التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of the post-transfusion platelet increment and safety of riboflavin-based pathogen reduction technology (PRT) treated platelet products stored in platelet additive solution for 5 days or less versus 6–7 days. |
| المؤلفون: |
Kaplan, Alesia1, Lindgren, Bruce2, Marschner, Susanne3, Aznar, Marivi4, Zalba, Saioa4, Sánchez, Piva4, Ayape, María Luisa5, Olavarría, Eduardo4, Antelo, Maria Luisa4 manteloc@cfnavarra.es |
| المصدر: |
Transfusion & Apheresis Science. Apr2016, Vol. 54 Issue 2, p248-252. 5p. |
| مصطلحات موضوعية: |
*BLOOD platelet transfusion, *VITAMIN B2, *MEDICATION safety, *PLATELET count, *HEMATOLOGY, *ADVERSE health care events, *VITAMIN therapy |
| مستخلص: |
Background and Objectives Platelets are stored routinely for 5 days or less and extended platelet storage time could improve product availability. This study compared platelet count increments (CI 24hs ) of riboflavin plus UV-light (PRT) treated platelet products in platelet additive solution stored for 5 days or less to products stored for 6–7 days. Material and Methods This was a retrospective study comparing CI 24hs between two groups. Hematology patients received PRT treated platelet products stored for <5 days, or for 6–7 days. Platelet counts and adverse events during and up to 24 hours after transfusion were recorded and compared between the groups. Results Ninety-seven patients received 168 transfusions of <5 day old PRT-treated platelets and 49 patients received 74 transfusions of 6–7 day old PRT-treated platelets. There was no statistically significant difference in CI 24hs between the <5 day (median 6000) and 6–7 day storage group (median 8000) (p-value = 0.509). One mild fever was documented in the <5 day storage group. Conclusion CI 24hs are similar for PRT-treated PLTs stored in PAS for <5 or 6–7 days. Studies to further evaluate clinical outcomes such as bleeding are ongoing. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
