-
1
المؤلفون: Bhavesh D. Kevadiya, Rolen M. Quadros, R. Lee Mosley, Krista L. Namminga, Katherine E. Olson, Channabasavaiah B. Gurumurthy, Howard E. Gendelman, Ju Gao, Pravin Yeapuri, Jonathan Herskovitz, Yaman Lu, Yutong Liu, Jatin Machhi, Larisa Y. Poluektova, Emma Foster, Liang Jingjing, Xinglong Wang, Mai Mohamed Abdelmoaty, Rupesh V. Chikhale, Tomomi Kiyota
المصدر: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-23 (2021)مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Amyloid beta, T cell, Immunology, Alzheimer’s disease (AD), Mice, Transgenic, Regulatory T cell (Treg), T-Lymphocytes, Regulatory, APP/PS1 transgenic mice, Presenilin, Amyloid beta-Protein Precursor, Mice, Cellular and Molecular Neuroscience, Immune system, Effector T cell (Teff), Alzheimer Disease, Presenilin-1, medicine, Amyloid precursor protein, Animals, Amyloid beta (Aβ), RC346-429, Neuroinflammation, Inflammation, biology, Microglia, Research, General Neuroscience, Neurodegeneration, Amyloidosis, Th1 Cells, medicine.disease, medicine.anatomical_structure, Neurology, biology.protein, Th17 Cells, Neurology. Diseases of the nervous system, Cognition Disorders
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbd314681c10d92a7777efeb5c26567Test
https://doi.org/10.1186/s12974-021-02308-7Test -
2
المصدر: Bioorganic chemistry. 115
مصطلحات موضوعية: Enoyl-acyl carrier protein reductase, Antitubercular Agents, Microbial Sensitivity Tests, Reductase, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Humans, Inhibins, Molecular Biology, Fatty acid synthesis, chemistry.chemical_classification, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Drug discovery, INHA, Organic Chemistry, Mycobacterium tuberculosis, Acyl carrier protein, Enzyme, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e398c0a0f3b48b9d086508aa0c6b61Test
https://pubmed.ncbi.nlm.nih.gov/34392175Test -
3
المؤلفون: Sudesh N. Gaidhani, Shailendra S. Gurav, B. M. Patil, Bhavana Srivastava, Rupesh V. Chikhale, Yadu Nandan Dey, Pukar Khanal, Rajesh B. Patil, Manish M. Wanjari
المصدر: RSC Advances
مصطلحات موضوعية: 0303 health sciences, Chemokine, Protease, biology, General Chemical Engineering, Andrographolide, Systems biology, medicine.medical_treatment, General Chemistry, AutoDock, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Biochemistry, 030220 oncology & carcinogenesis, biology.protein, medicine, Rap1, Cytotoxicity, PubChem, 030304 developmental biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c1afca2a8cbba254cc7c7b997a1ad1Test
https://ueaeprints.uea.ac.uk/id/eprint/79245Test/ -
4
المؤلفون: Pritee Chunarkar Patil, Pooja Balasaheb Shinde, Shovonlal Bhowmick, Saikh Mohammad Wabaidur, Etidal Alfantoukh, Rupesh V. Chikhale, Ataul Islam
مصطلحات موضوعية: 0301 basic medicine, Pharmacoinformatics, Integrase inhibitor, Integrase Inhibitors, Computational biology, HIV Integrase, Molecular Dynamics Simulation, Biochemistry, Molecular mechanics, 03 medical and health sciences, Molecular dynamics, 0302 clinical medicine, Structural Biology, Virtual screening, biology, Molecular Structure, Chemistry, Organic Chemistry, Ligand (biochemistry), Chemical space, Integrase, Molecular Docking Simulation, Computational Mathematics, 030104 developmental biology, 030220 oncology & carcinogenesis, Drug Design, biology.protein
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364853a0bef5e870ff722b301ac5f48bTest
https://ueaeprints.uea.ac.uk/id/eprint/75764Test/ -
5
المصدر: Journal of Molecular Structure. 1247:131331
مصطلحات موضوعية: Drug, chemistry.chemical_classification, ATP synthase, biology, Chemistry, media_common.quotation_subject, Organic Chemistry, Biological activity, Drug resistance, biology.organism_classification, Analytical Chemistry, Inorganic Chemistry, chemistry.chemical_compound, Enzyme, Biochemistry, biology.protein, Structure–activity relationship, Adenosine triphosphate, Spectroscopy, Mycobacterium, media_common
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6a77084c776b8d5e5ad2a7f43cffb3ceTest
https://doi.org/10.1016/j.molstruc.2021.131331Test -
6
المؤلفون: Rupesh V. Chikhale, Kapilkumar Mehta, Deekshi Angira, Vijay Thiruvenkatam, Richard A. Bryce
المصدر: Angira, D, Chikhale, R, Mehta, K, Bryce, R A & Thiruvenkatam, V 2019, ' Tracing the GSAP–APP C-99 Interaction Site in the β-Amyloid Pathway Leading to Alzheimer’s Disease ', ACS Chemical Neuroscience, vol. 10, no. 8, pp. 3868-3879 . https://doi.org/10.1021/acschemneuro.9b00332Test
