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المؤلفون: Kevin P. White, Peter Van Loo, Victor Aderoju, Lin Chen, Jiebiao Wang, Scott Mahan, Kenzie MacIsaac, Chibuzor Nkwodimmah, Dominic Fitzgerald, Olayiwola Oluwasola, Maura Macomber, Markus Riester, Adewunmi Adeoye, Artur Veloso, Kerstin Haase, Dezheng Huo, Christopher O. Olopade, Jordi Barretina, Mobolaji A. Oludara, Jigyasa H. Tuteja, Abiodun Popoola, A. Jason Grundstad, Ryan Johnson, Shengfeng Wang, Bryce Hwang, Temidayo O. Ogundiran, Jing Zhang, Olufunmilayo I. Olopade, Odunayo Akinyele, Babajide Okedere, Jason J. Pitt, Folusho Omodele, Oladosu Ojengbede, Michael Morrissey, Esther Obasi, Mustapha Akanji Ajani, Wendy Winckler, Toshio F. Yoshimatsu, Ayodele Sanni, Barbara L. Weber, Dimitris Papoutsakis, Galina Khramtsova, Chinedum P. Babalola, Adeyinka G. Falusi, Bisola Famooto, Rebecca Leary, Elisabeth Sveen, Yonglan Zheng, Abayomi Odetunde, Adeyinka Ademola, W Clayton, Nasiru Ibrahim, Emma Labrot, John Obafunwa
المصدر: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, Biology, Genome, General Biochemistry, Genetics and Molecular Biology, Article, CDH1, 03 medical and health sciences, Underserved Population, Breast cancer, medicine, skin and connective tissue diseases, lcsh:Science, Gene, Exome, Genetics, Multidisciplinary, Nigerians, GATA3, General Chemistry, medicine.disease, 3. Good health, 030104 developmental biology, biology.protein, lcsh:Q
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7d8d8463017157e7b4bf0fef81ba05Test
http://europepmc.org/articles/PMC6191428Test -
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المؤلفون: Catherine Tribouley, Markus Riester, Eneida R. Nemecek, Serafino Pantano, Michael R. Verneris, Henrique Bittencourt, Piotr Pierog, Michael Morrissey, Stella M. Davies, Stephan A. Grupp, Jochen Buechner, Jeffrey A. Engelman, Xia Han, Hidefumi Hiramatsu, Barbara De Moerloose, Jennifer Brogdon, Muna Qayed, Elena Orlando, Patricia A. Wood, Hans Bitter, John E. Levine, Michael Boyer, Kevin Nguyen, Rebecca Leary, Wendy Winckler
المصدر: Nature medicine. 24(10)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, T-Lymphocytes, Antigens, CD19, Receptors, Antigen, T-Cell, Loss of Heterozygosity, medicine.disease_cause, Immunotherapy, Adoptive, General Biochemistry, Genetics and Molecular Biology, CD19, Loss of heterozygosity, 03 medical and health sciences, 0302 clinical medicine, Antigen, medicine, Humans, Receptor, Mutation, Receptors, Chimeric Antigen, biology, hemic and immune systems, General Medicine, Immunotherapy, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Chimeric antigen receptor, Transmembrane domain, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, biology.protein, Cancer research
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9e3d52d5bee88e031cd1aa3b42c6c7Test
https://pubmed.ncbi.nlm.nih.gov/30367128Test -
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المؤلفون: Robert C. Onofrio, Gregory Y. Lauwers, Todd R. Golub, Wendy Winckler, Bryan C. Fuchs, Yujin Hoshida, Lan Wei, Andrew Crenshaw, Tsutomu Fujii, Bradley K. Taylor, Suguru Yamada, Christopher M. McGinn, Supriya Gupta, Peter Caravan, Nabeel Bardeesy, Danielle K. DePeralta, Toshihiko Kuroda, Kenneth K. Tanabe, Xintong Chen, Michael Lanuti, Anthony D. Schmitt
المصدر: Hepatology. 59:1577-1590
