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المؤلفون: Darby Ball, Naifu Zhang, Keith J. Olsen, Sheena D'Arcy, Sean J. Johnson
المصدر: Nucleic Acids Research. 50:4042-4053
مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, biology, Chemistry, Saccharomyces cerevisiae, DNA Helicases, Helicase, RNA, Deuterium Exchange Measurement, biology.organism_classification, Deuterium, RNA Helicase A, Exosome, Mass Spectrometry, DEAD-box RNA Helicases, Transfer RNA, biology.protein, Biophysics, Genetics, Hydrogen–deuterium exchange, Nucleic acid structure, RNA Helicases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81496dac5bb981d82fe90f4b10bbffcTest
https://doi.org/10.1093/nar/gkac170Test -
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المؤلفون: Juan Pablo Rincon Pabon, Clint Vorauer, Michael S. Wrigley, David D. Weis, Charlie C. Mundorff, Michael J. Watson, Miklos Guttman
المصدر: Journal of the American Society for Mass Spectrometry. 32:2386-2390
مصطلحات موضوعية: Protein Conformation, Swine, medicine.medical_treatment, Hydrogen Deuterium Exchange-Mass Spectrometry, Peptide, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Column (database), Pepsin, Structural Biology, medicine, Animals, Spectroscopy, chemistry.chemical_classification, Protease, Chromatography, biology, Chemistry, 010401 analytical chemistry, Proteins, Reproducibility of Results, Enzymes, Immobilized, Pepsin A, Peptide Fragments, 0104 chemical sciences, Rapid assessment, biology.protein, Hydrogen–deuterium exchange, Digestion, Chromatography, Liquid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8f2be57c27ab777cb70adfa2870237Test
https://doi.org/10.1021/jasms.1c00080Test -
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المصدر: J Am Soc Mass Spectrom
مصطلحات موضوعية: Hot Temperature, Time Factors, Hydrogen Deuterium Exchange-Mass Spectrometry, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Antibodies, Article, Protein Domains, Structural Biology, Diethyl Pyrocarbonate, Side chain, Spectroscopy, Protein therapeutics, biology, Chemistry, 010401 analytical chemistry, Deuterium Exchange Measurement, Model protein, 0104 chemical sciences, Deuterium, Covalent bond, Solvents, Biophysics, biology.protein, Hydrogen–deuterium exchange, Antibody, Rituximab
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40e80220ea5a4b849ccc6bb321cccc8Test
https://doi.org/10.1021/jasms.1c00072Test -
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المؤلفون: Lukas Uhrik, Kathryn L. Ball, Maciej Parys, David Argyle, Chris Nortcliffe, Barbara C. Ruetgen, Umesh Kalathiya, Borivoj Vojtesek, Pavlína Zatloukalová, Marta Nekulova, Mikolaj Kocikowski, Małgorzata Lisowska, Lenka Hernychová, Jakub Faktor, Ted R. Hupp, Robin Fåhraeus, Petr Müller
المصدر: Uhrik, L, Hernychova, L, Muller, P, Kalathiya, U, Lisowska, M M, Kocikowski, M, Parys, M, Faktor, J, Nekulova, M, Nortcliffe, C, Zatloukalova, P, Ruetgen, B, Fahraeus, R, Ball, K L, Argyle, D J, Vojtesek, B & Hupp, T 2021, ' Hydrogen Deuterium Exchange Mass Spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody ', Biochemical Journal, vol. 478, no. 1, pp. 99-120 . https://doi.org/10.1042/BCJ20200674Test
Biochemical Journalمصطلحات موضوعية: Protein Engineering, Biochemistry, Molecular Bases of Health & Disease, law.invention, 0302 clinical medicine, Structural Biology, Tandem Mass Spectrometry, law, Comparative medicine, Diagnostics & Biomarkers, Research Articles, Cancer, 0303 health sciences, Molecular Interactions, biology, Chemistry, Antibodies, Monoclonal, IgG binding, 030220 oncology & carcinogenesis, Recombinant DNA, Antibody, Immunoglobulin Heavy Chains, medicine.drug_class, Recombinant Fusion Proteins, Omics, Hydrogen Deuterium Exchange-Mass Spectrometry, lymphoma, chemical and pharmacologic phenomena, Monoclonal antibody, Immunoglobulin light chain, 03 medical and health sciences, hydrogen deuterium exchange mass spectrometry, Dogs, Antigen, Peptide Library, Cell Line, Tumor, medicine, Animals, Humans, CD20, Amino Acid Sequence, Molecular Biology, 030304 developmental biology, Cell Biology, Antigens, CD20, Molecular biology, Kinetics, monoclonal antibody, Immunoglobulin G, biology.protein, hydrogen deuterium, Immunoglobulin Light Chains, exchange mass spectrometry, Hydrogen–deuterium exchange, Paratope, Binding Sites, Antibody, comparative medicine, Chromatography, Liquid
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fb429b05c2a88b64c8dd71f33cada0Test
https://doi.org/10.1042/bcj20200674Test -
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المؤلفون: Christine Bee, Olafur S. Gudmundsson, Guodong Chen, Amy Jhatakia, Andy X. Deng, Natalie Bezman, Richard Y.-C. Huang, Yun Wang, Vangipuram S. Rangan, Shrikant Deshpande
المصدر: Journal of the American Society for Mass Spectrometry. 32:1567-1574
