التفاصيل البيبلوغرافية
| العنوان: |
Obesity and lung cancer - is programmed death ligand-1 (PD-1L) expression a connection? |
| المؤلفون: |
Gałązka, Jakub Krzysztof, Czeczelewski, Marcin, Kucharczyk, Tomasz, Szklener, Katarzyna, Mańdziuk, Sławomir |
| المصدر: |
Archives of Medical Science; Jan2024, Vol. 20 Issue 1, p313-316, 4p |
| مصطلحات موضوعية: |
LUNG cancer, BODY mass index, OVERWEIGHT women, GAUSSIAN distribution, OBESITY |
| مستخلص: |
Introduction: In this retrospective study, the authors evaluated whether obesity-induced immunomodulation impacts the expression of programmed death ligand-1 (PD-1L) in lung cancer cells. Methods: A retrospective cross-sectional study was performed. The study included 67 patients. The data did not have a normal distribution. Results: For women, using ANOVA test (p = 0.050) with post-hoc analysis, a statistically significant difference in expression was found between women with overweight and women with normal weight (p = 0.040). Conclusions: Apart from the above, the authors did not find any statistically significant correlation between PD-1L expression on lung cancer cells and body mass index, either in the whole group or in histological subgroups. [ABSTRACT FROM AUTHOR] |
|
Copyright of Archives of Medical Science is the property of Termedia Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder