المؤلفون: John R. B. Perry, James B. Meigs, José Dupuis, Luigi Ferrucci, Johan G. Eriksson, Vilmundur Gudnason, Eric J.G. Sijbrands, Jeanette S. Andrews, Jonna L. Grimsby, Lawrence F. Bielak, Peter Kovacs, Panos Deloukas, Marijana Peričić, Johannes H. Smit, Ruth J. F. Loos, Gonneke Willemsen, Eric Boerwinkle, Ben A. Oostra, Manuel Serrano-Ríos, Alena Stančáková, Meena Kumari, Antti Jula, Michael Marmot, Caroline S. Fox, Simon Heath, Guo Li, Ola Hansson, Gerard Waeber, Anne U. Jackson, Nicholas L. Smith, Markku Laakso, George Dedoussis, Aarno Palotie, Sara M. Willems, John F. Peden, Elisabeth Widen, Caroline Hayward, Alan F. Wright, Claes Ladenvall, May E. Montasser, María Teresa Martínez-Larrad, Peter Vollenweider, Louis Pérusse, Tamara B. Harris, Wen Hong L. Kao, Danijela Budimir, Denis Rybin, David B. Savage, Michael A. Province, Alisa K. Manning, Bruna Gigante, Najaf Amin, Lenore J. Launer, Naveed Sattar, Lori L. Bonnycastle, Göran Hallmans, Jeffrey R. O'Connell, Stéphane Lobbens, Jacques S. Beckmann, Gemma Cadby, J. Wouter Jukema, Maria Dimitriou, Michael Stumvoll, Max Vikström, Rona J. Strawbridge, Hugh Watkins, Lyle J. Palmer, Johanna Kuusisto, Aimo Ruokonen, Hanieh Yaghootkar, Yan V. Sun, Inês Barroso, Amy J. Swift, Nancy L. Pedersen, Lars Lind, Mladen Boban, Nita G. Forouhi, Ken K. Ong, Ivana Kolcic, Anke Tönjes, Timothy M. Frayling, Paul W. Franks, Narisu Narisu, Karin Leander, Serge Hercberg, Diana Zelenika, Sharon L.R. Kardia, Min A. Jhun, Marjo-Riitta Järvelin, Stella Trompet, Jaakko Kaprio, Toshiko Tanaka, David S. Siscovick, Toby Johnson, Cornelia M. van Duijn, Veikko Salomaa, Jose C. Florez, James F. Wilson, Leena Peltonen, Pilar Galan, Robert Clarke, Andrew A. Hicks, Claudia Langenberg, Anders Hamsten, David Couper, Albert Hofman, Dawn M. Waterworth, John Blangero, James S. Pankow, Nabila Bouatia-Naji, Sirkka Keinänen-Kiukaanniemi, Mark I. McCarthy, Valeriya Lyssenko, Leif Groop, Brenda W.J.H. Penninx, Ching-Ti Liu, Anuj Goel, Marina Pehlić, Michael Boehnke, Mika Kivimäki, Maria Sabater-Lleal, Emil Rehnberg, Ingrid B. Borecki, Ozren Polasek, Eco J. C. de Geus, Peter P. Pramstaller, Igor Rudan, Richard M. Watanabe, Pierre Meneton, Iva Miljkovic, Vincent Mooser, G. Mark Lathrop, John Beilby, Laura J. Rasmussen-Torvik, Arturo Corbató-Anchuelo, Yvonne Böttcher, Richard N. Bergman, Daniel R. Barnes, Paul C. D. Johnson, Mustafa Atalay, Aroon D. Hingorani, Olga D. Carlson, Perttu Salo, Jacqueline C.M. Witteman, Udo Seedorf, Timo Saaristo, Jian'an Luan, Nicholas J. Wareham, Gudny Eiriksdottir, Matti Uusitupa, Yongmei Liu, Jaakko Tuomilehto, Yurii S. Aulchenko, Peter Schwarz, Robert A. Scott, Lina Zgaga, Joseph Hung, Reedik Mägi, Maria Grazia Franzosi, Eric J. Brunner, Claude Bouchard, Ian Ford, Francis S. Collins, Ulf de Faire, Benjamin F. Voight, Erik Ingelsson, Mario A. Morken, Stefania Bandinelli, Nicole L. Glazer, Dmitry Shungin, Lars Lannfelt, André G. Uitterlinden, Tatijana Zemunik, Markus Perola, Kenneth Rice, Veronique Vitart, Kerrin S. Small, Jouke-Jan Hottenga, Han Chen, Jerome I. Rotter, Philippe Froguel, Karen L. Mohlke, Marie-Claude Vohl, Dorret I. Boomsma, Harry Campbell, Peter S. Chines, Pau Navarro, Vasiliki Lagou, Albert V. Smith, Kathleen Stirrups, Josephine M. Egan, Alan R. Shuldiner, Katri Räikkönen, Inga Prokopenko, Ping An, Rainer Rauramaa, Beverley Balkau, Thor Aspelund, Eleanor Wheeler, Mariza de Andrade, Richa Saxena, Jari Lahti, Cécile Lecoeur, Timo A. Lakka, Jennie Hui, Michael R. Erdos, Stavroula Kanoni, Kirsten Ohm Kyvik, Bengt Sennblad, Sarah H. Wild, Patricia A. Peyser, Patrik K. E. Magnusson, Claire Bellis, Elodie Eury, Jaana Lindström

