دورية أكاديمية
Insight on Bluetongue virus transmission in small ruminants in Senegal
| العنوان: | Insight on Bluetongue virus transmission in small ruminants in Senegal |
|---|---|
| المؤلفون: | Gahn, Marie Cicille Ba, Seck, Momar Talla, Ciss, Mamadou, Lo, Modou Moustapha, Ndiaye, Mbengué, Fall, Moussa, Biteye, Biram, Sailleau, Corinne, Viarouge, Cyril, Postic, Lydie, Zientara, Stéphan, Bréard, Emmanuel, Fall, Assane Gueye |
| المساهمون: | Laboratoire National d'Elevage et de Recherches Vétérinaires Dakar (LNERV), Institut Sénégalais de Recherches Agricoles Dakar (ISRA), Virologie UMR1161 (VIRO), École nationale vétérinaire d'Alfort (ENVA)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), European Project: 727393,H2020,H2020-EU.3.2.1.1.,PALE-Blu(2017) |
| المصدر: | ISSN: 0001-706X. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Senegal, Seroprevalence, Bluetongue, Risk factors, MESH: Bluetongue virus, MESH: Bluetongue, MESH: Goat Diseases, MESH: Senegal, MESH: Sheep, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Bluetongue (BT) is an infectious, arthropod-borne viral disease of domestic and wild ruminants. The disease causes animal mortality, production decrease and commercial limits for herds. Despite the active circulation of the disease in the world, few studies have been carried out in Senegal. The objective of this study was to assess the current prevalence of BT in small ruminants and the serotypes circulating in Senegal. A cross-sectional study was conducted in the fourteen regions of Senegal. After the sampling campaign, sera collected in sheep and goats herds were screened for the presence of Bluetongue virus (BTV) specific antibodies using c-Elisa. The whole blood of seropositive animals was further analyzed by RT-qPCR and positive samples were typed to identify BTV serotypes. Analysis of several risk factors such as age, sex and species of animals was performed using logistic regression. The overall seroprevalence of BTV in Senegal was 72.6% (95% CI: 70.3-74.9%) with 75.9% (95% CI: 72.2-79.5%) in goat and 70.6% (95% CI: 67.5-73.6%) in sheep. Female (prevalence=77.1%) and adult (prevalence=80%) animals showed the highest seropositivity to BTV compared respectively to male (55.7%, p=6.133e-09) and young (49.4%, p < 2.2e-16). The RT-qPCR results showed the presence of BT viral genome in 359 small ruminants. The results obtained from serological and genotyping studies showed an active spread of the Bluetongue virus in domestic ruminants and phylogenetic analysis showed that the BTV-2 is one of the circulating serotypes in Senegal. This study allows having baseline information for controlling Bluetongue in Senegal. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35487295; info:eu-repo/grantAgreement//727393/EU/Understanding pathogen, livestock, environment interactions involving bluetongue virus/PALE-Blu; anses-03897924; https://anses.hal.science/anses-03897924Test; PUBMED: 35487295; WOS: 000798549100008 |
| DOI: | 10.1016/j.actatropica.2022.106487 |
| الإتاحة: | https://doi.org/10.1016/j.actatropica.2022.106487Test https://anses.hal.science/anses-03897924Test |
| حقوق: | http://hal.archives-ouvertes.fr/licences/copyrightTest/ |
| رقم الانضمام: | edsbas.EBC2A2A2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.actatropica.2022.106487 |
|---|