المؤلفون: Scotland Farley, Frank Stein, Per Haberkant, Fikadu G. Tafesse, Carsten Schultz

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Biotechnology, Cancer, Hematology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, two lipid species, single double bond, revealed significant differences, various cellular processes, prepared multifunctionalized derivatives, closely related sphinganine, cellular functions, well understood, trifunctional sphinganine, systematically map, signaling roles, signaling responses, protein interactomes, novel probes, new tool, elicit many, distinct roles, carbon backbone

العلاقة: https://figshare.com/articles/journal_contribution/Trifunctional_Sphinganine_A_New_Tool_to_Dissect_Sphingolipid_Function/25103537Test

الإتاحة: https://doi.org/10.1021/acschembio.3c00554.s001Test
https://figshare.com/articles/journal_contribution/Trifunctional_Sphinganine_A_New_Tool_to_Dissect_Sphingolipid_Function/25103537Test

المؤلفون: Dominic Helm, Sindhuja Sridharan, Frank Stein, Mandy Rettel, Nils Kurzawa, Mikhail M. Savitski, Tomi A Määttä

المصدر: Molecular Systems Biology, Vol 16, Iss 10, Pp n/a-n/a (2020)
Molecular Systems Biology

مصطلحات موضوعية: Protein Folding, Medicine (General), Proteome, Cell Survival, QH301-705.5, Fluorescent Antibody Technique, Context (language use), Biology, Protein aggregation, Proteomics, Mass Spectrometry, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Histones, 03 medical and health sciences, proteomics, R5-920, 0302 clinical medicine, Human proteome project, Humans, Biology (General), Nuclear protein, Solubility, 030304 developmental biology, Cell Nucleus, chemistry.chemical_classification, 0303 health sciences, General Immunology and Microbiology, Applied Mathematics, aggregation, Nuclear Proteins, Articles, heat shock, Amino acid, Molecular Weight, Isoelectric point, Computational Theory and Mathematics, chemistry, Protein Biosynthesis, disaggregation, Biophysics, thermal proteome profiling, General Agricultural and Biological Sciences, Heat-Shock Response, 030217 neurology & neurosurgery, Information Systems

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5935a77c810057cb60439af53b354ff7Test
https://doi.org/10.15252/msb.20209500Test

المؤلفون: Mandy Rettel, Mikhail M. Savitski, Tomi A Määttä, Frank Stein, Dominic Helm

مصطلحات موضوعية: chemistry.chemical_classification, Isoelectric point, chemistry, Biophysics, Human proteome project, Context (language use), Nuclear protein, Protein aggregation, Proteomics, Protein quality, Amino acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0a3724f06ee626a03971eccf7d6b99Test
https://doi.org/10.1101/2020.02.05.931675Test

المؤلفون: Michael Sattler, Dominic Helm, Hannah Girstmair, Franziska Tippel, Katarzyna M. Tych, Frank Stein, Philipp W. N. Schmid, Johannes Buchner, Per Haberkant, Abraham Lopez, Matthias Rief

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nat. Commun. 10:3626 (2019)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Folding, Cell biology, Saccharomyces cerevisiae Proteins, Protein Conformation, Science, Regulator, Biophysics, General Physics and Astronomy, 02 engineering and technology, Saccharomyces cerevisiae, Ligands, Biochemistry, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Protein structure, Stress, Physiological, Chaperones, Protein Isoforms, Amino Acid Sequence, HSP90 Heat-Shock Proteins, lcsh:Science, Adenosine Triphosphatases, Multidisciplinary, biology, Chemistry, Protein Stability, General Chemistry, 021001 nanoscience & nanotechnology, Hsp90, ddc, 030104 developmental biology, Proteostasis, Structural biology, Chaperone (protein), biology.protein, lcsh:Q, Protein folding, 0210 nano-technology, Sequence Alignment, Function (biology), Heat-Shock Response, Molecular Chaperones, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898d73ebfcf0c1efa3b1e9815327e528Test
https://pubmed.ncbi.nlm.nih.gov/31399574Test

المؤلفون: Athanasios Typas, André Mateus, Maike Schramm, Frank Stein, Peer Bork, Christoph W. Müller, Mikhail M. Savitski, Florence Baudin, Nils Kurzawa, Isabelle Becher, Natalie Romanov, Dominic Helm, Marie-Therese Mackmull, Amparo Andres-Pons, Martin Beck