المساهمون: Boston University [Boston] (BU), Broad Institute of Harvard and MIT, Partenaires INRAE, Massachusetts General Hospital, Massachusetts General Hospital [Boston], Department of Genetics [Boston], Harvard Medical School [Boston] (HMS), Department of Medicine, Université de Sherbrooke (UdeS), Addenbrooke's Hospital, Harvard Medical School [Boston] (HMS)-Beth Israel Deaconess Medical Center [Boston] (BIDMC), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), Université Lille Nord de France (COMUE), Department of Epidemiology, University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System-Center for Social Epidemiology and Population Health, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford [Oxford], The Wellcome Trust Centre for Human Genetics [Oxford], The Netherlands Cancer Institute, Ontario Institute for Cancer Research, Mount Sinai Hospital [Toronto, Canada] (MSH), VU University Amsterdam, Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet [Stockholm], University of Michigan System, Queen Mary University of London (QMUL), The Wellcome Trust Sanger Institute [Cambridge], Lund University [Lund], Diabetes Centre, Lund University, University of Helsinki, Wake Forest School of Medicine, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, University of Maryland School of Medicine, University of Maryland System, University of Edinburgh, University of Exeter, Department of Twin Research and Genetic Epidemiology, King's College London, London, Northwestern University [Evanston], National Institute of Health and Welfare, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Lund University Diabetes Centre, Umeå University, National Institutes of Health, Centre for Medical Systems Biology, Netherlands Genomics Initiative, Washington University in Saint Louis (WUSTL), Department of Health Sciences Research, Mayo Clinic, Wake Forest University, Icelandic Heart Association, Heart Preventive Clinic and Research Institute, University of Iceland, Institute of Biomedicine, Physiology, University of Eastern Finland, Institut National de la Santé et de la Recherche Médicale (INSERM), UMR S 1018, Université Paris-Sud - Paris 11 (UP11), Azienda Sanitaria Firenze, Department of Medical Genetics, Université de Lausanne (UNIL), Centre Hospitalier Universitaire Vaudois (CHUV), Queen Elizabeth II Medical Centre, Research Institute, University of Southern California (USC), University of Split, The University of Texas Health Science Center at Houston (UTHealth), Leipzig University, Pennington Biomedical Research Center, Department of Epidemiology & Public Health, University College of London [London] (UCL), San Carlos Clinical Hospital, University of North Carolina, Harokopio University, National Institute on Aging, Folkhälsan Research Centre, Vaasa Central Hospital, Unité de Recherche en Epidémiologie Nutritionnelle (UREN), Université Paris 13 (UP13)-Institut National de la Recherche Agronomique (INRA)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Psychiatry, EMGO - Lifestyle, overweight and diabetes, Epidemiology, Immunology, Erasmus School of Social and Behavioural Sciences, Clinical Genetics, Ophthalmology, Internal Medicine, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Multiple Tissue Human Expression Resource (MUTHER) Consortium, Ahmadi, K.R., Ainali, C., Barrett, A., Bataille, V., Bell, J.T., Buil, A., Deloukas, P., Dermitzakis, E.T., Dimas, A.S., Durbin, R., Glass, D., Grundberg, E., Hassanali, N., Hedman, Å.K., Ingle, C., Knowles, D., Krestyaninova, M., Lindgren, C.M., Lowe, C.E., McCarthy, M.I., Meduri, E., di Meglio, P., Min, J.L., Montgomery, S.B., Nestle, F.O., Nica, A.C., Nisbet, J., O'Rahilly, S., Parts, L., Potter, S., Sekowska, M., Shin, S.Y., Small, K.S., Soranzo, N., Spector, T.D., Surdulescu, G., Travers, M.E., Tsaprouni, L., Tsoka, S., Wilk, A., Yang, T.P., Zondervan, K.T., Voight, B.F., Scott, L.J., Steinthorsdottir, V., Morris, A.P., Dina, C., Welch, R.P., Zeggini, E., Huth, C., Aulchenko, Y.S., Thorleifsson, G., McCulloch, L.J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C.J., Raychaudhuri, S., McCarroll, S.A., Langenberg, C., Hofmann, O.M., Dupuis, J., Qi, L., Segrè, A.V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A.J., Blagieva, R., Boerwinkle, E., Bonnycastle, L.L., Boström, K.B., Bravenboer, B., Bumpstead, S., Burtt, N.P., Charpentier, G., Chines, P.S., Cornelis, M., Couper, D.J., Crawford, G., Doney, A.S., Elliott, K.S., Elliott, A.L., Erdos, M.R., Fox, C.S., Franklin, C.S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C.J., Guiducci, C., Hadjadj, S., Herder, C., Isomaa, B., Jackson, A.U., Johnson, P.R., Jørgensen, T., Kao, W.H., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M.A., Narisu, N., Nilsson, P., Owen, K.R., Payne, F., Perry, J.R., Petersen, A.K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N.W., Robertson, N.R., Rocheleau, G., Roden, M., Sampson, M.J., Saxena, R., Shields, B.M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H.M., Sun, Q., Swift, A.J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R.M., van Haeften, T.W., van Herpt, T., van Vliet-Ostaptchouk, J.V., Walters, G.B., Weedon, M.N., Wijmenga, C., Witteman, J., Bergman, R.N., Cauchi, S., Collins, F.S., Gloyn, A.L., Gyllensten, U., Hansen, T., Hide, W.A., Hitman, G.A., Hofman, A., Hunter, D.J., Hveem, K., Laakso, M., Mohlke, K.L., Morris, A.D., Palmer, C.N., Pramstaller, P.P., Rudan, I., Sijbrands, E., Stein, L.D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N.J., Watanabe, R.M., Abecasis, G.R., Boehm, B.O., Campbell, H., Daly, M.J., Hattersley, A.T., Hu, F.B., Meigs, J.B., Pankow, J.S., Pedersen, O., Wichmann, H.E., Barroso, I., Florez, J.C., Frayling, T.M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J.F., Illig, T., Froguel, P., van Duijn, C.M., Stefansson, K., Altshuler, D., Boehnke, M., Biological Psychology, EMGO+ - Lifestyle, Overweight and Diabetes, Vrije universiteit = Free university of Amsterdam [Amsterdam] (VU), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Sorbonne Paris Cité (USPC)-Université Paris 13 (UP13)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut National de la Recherche Agronomique (INRA)

المصدر: Nature Genetics, 44(6), 659-669. Nature Publishing Group
Nature Genetics
Nature Genetics, Nature Publishing Group, 2012, 44 (6), pp.659-671. ⟨10.1038/ng.2274⟩
Manning, A K, Hivert, M-F, Scott, R A, Grimsby, J L, Bouatia-Naji, N, Chen, H, Rybin, D, Liu, C-T, Bielak, L F, Prokopenko, I, Amin, N, Barnes, D, Cadby, G, Hottenga, J-J, Ingelsson, E, Jackson, A U, Johnson, T, Kanoni, S, Ladenvall, C, Lagou, V, Lahti, J, Lecoeur, C, Liu, Y, Martinez-Larrad, M T, Montasser, M E, Navarro, P, Perry, J R B, Rasmussen-Torvik, L J, Salo, P, Sattar, N, Shungin, D, Strawbridge, R J, Tanaka, T, van Duijn, C M, An, P, de Andrade, M, Andrews, J S, Aspelund, T, Atalay, M, Aulchenko, Y, Balkau, B, Bandinelli, S, Campbell, H, Hayward, C, Rudan, I, Vitart, V, Wild, S H, Wilson, J F & Wright, A F & Zgaga, L 2012, ' A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance ', Nature Genetics, vol. 44, no. 6, pp. 659-U81 . https://doi.org/10.1038/ng.2274Test
Nature Genetics, 44(6), 659-U81. Nature Publishing Group
Nature Genetics; Vol 44
Nature genetics, vol. 44, no. 6, pp. 659-669
Manning, A K, Hivert, M F, Scott, R A, Grimsby, J L, Bouatia-Naji, N, Chen, H, Rybin, D, Liu, C T, Bielak, L F, Prokopenko, I, Amin, N, Barnes, D, Cadby, G, Hottenga, J J, Ingelsson, E, Boomsma, D I, de Geus, E J C, Penninx, B W J H, Willemsen, G, Wilson, J F, Witteman, J C M, Wright, A F, Yaghootkar, H, Zelenika, D, Zemunik, T, Zgaga, L, Wareham, N J, McCarthy, M I, Barroso, I, Watanabe, R M, Florez, J C, Dupuis, J, Meigs, J B & Langenberg, C 2012, ' A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance ', Nature Genetics, vol. 44, no. 6, pp. 659-669 . https://doi.org/10.1038/ng.2274Test
Manning, A K, Hivert, M-F, Scott, R A, Grimsby, J L, Bouatia-Naji, N, Chen, H, Rybin, D, Liu, C-T, Bielak, L F, Prokopenko, I, Amin, N, Barnes, D, Cadby, G, Hottenga, J-J, Ingelsson, E, Jackson, A U, Johnson, T, Kanoni, S, Ladenvall, C, Lagou, V, Lahti, J, Lecoeur, C, Liu, Y, Martinez-Larrad, M T, Montasser, M E, Navarro, P, Perry, J R B, Rasmussen-Torvik, L J, Salo, P, Sattar, N, Shungin, D, Strawbridge, R J, Tanaka, T, van Duijn, C M, An, P, de Andrade, M, Andrews, J S, Aspelund, T, Atalay, M, Aulchenko, Y, Balkau, B, Bandinelli, S, Beckmann, J S, Beilby, J P, Bellis, C, Bergman, R N, Blangero, J, Boban, M, Boehnke, M, Kyvik, K O & DIAGRAM Consortium 2012, ' A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance ', Nature Genetics, vol. 44, no. 6, pp. 659-669 . https://doi.org/10.1038/ng.2274Test
Nature Genetics, 44(6), 659-U81

مصطلحات موضوعية: Blood Glucose, Netherlands Twin Register (NTR), medicine.medical_treatment, [SDV]Life Sciences [q-bio], LOCI, Genome-wide association study, Type 2 diabetes, SUSCEPTIBILITY, Body Mass Index, GLUCOSE, Blood Glucose/metabolism, Cholesterol, HDL/metabolism, Diabetes Mellitus, Type 2/genetics, Genome-Wide Association Study, Humans, Insulin/metabolism, Insulin Resistance/genetics, Polymorphism, Single Nucleotide, 0302 clinical medicine, Insulin, 2. Zero hunger, Genetics, 0303 health sciences, COMMON VARIANTS, 3. Good health, ENVIRONMENT INTERACTION, OBESITY, CORONARY-ARTERY-DISEASE, medicine.medical_specialty, 030209 endocrinology & metabolism, Accounting, Biology, Article, 03 medical and health sciences, Insulin resistance, SDG 3 - Good Health and Well-being, Internal medicine, Diabetes mellitus, medicine, 030304 developmental biology, Genetic association, Glycemic, loci, SNP, insulin, business.industry, Cholesterol, HDL, medicine.disease, Obesity, POLYMORPHISM, ASSOCIATION ANALYSIS, Endocrinology, Diabetes Mellitus, Type 2, TYPE-2 DIABETES RISK, Insulin Resistance, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690ec4f28111d0636e4eb653c35f7bc2Test
https://doi.org/10.1038/ng.2274Test