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Cirrhosis, Hepatology, Biology, medicine.disease, digestive system diseases, Liver disease, Epidermal growth factor, Hepatocellular carcinoma, medicine, Cancer research, biology.protein, Hepatic stellate cell, Epidermal growth factor receptor, Erlotinib, Erlotinib Hydrochloride, neoplasms, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bec42f4dd96fac8b818a51fc07d54966Test
https://doi.org/10.1002/hep.26898Test -
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المؤلفون: Ding Li, Esther Elishaev, Linda Dao, Juok Cho, Alexei Protopopov, Heather Schmidt, Tod D. Casasent, Bobbie S. Gostout, P.J. DiSaia, Jacqueline E. Schein, J. Todd Auman, Jay Bowen, S. Onur Sumer, Beth Y. Karlan, Gordon Saksena, Prachi Kothiyal, Robert E. Pyatt, Theodore C. Goldstein, Lisle E. Mose, Paul J. Goodfellow, Brenda Ayala, Nilsa C. Ramirez, Thomas Barr, Payal Sipahimalani, Gordon B. Mills, Rebecca Carlsen, Linda Van Le, Andy Chu, Peter W. Laird, Russell Broaddus, Helga B. Salvesen, Sam Ng, Cyriac Kandoth, Christopher Adams, Yiling Lu, Donghui Tan, Peter White, Lori Boice, Saianand Balu, Daniel DiCara, Robert A. Holt, Christopher C. Benz, Shi Yan, Joel S. Parker, Jessica Frick, Adrian Ally, Boris Winterhoff, Pamela M. Pollock, Patrick Plettner, Ethan Cerami, Angela Tam, Katherine A. Hoadley, Melissa Hart-Kothari, Robert C. Onofrio, John N. Weinstein, Sheila Reynolds, David Haussler, Kristian Cibulskis, Charles M. Perou, Timothy J. Triche, Rehan Akbani, Jeff Roach, Michael Mayo, Ranabir Guin, W. Kimryn Rathmell, Carmen Helsel, Junyuan Wu, Will Mallard, Nandita Barnabas, Todd Pihl, Ruibin Xi, Nianxiang Zhang, David Mallery, Douglas A. Levine, Aaron D. Black, David I. Heiman, Sugy Kodeeswaran, Lynda Chin, Guoyan Liu, Mark E. Borowsky, Daniel J. Weisenberger, Yuexin Liu, Hailei Zhang, Kenna R. Mills Shaw, Anna K. Unruh, Andrew Berchuck, Michael Button, Noreen Dhalla, Bryan Hernandez, Rayna K. Matsuno, David G. Mutch, Chen Wang, Teresa R. Tabler, Yaron S.N. Butterfield, Jeff Gentry, Stuart R. Jefferys, Thomas Grossman, Kelley Kneile, Fanny Dao, Scot Waring, Barbara Tabak, Eric E. Snyder, Eric S. Lander, Richard A. Moore, David J. Dooling, David Van Den Berg, Jiabin Tang, Piotr A. Mieczkowski, Victoria Blanc, Wei Zhang, Inanc Birol, Harkness Kuck, Mathew G. Soloway, Johanna Gardner, Gary Witkin, Sahil Seth, Heidi J. Sofia, B. Arman Aksoy, Nikolaus Schultz, Marco A. Marra, Andrew D. Cherniack, D L Rotin, Anders Jacobsen, Erik Zmuda, Candace Carter, Christina Yau, Stephen C. Benz, Alexander A. Green, Michael D. Topal, Jean MacKenzie, Elena Nemirovich-Danchenko, Nicholas J. Petrelli, Dana Nicholson, Eve Shinbrot, Han Liang, Rameen Beroukhim, Charlenia Berry-Green, Kristin G. Ardlie, Joan Pontius, David Pot, Ari B. Kahn, Marc T. Goodman, Yevgeniy Antipin, Christopher Szeto, Jianhua Zhang, Ilya Shmulevich, Lori Huelsenbeck-Dill, Steven J.M. Jones, Carrie Sougnez, Kristen M. Leraas, Pei Lin, Robert A. Soslow, Erin Curley, Leigh B. Thorne, Hye Jung E. Chun, Michael S. Lawrence, Michelle O'Laughlin, Moiz S. Bootwalla, Lixing Yang, Mark A. Jensen, Rajiv Dhir, David A. Wheeler, C. Blake Gilks, Jianjiong Gao, Lisa Wise, Giovanni Ciriello, Joelle Kalicki-Veizer, Shaowu Meng, Mei Huang, Elaine R. Mardis, Faina Bogomolniy, Kai Ye, Jenny Lester, Lihua Zou, Hollie A. Harper, Robert Edwards, Ronglai Shen, Xiaojia Ren, Nils Weinhold, Harshad S. Mahadeshwar, Sandra Orsulic, Tom Bodenheimer, Zhenlin Ju, Chris Wakefield, Scott Frazer, John