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المؤلفون: Da Bin Kim, Myung-Shin Lee, Hong Seok Kim, Haeun Ko, Seung Ro Han, Jisu Lee, Yun Hee Kang, Seyoun Park
المصدر: Molecules and Cells
مصطلحات موضوعية: Male, mitogen-activated protein kinase phosphatase 3, DUSP6, Transfection, Mice, Cell Line, Tumor, Tumor Microenvironment, Animals, Humans, Protein kinase A, Molecular Biology, Tumor microenvironment, biology, Tumor hypoxia, hypoxia-inducible factor-1α, Kinase, Chemistry, hypoxia, Cell Biology, General Medicine, Cell Hypoxia, Cell biology, colon cancer, Tumor progression, Cancer cell, Colonic Neoplasms, biology.protein, MAPK phosphatase, Mitogen-Activated Protein Kinase Phosphatases, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a245422b5eee6f22763604fb186fffTest
http://europepmc.org/articles/PMC8560588Test -
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المؤلفون: Jessy V. van Asperen, Miriam E. van Strien, Emma J. van Bodegraven, Coen B J van Deursen, Oscar M. J. A. Stassen, Pierre A. Robe, Elly M. Hol, Jacqueline A. Sluijs
المساهمون: Cell-Matrix Interact. Cardiov. Tissue Reg.
المصدر: The FASEB Journal, 33(11), 12941-12959. FASEB
مصطلحات موضوعية: 0301 basic medicine, MAP Kinase Kinase 4, Biochemistry, Mitogen-Activated Protein Kinase Phosphatases/genetics, Extracellular matrix, 0302 clinical medicine, Phosphorylation, Intermediate filament, Cytoskeleton, Tumor, Glial fibrillary acidic protein, biology, Brain Neoplasms, Chemistry, cytoskeleton, Glioma, Gene Knockdown Techniques, Dual-Specificity Phosphatases, Glioma/metabolism, Biotechnology, intermediate filaments, extracellular matrix, Phosphatase, GFAP isoforms, Dual-Specificity Phosphatases/genetics, Cell Line, Focal adhesion, 03 medical and health sciences, glioblastoma multiforme, Cell Line, Tumor, Glial Fibrillary Acidic Protein, Genetics, medicine, Humans, Molecular Biology, Alternative splicing, Extracellular Matrix/metabolism, medicine.disease, Laminin/metabolism, Alternative Splicing, 030104 developmental biology, MAP Kinase Kinase 4/metabolism, Cancer research, biology.protein, Mitogen-Activated Protein Kinase Phosphatases, Laminin, Glial Fibrillary Acidic Protein/genetics, CRISPR-Cas Systems, 030217 neurology & neurosurgery, Brain Neoplasms/metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f98a81dfc825cd528e08052a5e406fTest
https://research.tue.nl/en/publications/4b991fe4-0534-4fa6-95b6-61354ccf9ca8Test -
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المؤلفون: Xiaowu Xu, Shunrong Ji, Zheng Zhang, Qifeng Zhuo, Wensheng Liu, Zeng Ye, Yi Qin, Wenyan Xu, Xianjun Yu, Mengqi Liu, Guixiong Fan, Qiangsheng Hu
المصدر: Cancer Letters. 499:265-278
مصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, Cancer Research, MAP Kinase Signaling System, Kaplan-Meier Estimate, Histones, Mice, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, Cell Line, Tumor, Biomarkers, Tumor, Animals, Humans, Gene silencing, Gene Silencing, Epigenetics, Promoter Regions, Genetic, STAT3, Pancreas, Cell Proliferation, biology, Cell growth, Chemistry, Gene Expression Profiling, Promoter, Histone-Lysine N-Methyltransferase, DNA Methylation, Prognosis, Xenograft Model Antitumor Assays, Up-Regulation, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, 030104 developmental biology, Oncology, Cell culture, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Phosphorylation, Chromatin immunoprecipitation, Carcinoma, Pancreatic Ductal
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510b8428592492f981d36b8533bc5fdcTest
https://doi.org/10.1016/j.canlet.2020.11.023Test -
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المؤلفون: Snehal Pandav Mudrale, Kakoli Bose, Saujanya Acharya, Shubhankar Dutta
المصدر: Biochemical and Biophysical Research Communications. 533:607-612
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Proteome, medicine.medical_treatment, PDZ domain, Biophysics, Computational biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Dual-specificity phosphatase, Human proteome project, medicine, Humans, Computer Simulation, Peptide library, Molecular Biology, Binding selectivity, Serine protease, Binding Sites, Protease, biology, Chemistry, Cell Biology, High-Temperature Requirement A Serine Peptidase 2, Ligand (biochemistry), 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec46789d5d32728c9f8e7fb7e6d2205Test