المؤلفون: Daniel R. Witte, Han Chen, Lori L. Bonnycastle, Mette Aadahl, Olga D. Carlson, Josée Dupuis, Yii-Der Ida Chen, Tanya M. Teslovich, Richard M. Watanabe, Frida Renström, John W. Holloway, Meena Kumari, Michael Boehnke, Audrey Y. Chu, Robert A. Scott, Alisa K. Manning, Ajay Yesupriya, Anke Tönjes, Niels Grarup, Ingegerd Johansson, Nita G. Forouhi, Inês Barroso, Aroon D. Hingorani, Dmitry Shungin, Mika Kivimäki, Weijia Xie, David Couper, Diana Marek, Peter Schwarz, Torben Hansen, Jose C. Florez, Camilla H. Sandholt, Philippe Froguel, Leif Groop, Vasiliki Lagou, Johanna Kuusisto, W. H. Linda Kao, Suzannah Bumpstead, Nabila Bouatia-Naji, Inga Prokopenko, Peter Kovacs, Zoltán Kutalik, Eric Boerwinkle, Kenneth Rice, Michael R. Erdos, Gabriele Müller, Claire Levy-Marchal, Alena Stančáková, Jürgen Grässler, Erik Ingelsson, Mario A. Morken, Gerard Waeber, Eric J. Brunner, Ulf Ekelund, Luigi Ferrucci, Francis S. Collins, Mark Walker, Laura J. Rasmussen-Torvik, Markku Laakso, Stefan Gustafsson, Stefan R. Bornstein, Guo Li, Dan E. Arking, Torben Jørgensen, Peter Vollenweider, Peter Shrader, Michael Stumvoll, Mark O. Goodarzi, Oluf Pedersen, Avan Aihie Sayer, Heather M. Stringham, Bruce M. Psaty, Claudia Langenberg, Soren Brage, Ruth J. F. Loos, David S. Siscovick, Denis Rybin, Gordon H. Williams, Caroline S. Fox, Sven Bergmann, Felicity Payne, James B. Meigs, Marie-France Hivert, Nicole L. Glazer, Jerome I. Rotter, Elaine M. Dennison, Andrew R. Wood, Göran Hallmans, Nicole F. Dowling, Peter S. Chines, Cyrus Cooper, Josephine S. Egan, Paul W. Franks, Frank B. Hu, Michael Marmot, Pedro Marques-Vidal, Kari E. North, James S. Pankow, Valeri Lyssenko, Cécile Lecoeur, Toshiko Tanaka, Daniel R. Barnes, Nicholas J. Wareham, Anna Jonsson, Bo Isomaa, Anne U. Jackson, Karen A. Jameson

المساهمون: Barnes, Daniel [0000-0002-3781-7570], Brage, Soren [0000-0002-1265-7355], Forouhi, Nita [0000-0002-5041-248X], Barroso, Ines [0000-0001-5800-4520], Wareham, Nicholas [0000-0003-1422-2993], Langenberg, Claudia [0000-0002-5017-7344], Apollo - University of Cambridge Repository, Medical Research Council (MRC)

المصدر: Scott, R A, Chu, A Y, Grarup, N, Manning, A K, Hivert, M-F, Shungin, D, Tönjes, A, Yesupriya, A, Barnes, D, Bouatia-Naji, N, Glazer, N L, Jackson, A U, Kutalik, Z, Lagou, V, Marek, D, Rasmussen-Torvik, L J, Stringham, H M, Tanaka, T, Aadahl, M, Arking, D E, Bergmann, S, Boerwinkle, E, Bonnycastle, L L, Bornstein, S R, Brunner, E, Bumpstead, S J, Brage, S, Carlson, O D, Chen, H, Chen, Y-D I, Chines, P S, Collins, F S, Couper, D J, Dennison, E M, Dowling, N F, Egan, J S, Ekelund, U, Erdos, M R, Forouhi, N G, Fox, C S, Goodarzi, M O, Grässler, J, Gustafsson, S, Hallmans, G, Hansen, T, Hingorani, A, Holloway, J W, Hu, F B, Isomaa, B, Jameson, K A, Johansson, I, Jonsson, A, Jørgensen, T, Kivimaki, M, Kovacs, P, Kumari, M, Kuusisto, J, Laakso, M, Lecoeur, C, Lévy-Marchal, C, Li, G, Loos, R J F, Lyssenko, V, Marmot, M, Marques-Vidal, P, Morken, M A, Müller, G, North, K E, Pankow, J S, Payne, F, Prokopenko, I, Psaty, B M, Renström, F, Rice, K, Rotter, J I, Rybin, D, Sandholt, C H, Sayer, A A, Shrader, P, Schwarz, P E H, Siscovick, D S, Stancáková, A, Stumvoll, M, Teslovich, T M, Waeber, G, Williams, G H, Witte, D, Wood, A R, Xie, W, Boehnke, M, Cooper, C, Ferrucci, L, Froguel, P, Groop, L, Kao, W H L, Vollenweider, P, Walker, M, Watanabe, R M, Pedersen, O, Meigs, J B, Ingelsson, E, Barroso, I, Florez, J C, Franks, P W, Dupuis, J, Wareham, N J & Langenberg, C 2012, ' No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels ', Diabetes, vol. 61, no. 5, pp. 1291-6 . https://doi.org/10.2337/db11-0973Test
Diabetes
Diabetes; Vol 61

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, DIABETES PREVENTION PROGRAM, ENDOCRINOLOGY & METABOLISM, Genotype, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Physical exercise, Single-nucleotide polymorphism, PROGRESSION, Type 2 diabetes, Biology, Motor Activity, Polymorphism, Single Nucleotide, Body Mass Index, Epigenesis, Genetic, 03 medical and health sciences, TYPE-2, MELLITUS, 0302 clinical medicine, Polymorphism (computer science), Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Allele, Life Style, POLYMORPHISMS, 030304 developmental biology, Genetic association, RISK, 0303 health sciences, ENVIRONMENT, Science & Technology, COMMON VARIANTS, Genetics/Genomes/Proteomics/Metabolomics, 11 Medical And Health Sciences, medicine.disease, Endocrinology, Gene Expression Regulation, LIFE-STYLE INTERVENTION, Body mass index, Life Sciences & Biomedicine, TRAITS

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https://pure.au.dk/portal/da/publications/no-interactions-between-previously-associated-2hour-glucose-gene-variants-and-physical-activity-or-bmi-on-2hour-glucose-levelsTest(ed20e06e-7554-4130-96c3-cf15863ea109).html