مصطلحات موضوعية: biology, Chemistry, Protein footprinting, medicine.drug_class, Hydrogen Deuterium Exchange-Mass Spectrometry, Human leukocyte antigen, Monoclonal antibody, Antibodies, Epitope, Epitopes, Epitope mapping, Biochemistry, Structural Biology, Blocking antibody, biology.protein, medicine, Humans, Hydrogen–deuterium exchange, Protein Footprinting, Antibody, NK Cell Lectin-Like Receptor Subfamily C, NK Cell Lectin-Like Receptor Subfamily D, Epitope Mapping, Spectroscopy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244d9a1f0bc932e2c7ea1e99d2b03c5eTest
https://doi.org/10.1021/jasms.0c00399Test -
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المؤلفون: Emily J. Thompson, Anthony T. Iavarone, Wenju Zhang, Shuaihua Gao, Judith P. Klinman, Samuel L Barrow
المصدر: J Am Chem Soc
مصطلحات موضوعية: Adenosine, Adenosine Deaminase, Hydrogen Deuterium Exchange-Mass Spectrometry, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Catalysis, Substrate Specificity, Mice, Colloid and Surface Chemistry, Reaction rate constant, Protein structure, Hydrolase, TIM barrel, Animals, Enzyme kinetics, Binding site, Binding Sites, biology, Chemistry, Temperature, Active site, General Chemistry, Protein Structure, Tertiary, 0104 chemical sciences, Kinetics, Deamination, Biocatalysis, Mutagenesis, Site-Directed, biology.protein, Biophysics, Hydrogen–deuterium exchange
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0095afe4062f89d729afbad913aba0f5Test
https://doi.org/10.1021/jacs.0c07866Test -
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المصدر: ACS Chem Neurosci
مصطلحات موضوعية: Gene isoform, Physiology, Cognitive Neuroscience, Kinetics, Mutant, Peptide, Biochemistry, Article, 03 medical and health sciences, Residue (chemistry), 0302 clinical medicine, Alzheimer Disease, Amyloid precursor protein, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Amyloid beta-Peptides, biology, Deuterium Exchange Measurement, Cell Biology, General Medicine, Deuterium, Peptide Fragments, In vitro, chemistry, Biophysics, biology.protein, Hydrogen–deuterium exchange, 030217 neurology & neurosurgery, Hydrogen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b75628e276ac4f16ab8c107ac0905a3Test
https://doi.org/10.1021/acschemneuro.1c00072Test -
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المؤلفون: Bernice Yeung, Lionel Sison, Siyang Peter Li, Xuesong Scott Li, Christopher S. Barton, Shiaw-Lin Wu, Brian Flaherty, Qiaozhen Lu
المصدر: Analytical Chemistry. 92:8306-8314
مصطلحات موضوعية: Models, Molecular, Glycan, Glycosylation, biology, Idursulfase, Stereochemistry, Chemistry, 010401 analytical chemistry, Hydrogen Deuterium Exchange-Mass Spectrometry, Iduronate Sulfatase, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Recombinant Proteins, 0104 chemical sciences, Analytical Chemistry, carbohydrates (lipids), chemistry.chemical_compound, Cell Line, Tumor, medicine, biology.protein, Humans, Hydrogen–deuterium exchange, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc473d39d05aa39ece71b1f5cb1ff9eTest
https://doi.org/10.1021/acs.analchem.0c00661Test -
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المؤلفون: Yuanyuan Zhang, Yiluan Ding, Wen Li, C.Q. Liu, Hong-Bo Wang, Kaixian Chen, Jie Zheng, X. H. Zhou, Cheng Luo, Naixia Zhang, Hualiang Jiang, Liping Liao, Zhong-Ya Sun, Yanjun Liu, Jing Lu, Kehao Zhao, Ning Song, Senhao Xiao
المصدر: Acta Pharmacol Sin
مصطلحات موضوعية: Male, 0301 basic medicine, Magnetic Resonance Spectroscopy, Drug Evaluation, Preclinical, Hydrogen Deuterium Exchange-Mass Spectrometry, Dehydrogenase, Real-Time Polymerase Chain Reaction, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, stomatognathic system, Glyceraldehyde, Organometallic Compounds, Animals, Humans, Pharmacology (medical), Glycolysis, Lactic Acid, Glyceraldehyde 3-phosphate dehydrogenase, Pharmacology, chemistry.chemical_classification, biology, Glyceraldehyde-3-Phosphate Dehydrogenases, General Medicine, Hydrolyzable Tannins, Mice, Inbred C57BL, Glucose, 030104 developmental biology, Enzyme, Biochemistry, chemistry, Anaerobic glycolysis, 030220 oncology & carcinogenesis, biology.protein, NAD+ kinase, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), Cysteine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64275de0ff03cbcfc5c183a3d6e62153Test
https://doi.org/10.1038/s41401-021-00653-0Test -
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المؤلفون: Yining Huang, Tun Liu, Michael L. Gross, Nicole D. Wagner
المصدر: J Am Soc Mass Spectrom
مصطلحات موضوعية: Models, Molecular, Protein glycosylation, Glycosylation, Hydrogen Deuterium Exchange-Mass Spectrometry, 010402 general chemistry, 01 natural sciences, Article, chemistry.chemical_compound, Structural Biology, Humans, Cytotoxicity, Spectroscopy, Glycoproteins, chemistry.chemical_classification, Antibody-dependent cell-mediated cytotoxicity, biology, Chemistry, Receptors, IgG, 010401 analytical chemistry, Fc gamma receptor IIIa, 0104 chemical sciences, Biochemistry, Immunoglobulin G, biology.protein, Fc-Gamma Receptor, Binding Sites, Antibody, Antibody, Glycoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83051a40d89c41ffceb203011e7b7d3eTest
https://doi.org/10.1021/jasms.1c00003Test