المصدر: Cell

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Hot Temperature, Proteome, Cell, Mitosis, RNA polymerase II, Biology, General Biochemistry, Genetics and Molecular Biology, Mass Spectrometry, Article, 03 medical and health sciences, chemistry.chemical_compound, medicine, Cluster Analysis, Humans, Phosphorylation, 030102 biochemistry & molecular biology, Protein Stability, Cell Cycle, DNA, Cell cycle, Chromatin Assembly and Disassembly, Chromatin, 030104 developmental biology, medicine.anatomical_structure, chemistry, Solubility, Cardiovascular and Metabolic Diseases, biology.protein, Biophysics, RNA Polymerase II, thermal proteome profiling, Protein Processing, Post-Translational, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd370cb87d15d50efc71606ac536386Test
https://pubmed.ncbi.nlm.nih.gov/29706546Test

المؤلفون: Suihan Feng, Frank Stein, Carsten Schultz, Martina Schifferer

مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, Effector, Kinetics, Optogenetics, Enzyme assay, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Biochemistry, Biophysics, biology.protein, Chemically induced dimerization, Enzyme kinetics, Phosphatidylinositol, Protein Dimerization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9cb5e755fedafd06769bcaf84cfb1c53Test
https://doi.org/10.1016/bs.mie.2016.10.035Test

المؤلفون: Carsten Schultz, Frank Stein, Julio Saez-Rodriguez, Vibor Laketa, Suihan Feng, Anna Rutkowska, Ursula Klingmüller, Aidan MacNamara, Sofia Depner

المصدر: Angewandte Chemie International Edition. 53:6720-6723

مصطلحات موضوعية: General Medicine, General Chemistry, Lipid signaling, Phosphatidylinositol 3-Kinases, Tacrolimus, Catalysis, Kinetics, chemistry.chemical_compound, FKBP, Phosphatidylinositol Phosphates, chemistry, Biochemistry, Fluorescence microscope, Biophysics, Humans, Phosphorylation, Phosphatidylinositol, Signal transduction, Dimerization, Proto-Oncogene Proteins c-akt, PI3K/AKT/mTOR pathway, HeLa Cells, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1230f3e9b3584cb8000000ee63be95d4Test
https://doi.org/10.1002/anie.201402294Test

المؤلفون: Dmytro A. Yushchenko, Frank Stein, Christophe Mulle, André Nadler, Suihan Feng, Carsten Schultz, Rainer Müller, Mario Carta

المصدر: Nature Communications

مصطلحات موضوعية: Light, General Physics and Astronomy, chemistry.chemical_element, Calcium, Neurotransmission, General Biochemistry, Genetics and Molecular Biology, Neuronal Transmission, Article, Mice, Coumarins, Insulin-Secreting Cells, Animals, Humans, Calcium Signaling, Calcium signaling, Calcium metabolism, chemistry.chemical_classification, Neurons, Multidisciplinary, Arachidonic Acid, Chemistry, Biomolecule, Cell Membrane, Long-term potentiation, General Chemistry, Mice, Inbred C57BL, Membrane, Biochemistry, Biophysics, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4d443ee4992faf8fa0959d339bce77Test
http://europepmc.org/articles/PMC4703838Test

المؤلفون: Amanda Cobos-Correa, Frank Stein, Carsten Schultz

مصطلحات موضوعية: chemistry.chemical_classification, Proteases, biology, Organic Chemistry, Prodrug, Pharmacology, Cleavage (embryo), Biochemistry, In vitro, Enzyme assay, Enzyme, chemistry, In vivo, Drug Discovery, biology.protein, Biophysics, Peptide sequence

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a88b75659938501295eff64afb94e9dTest
https://europepmc.org/articles/PMC4025753Test/

المؤلفون: Suihan Feng, Rainer Mueller, Carsten Schultz, Gurleen Khandpur, Frank Stein, André Nadler, Dmytro A. Yushchenko

المصدر: Biophysical Journal. 108:417a

مصطلحات موضوعية: medicine.medical_specialty, Cell type, Insulin, medicine.medical_treatment, Biophysics, chemistry.chemical_element, Calcium, Calcium in biology, Cell biology, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, medicine, Glucose homeostasis, Arachidonic acid, Secretion, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba282f3cf94a76a3065c6d2cdc05cdbTest
https://doi.org/10.1016/j.bpj.2014.11.2286Test