المؤلفون: Fredrik Karpe, Ivonne Jarick, Julius S. Ngwa, Alan F. Wright, Robert Luben, Aaron R. Folsom, Sailaja Vedantam, Veikko Salomaa, Markku J. Savolainen, Robert Clarke, Shah Ebrahim, Thomas A. Buchanan, Mao Fu, Albert Hofman, Philippe Goyette, Camilla H. Sandholt, Fabio Macciardi, Elizabeth K. Speliotes, Barbara McKnight, Anne McCarthy, Mika Kaehoenen, Christian Gieger, Jorma S. A. Viikari, Nicholas J. Timpson, Kirsti Kvaløy, Douglas F. Levinson, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Andrew A. Hicks, Niina Pellikka, Charles C. White, Leena Peltonen, Reedik Maegi, John-Olov Jansson, Qunyuan Zhang, Claudia Lamina, Robert C. Kaplan, Peter M. Visscher, Laura J. Scott, Claes Ohlsson, Brian Thomson, Jubao Duan, Heikki V. Huikuri, Stephen O'Rahilly, Anette P. Gjesing, David P. Strachan, Caroline S. Fox, Sekar Kathiresan, Anna-Liisa Hartikainen, Johannes Kettunen, Maris Teder-Laving, Erik Ingelsson, Mario A. Morken, Peter Kovacs, Elisabeth Widen, Caroline Hayward, Eleanor Wheeler, Jing Hua Zhao, Vilmundur Gudnason, Panos Deloukas, Jacqueline C. M. Witteman, Gert-Jan B. van Ommen, Eric Boerwinkle, Martin Wabitsch, Christian Hengstenberg, Beverley Balkau, Thor Aspelund, Neelam Hassanali, Paul M. Ridker, Nicole L. Glazer, Joyce B. J. van Meurs, Michel Marre, Alan James, Ben A. Oostra, David Meyre, Ida Surakka, Stefan Schreiber, Nigel W. Rayner, Heribert Schunkert, Thomas Quertermous, Stefan Gustafsson, Peter Kraft, Benjamin F. Voight, Irene Pichler, Olle Melander, Ozren Polasek, Antti Jula, Alan R. Sanders, Andrew R. Wood, Yoav Ben-Shlomo, Thomas Illig, Jianjun Liu, Gerard Waeber, André G. Uitterlinden, Torben Hansen, Helene Alavere, André Scherag, Paolo Manunta, Johannes Hebebrand, Themistocles L. Assimes, Stefan R. Bornstein, Jaakko Tuomilehto, Morris Brown, Jianfeng Xu, Yii-Der Ida Chen, Nancy L. Heard-Costa, Cristen J. Willer, Henrik Greonberg, Guillaume Lettre, John R. Thompson, Inês Barroso, John R. B. Perry, Andreas Ziegler, James F. Wilson, Christopher J. O'Donnell, Maurizio F. Facheris, Robert Lawrence, Jan Smit, Lyle J. Palmer, Ulf Gyllensten, Richard B. Hayes, Shengxu Li, Barbara Ludwig, Larry D. Atwood, Valgerdur Steinthorsdottir, Sabine Schipf, Jouko Saramies, Tanja Boes, Martin Ridderstråle, Jennie Hui, Lina Zgaga, Susann Scherag, Alexandra I. F. Blakemore, Marjolein Peters, Timo T. Valle, Nelson B. Freimer, Kay-Tee Khaw, Amy J. Swift, Michael Stumvoll, Miriam F. Moffatt, Cecilia M. Lindgren, Ayellet V. Segrè, Neil Robertson, Richard N. Bergman, Francis S. Collins, Ryan P. Welch, Mari-Liis Tammesoo, Devin Absher, Tamara B. Harris, Kari E. North, Manuela Uda, Karen L. Mohlke, Inga Prokopenko, Per Hall, Gudmar Thorleifsson, Marjo-Riitta Järvelin, Guillaume Paré, Stefan Gaget, G. Bragi Walters, Michael N. Weedon, Jean-Claude Tardif, Mary F. Feitosa, Anke Toenjes, Ken K. Ong, Cécile Lecoeur, Paavo Zitting, David S. Siscovick, Chih-Mei Chen, Peter Almgren, Anneli Pouta, Philippe Froguel, Pekka Jousilahti, Jaakko Kaprio, Maria Teresa Sciarrone Alibrandi, Sophie van Wingerden, Steven A. McCarroll, Oluf Pedersen, Shaun Purcell, Veronique Vitart, Leena Kinnunen, Markus Perola, Jacques S. Beckmann, Vincent Vatin, Christopher J. Groves, Zoltán Kutalik, Lu Qi, Volker Hoesel, Seppo Koskinen, Suzanne Rafelt, Anke Hinney, Annette Peters, David Schlessinger, Eero Kajantie, Jian Yang, Nicholas G. Martin, Joshua W. Knowles, Kristian Midthjell, Olivier Lantieri, Dorret I. Boomsma, Harry Campbell, Ulrich John, Kirsi H. Pietilaeinen, George Davey Smith, Carl G. P. Platou, Sarah H. Wild, Patricia B. Munroe, Iris M. Heid, Diana Marek, Michael Boehnke, Andres Metspalu, Hana Lango Allen, Peter Rzehak, Christine Cavalcanti-Proença, M. Carola Zillikens, Åsa Johansson, Anuj Goel, Andrew T. Hattersley, Massimo Mangino, Michael E. Goddard, Tim D. Spector, Winfried Rief, Jonathan Tyrer, Lachlan J. M. Coin, Peter P. Pramstaller, Narisu Narisu, John Beilby, Jonathan Stephens, Christina Barlassina, Pamela Fischer-Posovszky, Brenda W.J.H. Penninx, Kaisa Silander, Richard H. Myers, Jouke-Jan Hottenga, Eric E. Schadt, Francesco P. Cappuccio, Martin den Heijer, Fernando Rivadeneira, Lindsay L. Waite, Wilmar Igl, Igor Rudan, Manjinder S. Sandhu, Debbie A Lawlor, Kristian Hveem, Susanna Wiegand, Mari Nelis, Thomas Reinehr, Elisabeth Thiering, Inke R. Koenig, Stephan B. Felix, Fredrik Wiklund, Ian N. M. Day, Willem H. Ouwehand, Peter Schwarz, Richard M. Watanabe, Keri L. Monda, Kari Stefansson, Gudny Eiriksdottir, H-Erich Wichmann, Jianxin Shi, Najaf Amin, Carlos Iribarren, Heiko Krude, Dale R. Nyholt, Lenore J. Launer, Stephen J. Chanock, Harald Grallert, Hugh Watkins, Juergen Graessler, Tsegaselassie Workalemahu, Jeanette Erdmann, Mattias Lorentzon, Leif Groop, Teresa Ferreira, Chiara Lanzani, Johanna Kuusisto, Johan G. Eriksson, Tõnu Esko, Torben Jørgensen, Robert J. Weyant, Michael Preuss, Lambertus A. Kiemeney, Daniel I. Chasman, Daniel R. Witte, Kevin B. Jacobs, Nicole Soranzo, John M. C. Connell, Soumya Raychaudhuri, Jian'an Luan, Joshua C. Randall, Joachim Heinrich, Anthony J. Balmforth, Eva Fisher, Elizabeth S. Jewell, Alice M. Arnold, Nele Friedrich, Olli T. Raitakari, Henri Wallaschofski, Jeffrey R. O'Connell, Terho Lehtimaeki, Marika Kaakinen, Heather M. Stringham, Bo Isomaa, I. Sadaf Farooqi, Anna L. Dixon, Anne U. Jackson, Mark I. McCarthy, Lori L. Bonnycastle, Aila Rissanen, Joel N. Hirschhorn, Nilesh J. Samani, Aimo Ruokonen, Frank B. Hu, L. Adrienne Cupples, Amanda J. Bennett, Shamika Ketkar, Ruth J. F. Loos, Nicholas J. Wareham, Tiinamaija Tuomi, Timothy M. Frayling, Ulla Sovio, Georg Homuth, Liming Liang, Heiner Boeing, Unnur Thorsteinsdottir, Ingrid B. Borecki, Danielle M. Greenawalt, Rosanda Mulić, Ivana Kolcic, Talin Haritunians, Mark J. Caulfield, Marja-Liisa Lokki, Tanya M. Teslovich, Paul Elliott, Matt Neville, Nilanjan Chatterjee, Albert V. Smith, Andrew P. Morris, Fabio Busonero, Gonçalo R. Abecasis, Jaana Laitinen, Michael R. Erdos, Candace Guiducci, Lee M. Kaplan, Aki S. Havulinna, Pablo V. Gejman, Alan R. Shuldiner, Serena Sanna, David J. Hunter, Sonja I. Berndt, Carla I. G. Vogel, Alistair S. Hall, Karol Estrada, Sven Bergmann, Thomas Meitinger, Gonneke Willemsen, Andrew C. Heath, Katja K.H. Aben, Markku Laakso, Juha Sinisalo, Tuomas O. Kilpelaenen, Mark E. Cooper, Heike Biebermann, Eco J. C. de Geus, Grant W. Montgomery, Sophie Visvikis-Siest, Thomas W. Winkler, Ju-Hyun Park, Alex N. Parker, Peter S. Chines, James Nemesh, Nabila Bouatia-Naji, Wendy L. McArdle, Roberto Elosua, Markku S. Nieminen

