التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of 311 contemporary cases of stereotactic biopsies in patients with neoplastic and non-neoplastic lesions—diagnostic yield and management of non-diagnostic cases. |
| المؤلفون: |
Pasternak, Krystyna Agnieszka, Schwake, Michael, Warneke, Nils, Masthoff, Max, Zawy Alsofy, Samer, Suero Molina, Eric, Stummer, Walter, Schipmann, Stephanie |
| المصدر: |
Neurosurgical Review; Oct2021, Vol. 44 Issue 5, p2597-2609, 13p |
| مصطلحات موضوعية: |
REVENUE management, BRAIN damage, BIOPSY, BRAIN tumors, ADULTS, DIAGNOSIS |
| مستخلص: |
Stereotactic biopsies are an established tool for obtaining diagnosis of unclear brain lesions. However, non-diagnostic biopsies still occur. We aimed to analyze the contemporary diagnostic yield of stereotactic biopsies, predictors for non-diagnostic biopsies, outcome, and follow-up strategy after non-diagnostic biopsy. We conducted a single-center retrospective study of 311 adult patients undergoing stereotactic biopsies due to a newly diagnosed lesion at our department between 2012 and 2018. Patient data regarding comorbidities, presenting symptoms, imaging features, and non-invasive diagnostic procedures were obtained. The overall diagnostic yield was 86.2% and differed significantly between the various suspected diagnosis groups and was the highest when suspecting primary brain tumor compared with non-neoplastic lesions (91.2% vs. 73.3%, p > 0.001). Predicators for non-diagnostic biopsies were small lesion size, lack of contrast-enhancement, presence of sepsis, or underlying hemato-oncological disease. In case of non-diagnostic biopsy, a re-biopsy was performed in 12 cases, revealing a final diagnosis in 75%. In 16 cases, empiric therapy was started based on the suspected underlying disease. Close follow-up was performed in the remaining 15 cases. We showed that stereotactic biopsy is a safe procedure with reasonable diagnostic yield even for non-neoplastic lesions, when non-invasive diagnostic was inconclusive. In addition, we developed treatment recommendations for cases of non-diagnostic biopsies. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
