المؤلفون: Jeanette Erdmann, Heribert Schunkert, Marijke Bijker-Schreurs, Ivana Bobeldijk-Pastorova, Lisette de Jong, Jan Albert Kuivenhoven, Alain J. van Gool

المصدر: Drug Discovery Today, 4, 25, 787-492
Drug Discovery Today, 25, 4, pp. 787-792
Drug Discovery Today, 25, 787-792

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Biomedical Research, business.industry, Cardiovascular research, MEDLINE, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Public relations, RISK LOCI, Europe, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug Development, Work (electrical), Cardiovascular Diseases, 030220 oncology & carcinogenesis, Drug Discovery, Humans, Molecular Targeted Therapy, business, Disease treatment, Independent research

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82536fdb6c077b3d8f625bcd3087cfeTest
https://doi.org/10.1016/j.drudis.2020.01.009Test

المؤلفون: Anita M. van den Hoek, Thomas Kelder, Ivana Bobeldijk-Pastorova, Suzan Wopereis, Peter Y. Wielinga, Lars Verschuren, Robert Kleemann, Chris T. Evelo, Karin Toet, Ben van Ommen, Maud Koek, Marjan van Erk, Linette Pellis, Nicole H.P. Cnubben, Teake Kooistra, Annie Jie

المساهمون: Bioinformatica, RS: NUTRIM - R4 - Gene-environment interaction, TNO Kwaliteit van Leven

المصدر: PloS one, 1, 5
PLOS ONE, 5(1):8817. Public Library of Science
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8817 (2010)

مصطلحات موضوعية: Male, Biomedical Research, Apolipoprotein E3, lcsh:Medicine, Adipose tissue, Biomedical Innovation, White adipose tissue, Fatty Acids, Nonesterified, Western blotting, Diabetes and Endocrinology/Obesity, Mice, RECEPTOR ANTAGONIST, Life, Nutrition/Obesity, lcsh:Science, Adiposity, Oligonucleotide Array Sequence Analysis, Glucose tolerance test, Computational Biology/Systems Biology, Multidisciplinary, medicine.diagnostic_test, GENE-EXPRESSION DATA, Fatty liver, food and beverages, MHR - Metabolic Health Research MSB - Microbiology and Systems Biology, Genetics and Genomics/Bioinformatics, C-REACTIVE PROTEIN, medicine.anatomical_structure, Blood, ADIPOSE-TISSUE, Physiology/Integrative Physiology, SKELETAL-MUSCLE, lipids (amino acids, peptides, and proteins), FATTY-ACIDS, EELS - Earth, Environmental and Life Sciences, Healthy Living, Research Article, medicine.medical_specialty, Blotting, Western, Computational Biology/Transcriptional Regulation, Mice, Transgenic, Carbohydrate metabolism, Biology, Computational Biology/Metabolic Networks, Insulin resistance, Internal medicine, medicine, Genetics, Animals, Diabetes and Endocrinology/Type 2 Diabetes, Obesity, ABDOMINAL ANEURYSM, lcsh:R, Physiology/Cardiovascular Physiology and Circulation, DNA microarray, Skeletal muscle, nutritional and metabolic diseases, NECROSIS-FACTOR-ALPHA, Lipid metabolism, Glucose Tolerance Test, medicine.disease, Fatty acid, MIGRATION INHIBITORY FACTOR, METABOLOMICS ANALYSIS, transgenic mouse, Endocrinology, Genetics and Genomics/Disease Models, physiology, lcsh:Q, Insulin Resistance

وصف الملف: application/x-www-form-urlencoded; charset=utf-8; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b17ca7d135d6692c01202b4ad4b611Test
https://doi.org/10.1371/journal.pone.0008817Test

المؤلفون: Ivana Bobeldijk, Uwe Thissen, Suzan Wopereis, Age K. Smilde, Ko Willems van Dijk, Teake Kooistra, Sjoerd A.A. van den Berg, Ben van Ommen, Robert Kleemann

المساهمون: Biosystems Data Analysis (SILS, FNWI), TNO Kwaliteit van Leven

المصدر: BMC Bioinformatics, Vol 10, Iss 1, p 52 (2009)
BMC Bioinformatics, 10. BioMed Central
BMC Bioinformatics, 10
BMC Bioinformatics

مصطلحات موضوعية: Multivariate statistics, Biomedical Research, Databases, Factual, Computer science, computer.software_genre, lcsh:Computer applications to medicine. Medical informatics, Biochemistry, Structural Biology, Partial least squares regression, Animals, Humans, Metabolomics, Biology, lcsh:QH301-705.5, Molecular Biology, Reliability (statistics), Interpretability, Models, Statistical, Applied Mathematics, Statistical model, Data science, Regression, Computer Science Applications, lcsh:Biology (General), lcsh:R858-859.7, Analysis of variance, Data mining, computer, Research Article

وصف الملف: application/pdf; application/x-www-form-urlencoded; charset=utf-8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dc6cbd6d4d03436a5c23565d7a5c71Test
https://hdl.handle.net/11245/1.312015Test

المؤلفون: Ivana Bobeldijk, Raymond Ramaker, Ian A. Macdonald, Sunil Kochhar, Elwin Verheij, Sabina Bijlsma, Age K. Smilde, Ben van Ommen

المساهمون: Epidemiology and Data Science, TNO Kwaliteit van Leven

المصدر: Analytical chemistry, 78(2), 567-574. American Chemical Society
Analytical Chemistry, 2, 78, 567-574

مصطلحات موضوعية: obesity, Statistical methods, computer.software_genre, regression analysis, Mass Spectrometry, Analytical Chemistry, Resampling, Statistics, Metabolic profiling, Data processing, Data reduction, article, Regression analysis, Postprandial Period, metabolomics, Lipids, univariate analysis, Europe, fat intake, validation study, Data Interpretation, Statistical, Data mining, Partial least-squares discriminant analysis (PLS-DA), Liquid chromatography, test meal, Biology, information processing, Metabolomics, statistical analysis, Human metabolomics, Humans, Biomedical research, human, Obesity, Least-Squares Analysis, Analytical research, plasma, Biomarker models, lean body weight, Univariate, Statistical model, discriminant analysis, Linear discriminant analysis, Dietary Fats, human tissue, Metabolism, Plasmas, Data pre-processing, computer, Chromatography, Liquid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b821f077bc13890488c3d3cbab817c20Test
https://pure.amc.nl/en/publications/largescale-human-metabolomics-studies-a-strategy-for-data-pre-processing-and-validationTest(8a38e125-0a8d-41bc-9daf-5faf353cec12).html