المساهمون: Psychiatry, NCA - Anxiety & Depression, EMGO - Mental health, Epidemiology, Internal Medicine, Clinical Genetics, Radiology & Nuclear Medicine, Erasmus MC other, Public Health, Biological Psychology, Neuroscience Campus Amsterdam - Anxiety & Depression, EMGO+ - Mental Health, MAGIC, Procardis Consortium, Medical Research Council (MRC), Speliotes, Ek, Willer, Cj, Berndt, Si, Monda, Kl, Thorleifsson, G, Jackson, Au, Allen, Hl, Lindgren, Cm, Luan, J, Mägi, R, Randall, Jc, Vedantam, S, Winkler, Tw, Qi, L, Workalemahu, T, Heid, Im, Steinthorsdottir, V, Stringham, Hm, Weedon, Mn, Wheeler, E, Wood, Ar, Ferreira, T, Weyant, Rj, Segrè, Av, Estrada, K, Liang, L, Nemesh, J, Park, Jh, Gustafsson, S, Kilpeläinen, To, Yang, J, BOUATIA NAJI, N, Esko, T, Feitosa, Mf, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, Av, Welch, R, Zhao, Jh, Aben, Kk, Absher, Dm, Amin, N, Dixon, Al, Fisher, E, Glazer, Nl, Goddard, Me, HEARD COSTA, Nl, Hoesel, V, Hottenga, Jj, Johansson, A, Johnson, T, Ketkar, S, Lamina, C, Li, S, Moffatt, Mf, Myers, Rh, Narisu, N, Perry, Jr, Peters, Mj, Preuss, M, Ripatti, S, Rivadeneira, F, Sandholt, C, Scott, Lj, Timpson, Nj, Tyrer, Jp, VAN WINGERDEN, S, Watanabe, Rm, White, Cc, Wiklund, F, Barlassina, C, Chasman, Di, Cooper, Mn, Jansson, Jo, Lawrence, Rw, Pellikka, N, Prokopenko, I, Shi, J, Thiering, E, Alavere, H, Alibrandi, Mt, Almgren, P, Arnold, Am, Aspelund, T, Atwood, Ld, Balkau, B, Balmforth, Aj, Bennett, Aj, BEN SHLOMO, Y, Bergman, Rn, Bergmann, S, Biebermann, H, Blakemore, Ai, Boes, T, Bonnycastle, Ll, Bornstein, Sr, Brown, Mj, Buchanan, Ta, Busonero, F, Campbell, H, Cappuccio, Fp, CAVALCANTI PROENÇA, C, Chen, Yd, Chen, Cm, Chines, P, Clarke, R, Coin, L, Connell, J, Day, In, DEN HEIJER, M, Duan, J, Ebrahim, S, Elliott, P, Elosua, R, Eiriksdottir, G, Erdos, Mr, Eriksson, Jg, Facheris, Mf, Felix, Sb, FISCHER POSOVSZKY, P, Folsom, Ar, Friedrich, N, Freimer, Nb, Fu, M, Gaget, S, Gejman, Pv, Geus, Ej, Gieger, C, Gjesing, Ap, Goel, A, Goyette, P, Grallert, H, Grässler, J, Greenawalt, Dm, Groves, Cj, Gudnason, V, Guiducci, C, Hartikainen, Al, Hassanali, N, Hall, A, Havulinna, A, Hayward, C, Heath, Ac, Hengstenberg, C, Hicks, Aa, Hinney, A, Hofman, A, Homuth, G, Hui, J, Igl, W, Iribarren, C, Isomaa, B, Jacobs, Kb, Jarick, I, Jewell, E, John, U, Jørgensen, T, Jousilahti, P, Jula, A, Kaakinen, M, Kajantie, E, Kaplan, Lm, Kathiresan, S, Kettunen, J, Kinnunen, L, Knowles, Jw, Kolcic, I, König, Ir, Koskinen, S, Kovacs, P, Kuusisto, J, Kraft, P, Kvaløy, K, Laitinen, J, Lantieri, O, Lanzani, C, Launer, Lj, Lecoeur, C, Lehtimäki, T, Lettre, G, Liu, J, Lokki, Ml, Lorentzon, M, Luben, Rn, Ludwig, B, Magic, Manunta, Paolo, Marek, D, Marre, M, Martin, Ng, Mcardle, Wl, Mccarthy, A, Mcknight, B, Meitinger, T, Melander, O, Meyre, D, Midthjell, K, Montgomery, Gw, Morken, Ma, Morris, Ap, Mulic, R, Ngwa, J, Nelis, M, Neville, Mj, Nyholt, Dr, O'Donnell, Cj, O'Rahilly, S, Ong, Kk, Oostra, B, Paré, G, Parker, An, Perola, M, Pichler, I, Pietiläinen, Kh, Platou, Cg, Polasek, O, Pouta, A, Rafelt, S, Raitakari, O, Rayner, Nw, Ridderstråle, M, Rief, W, Ruokonen, A, Robertson, Nr, Rzehak, P, Salomaa, V, Sanders, Ar, Sandhu, M, Sanna, S, Saramies, J, Savolainen, Mj, Scherag, S, Schipf, S, Schreiber, S, Schunkert, H, Silander, K, Sinisalo, J, Siscovick, D, Smit, Jh, Soranzo, N, Sovio, U, Stephens, J, Surakka, I, Swift, Aj, Tammesoo, Ml, Tardif, Jc, TEDER LAVING, M, Teslovich, Tm, Thompson, Jr, Thomson, B, Tönjes, A, Tuomi, T, VAN MEURS, Jb, VAN OMMEN, Gj, Vatin, V, Viikari, J, VISVIKIS SIEST, S, Vitart, V, Vogel, Ci, Voight, Bf, Waite, Ll, Wallaschofski, H, Walters, Gb, Widen, E, Wiegand, S, Wild, Sh, Willemsen, G, Witte, Dr, Witteman, Jc, Xu, J, Zhang, Q, Zgaga, L, Ziegler, A, Zitting, P, Beilby, Jp, Farooqi, I, Hebebrand, J, Huikuri, Hv, James, Al, Kähönen, M, Levinson, Df, Macciardi, F, Nieminen, M, Ohlsson, C, Palmer, Lj, Ridker, Pm, Stumvoll, M, Beckmann, J, Boeing, H, Boerwinkle, E, Boomsma, Di, Caulfield, Mj, Chanock, Sj, Collins, F, Cupples, La, Smith, Gd, Erdmann, J, Froguel, P, Grönberg, H, Gyllensten, U, Hall, P, Hansen, T, Harris, Tb, Hattersley, At, Hayes, Rb, Heinrich, J, Hu, Fb, Hveem, K, Illig, T, Jarvelin, Mr, Kaprio, J, Karpe, F, Khaw, Kt, Kiemeney, La, Krude, H, Laakso, M, Lawlor, Da, Metspalu, A, Munroe, Pb, Ouwehand, Wh, Pedersen, O, Penninx, Bw, Peters, A, Pramstaller, Pp, Quertermous, T, Reinehr, T, Rissanen, A, Rudan, I, Samani, Nj, Schwarz, Pe, Shuldiner, Ar, Spector, Td, Tuomilehto, J, Uda, M, Uitterlinden, A, Valle, Tt, Wabitsch, M, Waeber, G, Wareham, Nj, Watkins, H, Procardis, Consortium, Wilson, Jf, Wright, Af, Zillikens, Mc, Chatterjee, N, Mccarroll, Sa, Purcell, S, Schadt, Ee, Visscher, Pm, Assimes, Tl, Borecki, Ib, Deloukas, P, Fox, C, Groop, Lc, Haritunians, T, Hunter, Dj, Kaplan, Rc, Mohlke, Kl, O'Connell, Jr, Peltonen, L, Schlessinger, D, Strachan, Dp, VAN DUIJN, Cm, Wichmann, He, Frayling, Tm, Thorsteinsdottir, U, Abecasis, Gr, Barroso, I, Boehnke, M, Stefansson, K, North, Ke, Mccarthy, Mi, Hirschhorn, Jn, Ingelsson, E, Loos, Rj