M. S. Bartlett, Gideon Dresdner, Hui Shen, Deepak Srinivasan, Aaron Hobensack, Cynthia McAllister, Marc Ladanyi, Tanja Davidsen, Lucinda Fulton, Michael D. McLellan, Richard K. Wilson, Zeng Dong, Olga Potapova, Sean C. Dowdy, Rui Jing, Kristin K. Zorn, Robert S. Fulton, Matti Annala, Chris Sander, Michael S. Noble, Benjamin Gross, Janae V. Simons, Phillip H. Lai, Laura Monovich, Andrew J. Mungall, Peter J. Park, Fedor Moiseenko, Liming Yang, Gad Getz, John Deardurff, Matthew Meyerson, Jeremy Parfitt, A. Gordon Robertson, Bradley M. Broom, Blaise A. Clarke, Greg Eley, Jennifer O. Fisher, Andrey Sivachenko, Narciso Olvera, Carrie Hirst, Adam M. Farkas, Karuna Garg, Wendy Winckler, Eric Chuah, Stacey Gabriel, Michael E. Carney, Stephen B. Baylin, Doug Voet, Miruna Balasundaram, Christine Czerwinski, Daphne W. Bell, Richard Varhol, Alexandra Meuter, Alan P. Hoyle, Darlene Lee, Elizabeth Buda, Li Ding, Xingzhi Song, Steven E. Schumacher, Anna L. Chu, Attila Teoman, Mary Iacocca, Semin Lee, Rileen Sinha, Itai Pashtan, Haiyan I. Li, Mikhail Abramov, Mark S. Guyer, Robert Penny, Margi Sheth, Scott L. Carter, Corbin D. Jones, Michael J. Birrer, Julie M. Gastier-Foster, D. Neil Hayes, Nathan Vanhoose, Brenda Rabeno, Raju Kucherlapati, Martin L. Ferguson, Joshua M. Stuart, Steve E. Kalloger, Mark G. Cadungog, Petar Stojanov, Tara M. Lichtenberg, Bradley A. Ozenberger, Angela Hadjipanayis, Barry S. Taylor, Boris Reva
المساهمون: Massachusetts Institute of Technology. Department of Biology, Lander, Eric S., Park, Peter J.
المصدر: Nature
PMCمصطلحات موضوعية: DNA Copy Number Variations, endocrine system diseases, ARID1A, DNA Mutational Analysis, Breast Neoplasms, Biology, medicine.disease_cause, Article, Uterine serous carcinoma, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, PTEN, Exome, Poly-ADP-Ribose Binding Proteins, neoplasms, 030304 developmental biology, Chromosome Aberrations, Ovarian Neoplasms, 0303 health sciences, Endometrial intraepithelial neoplasia, Multidisciplinary, Genome, Human, Microsatellite instability, DNA Polymerase II, Genomics, medicine.disease, Molecular biology, female genital diseases and pregnancy complications, Endometrial Neoplasms, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Serous fluid, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, biology.protein, Female, KRAS, Signal Transduction, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26da1e5ab2b011629d8910cfd5a4a5b1Test
https://doi.org/10.1038/nature12113Test -
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المؤلفون: Michael S. Lawrence, Kwok-Kin Wong, D. R. Mani, Xiaohong Zhang, Heidi Greulich, Tzu-Hsiu Chen, Bethany Kaplan, Gad Getz, Alice H. Berger, Michael J. Eck, Se-Hoon Lee, Jacob D. Jaffe, Lauren Ambrogio, David A. Frank, Philipp Mertins, Wendy Winckler, Shantanu Banerji, Steven A. Carr, Jinghui Zhang, Matthew Meyerson, Nam Pho, Marcin Imielinski, William C. Hahn, Cai-Hong Yun, Sarah R. Walker, Jeonghee Cho, Kumiko E. Tanaka, Rachel G. Liao
المصدر: Proceedings of the National Academy of Sciences. 109:14476-14481
مصطلحات موضوعية: Lung Neoplasms, Receptor, ErbB-2, Immunoblotting, Adenocarcinoma of Lung, Adenocarcinoma, SH2 domain, Tropomyosin receptor kinase C, Receptor tyrosine kinase, Mice, chemistry.chemical_compound, Cell Movement, Tandem Mass Spectrometry, Animals, Cloning, Molecular, Phosphorylation, Alleles, DNA Primers, Multidisciplinary, biology, Tyrosine phosphorylation, Biological Sciences, Molecular biology, Protein Structure, Tertiary, Retroviridae, chemistry, Mutation, ROR1, NIH 3T3 Cells, biology.protein, Dimerization, Tyrosine kinase, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase Src
