نتائج البحث - "Kenneth P Nephew"

1

Combined epigenetic and metabolic inhibition blocks platinum-induced ovarian cancer stem cell enrichment

المؤلفون: Riddhi Sood, Shruthi Sriramkumar, Vaishnavi Muralikrishnan, Sikai Xiao, Weini Wang, Christiane Hassel, Kenneth P. Nephew, Heather M. O’Hagan

مصطلحات موضوعية: Methyltransferase, endocrine system diseases, biology, Chemistry, Aldehyde dehydrogenase, Promoter, medicine.disease, female genital diseases and pregnancy complications, DNA methylation, biology.protein, medicine, Cancer research, Epigenetics, NAD+ kinase, Stem cell, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3a81616bebba938563220f64e0c37b75Test
https://doi.org/10.1101/2021.03.18.435878Test

2

ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer

المصدر: Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, epithelial–mesenchymal–transition, Angiogenesis, Integrin, Tumor initiation, Biology, Cell morphology, lcsh:RC254-282, extracelluar matix, Metastasis, Extracellular matrix, cryogenic scanning electron microscopy (cryo-SEM), 03 medical and health sciences, 0302 clinical medicine, triple negative breast cancer (TNBC), medicine, metastasis, Epithelial–mesenchymal transition, Triple-negative breast cancer, Original Research, ERK5 kinase, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, clustered regularly interspaced short palindromic repeats (CRISPR) knockout

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d044e8ea69d15788ac4b6c96b76a55Test
https://doi.org/10.3389/fonc.2020.01164Test

3

Abstract 3095: Targeting ALDH1A1 and regulatory networks that support stemness in ovarian cancer cells

المؤلفون: Thomas D. Hurley, Kenneth P. Nephew, Vaishnavi Muralikrishnan

المصدر: Cancer Research. 81:3095-3095

مصطلحات موضوعية: Cancer Research, biology, Cellular differentiation, Aldehyde dehydrogenase, Cancer, medicine.disease, ALDH1A1, Oncology, Downregulation and upregulation, Cell culture, Cancer stem cell, Cancer research, biology.protein, medicine, Stem cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0deaa8d7f0c24a8f02995632ced03d55Test
https://doi.org/10.1158/1538-7445.am2021-3095Test

4

MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer

المؤلفون: Michael J. G. Milevskiy, Carolina Marques, Lez J. Burke, Andrew Stone, Udai Gujral, Melissa A. Brown, Kenneth P. Nephew, Susan J. Clark, Julia Margaret Wendy Gee, Korinne Northwood

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Transcriptional regulatory elements, Breast Neoplasms, Disease, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cyclin-dependent kinase, microRNA, medicine, Transcriptional regulation, Biomarkers, Tumor, Humans, Hox gene, Gene, 030304 developmental biology, Regulation of gene expression, Homeodomain Proteins, 0303 health sciences, Estrogen Receptor alpha, Cancer, DNA Methylation, medicine.disease, Prognosis, Chromatin, 3. Good health, Gene Expression Regulation, Neoplastic, MicroRNAs, Tamoxifen, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, DNA methylation, miRNAs, Cancer research, biology.protein, Disease Progression, MCF-7 Cells, Female

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf354db62e4060b6c0af4a8a66796d5Test

5

Abstract 498: Targeting EZH2/DAB2IP/C-JUN axis in ovarian cancer stem cells

المؤلفون: Weini Wang, Ali R. Özeş, Fang Fang, Xingyue Zong, Kenneth P. Nephew

المصدر: Cancer Research. 80:498-498

مصطلحات موضوعية: Cancer Research, biology, c-jun, LGR5, Cancer, medicine.disease, Metastasis, ALDH1A1, Oncology, Cell culture, medicine, biology.protein, Cancer research, Stem cell, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::18ad9ec796e32b12189ea926efba5105Test
https://doi.org/10.1158/1538-7445.am2020-498Test

6

Abstract B2-09: A systems biology approach to understanding estrogen responsiveness in breast cancer cells using the MCF7 model

المؤلفون: Ayesha N. Shajahan-Haq, Robert Clarke, Subha Madhavan, Amrita K. Cheema, David F.B. Miller, Yunlong Liu, Krithika Bhuvaneshwar, Jay Pilrose, Lu Jin, Lang Li, Simina M. Boca, Kenneth P. Nephew

