نتائج البحث - "Kaixin Zhou"

1

Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study

المؤلفون: Anubha Mahajan, Reinhard W. Holl, Nienke van Leeuwen, Ewan R. Pearson, Leen M 't Hart, Julia C. Stingl, Simone P. Rauh, Adem Y. Dawed, Petra J. M. Elders, Kaixin Zhou, Robert W. Koivula, Neil Robertson, Paul W. Franks, Mark I. McCarthy, Angus G. Jones

المساهمون: General practice, APH - Health Behaviors & Chronic Diseases, Epidemiology and Data Science, APH - Methodology, Amsterdam Reproduction & Development (AR&D), ACS - Diabetes & metabolism

المصدر: Diabetes Care, 42(6), 1027-1033. American Diabetes Association Inc.
Dawed, A Y, Zhou, K, van Leeuwen, N, Mahajan, A, Robertson, N, Koivula, R, Elders, P J M, Rauh, S P, Jones, A G, Holl, R W, Stingl, J C, Franks, P W, McCarthy, M I, t Hart, L M, Pearson, E R & IMI DIRECT Consortium 2019, ' Variation in the plasma membrane monoamine transporter (PMAT) (encoded by SLC29A4) and organic cation transporter 1 (OCT1) (encoded by SLC22A1) and gastrointestinal intolerance to metformin in type 2 diabetes: An IMI direct study ', Diabetes Care, vol. 42, no. 6, pp. 1027-1033 . https://doi.org/10.2337/dc18-2182Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec4e226c2ae5b92504ee32870293f27Test
https://doi.org/10.2337/dc18-2182Test

2

Genome-Wide Meta-Analysis Identifies the Organic Anion-Transporting Polypeptide Gene SLCO1B1 and Statins as Modifiers of Glycemic Response to Sulfonylureas

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: medicine.medical_specialty, biology, business.industry, medicine.drug_class, Type 2 diabetes, medicine.disease, Sulfonylurea, Metformin, Diabetes mellitus, Meta-analysis, Internal medicine, biology.protein, Medicine, business, SLCO1B1, Glipizide, medicine.drug, Glycemic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ad3dd97b76368a7dc7b852b1495c0803Test
https://doi.org/10.2139/ssrn.3795315Test

3

Effect of Serotonin Transporter 5-HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study

المؤلفون: Roger Tavendale, Colin N. A. Palmer, Ewan R. Pearson, Kaixin Zhou, Tanja Dujic

المصدر: Diabetes Care. 39:1896-1901

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Serotonin uptake, Genotype, Gastrointestinal Diseases, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Article, Intestinal absorption, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Alleles, Serotonin transporter, Aged, Serotonin Plasma Membrane Transport Proteins, Advanced and Specialized Nursing, Polymorphism, Genetic, biology, business.industry, Odds ratio, Middle Aged, medicine.disease, Metformin, 3. Good health, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, Female, Serotonin, business, Octamer Transcription Factor-1, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7bbd70935d75cc2165f29d3b5a1d79Test
https://doi.org/10.2337/dc16-0706Test

4

Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors

المؤلفون: Zhuqing Zhang, Hong Yang, Kaixin Zhou, Yingxia Li, Weicheng Zhou, Ruiqi Liu, Mingming Zhang, Meiyu Geng, Xun Huang

المصدر: European journal of medicinal chemistry. 180

مصطلحات موضوعية: Antineoplastic Agents, 01 natural sciences, 03 medical and health sciences, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Structure–activity relationship, Humans, p300-CBP Transcription Factors, Epigenetics, Enzyme Inhibitors, Pyrazolones, 030304 developmental biology, Cell Proliferation, Pharmacology, 0303 health sciences, Histone Acetyltransferase p300, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, General Medicine, Histone acetyltransferase, 0104 chemical sciences, Blot, Molecular Docking Simulation, Biochemistry, Docking (molecular), Acetylation, Cancer cell, biology.protein, MCF-7 Cells, Drug Screening Assays, Antitumor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edac0ed1e1f48a4f1781c33b93f2452cTest
https://pubmed.ncbi.nlm.nih.gov/31787358Test

5

Variation in the plasma membrane monoamine transporter (PMAT, encoded in SLC29A4) and organic cation transporter 1 (OCT1, encoded in SLC22A1) and gastrointestinal intolerance to metformin in type 2 diabetes: an IMI DIRECT study

المؤلفون: Simone P. Rauh, Julia C. Stingl, Neil Robertson, Leen M 't Hart, Adem Y. Dawed, Anubha Mahajan, Petra J. M. Elders, Paul W. Franks, Nienke van Leeuwen, Mark I. McCarthy, Reinhard W. Holl, Ewan R. Pearson, Robert W. Koivula, Angus G. Jones, Kaixin Zhou