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c515f2e4b7375040a3b03368ee396169Test
https://doi.org/10.1073/pnas.1203201109Test -
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المؤلفون: Casey Gates, William M. Lin, Whei Feng, Levi A. Garraway, Matthew Meyerson, Todd R. Golub, Jennifer M. Marmion, F. Stephen Hodi, Meenhard Herlyn, William R. Sellers, Rameen Beroukhim, Gad Getz, Roman K. Thomas, Heidi Greulich, Wendy Winckler, Glenn Dranoff, Alissa C. Baker, Reinhard Dummer, Elisabeth Laine, Hsiuyi Tseng
المساهمون: University of Zurich, Garraway, L A
المصدر: Cancer research
مصطلحات موضوعية: Cancer Research, Loss of Heterozygosity, 610 Medicine & health, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Tensin, PTEN, Cluster Analysis, Humans, 1306 Cancer Research, Receptor, Fibroblast Growth Factor, Type 1, Protein kinase A, Extracellular Signal-Regulated MAP Kinases, Melanoma, 030304 developmental biology, Chromosome Aberrations, 0303 health sciences, Chromosomes, Human, Pair 10, Gene Expression Profiling, PTEN Phosphohydrolase, 10177 Dermatology Clinic, Cancer, DNA, Neoplasm, medicine.disease, Gene expression profiling, Imatinib mesylate, Oncology, 030220 oncology & carcinogenesis, Cutaneous melanoma, Cancer research, biology.protein, 2730 Oncology, raf Kinases, Chromosome Deletion, Mitogen-Activated Protein Kinases, Algorithms
وصف الملف: Lin_Paper_20070616.pdf - application/pdf; Lin_CancRes_2008V.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb528b9445923c15abd8b1842c81a8f1Test
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المؤلفون: Michael Morrissey, Matt Hims, Rebecca Leary, S Hirawat, Nadia Solovieff, Cristian Massacesi, Emmanuelle di Tomaso, C. Germa, Wendy Winckler, Derek Y. Chiang, Stefan J. Scherer
المصدر: Molecular Cancer Therapeutics. 14:LB-A05
مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Cancer Research, biology, medicine.disease, Bioinformatics, medicine.disease_cause, DNA sequencing, genomic DNA, Breast cancer, Oncology, Cell-free fetal DNA, medicine, Cancer research, biology.protein, PTEN, KRAS, Lung cancer
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ae961f4761acd7001510e592eb9096d6Test
https://doi.org/10.1158/1535-7163.targ-15-lb-a05Test -
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المؤلفون: Andrey Sivachenko, Robert C. Onofrio, Mirjam Blattner, Naoki Kitabayashi, Daniel Auclair, Christopher E. Barbieri, Nicolas Stransky, Kristin Ardlie, Ashutosh K. Tewari, Francesca Demichelis, Petar Stojanov, Matthew Meyerson, Thomas A. White, Jean Philippe Theurillat, Wasay M. Hussain, Sung Suk Chae, Theresa Y. MacDonald, Todd R. Golub, Juan Miguel Mosquera, Levi A. Garraway, Colm Morrissey, Peter J. Wild, Eliezer M. Van Allen, Candace Guiducci, Alex H. Ramos, Elizabeth Nickerson, Michelle C Redman, Gad Getz, Peter S. Nelson, Sylvan C. Baca, Kristian Cibulskis, Kyung Park, Holger Moch, Michael S. Lawrence, Scott L. Carter, Gunther Boysen, Karen Sheikh, Stacey Gabriel, Eric S. Lander, Terry Vuong, Wendy Winckler, Mark A. Rubin, Gordon Saksena, Douglas Voet, Niels J. Rupp, Philip W. Kantoff
المساهمون: Massachusetts Institute of Technology. Department of Biology, Lander, Eric S.