المصدر: Cancer Research. 75:B2-09

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, biology, Systems biology, Phosphoproteomics, Cancer, medicine.disease, Transcriptome, Internal medicine, medicine, biology.protein, Cancer research, Aromatase, Transcription factor, Estrogen receptor alpha, Tamoxifen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4a2f2ffd0dd8d2e7252f307ebb2083feTest
https://doi.org/10.1158/1538-7445.compsysbio-b2-09Test

7

Abstract A81: Targeting EZH2/DAB2IP/Wnt axis in ovarian cancer stem cells

المؤلفون: Weini Wang, Ali R. Özeş, Xingyue Zong, Kenneth P. Nephew

المصدر: Clinical Cancer Research. 26:A81-A81

مصطلحات موضوعية: Cancer Research, biology, EZH2, LGR5, Wnt signaling pathway, Cancer, medicine.disease, Metastasis, ALDH1A1, Oncology, biology.protein, Cancer research, medicine, Stem cell, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4a12a6b4e4bcec60ef9f117f188116e0Test
https://doi.org/10.1158/1557-3265.ovca19-a81Test

8

Targeting Aldehyde Dehydrogenases to Eliminate Cancer Stem Cells in Gynecologic Malignancies

المؤلفون: Thomas D. Hurley, Kenneth P. Nephew, Vaishnavi Muralikrishnan

المصدر: Cancers
Cancers, Vol 12, Iss 961, p 961 (2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce482e7fd510d09c5a370a2efbb72ddaTest
https://doi.org/10.3390/cancers12040961Test

9

IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells

المؤلفون: Sumegha Mitra, Yinu Wang, Xingyue Zong, Daniela Matei, Anirban K. Mitra, Kenneth P. Nephew

المصدر: JCI insight. 3(23)

مصطلحات موضوعية: 0301 basic medicine, DNA (Cytosine-5-)-Methyltransferase 1, Epigenomics, STAT3 Transcription Factor, medicine.medical_treatment, Aldehyde Dehydrogenase 1 Family, 03 medical and health sciences, Mice, 0302 clinical medicine, Drug Therapy, Cell Line, Tumor, medicine, Tumor Microenvironment, Animals, Humans, Platinum, Ovarian Neoplasms, Tumor microenvironment, Mice, Inbred BALB C, biology, Chemistry, Interleukin-6, Cancer, Retinal Dehydrogenase, General Medicine, Neoplasms, Experimental, Aldehyde Dehydrogenase, DNA Methylation, medicine.disease, Up-Regulation, ALDH1A1, 030104 developmental biology, Cytokine, Hypomethylating agent, 030220 oncology & carcinogenesis, Cancer research, DNMT1, biology.protein, Azacitidine, Disease Progression, Neoplastic Stem Cells, Cytokines, Female, Immunotherapy, Stem cell, Ovarian cancer, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2f5f00596eda8e994c521598b862d7Test
https://pubmed.ncbi.nlm.nih.gov/30518684Test

10

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer

المؤلفون: Bridgette M. Collins-Burow, Lyndsay V. Rhodes, Matthew E. Burow, Elizabeth C. Martin, H. Chris Segar, Aaron Buechlein, Douglas B. Rusch, David F.B. Miller, Kenneth P. Nephew

المصدر: Oncotarget

مصطلحات موضوعية: Epithelial-Mesenchymal Transition, Triple Negative Breast Neoplasms, Biology, CDH1, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, isomiRs, Antigens, CD, Cell Movement, Cell Line, Tumor, Gene expression, microRNA, medicine, Humans, Epithelial–mesenchymal transition, Triple-negative breast cancer, 030304 developmental biology, Zinc Finger E-box Binding Homeobox 2, Homeodomain Proteins, rho Guanine Nucleotide Dissociation Inhibitor alpha, 0303 health sciences, star strand, miRNA biogenesis, Base Sequence, Mesenchymal stem cell, Twist-Related Protein 1, Nuclear Proteins, Zinc Finger E-box-Binding Homeobox 1, Forkhead Transcription Factors, Sequence Analysis, DNA, medicine.disease, Cadherins, Molecular biology, 3. Good health, Gene Expression Regulation, Neoplastic, Repressor Proteins, MicroRNAs, Oncology, 030220 oncology & carcinogenesis, triple negative breast cancer, Cancer research, biology.protein, MCF-7 Cells, Ectopic expression, Female, RHOGDI, Research Paper, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658b832ea6f4cadb92b9a146bd64956fTest
http://europepmc.org/articles/PMC4599295Test

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