https://doi.org/10.1016/j.bbrc.2020.09.062Test -
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المؤلفون: Fabrice Valette, Pere Santamaria, Jean-François Bach, Claudio Scazzocchio, Sophie Candon, Sebastien Lemoine, Sara Hildebrand, Peipei Hu, Bruce Beutler, Sylvaine You, Francina Langa-Vives, Stephen Aplin Lyon, Anne-Perrine Foray, Eva Marie Y. Moresco, Chun Hui Bu, Lucienne Chatenoud, Coralie Pecquet, Darui Xu, Cindy Marquet, Michael Dumas, Lindsay Scott, Tao Wang
المساهمون: Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), University of Texas Southwestern Medical Center [Dallas], Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Institut Pasteur [Paris] (IP), Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)-Centre National de la Recherche Scientifique (CNRS), University of Calgary, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Imperial College London, Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Funding was provided by NIH Grant R01 AI125581 (B.B.), NIH Grant U19 AI100627 (B.B.), European Research Council Advanced Grant, Hygiene No. 250290 (J.-F.B.), Institut National de la Santé et de la Recherche Scientifique (L.C.), Fondation Day Solvay (L.C.), and the Lyda Hill Foundation (B.B.)., European Project: 250290,EC:FP7:ERC,ERC-2009-AdG,HYGIENE(2010), LANGA VIVES, FRANCINA, THE HYGIENE HYPOTHESIS : REVISITING THE CONCEPT BY INTEGRATING EPIDEMIOLOGY AND MECHANISTIC STUDIES - HYGIENE - - EC:FP7:ERC2010-08-01 - 2015-07-31 - 250290 - VALID
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (47), pp.e2112032118. ⟨10.1073/pnas.2112032118⟩
Proc Natl Acad Sci U S Aمصطلحات موضوعية: Male, type 1 diabetes, Nod, Major histocompatibility complex, medicine.disease_cause, Autoimmune Diseases, Major Histocompatibility Complex, Islets of Langerhans, Mice, Germline mutation, Mice, Inbred NOD, medicine, Animals, Humans, Missense mutation, Genetic Predisposition to Disease, Germ-Line Mutation, NOD mice, Autoimmune disease, Genetics, Mutation, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Multidisciplinary, biology, autoimmunity, Haplotype, Biological Sciences, medicine.disease, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, Haplotypes, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Female, genetic mapping, NOD mouse, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Genome-Wide Association Study
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ba665602db471fa72ce8128e19ff67Test
https://doi.org/10.1073/pnas.2112032118Test -
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المؤلفون: Zohra, Fatma, Grosset, Christophe, Khoubai, Fatma Zohra
المساهمون: Biothérapies des maladies génétiques et cancers, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Grosset, Christophe
المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11538. ⟨10.3390/ijms222111538⟩
International Journal of Molecular Sciences, Vol 22, Iss 11538, p 11538 (2021)مصطلحات موضوعية: Male, Models, Molecular, MAPK/ERK pathway, sex differences, mitogen-activated protein kinase, Protein Conformation, MAP kinase phosphatase, [SDV]Life Sciences [q-bio], Review, Mice, metabolic syndromes, 0302 clinical medicine, Neoplasms, Tissue Distribution, ASK1, Biology (General), Spectroscopy, Sex Characteristics, 0303 health sciences, biology, Kinase, Mouse Embryonic Stem Cells, General Medicine, 3. Good health, Computer Science Applications, Cell biology, [SDV] Life Sciences [q-bio], Chemistry, 030220 oncology & carcinogenesis, Mitogen-activated protein kinase, Dual-Specificity Phosphatases, Female, Metabolic Networks and Pathways, Heart Diseases, QH301-705.5, MAP Kinase Signaling System, p38 mitogen-activated protein kinases, Phosphatase, Gene Expression Regulation, Enzymologic, Catalysis, Inorganic Chemistry, 03 medical and health sciences, Metabolic Diseases, Dual-specificity phosphatase, Animals, Humans, cancer, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, 030304 developmental biology, therapy, Organic Chemistry, dual-specificity phosphatase, biology.protein, Mitogen-Activated Protein Kinase Phosphatases
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a51f0f6bbfcfdbca71a3650c71cbb9Test