المصدر: Nature Genetics, 42(11), 937
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Hottenga, J J, de Geus, E J C, Martin, N G, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Zillikens, M C, Visscher, P M, Peltonen, L, van Duijn, C M, Thorsteinsdottir, U, Abecasis, G R, Barroso, I, Boehnke, M, Stefansson, K, North, K E, McCarthy, M I, Hirschhorn, J N, Ingelsson, E & Loos, R J F 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-948 . https://doi.org/10.1038/ng.686Test
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Aben, K K, Absher, D M, Amin, N, Dixon, A L, Fisher, E, Glazer, N L, Goddard, M E, Witte, D, Pedersen, O & MAGIC 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686Test
Nature genetics
Nature Genetics, 42(11), 937-948. Nature Publishing Group
Nature Genetics; Vol 42
Nature Genetics, 42(11), 937-U53. Nature Publishing Group
Nature Genetics
Nature Genetics, 42, 937-48
Nature genetics, vol. 42, no. 11, pp. 937-948
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Allen, H L, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Campbell, H, Hayward, C, Vitart, V, Wild, S H, Zgaga, L, Rudan, I, Wilson, J F & Wright, A F & Visscher, P M 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686Test
Nature Genetics, 42, 11, pp. 937-48

مصطلحات موضوعية: Netherlands Twin Register (NTR), Medizin, Genome-wide association study, Aetiology, screening and detection [ONCOL 5], FTO gene, Body Mass Index, 0302 clinical medicine, SH2B1, GASTRIC-INHIBITORY POLYPEPTIDE, ADULT OBESITY, Glucose homeostasis, Body Size, GENETICS & HEREDITY, 2. Zero hunger, Genetics, Genetics & Heredity, RISK, 0303 health sciences, Neuronal growth regulator 1, Genetics of obesity, COMMON VARIANTS, Chromosome Mapping, 11 Medical And Health Sciences, Body Height/genetics, Body Size/genetics, Body Weight/genetics, European Continental Ancestry Group/genetics, Genetic Predisposition to Disease/genetics, Genome-Wide Association Study, Humans, Obesity/genetics, Polymorphism, Single Nucleotide, FAT MASS, Body Height/*genetics *Body Mass Index Body Size/genetics Body Weight/*genetics *Chromosome Mapping European Continental Ancestry Group/genetics Genetic Predisposition to Disease/genetics Genome-Wide Association Study Humans Obesity/genetics Polymorphism, Single Nucleotide, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, MELANOCORTIN-4 RECEPTOR GENE, Life Sciences & Biomedicine, European Continental Ancestry Group, EARLY-ONSET, 030209 endocrinology & metabolism, Locus (genetics), Biology, Article, White People, Molecular epidemiology [NCEBP 1], 03 medical and health sciences, SDG 3 - Good Health and Well-being, body mass index, genome-wide association, meta-analysis, Genetic Predisposition to Disease, Obesity, GENOME-WIDE ASSOCIATION, FTO GENE, 030304 developmental biology, Science & Technology, genome-wide association gastric-inhibitory polypeptide melanocortin-4 receptor gene glucose-homeostasis common variants adult obesity early-onset fat mass risk metaanalysis, Body Weight, 06 Biological Sciences, MAGIC, Body Height, GLUCOSE-HOMEOSTASIS, Procardis Consortium, Body mass index, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7dd940bce9e9209645e6816dc4e081Test
http://hdl.handle.net/1887/116783Test

المؤلفون: François Pattou, Thomas Sparsø, Eleftheria Zeggini, Michael N. Weedon, J. Graessler, Mandy van Hoek, Suzette J. Bielinski, Amy J. Swift, David S. Siscovick, Michael R. Erdos, Kenneth Rice, Nabila Bouatia-Naji, Benjamin F. Voight, Wolfgang Rathmann, Jarred B. McAteer, Caroline S. Fox, Kari Stefansson, Vincent Mooser, Philippe Froguel, Gordon H. Williams, Mike Sampson, Annelli Sandbæk, Jeffrey R. O'Connell, Stefan R. Bornstein, Robert Sladek, Andrew D. Morris, Torben Jørgensen, Suzannah Bumpstead, Ruth E. Pakyz, James B. Meigs, Denis Rybin, Peter Vollenweider, Valle Tt, Andrew T. Hattersley, Amélie Bonnefond, Knut Krohn, Kijoung Song, Erik Ingelsson, Mario A. Morken, Laura J. Scott, Richard M. Watanabe, Eric J.G. Sijbrands, David Altshuler, Harald Grallert, Vladimir Mayor, Yii-Der Ida Chen, Heather M. Stringham, Bruce M. Psaty, Andrew B. Singleton, Nicole L. Glazer, Peter Schwarz, Jaakko Tuomilehto, Mathieu Firmann, Yvonne Böttcher, Knut Borch-Johnsen, Josée Dupuis, Unnur Thorsteinsdottir, Thomas A. Buchanan, Avan Aihie Sayer, Inga Prokopenko, Thomas Illig, Inês Barroso, Aroon D. Hingorani, Daniel S. Pearson, Luigi Ferrucci, Anna Köttgen, H.-Erich Wichmann, Peter Shrader, Yurii S. Aulchenko, Lu Qi, Olivier Le Bacquer, Eric J. Brunner, Meena Kumari, Karen L. Mohlke, Valgerdur Steinthorsdottir, Laura Pascoe, Lori L. Bonnycastle, Francis S. Collins, Jérôme Delplanque, Guillaume Charpentier, Michael Stumvoll, Mark O. Goodarzi, Felicity Payne, Ruth J. F. Loos, Richard N. Bergman, Gudmar Thorleifsson, Beverley Balkau, Jing Hua Zhao, Timothy M. Frayling, Josephine M. Egan, Kristin Ardlie, Stephen J. Sharp, Jalal Taneera, Mark Walker, W. H. Linda Kao, Nicholas L. Smith, Niels Grarup, Nita G. Forouhi, Oluf Pedersen, Cécile Lecoeur, Andrew Walley, Ann-Christine Syvänen, Eric Boerwinkle, Toby Johnson, Camilla H. Andreasen, Jian Anluan, Dawn M. Waterworth, Toshiko Tanaka, Braxton D. Mitchell, Alisa K. Manning, James S. Pankow, Valeriya Lyssenko, Mika Kivimäki, David Couper, Alex S. F. Doney, Nicholas J. Wareham, Tiinamaija Tuomi, Johanna Kuusisto, Torben Hansen, Christine Cavalcanti-Proença, Richa Saxena, Markku Laakso, James F. Wilson, Bo Isomaa, Marilyn C. Cornelis, David Meyre, Anne U. Jackson, Holly E. Syddall, Alan R. Shuldiner, Michael Boehnke, Peter M. Nilsson, Gabriel Crawford, Claudia Langenberg, Jerome I. Rotter, Peter S. Chines, Cyrus Cooper, Peter Kovacs, Torsten Lauritzen, Christian Dina, Gerard Waeber, Man Li, Anke Tönjes, Narisu Narisu, Jose C. Florez, David M. Nathan, Leif Groop, Claire Levy-Marchal, Cornelia M. van Duijn, Mark I. McCarthy, Frank B. Hu, Trine Welløv Boesgaard, Colin N. Apalmer, Michael Marmot

المساهمون: GIANT consortium, MAGIC investigators, Ophthalmology, Internal Medicine, Epidemiology

