Université Paris Descartes - Paris 5 (UPD5)-Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes)

المصدر: American Journal of Pathology
American Journal of Pathology, American Society for Investigative Pathology, 2012, 181 (5), pp.1782-1795. ⟨10.1016/j.ajpath.2012.07.023⟩
American Journal of Pathology, 2012, 181 (5), pp.1782-1795. ⟨10.1016/j.ajpath.2012.07.023⟩

مصطلحات موضوعية: Oncogene Proteins, Fusion, Cellular differentiation, medicine.medical_treatment, Leukemia inhibitory factor receptor, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Leukemia Inhibitory Factor, Mesoderm, Mice, 0302 clinical medicine, Cytokine Receptor gp130, Osteosarcoma, 0303 health sciences, Oncostatin M, Cell Differentiation, 030220 oncology & carcinogenesis, Intercellular Signaling Peptides and Proteins, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], STAT3 Transcription Factor, Receptors, OSM-LIF, Chondrosarcoma, Bone Neoplasms, [SDV.CAN]Life Sciences [q-bio]/Cancer, Sarcoma, Ewing, Biology, Models, Biological, Pathology and Forensic Medicine, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, [SDV.CAN] Life Sciences [q-bio]/Cancer, Cell Line, Tumor, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Neuroblastoma, medicine, Animals, Humans, Cell Proliferation, 030304 developmental biology, Proto-Oncogene Protein c-fli-1, Growth factor, fungi, Mesenchymal stem cell, Receptors, Oncostatin M, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, medicine.disease, Protein Subunits, biology.protein, Cancer research, RNA-Binding Protein EWS, Leukemia inhibitory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db5f46703ed075ef857b3fed6bedbbdTest
https://doi.org/10.1016/j.ajpath.2012.07.023Test

المؤلفون: Anne Moreau, François Gouin, Catherine Chevalier, Martial Masson, Jérôme Guicheux, Anne Riet, Dominique Heymann, I Guisle-Marsollier, B. Le Goff, Frédéric Blanchard, Jean J. Leger, Kanji Mori, Françoise Rédini, Martine Berreur

المصدر: The Journal of Pathology. 211:555-562

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, Adolescent, Cell, Bone Neoplasms, Pathology and Forensic Medicine, Osteoprotegerin, Cell Line, Tumor, medicine, Humans, RNA, Messenger, RNA, Neoplasm, Phosphorylation, Child, neoplasms, Aged, Aged, 80 and over, Osteosarcoma, Osteoblasts, Receptor Activator of Nuclear Factor-kappa B, biology, Reverse Transcriptase Polymerase Chain Reaction, RANK Ligand, Middle Aged, medicine.disease, Immunohistochemistry, Neoplasm Proteins, Cross-Sectional Studies, medicine.anatomical_structure, Cell culture, RANKL, Cancer research, biology.protein, Female, Sarcoma, Signal transduction, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9dbff0a0364832d0037a67bc86f0c0Test
https://doi.org/10.1002/path.2140Test

المؤلفون: Bérengère, Gobin, Marc Baud', Huin, François, Lamoureux, Benjamin, Ory, Céline, Charrier, Rachel, Lanel, Séverine, Battaglia, Françoise, Redini, Frédéric, Lezot, Frédéric, Blanchard, Dominique, Heymann

المساهمون: Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Equipe LIGUE Nationale Contre le Cancer 2012, Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Centre hospitalier universitaire de Nantes (CHU Nantes), Department of Oncology and Metabolism [Sheffield, UK], The University of Sheffield [Sheffield, U.K.]

المصدر: International Journal of Cancer
International Journal of Cancer, Wiley, 2015, 136 (4), pp.784-796. ⟨10.1002/ijc.29040⟩

مصطلحات موضوعية: Male, Osteoblasts, Mice, Nude, Osteoclasts, Bone Neoplasms, Drug Synergism, [SDV.CAN]Life Sciences [q-bio]/Cancer, Xenograft Model Antitumor Assays, PI3K, Tumor Burden, Mice, Inbred C57BL, Inhibitory Concentration 50, Thiazoles, vascularization, Cell Line, Tumor, osteosarcoma, Antineoplastic Combined Chemotherapy Protocols, osteoclast, mTOR, osteoblast, Animals, Humans, Female, Phosphoinositide-3 Kinase Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ab939e622b530751bf3265414ed26845Test
https://www.hal.inserm.fr/inserm-01644799Test

المؤلفون: Benjamin Ory, Séverine Battaglia, Dominique Heymann, François Gouin, Frédéric Blanchard, Françoise Rédini

المصدر: Molecular Pharmacology. 71:333-343

مصطلحات موضوعية: Programmed cell death, Cell cycle checkpoint, DNA damage, ENDOG, Bone Neoplasms, Biology, Zoledronic Acid, S Phase, Cell Line, Tumor, Animals, Humans, Pharmacology, Osteosarcoma, Endodeoxyribonucleases, Microscopy, Confocal, Bone Density Conservation Agents, Cell Death, Diphosphonates, Cell growth, Cell Cycle, Imidazoles, Apoptosis Inducing Factor, DNA, Neoplasm, G2-M DNA damage checkpoint, Rats, Protein Transport, Apoptosis, Cancer research, Molecular Medicine, Apoptosis-inducing factor, Tumor Suppressor Protein p53

