المؤلفون: Shi Chen, Lai Peng, Yifeng Xu, Ning Wang, Xi Wang, Chuanzhou Liang, Kang Song, Yan Zhou

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, batch experimental data, based operational strategy, sidestream partial nitritation, based sidestream processes, model simulation showed, sidestream pharmaceutical removal, regulate fna levels, atenolol biodegradation efficiencies, type inhibition kinetics, pn process could, atenolol removal efficiency, nitritation efficiency, atenolol biodegradation, processes characterized, fna inhibition, anammox process, atenolol removal, model prediction, model framework, induced biodegradation, simultaneous removal, ∼ 99, ∼ 60

العلاقة: https://figshare.com/articles/journal_contribution/Modeling_Free_Nitrous_Acid_Inhibition_on_the_Removal_of_Nitrogen_and_Atenolol_during_Sidestream_Partial_Nitritation_Processes/25226845Test

الإتاحة: https://doi.org/10.1021/acs.est.3c10107.s001Test
https://figshare.com/articles/journal_contribution/Modeling_Free_Nitrous_Acid_Inhibition_on_the_Removal_of_Nitrogen_and_Atenolol_during_Sidestream_Partial_Nitritation_Processes/25226845Test

المؤلفون: Jayalakshmi Jayan, Jiseong Lee, Sunil Kumar, Amritha Manoharan, Anishma Payyappilliparambil Narayanan, Reenoo Jauhari, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Hasnaa Ali Ebrahim, Subin Mary Zachariah, Hoon Kim, Bijo Mathew

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Developmental Biology, Chemical Sciences not elsewhere classified, strongest inhibitory activity, showed effective recoveries, reversibility experiment using, maximum inhibitory concentration, block monoamine oxidase, b inhibitory activities, ach3 , ach14 , ach10 , inhibition kinetics study, <, 50 , 10 ± 0, 097 ± 0, hit compound ach10, reversible competitive mao, b inhibition, reversible reference, competitive inhibitors, b resulted, b inhibitors, inhibition effect, – f, series concluded

العلاقة: https://figshare.com/articles/journal_contribution/Development_of_a_New_Class_of_Monoamine_Oxidase_B_Inhibitors_by_Fine-Tuning_the_Halogens_on_the_Acylhydrazones/24751895Test

الإتاحة: https://doi.org/10.1021/acsomega.3c05719.s001Test
https://figshare.com/articles/journal_contribution/Development_of_a_New_Class_of_Monoamine_Oxidase_B_Inhibitors_by_Fine-Tuning_the_Halogens_on_the_Acylhydrazones/24751895Test

المؤلفون: Cristiano Mota (8554977), Ana Diniz (5354180), Catarina Coelho (498028), Teresa Santos-Silva (503787), Mariam Esmaeeli (11307012), Silke Leimkühler (1327842), Eurico J. Cabrita (518149), Filipa Marcelo (1507666), Maria João Romão (3114780)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, Human Aldehyde Oxidase, enzyme inhibition kinetics, substrate, raloxifene, inhibitor, hAOX 1, benzamidine, Raloxifene Case Human aldehyde oxidase, NMR

العلاقة: https://figshare.com/articles/journal_contribution/Interrogating_the_Inhibition_Mechanisms_of_Human_Aldehyde_Oxidase_by_X_ray_Crystallography_and_NMR_Spectroscopy_The_Raloxifene_Case/15831744Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c01125.s001Test

المؤلفون: Sridhar S. N. C (10871035), Pracheta Sengupta (10871038), Saksham Palawat (10871041), Dileep P. S. (10871044), Ginson George (9290954), Atish T. Paul (2463508)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, Benzyloxy indole glyoxylamides, conophylline, geranyl, inhibition kinetics, molecular dynamics, pancreatic lipase, pre-clinical studies

العلاقة: https://figshare.com/articles/journal_contribution/Synthesis_molecular_modelling_i_in_vitro_i_and_i_in_vivo_i_evaluation_of_conophylline_inspired_novel_benzyloxy_substituted_indole_glyoxylamides_as_potent_pancreatic_lipase_inhibitors/14672833Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14672833.v1Test

المؤلفون: Juan C. Vázquez-Ucha (2747002), Diana Rodríguez (7860584), Cristina Lasarte-Monterrubio (7324745), Emilio Lence (1559887), Jorge Arca-Suarez (10722972), María Maneiro (2747005), Eva Gato (8503593), Astrid Perez (10722975), Marta Martínez-Guitián (10722978), Carlos Juan (54424), Antonio Oliver (195701), German Bou (2263219), Concepción González-Bello (1358856), Alejandro Beceiro (1559890)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Pharmacology, Infectious Diseases, Virology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, antimicrobial resistance, not-always-evident pocket, inhibition kinetics, Computational studies, chromosomal cephalosporinase AmpC, AmpC β- lactamase, deacylation rate, H 10 helix, antipseudomonal ceftazidime, Natural Resistance, tunnel-like site, AmpC enzymes, drug design, PAO 1, ampC expression levels, Bromide 2, indolizine adduct, Pseudomonas aeruginosa, nosocomial infections

العلاقة: https://figshare.com/articles/journal_contribution/6_Halopyridylmethylidene_Penicillin-Based_Sulfones_Efficiently_Inactivate_the_Natural_Resistance_of_Pseudomonas_aeruginosa_to_Lactam_Antibiotics/14510763Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00369.s001Test