مصطلحات موضوعية: Physiology, Cognitive Neuroscience, Plaque, Amyloid, Peptide, Molecular Dynamics Simulation, Biochemistry, Amyloid beta-Protein Precursor, 03 medical and health sciences, Maltose-binding protein, 0302 clinical medicine, Alzheimer Disease, β amyloid, GAMMA-SECRETASE-ACTIVATING PROTEIN, mental disorders, Humans, Ternary complex, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Amyloid beta-Peptides, biology, Chemistry, Interaction site, Isothermal titration calorimetry, Cell Biology, General Medicine, Cell biology, Dissociation constant, biology.protein, 030217 neurology & neurosurgery
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf4fd401f87104c7b742ce58cf47943Test
https://pubs.acs.org/doi/10.1021/acschemneuro.9b00332Test -
7
المؤلفون: Chaitanya Sadashiv Jangam, Rupesh V. Chikhale, Shovonlal Bhowmick, Saikh Mohammad Wabaidur, Pritee Chunarkar Patil, Lomate Dhanraj Bharatrao, Nora Abdullah AlFaris, Jozaa Zaidan ALTamimi, Rekha Dhondiram Chorge, Ataul Islam
المصدر: Computational Biology and Chemistry. 83:107136
مصطلحات موضوعية: 0301 basic medicine, Pharmacoinformatics, Antitubercular Agents, Microbial Sensitivity Tests, Molecular Dynamics Simulation, Biochemistry, Mycobacterium tuberculosis, 03 medical and health sciences, 0302 clinical medicine, Bacterial Proteins, Structural Biology, Humans, Enzyme Inhibitors, Catalase-peroxidase, chemistry.chemical_classification, Virtual screening, biology, Chemistry, Organic Chemistry, Active site, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, biology.organism_classification, Chemical space, Molecular Docking Simulation, Computational Mathematics, 030104 developmental biology, Enzyme, Peroxidases, 030220 oncology & carcinogenesis, biology.protein, Lipinski's rule of five, bacteria
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bec43ef70573718cc15390eace27dd0Test
https://doi.org/10.1016/j.compbiolchem.2019.107136Test -
8
المؤلفون: Rajan Kumar Choudhary, Nikhil Gadewal, Sonali G. Thorat, Pramod B. Khedekar, Rupesh V. Chikhale
المصدر: Bioorganic chemistry. 77
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cell Survival, Antineoplastic Agents, 01 natural sciences, Biochemistry, Receptor tyrosine kinase, Rats, Sprague-Dawley, 03 medical and health sciences, Structure-Activity Relationship, Pharmacokinetics, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Cancer, Protein-Tyrosine Kinases, medicine.disease, 0104 chemical sciences, Bioavailability, Rats, Dasatinib, 030104 developmental biology, HEK293 Cells, Pyrimidines, Drug Design, biology.protein, Cancer research, Pharmacophore, Tyrosine kinase, Intracellular, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f8f9ddd563c38a11aa3b0526758ad1Test
https://pubmed.ncbi.nlm.nih.gov/29342447Test -
9
المؤلفون: Sunil S. Menghani, Rupesh V. Chikhale, Ramavath Babu, Ratnadeep Bansode, Melath V. Rajasekharan, G. Bhargavi, Pramod B. Khedekar, Nazira Karodia, Anant Paradkar
المصدر: European journal of medicinal chemistry. 96
مصطلحات موضوعية: Steric effects, Models, Molecular, Quantitative structure–activity relationship, Stereochemistry, Antitubercular Agents, Microbial Sensitivity Tests, Crystallography, X-Ray, chemistry.chemical_compound, Structure-Activity Relationship, Bacterial Proteins, Drug Discovery, Benzothiazoles, Pharmacology, biology, Dose-Response Relationship, Drug, Molecular Structure, Hydrogen bond, Organic Chemistry, Active site, General Medicine, Mycobacterium tuberculosis, Combinatorial chemistry, Alcohol Oxidoreductases, Pyrimidines, Benzothiazole, chemistry, Docking (molecular), Drug Design, biology.protein, Drug receptor, Pharmacophore
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11be6a3da72ea5630e514f01326284eTest
https://pubmed.ncbi.nlm.nih.gov/25874329Test -
10
المصدر: BMC Infectious Diseases
مصطلحات موضوعية: Pathology, medicine.medical_specialty, biology, business.industry, In silico, Human immunodeficiency virus (HIV), Salvage therapy, medicine.disease_cause, Raltegravir, Integrase, Lens epithelium-derived growth factor, Infectious Diseases, Poster Presentation, medicine, Cancer research, biology.protein, Antiretroviral medication, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ab414ec2741042191ef99b79d052e4Test