دورية أكاديمية
Difference in the Cytomegalovirus-related Clinical Laboratory Findings Between Patients With Bone Marrow and Kidney Transplantations
العنوان: | Difference in the Cytomegalovirus-related Clinical Laboratory Findings Between Patients With Bone Marrow and Kidney Transplantations |
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المؤلفون: | Misagh Rajabinejad, Ramin Lotfi, Seyed Askar Roghani, Elham Koolani, Bijan Soleymani, Alireza Rezaiemanesh, Zahra Mohamadi Kish, Behrooz Halashi, Ali Khorasanizadeh, Zhila Shaveisizadeh, Kamran Mansouri |
المصدر: | Research in Molecular Medicine, Vol 9, Iss 3, Pp 197-208 (2021) |
بيانات النشر: | Mazandaran University of Medical Sciences and Health Services, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Medicine (General) |
مصطلحات موضوعية: | cytomegalovirus, bone marrow transplantation, kidney transplantation, viral load, cyclosporine, Medicine (General), R5-920 |
الوصف: | Background: Despite close monitoring of transplant patients, Cytomegalovirus (CMV) infection has remained one of the most critical problems in transplantation. This study investigates the relationship between CMV viral load and clinical laboratory findings in transplant recipients. Materials And Methods: A total of 34 transplant recipients comprising 15 Kidney Transplant (KT) recipients and 19 Bone Marrow Transplant (BMT) recipients admitted to the Imam Reza Hospital in Kermanshah Province, Iran, were enrolled in this study. The CMV viral load was quantified by the real-time PCR technique. Results: The CMV viral load in KT recipients was significantly higher than in BMT recipients (P=0.03), and there was a positive association between the level of virus and the level of cyclosporine in the blood of patients (r=0.51, P=0.02). Besides, CMV viral load was positively correlated with WBC (r=0.32, P=0.04), urea (r=0.47, P=0.002), creatinine (r=0.39, P=0.01), aspartate aminotransferase (r=0.33, P=0.04), and lactate dehydrogenase (r=0.4, P=0.01). Also, it was negatively associated with albumin (r=-0.61, P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2322-1348 2322-133X |
العلاقة: | http://rmm.mazums.ac.ir/article-1-438-en.htmlTest; https://doaj.org/toc/2322-1348Test; https://doaj.org/toc/2322-133XTest |
الوصول الحر: | https://doaj.org/article/14a83539235f4daab791e270ae68e02dTest |
رقم الانضمام: | edsdoj.14a83539235f4daab791e270ae68e02d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 23221348 2322133X |
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