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e38473521fa34cd838e9bd6b882f89aTest

6

CYP2C8 and SLCO1B1 Variants and Therapeutic Response to Thiazolidinediones in Patients With Type 2 Diabetes

المؤلفون: Graham P. Leese, Roger Tavendale, Colin N. A. Palmer, Adem Y. Dawed, Kaixin Zhou, Louise A. Donnelly, Ewan R. Pearson, Fiona Carr

المصدر: Diabetes Care. 39:1902-1908

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Genotype, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, Polymorphism, Single Nucleotide, White People, Cytochrome P-450 CYP2C8, Rosiglitazone, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, CYP2C8, Aged, Glycemic, Advanced and Specialized Nursing, Pioglitazone, biology, Liver-Specific Organic Anion Transporter 1, business.industry, Middle Aged, medicine.disease, Treatment Outcome, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Scotland, Pharmacogenetics, Linear Models, biology.protein, Female, Thiazolidinediones, business, SLCO1B1, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb764263e5a431153855d0641daad2cTest
https://doi.org/10.2337/dc15-2464Test

7

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

المؤلفون: Kathleen M. Giacomini, Adriaan Kooy, Coen D.A. Stehouwer, MetGen Investigators, Valdis Pirags, Daniel M. Rotroff, Ivan Tkáč, Huan-Chieh Chien, Michael J. Wagner, Shiro Maeda, Federico Innocenti, Joline W.J. Beulens, Monique M. Hedderson, Eric L. Seiser, Sook Wah Yee, Bruno H. Stricker, Accord Investigators, Jozef Židzik, Leen M 't Hart, Rury R. Holman, Alison A. Motsinger-Reif, Jose C. Florez, Albert Hofman, Mattijs Out, Albert M. Levin, Christopher J. Groves, Michiaki Kubo, Longyang Wu, Catherine E. de Keyser, Ewan R. Pearson, Lisa Logie, Calum Sutherland, Sabina Semiz, Tanja Dujic, John S. Witte, Amanda J. Bennett, Kathleen A. Jablonski, Linda Zaharenko, Nienke van Leeuwen, Ling Chen, Dpp Investigators, Roger Tavendale, Ruth L. Coleman, Amber A. van der Heijden, Colin N. A. Palmer, Janis Klovins, Martin Javorský, Ron H.N. van Schaik, Mark I. McCarthy, L. Keoki Williams, Kaixin Zhou

المساهمون: Epidemiology, Clinical Chemistry, General practice, EMGO - Lifestyle, overweight and diabetes, Epidemiology and Data Science, MUMC+: HVC Pieken Maastricht Studie (9), RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, Interne Geneeskunde, MUMC+: MA Interne Geneeskunde (3)

المصدر: Nature Genetics, 48(9), 1055
Nature Genetics, 48(9), 1055-+. Nature Publishing Group
Nature Genetics, 48(9), 1055-1059. Nature Publishing Group
Zhou, K, Yee, S W, Seiser, E L, van Leeuwen, N, Tavendalel, R, Bennett, A J, Groves, C J, Coleman, R L, van der Heijden, A A, Beulens, J W, de Keyser, C E, Zaharenkoll, L, Rotroff', D M, Out, M, Jablonski, K A, Chen, L, Javorsky, M, Zidzik, J, Levin, A M, Williams, L K, Dujic, T, Semiz, S, Kubo, M, Chien, H-C, Maeda, S, Witte, J S, Wu, L, Tkac, I, Kooy, A, van Schaik, R H N, Stehouwer, C D A, Logie, L, Sutherland, C, Klovins, J, Pirags, V, Hofman, A, Stricker, B H, Motsinger-Reif, A A, Wagner, M J, Innocenti, F, Hart, L M, Holman, R R, McCarthy, M I, Hedderson, M M, Palmer, C N A, Florez, J C, Giacomini, K M & Pearson, E R 2016, ' Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin ', Nature Genetics, vol. 48, no. 9, pp. 1055-1059 . https://doi.org/10.1038/ng.3632Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d8e457d5e17ebbdb7b48c533893063Test
https://hdl.handle.net/1887/96245Test

8

Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary artery disease outcome during statin treatment

المؤلفون: Natalie R. van Zuydam, Louise A. Donnelly, Fiona Carr, Anke H. Maitland-van der Zee, Maarten Leusink, Kaixin Zhou, Folkert W. Asselbergs, Pieter A. Doevendans, Roger Tavendale, Anthonius de Boer, Colin N. A. Palmer, Olaf H. Klungel, Alex S. F. Doney, Andrew D. Morris, Ewan R. Pearson

