التفاصيل البيبلوغرافية
| العنوان: |
Severe Hypothermia Increases the Risk for Intensive Care Unit-Acquired Infection. |
| المؤلفون: |
Laupland, Kevin B., Zahar, Jean-Ralph, Adrie, Christophe, Minet, Clé:mence, Vé sin, Auré lien, Goldgran-Toledano, Dany, Azoulay, Elie, Garrouste-Orgeas, Maité, Cohen, Yves, Schwebel, Carole, Jamali, Samir, Darmon, Michael, Dumenil, Anne-Sylvie, Kallel, Hatem, Souweine, Bertrand, Timsit, Jean-Francxois |
| المصدر: |
Clinical Infectious Diseases; 4/15/2012, Vol. 54 Issue 8, p1064-1070, 7p |
| مصطلحات موضوعية: |
HYPOTHERMIA, INTENSIVE care units, NOSOCOMIAL infections, PNEUMONIA, BLOOD diseases, HOSPITAL admission & discharge, MEDICAL statistics |
| مستخلص: |
Although hypothermia is widely accepted as a risk factor for subsequent infection in surgical patients, it has not been well defined in medical patients. We sought to assess the risk of acquiring intensive care unit (ICU)-acquired infection after hypothermia among medical ICU patients. Methods. Adults (≤18 years) admitted to French ICUs for at least 2 days between April 2000 and November 2010 were included. Surgical patients were excluded. Patient were classified as having had mild hypothermia (35.0°C-35.9°C), moderate hypothermia (32°C-34.9°C), or severe hypothermia (<32°C), and were followed for the development of pneumonia or bloodstream infection until ICU discharge Results. A total of 6237 patients were included. Within the first day of admission, 648 (10%) patients had mild hypothermia, 288 (5%) patients had moderate hypothermia, and 45 (1%) patients had severe hypothermia. Among the 5256 patients who did not have any hypothermia at day 1, subsequent hypothermia developed in 868 (17%), of which 673 (13%), 176 (3%), and 19 (<1%) patients had lowest temperatures of 35.0°C-35.9°C, 32.0°C-34.9°C, and <32°C, respectively. During the course of ICU admission, 320 (5%) patients developed ICU-acquired bloodstream infection and 724 (12%) patients developed ICU-acquired pneumonia. After controlling for confounding variables in multivariable analyses, severe hypothermia was found to increase the risk for subsequent ICU-acquired infection, particularly in patients who did not present with severe sepsis or septic shock. Conclusions. The presence of severe hypothermia is a risk factor for development of ICU-acquired infection in medical patients. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