المصدر: Saxena, R, Hivert, M-F, Langenberg, C, Tanaka, T, Pankow, J S, Vollenweider, P, Lyssenko, V, Bouatia-Naji, N, Dupuis, J, Jackson, A U, Kao, W H L, Li, M, Glazer, N L, Manning, A K, Luan, J, Stringham, H M, Prokopenko, I, Johnson, T, Grarup, N, Boesgaard, T W, Lecoeur, C, Shrader, P, O'Connell, J, Ingelsson, E, Couper, D J, Rice, K, Song, K, Andreasen, C H, Dina, C, Köttgen, A, Le Bacquer, O, Pattou, F, Taneera, J, Steinthorsdottir, V, Rybin, D, Ardlie, K, Sampson, M, Qi, L, van Hoek, M, Weedon, M N, Aulchenko, Y S, Voight, B F, Grallert, H, Balkau, B, Bergman, R N, Bielinski, S J, Bonnefond, A, Bonnycastle, L L, Lauritzen, T, Sandbaek, A & GIANT Consortium 2010, ' Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge ', Nature Genetics, vol. 42, no. 2, pp. 142-8 . https://doi.org/10.1038/ng.521Test
Nature genetics
Saxena, R, Hivert, M-F, Langenberg, C, Tanaka, T, Pankow, J S, Vollenweider, P, Lyssenko, V, Bouatia-Naji, N, Dupuis, J, Jackson, A U, Kao, W H L, Li, M, Glazer, N L, Manning, A K, Luan, J, Stringham, H M, Prokopenko, I, Johnson, T, Grarup, N, Boesgaard, T W, Lecoeur, C, Shrader, P, O'Connell, J, Ingelsson, E, Couper, D J, Rice, K, Song, K, Andreasen, C H, Dina, C, Koettgen, A, Le Bacquer, O, Pattou, F, Taneera, J, Steinthorsdottir, V, Rybin, D, Ardlie, K, Sampson, M, Qi, L, van Hoek, M, Weedon, M N, Aulchenko, Y S, Voight, B F, Grallert, H, Balkau, B, Bergman, R N, Bielinski, S J, Bonnefond, A, Bonnycastle, L L & Wilson, J F & Morris, A 2010, ' Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge ', Nature Genetics, vol. 42, no. 2, pp. 142-U75 . https://doi.org/10.1038/ng.521Test
Saxena, R, Hivert, M-F, Langenberg, C, Tanaka, T, Pankow, J S, Vollenweider, P, Lyssenko, V, Bouatia-Naji, N, Dupuis, J, Jackson, A U, Kao, W H L, Li, M, Glazer, N L, Manning, A K, Luan, J, Stringham, H M, Prokopenko, I, Johnson, T, Grarup, N, Boesgaard, T W, Lecoeur, C, Shrader, P, O'Connell, J, Ingelsson, E, Couper, D J, Rice, K, Song, K, Andreasen, C H, Dina, C, Köttgen, A, Le Bacquer, O, Pattou, F, Taneera, J, Steinthorsdottir, V, Rybin, D, Ardlie, K, Sampson, M, Qi, L, van Hoek, M, Weedon, M N, Aulchenko, Y S, Voight, B F, Grallert, H, Balkau, B, Bergman, R N, Bielinski, S J, Bonnefond, A, Bonnycastle, L L, Borch-Johnsen, K, Böttcher, Y, Brunner, E, Buchanan, T A, Bumpstead, S J, Cavalcanti-Proença, C, Charpentier, G, Chen, Y-D I, Chines, P S, Collins, F S, Cornelis, M, J Crawford, G, Delplanque, J, Doney, A, Egan, J M, Erdos, M R, Firmann, M, Forouhi, N G, Fox, C S, Goodarzi, M O, Graessler, J, Hingorani, A, Isomaa, B, Jørgensen, T, Kivimaki, M, Kovacs, P, Krohn, K, Kumari, M, Lauritzen, T, Lévy-Marchal, C, Mayor, V, McAteer, J B, Meyre, D, Mitchell, B D, Mohlke, K L, Morken, M A, Narisu, N, Palmer, C N A, Pakyz, R, Pascoe, L, Payne, F, Pearson, D, Rathmann, W, Sandbaek, A, Sayer, A A, Scott, L J, Sharp, S J, Sijbrands, E, Singleton, A, Siscovick, D S, Smith, N L, Sparsø, T, Swift, A J, Syddall, H, Thorleifsson, G, Tönjes, A, Tuomi, T, Tuomilehto, J, Valle, T T, Waeber, G, Walley, A, Waterworth, D M, Zeggini, E, Zhao, J H, Illig, T, Wichmann, H E, Wilson, J F, van Duijn, C, Hu, F B, Morris, A D, Frayling, T M, Hattersley, A T, Thorsteinsdottir, U, Stefansson, K, Nilsson, P, Syvänen, A-C, Shuldiner, A R, Walker, M, Bornstein, S R, Schwarz, P, Williams, G H, Nathan, D M, Kuusisto, J, Laakso, M, Cooper, C, Marmot, M, Ferrucci, L, Mooser, V, Stumvoll, M, Loos, R J F, Altshuler, D, Psaty, B M, Rotter, J I, Boerwinkle, E, Hansen, T, Pedersen, O, Florez, J C, McCarthy, M I, Boehnke, M, Barroso, I, Sladek, R, Froguel, P, Meigs, J B, Groop, L, Wareham, N J & Watanabe, R M 2010, ' Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge ', Nature Genetics, vol. 42, no. 2, pp. 142-8 . https://doi.org/10.1038/ng.521Test
Nature Genetics, vol. 42, no. 2, pp. 142-148
Nature Genetics; Vol 42
Nature Genetics
Nature Genetics, 42(2), 142-U75. Nature Publishing Group

مصطلحات موضوعية: Adenylate Cyclase, Male, medicine.medical_specialty, medicine.medical_treatment, Denmark, Incretin, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Carbohydrate metabolism, Incretins, Polymorphism, Single Nucleotide, Article, Body Mass Index, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Meta-Analysis as Topic, Internal medicine, Diabetes mellitus, medicine, Genetics, Humans, Insulin, RNA, Messenger, 030304 developmental biology, 0303 health sciences, Glucose tolerance test, medicine.diagnostic_test, Gene Expression Profiling, Genetic Variation, Proteins, Glucose Tolerance Test, medicine.disease, Adenylate Cyclase/genetics, Denmark%22">Type="Geographic">Denmark, Diabetes Mellitus, Type 2/genetics, Female, Gene Expression Regulation, Genetic Loci/genetics, Genome-Wide Association Study, Glucose/metabolism, Incretins/genetics, Insulin/metabolism, Polymorphism, Single Nucleotide/genetics, Proteins/genetics, RNA, Messenger/genetics, RNA, Messenger/metabolism, Receptors, Gastrointestinal Hormone/genetics, Receptors, Gastrointestinal Hormone/metabolism, Colaus Study, Glucagon-like peptide-1, Endocrinology, Glucose, Diabetes Mellitus, Type 2, Genetic Loci, TCF7L2, Adenylyl Cyclases

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https://pure.au.dk/portal/da/publications/genetic-variation-in-gipr-influences-the-glucose-and-insulin-responses-to-an-oral-glucose-challengeTest(0b6bb44f-2d27-4aef-8313-cfafcdc8f39d).html

