المؤلفون: Dillon H. Miles, Ada Chen, Manmohan Reddy Leleti, Divyank Soni, Stephen W Young, Artur K. Mailyan, Kenneth V. Lawson, Stefan G Shaqfeh, Ehesan U. Sharif, Jenna L. Jeffrey, Jesus Banuelos, Xuelei Yan, Samuel L Drew, Kimberline Gerrick, Nigel Walker, Puja Dhanota, Lixia Jin, Jay P. Powers, Elaine Ginn, Guillaume Mata, Kent Wong, Hema Singh, Jeremy Fournier, Joel W. Beatty, Ulrike Schindler, Amber Pham, Matthew J. Walters, Jie Chen, Cesar Meleza, Xiaoning Zhao, Nell Narasappa

المصدر: Journal of Medicinal Chemistry. 65:1418-1444

مصطلحات موضوعية: Male, Pyrazolopyrimidine, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Immune system, Amide, Drug Discovery, Animals, Class Ib Phosphatidylinositol 3-Kinase, Humans, Structure–activity relationship, Potency, Phosphoinositide-3 Kinase Inhibitors, Phosphoinositide 3-kinase, biology, Amides, Phenotype, In vitro, Rats, Molecular Docking Simulation, Pyrimidines, chemistry, Biochemistry, Drug Design, biology.protein, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37aec4464f4375ff8b99d31a40b9e89Test
https://doi.org/10.1021/acs.jmedchem.1c01153Test

المؤلفون: J. Bennett Addison, Oliver Fiehn, Shen Tong, Philipp Zerbe, Puja Dhanota, Prema Sambandaswami Karunanithi

المصدر: BMC Plant Biology, Vol 19, Iss 1, Pp 1-14 (2019)
BMC Plant Biology
BMC plant biology, vol 19, iss 1

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Marrubium vulgare, Plant Biology, Plant Science, Marrubiin, Medicinal, 01 natural sciences, Substrate Specificity, Hydroxylation, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Diterpene synthase, Gene Expression Regulation, Plant, Diterpenoid biosynthesis, lcsh:Botany, Plant Proteins, 2. Zero hunger, biology, Cytochrome P450 monooxygenase, food and beverages, Plants, Plants, Genetically Modified, lcsh:QK1-989, Biochemistry, Diterpenes, Biotechnology, Marrubium, Research Article, Crop and Pasture Production, Plant Biology & Botany, Genetically Modified, Plant natural products, Flowers, Saccharomyces cerevisiae, Microbiology, Gas Chromatography-Mass Spectrometry, Metabolic engineering, 03 medical and health sciences, Isomerism, Biosynthesis, Tobacco, Genetics, Plants, Medicinal, Gene Expression Profiling, Cytochrome P450, Plant, Monooxygenase, biology.organism_classification, Terpenoid, Plant Leaves, 030104 developmental biology, Gene Expression Regulation, chemistry, biology.protein, Diterpene, 010606 plant biology & botany

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcb1bfd5d193ee941c02619f1a064e9Test
https://doi.org/10.1186/s12870-019-1702-5Test