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1دورية أكاديمية
المؤلفون: Zhengnian Li, Wenchao Lu, Tyler S. Beyett, Scott B. Ficarro, Jie Jiang, Jason Tse, Audrey Yong-Ju Kim, Jarrod A. Marto, Jianwei Che, Pasi A. Jänne, Michael J. Eck, Tinghu Zhang, Nathanael S. Gray
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Pharmacology, Cancer, Plant Biology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, acrylamide side chain, flipped binding mode, alternative binding mode, based covalent probe, ribose binding pocket, substituted pyrazolopyrimidine binds, binding pocket, covalent bond, oriented toward, kinase inhibitors, heterocyclic core, findings suggest, conformation analogous, c3 position, analogues feature
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01891.s002Test
https://figshare.com/articles/journal_contribution/ZNL0325_a_Pyrazolopyrimidine-Based_Covalent_Probe_Demonstrates_an_Alternative_Binding_Mode_for_Kinases/25127274Test -
2دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s001Test
https://figshare.com/articles/journal_contribution/Purification_of_HCMV_NEC_containing_His-UL50_and_Myc-UL53_with_size-exclusion_chromatography_/24584696Test -
3دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s002Test
https://figshare.com/articles/journal_contribution/HTRF_assays_for_inhibition_of_HSV-1_UL30_peptide-UL42_and_MCMV_M50-M53_interactions_/24584699Test -
4دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s003Test
https://figshare.com/articles/journal_contribution/GK1_does_not_interfere_with_the_HTRF_assay_/24584702Test -
5دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s004Test
https://figshare.com/articles/journal_contribution/Effect_of_GK2_on_HCMV_protein_expression_in_infected_cells_/24584705Test -
6دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
العلاقة: https://figshare.com/articles/journal_contribution/Design_and_testing_of_GK1_analogs_/24584744Test
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s017Test
https://figshare.com/articles/journal_contribution/Design_and_testing_of_GK1_analogs_/24584744Test -
7دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
العلاقة: https://figshare.com/articles/journal_contribution/List_of_primers_used_in_this_study_/24584741Test
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s016Test
https://figshare.com/articles/journal_contribution/List_of_primers_used_in_this_study_/24584741Test -
8دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s007Test
https://figshare.com/articles/journal_contribution/Activities_of_analogs_GKD4_GKD6_and_GKD9_/24584714Test -
9دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s005Test
https://figshare.com/articles/journal_contribution/Antiviral_activities_of_GK2_against_WT_HCMV_and_mutant_HCMV_C214S_/24584708Test -
10دورية أكاديمية
المؤلفون: Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. Coen
مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, docking studies suggest, acrylamide moiety predicted, nuclear egress complex, new antiviral drugs, compounds could serve, sterically hinder ul50, prevent nec formation, potential lacked activity, hcmv conferred resistance, gk1 also active, c214s substitution engineered, two compounds, nuclear rim, hcmv drugs, viral replication, viral proteins, two subunits, two inhibitors, small molecules, selectively inhibited
الإتاحة: https://doi.org/10.1371/journal.ppat.1011781.s011Test
https://figshare.com/articles/journal_contribution/Structures_of_two_compounds_containing_a_scaffold_similar_to_GK1_s_that_did_not_score_as_hits_/24584726Test