المصدر: PMC
مصطلحات موضوعية: Hepatocyte Nuclear Factor 3-alpha, Male, Mediator Complex, biology, Prostatic Neoplasms, Cancer, Sequence Analysis, DNA, Chromoplexy, SPOP, medicine.disease_cause, medicine.disease, Research Highlight, Prostate cancer, Mutation, Genetics, medicine, Cancer research, biology.protein, Humans, PTEN, Exome, Carcinogenesis, Microtubule-Associated Proteins, Exome sequencing
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155195c3be5acf1dae6001bff4c1b366Test
http://hdl.handle.net/1721.1/84658Test -
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المؤلفون: Douglas Voet, Candace Guiducci, Marjorie Romkes, Michael F. Berger, Daniel Auclair, Wendy Winckler, Petar Stojanov, Gad Getz, Raja R. Seethala, Matthew Meyerson, Levi A. Garraway, Joel L. Weissfeld, Alfredo Hidalgo-Miranda, Claudia Rangel-Escareño, Todd R. Golub, Scott L. Carter, Erica Shefler, Maria L. Cortes, Kristian Cibulskis, Andrey Sivachenko, Juan Carlos Fernández-López, Jorge Melendez-Zajgla, Robert C. Onofrio, Aaron D. Tward, Kristin Ardlie, Jennifer R. Grandis, Alex H. Ramos, Lin Wang, Nicolas Stransky, Gregory Kryukov, Michael S. Lawrence, Stacey Gabriel, Aleksandar Kostic, Ann Marie Egloff, Aaron McKenna, Gordon Saksena, Eric S. Lander, Melissa Parkin, Carrie Sougnez
المساهمون: Massachusetts Institute of Technology. Department of Biology, Lander, Eric S.
المصدر: PubMed Central
مصطلحات موضوعية: Squamous Differentiation, Apoptosis, Malignancy, medicine.disease_cause, Article, CDKN2A, Tobacco, medicine, PTEN, Humans, Point Mutation, HRAS, Neoplasms, Squamous Cell, Papillomaviridae, Receptor, Notch1, neoplasms, Sequence Deletion, Multidisciplinary, biology, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Papillomavirus Infections, Smoking, Cell Differentiation, Exons, Sequence Analysis, DNA, medicine.disease, biology.organism_classification, Head and neck squamous-cell carcinoma, stomatognathic diseases, Head and Neck Neoplasms, Mutation, Cancer research, biology.protein, Carcinoma, Squamous Cell, Carcinogenesis, Algorithms, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73611bdf73e01b70c451bdf8e7bc24f3Test
https://pubmed.ncbi.nlm.nih.gov/21868662Test -
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المؤلفون: Scott Mahan, Gad Getz, Antje Sucker, Douglas Voet, Gordon Saksena, Rui Jing, Rhamy Zeid, Michael S. Lawrence, Jennifer A. Wargo, Xiaojia Ren, Scott L. Carter, Stephan N. Wagner, Jordi Barretina, Todd R. Golub, Nikhil Wagle, Trevor J. Pugh, Alexei Protopopov, Stacey Gabriel, Hailei Zhang, Wendy Winckler, Jennifer Baldwin, Kristian Cibulskis, Nicolas Stransky, Papia Ghosh, Yotam Drier, Alex H. Ramos, Elizabeth Nickerson, Levi A. Garraway, Timothy P. Heffernan, Meredith A. Singer, Melissa Parkin, Michael F. Berger, Elena S Ivanova, Matthew Meyerson, Dirk Schadendorf, Lynda Chin, Carrie Sougnez, Eric S. Lander, Yonathan Lissanu Deribe, Robert C. Onofrio, Lauren Ambrogio, Andrey Sivachenko, Daniel Auclair, Ian R. Watson, Kristin G. Ardlie, Eran Hodis, Petar Stojanov, Timothy Fennell
المساهمون: Massachusetts Institute of Technology. Department of Biology, Whitehead Institute for Biomedical Research, Lander, Eric S.
المصدر: eLife
PMC
Natureمصطلحات موضوعية: driver mutations, Ultraviolet Rays, DNA Mutational Analysis, Medizin, Biology, medicine.disease_cause, Article, Chromosome Breakpoints, medicine, melanoma, PTEN, Guanine Nucleotide Exchange Factors, Humans, Mutation frequency, Human Biology and Medicine, Gene, mouse, Mutation, cancer genomics, Multidisciplinary, Genome, Human, Melanoma, Point mutation, methodology, Oncogenes, Cell Biology, medicine.disease, Molecular biology, Gene Expression Regulation, Neoplastic, Mutagenesis, Registered Report, biology.protein, Sunlight, Reproducibility Project: Cancer Biology, Melanocytes, Human genome, Ectopic expression, DNA Damage
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9701c9c4ae74a8f7ad513ae832f599dcTest
https://pubmed.ncbi.nlm.nih.gov/25490935Test