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c66a97310dbc00fdc8d6cad5476f67Test
https://doi.org/10.1124/mol.106.028837Test

المؤلفون: Frédéric Blanchard, Céline Chipoy

المصدر: Drug Discovery Today. 10:197-204

مصطلحات موضوعية: medicine.drug_class, Anti-Inflammatory Agents, Antineoplastic Agents, Bone Neoplasms, Pharmacology, Biology, Nitric Oxide, Proinflammatory cytokine, Drug Discovery, medicine, Animals, Humans, Bone Resorption, Mode of action, Transcription factor, Inflammation, Lupus erythematosus, Histone deacetylase inhibitor, medicine.disease, Histone Deacetylase Inhibitors, Rheumatoid arthritis, Cancer cell, Cancer research, Cytokines, Histone deacetylase, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937b2ced3494f2d0559c5854b4febc84Test
https://doi.org/10.1016/s1359-6446Test(04)03309-4

المؤلفون: Paul Pilet, Benjamin Ory, Chiara Riganti, Séverine Battaglia, Jukka Mönkkönen, Marc G. Denis, Dominique Heymann, Gatien Moriceau, Régis Brion, L. Mitrofan, Leonard D. Shultz, Françoise Rédini, Frédéric Blanchard, Céline Charrier

المصدر: Cancer research. 70(24)

مصطلحات موضوعية: Male, bisphosphonate, Cancer Research, Pharmacology, Zoledronic Acid, Mice, 0302 clinical medicine, 0303 health sciences, Mice, Inbred C3H, Osteosarcoma, Bone Density Conservation Agents, Diphosphonates, TOR Serine-Threonine Kinases, Imidazoles, Drug Synergism, Cell cycle, 3. Good health, Oncology, 030220 oncology & carcinogenesis, mTOR, medicine.drug, musculoskeletal diseases, Protein Prenylation, Bone Neoplasms, Cell Growth Processes, Biology, Article, 03 medical and health sciences, osteosarcoma, rapamycin, drug resistance, Prenylation, Cell Line, Tumor, medicine, Animals, Humans, Everolimus, PI3K/AKT/mTOR pathway, 030304 developmental biology, Sirolimus, Cell growth, medicine.disease, Rats, Mice, Inbred C57BL, Zoledronic acid, Drug Resistance, Neoplasm, ras Proteins, Protein prenylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ee742b259f4984e88ae35d1c89c81eTest
https://pubmed.ncbi.nlm.nih.gov/20971812Test

المؤلفون: Françoise Rédini, Franck Verrecchia, Gatien Moriceau, Bérengère Gobin, Frédéric Blanchard, Dominique Heymann, François Gouin, Benjamin Ory

المساهمون: Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Massachusetts General Hospital Cancer Center, Harvard Medical School [Boston] (HMS), Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), Heymann, D

المصدر: Current Pharmaceutical Design
Current Pharmaceutical Design, Bentham Science Publishers, 2010, 16 (27), pp.2981-7

مصطلحات موضوعية: Pathology, medicine.medical_specialty, MESH: Osteosarcoma, Angiogenesis, MESH: Diphosphonates, MESH: Giant Cell Tumor of Bone, Chondrosarcoma, Antineoplastic Agents, Bone Neoplasms, MESH: Drug Design, Bone resorption, MESH: Bone Density Conservation Agents, Drug Discovery, medicine, Animals, Humans, MESH: Animals, Giant Cell Tumor of Bone, Pharmacology, Osteosarcoma, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Humans, Bone Density Conservation Agents, Diphosphonates, business.industry, Cartilage, Cancer, MESH: Chondrosarcoma, medicine.disease, MESH: Bone Neoplasms, Radiography, medicine.anatomical_structure, Primary bone, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Drug Design, MESH: Antineoplastic Agents, Sarcoma, business, Giant-cell tumor of bone

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb58e8ce4a2f69580d207494d631bdeTest
https://www.hal.inserm.fr/inserm-00511241Test

المؤلفون: Laurence Duplomb, Frédéric Blanchard, Marc Baud'huin, Bénédicte Brounais

المصدر: Cytokinegrowth factor reviews. 20(1)

مصطلحات موضوعية: medicine.medical_specialty, MAP Kinase Signaling System, Endocrinology, Diabetes and Metabolism, Immunology, Bone morphogenetic protein 8A, Bone Neoplasms, Bone tissue, Bone morphogenetic protein 2, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Bone and Bones, Bone remodeling, Mice, Internal medicine, Bone cell, medicine, Immunology and Allergy, Animals, Humans, Bone Resorption, Cell Proliferation, Bone Development, Chemistry, Interleukin-6, Bone morphogenetic protein 7, Bone morphogenetic protein 6, Endocrinology, Bone morphogenetic protein 5, medicine.anatomical_structure, Multigene Family, Cancer research, Cytokines, Bone Remodeling

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5716b2e2d6ed274b4ba9507c48cc7a96Test
https://pubmed.ncbi.nlm.nih.gov/19038573Test