-
1
المؤلفون: Anne T. Nies, Elke Schaeffeler, Kathrin Klein, Kathleen M. Giacomini, Michel Eichelbaum, Matthias Schwab, Ute Hofmann, Claudia Neul, Stefan Winter
المصدر: British Journal of Pharmacology. 178:1459-1474
مصطلحات موضوعية: 0301 basic medicine, CYP2D6, SLC47A1, Organic Cation Transport Proteins, Pharmacology, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cations, medicine, Humans, Organic cation transport proteins, biology, Chemistry, Sparteine, Organic Cation Transporter 2, Cytochrome P450, Phenotype, 030104 developmental biology, Cytochrome P-450 CYP2D6, Pharmaceutical Preparations, Debrisoquine, Perhexiline, biology.protein, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3555d075053f2fad1daf3c8541155Test
https://doi.org/10.1111/bph.15370Test -
2
المؤلفون: Stefanie Brenner, Oliver Burk, Matthias Schwab, Svitlana Igel, Michel Eichelbaum, Ute Hofmann, M D Alscher, Heike Tegude
المصدر: Clinical Pharmacology & Therapeutics. 88:685-694
مصطلحات موضوعية: Adult, Male, Digoxin, Thyroid Hormones, endocrine system, medicine.medical_specialty, ATP Binding Cassette Transporter, Subfamily B, Cardiotonic Agents, endocrine system diseases, Administration, Oral, Pharmacology, Transfection, Hyperthyroidism, Young Adult, Hypothyroidism, Internal medicine, medicine, Humans, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, RNA, Messenger, Infusions, Intravenous, Aged, P-glycoprotein, Volume of distribution, Thyroid hormone receptor, biology, Rhodamines, Chemistry, Thyroid disease, Middle Aged, medicine.disease, Enhancer Elements, Genetic, Endocrinology, Gene Expression Regulation, Cell culture, biology.protein, Female, Efflux, Caco-2 Cells, Thyroid function, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979e84aee1420ec2c9457a4d22b14c2cTest
https://doi.org/10.1038/clpt.2010.176Test -
3
المؤلفون: Michael Dördelmann, Martin Schrappe, Sally A. Coulthard, Martin Zimmermann, Michel Eichelbaum, Anja Möricke, A. Reiter, G Cario, André Schrauder, Peter Kaatsch, Martin Stanulla, Karl Welte, Hansjörg Riehm, Matthias Schwab, Elke Schaeffeler
المصدر: Blood. 114:1314-1318
مصطلحات موضوعية: Male, Heterozygote, medicine.medical_specialty, Vincristine, Immunology, Biochemistry, Thiopurine S-Methyltransferase, Risk Factors, Germany, Internal medicine, Acute lymphocytic leukemia, Antineoplastic Combined Chemotherapy Protocols, medicine, Asparaginase, Humans, Child, Childhood Acute Lymphoblastic Leukemia, Genetics, Hematology, Thiopurine methyltransferase, biology, Brain Neoplasms, business.industry, Daunorubicin, Homozygote, Infant, Cancer, Myeloid leukemia, Neoplasms, Second Primary, Methyltransferases, Cell Biology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Leukemia, Myeloid, Acute, Child, Preschool, biology.protein, Prednisone, Female, business, Follow-Up Studies, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fa8227801ce7edaa3294860ca1b02aTest
https://doi.org/10.1182/blood-2008-12-193250Test -
4
المؤلفون: Heike Tegude, Ulrike Gradhand, Martin F. Fromm, Jörg König, Michel Eichelbaum, Oliver Burk
المصدر: Life Sciences. 80:1490-1494
مصطلحات موضوعية: Regulatory Sequences, Nucleic Acid, Transfection, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Genes, Reporter, Complementary DNA, Humans, Cloning, Molecular, General Pharmacology, Toxicology and Pharmaceutics, Luciferases, Gene, DNA Primers, Analysis of Variance, Messenger RNA, Reporter gene, biology, General Medicine, Molecular biology, chemistry, Regulatory sequence, ABCC3, biology.protein, Multidrug Resistance-Associated Proteins, Cytosine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9dcc1c4dc67bfc5a7bf4a29cafaa2bTest
https://doi.org/10.1016/j.lfs.2007.01.023Test -
5
المصدر: Breast Cancer Research and Treatment. 107:15-24
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Metabolite, Estrogen receptor, Breast Neoplasms, Protein Serine-Threonine Kinases, Biology, Transforming Growth Factor beta2, chemistry.chemical_compound, Cell Line, Tumor, Internal medicine, Biomarkers, Tumor, medicine, Humans, RNA, Messenger, skin and connective tissue diseases, Cell Proliferation, Receptor, Transforming Growth Factor-beta Type II, Cancer, Estrogens, Transforming growth factor beta, Antiestrogen, medicine.disease, Tamoxifen, Endocrinology, Models, Chemical, Oncology, chemistry, Selective estrogen receptor modulator, Cancer cell, Cancer research, biology.protein, Receptors, Transforming Growth Factor beta, Biomarkers, hormones, hormone substitutes, and hormone antagonists, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fec4a285a569846f31abf7cbfb12d50Test