المؤلفون: Zhuming Zhang, Kay Ahn, Pete Connolly, Javier Suarez, Gaochao Tian

المصدر: Biochemistry. 60:2407-2418

مصطلحات موضوعية: Drug, Time Factors, Pyridines, Dissociation rate, media_common.quotation_subject, Inhibition kinetics, Residence time (fluid dynamics), Biochemistry, Fluorescence, Mass Spectrometry, Etoricoxib, Drug Discovery, Humans, Furans, Enzyme Assays, media_common, Cyclooxygenase 2 Inhibitors, biology, Chemistry, Energetics, Limiting, Models, Theoretical, Oxygen, Kinetics, Celecoxib, Cyclooxygenase 2, Biophysics, biology.protein, Pyrazoles, Thermodynamics, Cyclooxygenase, Hydrogen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59a43285715b1335eab99c7d7e04c2bTest
https://doi.org/10.1021/acs.biochem.1c00294Test

المؤلفون: Tjusls China

مصطلحات موضوعية: Chemistry, Biophysics, Inhibition kinetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::84c61bb72068301a9d1b7af88bb7fe4fTest
https://doi.org/10.17504/protocols.io.7w9hph6Test

المؤلفون: Jinhyuk Lee, Yong-Doo Park, Yingying Xu, Qian Zhang, Jimin Zheng, Jun-Mo Yang

المصدر: Journal of Biomolecular Structure and Dynamics. 36:830-840

مصطلحات موضوعية: 0301 basic medicine, 030103 biophysics, Antioxidant, medicine.medical_treatment, Carthamus, Inhibition kinetics, Molecular Dynamics Simulation, Antioxidants, 03 medical and health sciences, Molecular dynamics, Chalcone, Non-competitive inhibition, Inhibitory kinetics, Structural Biology, medicine, Humans, Glycoside Hydrolase Inhibitors, Medicine, Chinese Traditional, Molecular Biology, biology, Chemistry, α glucosidase, Quinones, Active site, alpha-Glucosidases, General Medicine, biology.organism_classification, Kinetics, 030104 developmental biology, Diabetes Mellitus, Type 2, Biochemistry, biology.protein, Biophysics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c32c272166070ed11a860847b05e1b6Test
https://doi.org/10.1080/07391102.2017.1300544Test

المؤلفون: Katarzyna Guzik, Przemyslaw Grudnik, Bartosz J. Zieba, Krzysztof M. Zak, Grzegorz Dubin, Bogdan Musielak, Alexander Dömling, Tad A. Holak

المساهمون: Drug Design, Medicinal Chemistry and Bioanalysis (MCB)

المصدر: Oncotarget
Oncotarget, 7(21), 30323-30335. Impact Journals LLC

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Magnetic Resonance Spectroscopy, CLINICAL ACTIVITY, Programmed Cell Death 1 Receptor, drug protein binding, Plasma protein binding, ANTI-PD-L1 ANTIBODY, Pharmacology, Crystallography, X-Ray, drug research, THERAPY, B7-H1 Antigen, PROTEIN-PROTEIN INTERACTIONS, 0302 clinical medicine, Checkpoint inhibitor, binding affinity, conformational transition, Molecular Structure, Drug discovery, Chemistry, CHECKPOINT BLOCKADE, article, Ligand (biochemistry), Small molecule, unclassified drug, bms 8, Oncology, protein stability, MPDL3280A, 030220 oncology & carcinogenesis, protein protein interaction, CANCER-IMMUNOTHERAPY, immunotherapy, Immunotherapy, drug potency, Protein Binding, Signal Transduction, Research Paper, crystal structure, bms 37, medicine.drug_class, small molecule, Monoclonal antibody, Protein–protein interaction, Small Molecule Libraries, 03 medical and health sciences, Protein Domains, complex formation, inhibition kinetics, medicine, Humans, controlled study, human, nuclear magnetic resonance spectroscopy, STABILITY, drug targeting, bms 202, programmed death 1 receptor, molecular dynamics, NMR, programmed death 1 ligand 1, drug structure, checkpoint inhibitor, 030104 developmental biology, Targeted drug delivery, protein inhibitor, Biophysics, bms 242, drug synthesis, X-ray structure, INHIBITORS

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4077c489c1a3e54f918f43d3ca7d076cTest
https://hdl.handle.net/11370/66b38ebe-19cb-4ca3-bd38-d873a99853beTest

المؤلفون: Ni-Rung Liu, Menghsiao Meng, Jia-Yun Lin, Ka-Lik Cheng, Hua-Yang Lin, Jyung-Hurng Liu

المصدر: Biochemistry and Biophysics Reports

مصطلحات موضوعية: chemistry.chemical_classification, Glucose-6-phosphate isomerase, Autocrine Motility Factor, GTP', Biophysics, Inhibition kinetics, Biology, Biochemistry, chemistry.chemical_compound, Enzyme, chemistry, Affinity chromatography, Ribose, Denaturation (biochemistry), Glycolysis, Autocrine motility factor, GTP, Research Article, Phosphoglucose isomerase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df5bfb3a81bffbf89b24902c11843c3Test