المؤلفون: Karol Estrada, Thomas Meitinger, Christopher J. Groves, Tim D. Spector, Paul W. Franks, Weihua Zhang, Nicholas J. Timpson, Leena Peltonen, M. Carola Zillikens, Alexander W. Drong, Leonie C. Jacobs, Massimo Mangino, Nita G. Forouhi, Fredrik Karpe, Inga Prokopenko, Amanda J. Bennett, G. Mark Lathrop, Cornelia M. van Duijn, Albert Hofman, Michael Boehnke, Inês Barroso, Veikko Salomaa, Lu Qi, John F. Peden, Fernando Rivadeneira, Mark I. McCarthy, Jaakko Tuomilehto, Joel N. Hirschhorn, Nilesh J. Samani, Frank B. Hu, Edward G. Lakatta, Alex S. F. Doney, Najaf Amin, Anders Hamsten, Hugh Watkins, Johanna Kuusisto, Elizabeth K. Speliotes, Narisu Narisu, Guido Fischer, Wendy L. McArdle, David Hadley, Manjinder S. Sandhu, Francis S. Collins, Paul Elliott, Vincent Mooser, Luigi Ferrucci, Leif Groop, H.-Erich Wichmann, Serena Sanna, Xin Yuan, Anna F. Dominiczak, Peter S. Chines, Lachlan J. M. Coin, Lynn Cherkas, Cyrus Cooper, Mario A. Morken, Colin N. A. Palmer, Frida Renström, Blanca M. Herrera, Kijoung Song, Markku Laakso, Marjo-Riitta Järvelin, Kaisa Silander, David Schlessinger, Kari Stefansson, Peter Nordström, David P. Strachan, Angelo Scuteri, Michael N. Weedon, Jia N.an Luan, Rolf Holle, Joshua C. Randall, Yurii S. Aulchenko, Aimo Ruokonen, Stefania Bandinelli, Andrew D. Morris, Shah Ebrahim, Noha Lim, Nicholas J. Wareham, Tiinamaija Tuomi, Mark J. Caulfield, Paul Scheet, Karen L. Mohlke, Gudmar Thorleifsson, Debbie A Lawlor, Karen A. Jameson, Peter Almgren, Lori L. Bonnycastle, Candace Guiducci, Timothy M. Frayling, David J. Hunter, Amy J. Swift, Peter Vollenweider, Iris M. Heid, Stephen J. Chanock, Felicity Payne, Ruth J. F. Loos, George Davey Smith, Gonçalo R. Abecasis, Jaana Laitinen, Andrew T. Hattersley, Cristen J. Willer, Suzannah Bumpstead, G. Bragi Walters, Pekka Jousilahti, Harald Grallert, Laura J. Scott, Panos Deloukas, Cuilin Zhang, Ben A. Oostra, Thomas Illig, Claudia Lamina, Dawn M. Waterworth, Angela Doering, Patricia B. Munroe, Toshiko Tanaka, Chris Wallace, Unnur Thorsteinsdottir, Gabriel Crawford, John C. Chambers, John W. Holloway, Christian Gieger, Gérard Waeber, Jacqueline C.M. Witteman, Ian N. M. Day, Michael R. Erdos, Augustine Kong, Bo Isomaa, Anne U. Jackson, Scott M. Grundy, Andrew P. Morris, Hua Zhao Jing, Aki S. Havulinna, André G. Uitterlinden, Valgerdur Steinthorsdottir, Cecilia M. Lindgren, Richard N. Bergman, Anna Nordström, Manuela Uda, Jaspal S. Kooner, Nicole Soranzo, Heather M. Stringham, Helen N. Lyon

المساهمون: Broad Institute of MIT and Harvard, Peltonen, Leena, Hunter, David J., Guiducci, Candace, Crawford, Gabriel, Hirschhorn, Joel N., Lyon, Helen N., Speliotes, Elizabeth K., Medical Research Council (MRC)

المصدر: PLoS genetics
PLoS Genet. 5:e1000508 (2009)
PLoS Genetics, vol. 5, no. 6, pp. e1000508
PLoS
PLoS Genetics
PLoS Genetics; Vol 5
Lindgren, C M, Heid, I M, Randall, J C, Lamina, C, Steinthorsdottir, V, Qi, L, Speliotes, E K, Thorleifsson, G, Willer, C J, Herrera, B M, Jackson, A U, Lim, N, Scheet, P, Soranzo, N, Amin, N, Aulchenko, Y S, Chambers, J C, Drong, A, Luan, J, Lyon, H N, Rivadeneira, F, Sanna, S, Timpson, N J, Zillikens, M C, Jing, H Z, Almgren, P, Bandinelli, S, Bennett, A J, Bergman, R N, Bonnycastle, L L, Bumpstead, S J, Chanock, S J, Cherkas, L, Chines, P, Coin, L, Cooper, C, Crawford, G, Doering, A, Dominiczak, A, Doney, A S F, Ebrahim, S, Elliott, P, Erdos, M R, Estrada, K, Ferrucci, L, Fischer, G, Forouhi, N G, Gieger, C, Grallert, H, Groves, C J, Grundy, S, Guiducci, C, Hadley, D, Hamsten, A, Havulinna, A S, Hofman, A, Holle, R, Holloway, J W, Illig, T, Isomaa, B, Jacobs, L C, Jameson, K, Jousilahti, P, Karpe, F, Kuusisto, J, Laitinen, J, Lathrop, G M, Lawlor, D A, Mangino, M, McArdle, W L, Meitinger, T, Morken, M A, Morris, A P, Munroe, P, Narisu, N, Nordström, A, Nordström, P, Oostra, B A, Palmer, C N A, Payne, F, Peden, J F, Prokopenko, I, Renström, F, Ruokonen, A, Salomaa, V, Sandhu, M S, Scott, L J, Scuteri, A, Silander, K, Song, K, Yuan, X, Stringham, H M, Swift, A J, Tuomi, T, Uda, M, Vollenweider, P, Waeber, G, Wallace, C, Walters, G B, Weedon, M N, Witteman, J C M, Zhang, C, Zhang, W, Caulfield, M J, Collins, F S, Smith, G D, Day, I N M, Franks, P W, Hattersley, A T, Hu, F B, Jarvelin, M R, Kong, A, Kooner, J S, Laakso, M, Lakatta, E, Mooser, V, Morris, A D, Peltonen, L, Samani, N J, Spector, T D, Strachan, D P, Tanaka, T, Tuomilehto, J, Uitterlinden, A G, Van Duijn, C M, Wareham, N J, Watkins, H, Waterworth, D M, Boehnke, M, Deloukas, P, Groop, L, Hunter, D J, Thorsteinsdottir, U, Schlessinger, D, Wichmann, H E, Frayling, T M, Abecasis, G R, Hirschhorn, J N, Loos, R J F, Stefansson, K, Mohlke, K L, Barroso, I & McCarthy, M I 2009, ' Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution ', PLoS Genetics, vol. 5, no. 6, e1000508 . https://doi.org/10.1371/journal.pgen.1000508Test
PLoS Genetics, Vol 5, Iss 6, p e1000508 (2009)

مصطلحات موضوعية: Male, Cancer Research, Genome-wide association study, Giant Consortium, QH426-470, FTO gene, Body Mass Index, Cohort Studies, Diabetes and Endocrinology/Obesity, 0302 clinical medicine, Waist–hip ratio, Germany, Body Fat Distribution, Environmental conditions, Age of Onset, Procardis Consortia, Child, Genetics and Genomics/Genetics of Disease, Genetics (clinical), Adiposity, Genetics & Heredity, Genetics and Genomics/Medical Genetics, Genetics, 0303 health sciences, 3. Good health, Diabetes and Endocrinology, Wellcome Trust Case Control Consortium, Female, France, Waist Circumference, Lysophospholipase, Oxidoreductases, Life Sciences & Biomedicine, Research Article, Adult, Waist, Adolescent, Single-nucleotide polymorphism, Genetics and Genomics/Complex Traits, Biology, Polymorphism, Single Nucleotide, Sequence variants, 03 medical and health sciences, SDG 3 - Good Health and Well-being, medicine, Humans, Genetic Predisposition to Disease, Obesity, Diabetes and Endocrinology/Type 2 Diabetes, Molecular Biology, Alleles, Ecology, Evolution, Behavior and Systematics, Imputation, 030304 developmental biology, Genetic association, waist circumference, adult obesity, fto gene, environmental-conditions, insulin-resistance, sequence variants, common variants, expression, imputation, height, 0604 Genetics, Science & Technology, Height, Genome, Human, Waist-Hip Ratio, Common variants, Body Weight, Genetics and Genomics, Insulin-resistance, medicine.disease, Transcription Factor AP-2, Genetic Loci, Methionine Sulfoxide Reductases, Adult obesity, Body mass index, 030217 neurology & neurosurgery, Developmental Biology, Genome-Wide Association Study

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https://openaccess.sgul.ac.uk/id/eprint/1561/1/pgen.1000508.pdfTest