https://doi.org/10.1007/s10549-007-9526-7Test -
6
المؤلفون: Leszek Wojnowski, Thomas Lang, Kari T. Kivistö, Pertti J. Neuvonen, Mikko Niemi, Janne T. Backman, Ulrich M. Zanger, Katja A. Arnold, Marja K. Pasanen, Ute Gödtel-Armbrust, Michel Eichelbaum
المصدر: University of Helsinki
مصطلحات موضوعية: Cmax, Gene Expression, Organic Anion Transporters, Single-nucleotide polymorphism, Pharmacology, Polymorphism, Single Nucleotide, Genetics, medicine, Humans, SNP, General Pharmacology, Toxicology and Pharmaceutics, Molecular Biology, Allele frequency, Cells, Cultured, Genetics (clinical), Pravastatin, Polymorphism, Genetic, biology, Liver-Specific Organic Anion Transporter 1, Haplotype, Genetic Variation, Membrane Transport Proteins, Multidrug Resistance-Associated Protein 2, Haplotypes, Liver, biology.protein, Molecular Medicine, Multidrug Resistance-Associated Proteins, SLCO1B1, Blood sampling, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99424af5867758664327a54b2d83a3ccTest
https://doi.org/10.1097/01.fpc.0000230422.50962.91Test -
7
المؤلفون: Martin F. Fromm, Georg Heinkele, Nicolas Simon, Ute Hofmann, Céline Verstuyft, Hartmut Glaeser, Monika Hitzl, Siegfried Drescher, Christian Schaefer, Thomas E. Mürdter, Oliver Burk, Michel Eichelbaum, Laurent Becquemont
المصدر: Clinical Pharmacology & Therapeutics. 79:449-460
مصطلحات موضوعية: Adult, Male, Digoxin, Midazolam, Enzyme Activators, In Vitro Techniques, Pharmacology, Cell Line, Cytochrome P-450 Enzyme System, Pharmacokinetics, Cell Line, Tumor, Leukocytes, medicine, Cytochrome P-450 CYP3A, Humans, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, RNA, Messenger, Intestinal Mucosa, P-glycoprotein, Pregnane X receptor, biology, CYP3A4, Chemistry, Ursodeoxycholic Acid, Ursodeoxycholic acid, Bioavailability, Intestines, Area Under Curve, biology.protein, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd638350525f5dd52169ddb3cf594f81Test
https://doi.org/10.1016/j.clpt.2006.01.005Test -
8
المؤلفون: Michel Eichelbaum, Klaus von Bergmann, Dieter Lütjohann, Mikko Niemi, Michael Igel, Kari T. Kivistö, Ute Hofmann, Katja A. Arnold, Matthias Schwab
المصدر: Clinical Pharmacology & Therapeutics. 79:419-426
مصطلحات موضوعية: Adult, medicine.medical_specialty, Organic anion transporter 1, Organic Anion Transporters, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, medicine, Humans, Pharmacology (medical), Prospective Studies, Pravastatin, Pharmacology, Polymorphism, Genetic, biology, Liver-Specific Organic Anion Transporter 1, Cholesterol, Cholesterol, LDL, Confidence interval, Organic anion-transporting polypeptide, Endocrinology, Haplotypes, chemistry, Biochemistry, Pharmacogenetics, Area Under Curve, biology.protein, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, SLCO1B1, Half-Life, Lipoprotein, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8d1067c789c20c065cbd8eea23e6fbTest
https://doi.org/10.1016/j.clpt.2006.01.010Test -
9
المؤلفون: Pertti J. Neuvonen, Kari T. Kivistö, Julian B. S. Leathart, Mikko Niemi, Mikko Neuvonen, Janne T. Backman, Lauri I. Kajosaari, Ann K. Daly, Michel Eichelbaum
المصدر: Clinical Pharmacology & Therapeutics. 77:468-478
مصطلحات موضوعية: Adult, Male, Genotype, Cmax, Single-nucleotide polymorphism, Biology, Pharmacology, Polymorphism, Single Nucleotide, Cytochrome P-450 CYP2C8, Cytochrome P-450 Enzyme System, Piperidines, Pharmacokinetics, medicine, Cytochrome P-450 CYP3A, Humans, Hypoglycemic Agents, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, CYP2C8, Liver-Specific Organic Anion Transporter 1, Repaglinide, Organic anion-transporting polypeptide, biology.protein, ATP-Binding Cassette Transporters, Female, Aryl Hydrocarbon Hydroxylases, Carbamates, Genes, MDR, SLCO1B1, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a3de8b68a232f7346fef6a9756f07cTest
https://doi.org/10.1016/j.clpt.2005.01.018Test -
10
المؤلفون: Ulrich M. Zanger, Michel Eichelbaum, Matthias Schwab, Tanja Richter
المصدر: Biochemical Pharmacology. 69:517-524
مصطلحات موضوعية: CYP2B6, ThioTEPA, Pharmacology, Hydroxylation, Biochemistry, law.invention, law, medicine, Humans, Enzyme Inhibitors, Bupropion, biology, Chemistry, Active site, Cytochrome P450, Oxidoreductases, N-Demethylating, Cytochrome P-450 CYP2B6, Mechanism of action, Suicide inhibition, biology.protein, Recombinant DNA, Microsome, Aryl Hydrocarbon Hydroxylases, medicine.symptom, Thiotepa, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d21ad87d3b786d87800f180e1d6e55Test
https://doi.org/10.1016/j.bcp.2004.10.008Test