https://www.hal.inserm.fr/inserm-03405063Test -
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المؤلفون: Hsiu-Ping Lin, Shauh-Der Yeh, Cheng-Wei Chang, Yu-Wen Su, Wen-Jye Lin, Tse-Hua Tan, Hui-Min Ho
المصدر: The FASEB Journal. 33:14653-14667
مصطلحات موضوعية: Male, 0301 basic medicine, Phosphatase, Biochemistry, Serine, Dephosphorylation, Mice, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Cell Line, Tumor, Dual-specificity phosphatase, Genetics, medicine, Animals, Humans, Phosphorylation, Tyrosine, Molecular Biology, Cell Proliferation, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, biology, Kinase, Chemistry, Prostatic Neoplasms, medicine.disease, ErbB Receptors, Mice, Inbred C57BL, 030104 developmental biology, Receptors, Androgen, Cancer research, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, 030217 neurology & neurosurgery, Protein Binding, Signal Transduction, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf6ed3e1b6ed025e887ebe11eab4192Test
https://doi.org/10.1096/fj.201802558rrTest -
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المؤلفون: Danian Ma, Lei Hong, Jiangbo Ai
المصدر: Biochemical and Biophysical Research Communications. 519:445-452
مصطلحات موضوعية: Male, 0301 basic medicine, Osteoporosis, Biophysics, Gene Expression, Osteoclasts, Bone Marrow Cells, Mice, Transgenic, AMP-Activated Protein Kinases, Biochemistry, Bone resorption, 03 medical and health sciences, 0302 clinical medicine, Skeletal disorder, Osteoclast, medicine, Animals, Bone Resorption, Molecular Biology, Cells, Cultured, biology, Chemistry, Macrophage Colony-Stimulating Factor, Macrophages, RANK Ligand, Cell Biology, medicine.disease, Cell biology, Enzyme Activation, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, RANKL, 030220 oncology & carcinogenesis, Chronic inflammatory response, biology.protein, MAP kinase phosphatase, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Signal transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e312c50b530195d45cc3686b2a51ccTest
https://doi.org/10.1016/j.bbrc.2019.07.091Test -
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المؤلفون: Tatiana Varela, Natércia Conceição, Vincent Laizé, M. Leonor Cancela
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: Hepatocyte Nuclear Factor 3-alpha, STAT3 Transcription Factor, CCCTC-Binding Factor, DUSP4, Apoptosis, Biochemistry, YY1, STAT3, Transcriptional regulation, Transcription (biology), Dual-specificity phosphatase, Humans, Promoter Regions, Genetic, Molecular Biology, Transcription factor, YY1 Transcription Factor, Cell Proliferation, Binding Sites, biology, Promoter, Cell Differentiation, Cell Biology, CTCF, Cell biology, HEK293 Cells, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, FOXA1
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5cc9f4f01fbea8e8edc350fef3feb3Test
https://pubmed.ncbi.nlm.nih.gov/34254709Test -
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المؤلفون: Meixue Yao, Haoran Bi, Guixiang Sun, Jun Song, Lin Cao, Yu Tang, Yefei Huang, Yan-Su Chen, Qinzhi Wang
المصدر: Ecotoxicology and Environmental Safety, Vol 214, Iss, Pp 112057-(2021)
مصطلحات موضوعية: Homeobox protein NANOG, Nicotine, Nitrosamines, MAP Kinase Signaling System, Colorectal cancer, Health, Toxicology and Mutagenesis, Cell, NNK, 0211 other engineering and technologies, DUSP4, 02 engineering and technology, 010501 environmental sciences, Stem cell marker, 01 natural sciences, Environmental pollution, Feedback, Cancer stem cell, Cell Line, Tumor, medicine, Humans, GE1-350, 0105 earth and related environmental sciences, 021110 strategic, defence & security studies, Mitogen-Activated Protein Kinase 3, biology, ERK1/2, Cancer stem cells, CD44, Public Health, Environmental and Occupational Health, Epithelial Cells, General Medicine, medicine.disease, Pollution, CRC, Environmental sciences, Hyaluronan Receptors, medicine.anatomical_structure, TD172-193.5, Carcinogens, Neoplastic Stem Cells, biology.protein, Cancer research, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Stem cell, Colorectal Neoplasms, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7172fbecc2d10c4c5a688b94523c5a9Test
http://www.sciencedirect.com/science/article/pii/S0147651321001688Test