المصدر: Pharmacogenetics and Genomics. 23:518-525

مصطلحات موضوعية: Male, medicine.medical_specialty, Genotype, Population, Coronary Artery Disease, Polymorphism, Single Nucleotide, Article, law.invention, Cohort Studies, Coronary artery disease, chemistry.chemical_compound, Diabetes mellitus genetics, Randomized controlled trial, law, Internal medicine, Diabetes Mellitus, Genetics, medicine, Humans, Genetic Predisposition to Disease, cardiovascular diseases, General Pharmacology, Toxicology and Pharmaceutics, education, Molecular Biology, Genetics (clinical), Randomized Controlled Trials as Topic, education.field_of_study, biology, Cholesterol, business.industry, Anticholesteremic Agents, Genetic Variation, Cholesterol, LDL, Odds ratio, Lipoprotein(a), medicine.disease, Observational Studies as Topic, Endocrinology, Scotland, chemistry, Linear Models, biology.protein, Molecular Medicine, Female, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, Pharmacogenetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53b0a46a700abad35878569f4d24714Test
https://doi.org/10.1097/fpc.0b013e3283642fd6Test

9

Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study

المؤلفون: Graham P. Leese, Andrew D. Morris, Mark I. McCarthy, Andrew T. Hattersley, Alex S. F. Doney, Colin N. A. Palmer, Charlotte H. Kimber, Louise A. Donnelly, Peter T. Donnan, Kaixin Zhou, Ewan R. Pearson

المصدر: Diabetes
Zhou, K, Donnelly, L A, Kimber, C H, Donnan, P T, Doney, A S F, Leese, G, Hattersley, A T, McCarthy, M I, Morris, A D, Palmer, C N A & Pearson, E R 2009, ' Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin : A GoDARTS study ', Diabetes, vol. 58, no. 6, pp. 1434-1439 . https://doi.org/10.2337/db08-0896Test

مصطلحات موضوعية: Research design, Drug, Blood Glucose, Male, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, Renal function, 030209 endocrinology & metabolism, Type 2 diabetes, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Genetics, Humans, Hypoglycemic Agents, Treatment Failure, 030304 developmental biology, Glycemic, media_common, Sequence Deletion, Glycated Hemoglobin, 0303 health sciences, Organic cation transport proteins, Polymorphism, Genetic, biology, Dose-Response Relationship, Drug, business.industry, nutritional and metabolic diseases, Genetic Variation, Middle Aged, medicine.disease, Metformin, 3. Good health, Endocrinology, Amino Acid Substitution, Diabetes Mellitus, Type 2, biology.protein, Regression Analysis, Female, business, medicine.drug, Octamer Transcription Factor-1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561cabab360f283d1b8fbd0ec8ebf6d4Test
https://pubmed.ncbi.nlm.nih.gov/19336679Test

10

Erratum: The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

المؤلفون: Eric Taylor, K. Rabin, Aisling Mulligan, Isabel Gabriëls, Lamprini Psychogiou, Lena Johansson, H-C Steinhausen, Ian W. Craig, Anne Weeks, Leonard C. Feldman, Keeley J. Brookes, Fernando Mulas, Ueli Mueller, Peter McGuffin, Vaheshta Sethna, Pak C. Sham, Marieke E. Altink, R. Barrett, J. Sorohan, Ana Miranda, N. Lowe, Alexander Heise, Penny Andreou, Louise Butler, Desmond Campbell, Michael Gill, Joseph A. Sergeant, Hanna Christiansen, Raoul Howe-Forbes, Rafaela Marco, Cathelijne J. M. Buschgens, Ellen A. Fliers, Isabelle Korn-Lubetzki, Richard P. Ebstein, Philip Asherson, Herbert Roeyers, Robert D. Oades, Kaixin Zhou, Raoul Arnold, Jo Knight, Tobias Banaschewski, Henrik Uebel, Xiaohui Xu, Ruud B. Minderaa, Wei J. Chen, Aribert Rothenberger, Margaret Thompson, She'era Medad, K. Fleischman, Barbara Franke, Richard Anney, Folkert Boer, Edmund J.S. Sonuga-Barke, Nanda Rommelse, Jonna Kuntsi, Iris Manor, Benjamin M. Neale, Jacques Eisenberg, Stephen V. Faraone, Robert Plomin, A. Goldfarb, Jan K. Buitelaar

المصدر: Molecular Psychiatry. 11:1139-1139

مصطلحات موضوعية: Genetics, Linkage disequilibrium, Candidate gene, biology, business.industry, medicine.disease, Cellular and Molecular Neuroscience, Psychiatry and Mental health, Conduct disorder, Dopamine, biology.protein, Medicine, Attention deficit hyperactivity disorder, Monoamine oxidase A, business, Association (psychology), Molecular Biology, Gene, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c5fdea098515d4673421590bac0fce96Test
https://doi.org/10.1038/sj.mp.4001902Test

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